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Author: Richard A. Rettig Publisher: Oxford University Press ISBN: 0190293217 Category : Medical Languages : en Pages : 368
Book Description
In the late 1980s, a promising new treatment for breast cancer emerged: high-dose chemotherapy with autologous bone marrow transplantation or HDC/ABMT. By the 1990s, it had burst upon the oncology scene and disseminated rapidly before having been carefully evaluated. By the time published studies showed that the procedure was ineffective, more than 30,000 women had received the treatment, shortening their lives and adding to their suffering. This book tells of the rise and demise of HDC/ABMT for metastatic and early stage breast cancer, and fully explores the story's implications, which go well beyond the immediate procedure, and beyond breast cancer, to how we in the United States evaluate other medical procedures, especially life-saving ones. It details how the factors that drove clinical use--patient demand, physician enthusiasm, media reporting, litigation, economic exploitation, and legislative and administrative mandates--converged to propel the procedure forward despite a lack of proven clinical effectiveness. It also analyzes the limited effect of technology assessments before randomized clinical trials evaluated decisively the procedure and the ramifications of this system on healthcare today. Sections of the book consider the initial conditions surrounding the emergence of the new breast cancer treatment, the drivers of clinical use, and the struggle for evidence-based medicine. A concluding section considers the significance of the story for our healthcare system.
Author: Richard A. Rettig Publisher: Oxford University Press ISBN: 0190293217 Category : Medical Languages : en Pages : 368
Book Description
In the late 1980s, a promising new treatment for breast cancer emerged: high-dose chemotherapy with autologous bone marrow transplantation or HDC/ABMT. By the 1990s, it had burst upon the oncology scene and disseminated rapidly before having been carefully evaluated. By the time published studies showed that the procedure was ineffective, more than 30,000 women had received the treatment, shortening their lives and adding to their suffering. This book tells of the rise and demise of HDC/ABMT for metastatic and early stage breast cancer, and fully explores the story's implications, which go well beyond the immediate procedure, and beyond breast cancer, to how we in the United States evaluate other medical procedures, especially life-saving ones. It details how the factors that drove clinical use--patient demand, physician enthusiasm, media reporting, litigation, economic exploitation, and legislative and administrative mandates--converged to propel the procedure forward despite a lack of proven clinical effectiveness. It also analyzes the limited effect of technology assessments before randomized clinical trials evaluated decisively the procedure and the ramifications of this system on healthcare today. Sections of the book consider the initial conditions surrounding the emergence of the new breast cancer treatment, the drivers of clinical use, and the struggle for evidence-based medicine. A concluding section considers the significance of the story for our healthcare system.
Author: Robbie F. Castleman Publisher: InterVarsity Press ISBN: 9780830819584 Category : Religion Languages : en Pages : 184
Book Description
Robbie Castleman believes reclaiming purity in relationships is a journey toward holiness. In sprightly, straight-for-the-target prose, she shows how unmarried Christians can wait until marriage without turning into prudes or wallflowers.
Author: Meli Raine Publisher: Meli Raine ISBN: Category : Fiction Languages : en Pages : 242
Book Description
She thinks she’s fooled me. But I’ve known all along. Almost. Lily is hiding something, a secret so big, she came out of a year-long coma and her first instinct was to lie. Who does that? Someone who is afraid. No—not afraid. Terrified. And it’s my job to take that fear away. My partner and I have spent countless man-hours hunting down the cold-blooded killer who did this to her. Meanwhile, Lily’s spent her waking hours recovering. Getting stronger. Getting smarter. Staying beautiful. Never get involved emotionally. That’s my dictate. Never get attached. When you realize you’re caught in a triangle, it turns out there is no exit. Crossing a line is easy. Holding a line takes strength. Lily’s shooter knows that she’s my weakness. And he’s about to exploit that by breaking a line and escaping, claiming a hostage in the process. One I have to get back. No matter what it takes. False Hope is book 2 in the False trilogy by USA Today bestselling author Meli Raine.
Author: Lori Allen Publisher: Stanford University Press ISBN: 1503614190 Category : History Languages : en Pages : 481
Book Description
This book offers a provocative retelling of Palestinian political history through an examination of the international commissions that have investigated political violence and human rights violations. More than twenty commissions have been convened over the last century, yet no significant change has resulted from these inquiries. The findings of the very first, the 1919 King-Crane Commission, were suppressed. The Mitchell Committee, convened in the heat of the Second Intifada, urged Palestinians to listen more sympathetically to the feelings of their occupiers. And factfinders returning from a shell-shocked Gaza Strip in 2008 registered their horror at the scale of the destruction, but Gazans have continued to live under a crippling blockade. Drawing on debates in the press, previously unexamined UN reports, historical archives, and ethnographic research, Lori Allen explores six key investigative commissions over the last century. She highlights how Palestinians' persistent demands for independence have been routinely translated into the numb language of reports and resolutions. These commissions, Allen argues, operating as technologies of liberal global governance, yield no justice—only the oppressive status quo. A History of False Hope issues a biting critique of the captivating allure and cold impotence of international law.
Author: Daniel Callahan Publisher: Rutgers University Press ISBN: 9780813526744 Category : Health care reform Languages : en Pages : 340
Book Description
This text exposes the cause of the health care crisis and proposes an alternative to make care affordable and available to all. It shows how the quest for perfection is the core of the crisis, and suggests a medicine that bows to the limits of human nature and gives priority to meeting basic needs.
Author: Jeremy Snyder Publisher: Oxford University Press ISBN: 0197501281 Category : Medical Languages : en Pages : 256
Book Description
We often hear stories of people in terrible and seemingly intractable situations who are preyed upon by someone offering promises of help. Frequently these cases are condemned in terms of "exploiting hope." These accusations are made in a range of contexts: human smuggling, employment relationships, unproven medical 'cures.' We hear this concept so often and in so many contexts that, with all its heavy lifting in public discourse, its actual meaning tends to lose focus. Despite its common use, it can be hard to understand precisely what is wrong about exploiting hope what can accurately be captured under this concept, and what should be done. In this book, philosopher Jeremy Snyder offers an in-depth study of hope's exploitation. First, he examines the concept in the abstract, including a close look at how this term is used in the popular press and analysis of the concepts of exploitation and hope. This theory-based section culminates in a definitive account of what it is to exploit hope, and when and why doing so is morally problematic. The second section of the book examines the particularly dangerous cases in which unproven medical interventions target the most vulnerable: for example, participants in clinical trials, purchasing unproven stem cell interventions, "right to try" legislation, and crowdfunding for unproven medical interventions. This book is essential reading for ethical theorists, policymakers, and health researchers, on a topic of growing visibility and importance.
Author: Richard S. Lazarus Publisher: Oxford University Press ISBN: 0198024835 Category : Psychology Languages : en Pages : 332
Book Description
When Oxford published Emotion and Adaptation, the landmark 1991 book on the psychology of emotion by internationally acclaimed stress and coping expert Richard Lazarus, Contemporary Psychology welcomed it as "a brightly shining star in the galaxy of such volumes." Psychiatrists, psychologists and researchers hailed it as a masterpiece, a major breakthrough in our understanding of the emotional process and its central role in our adaptation as individuals and as a species. What was still needed, however, was a book for general readers and health care practitioners that would dispel the myths still surrounding cultural beliefs about emotion and systematically explain the relevance of the new research to the emotional dramas of our everyday lives. Now, in Passion and Reason, Lazarus draws on his four decades of pioneering research to bring readers the first book to move beyond both clinical jargon and "feel-good" popular psychology to really explain, in plain, accessible language, how emotions are aroused, how they are managed, and how they critically shape our views of ourselves and the world around us. With his co-author writer Bernice Lazarus, Dr. Lazarus explores the latest findings on the short and long-term causes and effects of various emotions, including the often conflicting research on stress management and links between negative emotions and heart disease, cancer, and other aspects of physical and psychological health. Lazarus makes a strong case that contrary to common assumption, emotions are not irrational--our emotions and our analytical thought processes are inextricably linked. While not a "how-to" book, Passion and Reason does describe how readers can interpret what lies behind their own emotions and those of their families, friends, and co-workers, and how to manage them more effectively. Exploring fifteen emotions in depth, from love to jealousy, the authors show how the personal meaning we give to the events and conditions of our lives trigger such emotions as anger, anxiety, guilt, and pride. They provide fascinating vignettes to frame a "biography" of each emotion. Some are composite case histories drawn from Dr. Lazarus's long career, but most are stories of people the Lazaruses have known over the years--people whose emotional fears, conflicts, and desires mirror readers' own. The Lazaruses also offer a special chapter on the diverse strategies of coping people use in managing their emotions, and another, "When Coping Fails," on psychotherapy and its approaches to emotional stress and dysfunction, from traditional Freudian psychoanalysis to continuing research into relaxation techniques, meditation, hypnosis, and biofeedback. Packed with insight and compellingly readable, Passion and Reason will enrich all readers fascinated by our emotional lives.
Author: Richard A. Rettig
Author: Richard A. Rettig
Author: Robbie F. Castleman
Author: Meli Raine
Author: Lori Allen
Author: 
Author: Curtis Hutson
Author: Daniel Callahan
Author: Laura Kightlinger
Author: Jeremy Snyder
Author: Richard S. Lazarus