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Author: Joan Gil Publisher: CRC Press ISBN: 1000147401 Category : Medical Languages : en Pages : 1026
Book Description
This research-level reference provides a review of the morphological techniques that have become a primary method of anatomical study correlating structure and function in lung physiology and pathology. Detailing the evolution of anatomy as a research discipline, it explores general structural techn
Author: Joan Gil Publisher: CRC Press ISBN: 1000147401 Category : Medical Languages : en Pages : 1026
Book Description
This research-level reference provides a review of the morphological techniques that have become a primary method of anatomical study correlating structure and function in lung physiology and pathology. Detailing the evolution of anatomy as a research discipline, it explores general structural techn
Author: Joan Gil Publisher: CRC Press ISBN: 9780367403157 Category : Languages : en Pages : 1032
Book Description
This research-level reference provides a review of the morphological techniques that have become a primary method of anatomical study correlating structure and function in lung physiology and pathology. Detailing the evolution of anatomy as a research discipline, it explores general structural techn
Author: Jerome Owen Cantor Publisher: CRC Press ISBN: 1351079417 Category : Medical Languages : en Pages : 252
Book Description
This two-volume handbook provides important information concerning the development, implementation, evaluation, uses, advantages, and limitations of a wide variety of animal model of pulmonary disease. While the work focuses on stepwise procedures for inducing and quantifying disease, additional emphasis is placed on each model's relationship to human counterparts and on comparisons with similar models of injury. Thus, even the novice researcher will be able to more sharply define a particular research question, find suitable animal models for study, gain access to specialized techniques, and evaluate results within the context of an up-to-date body of information about related forms of lung diseases.
Author: Jerome Owen Cantor Publisher: CRC Press ISBN: 9780849329784 Category : Medical Languages : en Pages : 256
Book Description
This two-volume handbook provides important information concerning the development, implementation, evaluation, uses, advantages, and limitations of a wide variety of animal model of pulmonary disease. While the work focuses on stepwise procedures for inducing and quantifying disease, additional emphasis is placed on each model's relationship to human counterparts and on comparisons with similar models of injury. Thus, even the novice researcher will be able to more sharply define a particular research question, find suitable animal models for study, gain access to specialized techniques, and evaluate results within the context of an up-to-date body of information about related forms of lung diseases.
Author: Jerome Owen Cantor Publisher: ISBN: 9781351070973 Category : HEALTH & FITNESS Languages : en Pages : 266
Book Description
"This two-volume handbook provides important information concerning the development, implementation, evaluation, uses, advantages, and limitations of a wide variety of animal model of pulmonary disease. While the work focuses on stepwise procedures for inducing and quantifying disease, additional emphasis is placed on each model's relationship to human counterparts and on comparisons with similar models of injury. Thus, even the novice researcher will be able to more sharply define a particular research question, find suitable animal models for study, gain access to specialized techniques, and evaluate results within the context of an up-to-date body of information about related forms of lung diseases."--Provided by publisher.
Author: Chelsea M. Magin Publisher: Springer Nature ISBN: 3031266250 Category : Science Languages : en Pages : 330
Book Description
Cutting-edge engineering approaches towards modelling lung homeostasis and disease have created dynamic new opportunities for interdisciplinary collaboration and unprecedented progress toward understanding and treating lung disease. This text connects established research in lung biology and physiology to innovative engineering strategies for pulmonary modelling. This unique approach aims to encourage and facilitate progress among a greater audience of basic and translational scientists, clinicians, and medical practitioners. Engineering Translational Models of Lung Homeostasis and Disease illustrates the advances in lung tissue characterization, revealing dynamic changes in the structure, mechanics, and composition of the extracellular matrix. This information paves the way for tissue-informed engineering models of pulmonary tissue, improved design of clinical materials, and advances against a variety of common pathologies. Current translational challenges are highlighted, as are engineering opportunities to overcome these barriers. This foundational text holds valuable lessons for researchers and clinicians throughout the fields of engineering, materials science, cell biology, pulmonary medicine, and clinical science. · Each section focuses on a specific region of the lung, presenting either the biological or clinical perspective along with complimentary engineering approaches · Covers the interface of engineering and lung biology · Highlights emerging new models to study lung disease and repair Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com
Author: Gunilla Westergren-Thorsson Publisher: Academic Press ISBN: 0323908721 Category : Medical Languages : en Pages : 262
Book Description
3D Lung Models for Regenerating Lung Tissue is a comprehensive summary on the current state of art 3D lung models and novel techniques that can be used to regenerate lung tissue. Written by experts in the field, readers can expect to learn more about 3D lung models, novel techniques including bioprinting and advanced imaging techniques, as well as important knowledge about the complexity of the lung and its extracellular matrix composition. Structured into 15 different chapters, the book spans from the original 2D cell culture model on plastic, to advanced 3D lung models such as using human extracellular matrix protein. In addition, the last chapters cover new techniques including 3D printing, bioprinting, and artificial intelligence that can be used to drive the field forward and some future perspectives. This highly topical book with chapters on everything from the complexity of the lung and its microenvironment to cutting-edge 3D lung models, represents an exciting body of work that can be used by researchers during study design, grant writing, as teaching material, or to stay updated with the progression of the field. A comprehensive summary of advanced 3D lung models written by the experts in the respiratory field Explore novel techniques that can be used to evaluate and improve 3D lung models, including techniques such as 3D printing, bioprinting, and artificial intelligence Explains what extracellular matrix is, the complexity of the lung microenvironment, and why this knowledge is important for creating a functional bioartificial lung
Author: Janette K. Burgess Publisher: Frontiers Media SA ISBN: 2832544177 Category : Science Languages : en Pages : 180
Book Description
The mechanisms underlying acute and chronic lung diseases are complex, reflecting the interplay between multiple cell types, their microenvironment and exogenous challenges. While traditional in vitro cell culture approaches have been instrumental in advancing our knowledge of cellular signalling and function, they typically lack the cell-cell and cell-matrix interactions that define the niche in which lung cell and tissue functions emerge. Implementing in vivo and ex vivo three-dimensional (3D) models more realistically mimicking the in vivo cell-extracellular matrix (ECM) crosstalk should facilitate a considerable leap towards better understanding lung diseases and thus in investigating new pharmacological tools. We are experiencing a revolution in our understanding of the cell types that deposit and remodel ECM in the lung, the dynamic spatial composition of the ECM and cell-cell interactions during disease, and the influence of ECM and cell-derived cues on lung cell biology. In concert, the ex vivo and in vitro models that are being used to examine the role of the 3D microenvironment of the cell in the lung are rapidly developing. The European Respiratory Society has partnered with Frontiers in Pharmacology to launch this research topic in conjunction with the ERS Research Seminar “Innovative 3D models for understanding mechanisms underlying lung diseases: powerful tools for translational research”.
Author: J.J. Marini Publisher: Springer Science & Business Media ISBN: 3642607330 Category : Medical Languages : en Pages : 466
Book Description
To integrate current knowledge in terms of basic and clinical science and to highlight problems, thirty world-renowned experts in the field of acute lung injury describe the state of up to date knowledge regarding the epidemiology, pathophysiology, and clinical management of acute lung injury. Novel techniques for the clinical support of these difficult patients are discussed in full. Prospects for successful pharmacological intervention are also outlined. This book is aimed at those practising within the field of critical care and is likely to become an indispensable aid to all concerned with the investigation and management of patients with severe respiratory failure.
Author: Joan Gil
Author: Joan Gil
Author: Joan Gil
Author: Jerome Owen Cantor
Author: Jerome Owen Cantor
Author: Jerome Owen Cantor
Author: Chelsea M. Magin
Author: Gunilla Westergren-Thorsson
Author: Janette K. Burgess
Author: J.J. Marini
Author: