Clinical Safety and Efficacy Testing of Cosmetics PDF Download

Author: William Waggoner
Publisher: CRC Press
ISBN: 9780824779412
Category : Medical
Languages : en
Pages : 350

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Author: Joachim W. Fluhr
Publisher: Springer Science & Business Media
ISBN: 3642050670
Category : Medical
Languages : en
Pages : 262

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Book Description
Skin physiology assessment is moving rapidly from a descriptive approach to a deeper understanding of biophysical and biochemical processes in the stratum corneum, e.g. on stratum corneum barrier function as well on stratum corneum hydration. The research with bioengineering methods offers now reliable and reproducible approaches for product testing in the pharmaceutical and cosmetic industry as well as in basic research. This cookbook is intended to give basic information regarding skin physiology, the assessment of skin functions in controlled studies using non-invasive biophysical instruments. It provides basic knowledge on how to plan, perform and evaluate scientific studies. The authors are recognized expert in the field and provide comprehensive chapters with specific emphasis on the practical aspects of non-invasive measurements.

Author: P. Elsner
Publisher: Springer Science & Business Media
ISBN: 3642598692
Category : Medical
Languages : en
Pages : 325

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Book Description
th Together with the 6 Amendment - Council Directive 93/35 EEC - to the Cosmetic Directive 76/768 EEC it was the first time that, according to Article 7b, special claims of efficacy could be legally attributed to cosmetic products but under the obligation to make evidence of the claimed effects; also an entirely new "controller" was introduced - the independent "safety assessor", This indeed means not only progress in reliable and honest marketing arguments but above all transparency as to the respective proof and thus protection of consumer's health. Such claims demand high standards in scientifi cally based methodology and their results in order to prove such demands evidently. There are also within the 6" Amendment to the Cosmetic Directive in Article 4a strict restrictions as to the further use of conventional animal testing for cosmetic pro ducts and their ingredients and especially for finished products. Without doubt there is a competition between the necessity and expectations on consumer health on the one hand and the requirements of acknowledged protection of animals as done in Council Directive 86/609 EEC on the other. But at least, based on the present state of knowledge, tests in human beings cannot replace animal testing in all instances. Not only ethical reasons alone prohibit or impede testing in humans but also very often the lack of knowledge on functional and/or biological processes underlaying observed effects with the consequence that suitable experimental methodologies are missing.

Author: Harry Salem
Publisher: CRC Press
ISBN: 9781560326236
Category : Medical
Languages : en
Pages : 456

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Book Description
Presents up-to-date concepts and approaches to the theory and practice of alternatives to animal testing and promotes technology transfer. The text addresses some of the ramifications of the National Institutes of Health Revitalization Act of 1993 which instructs the NIH to fund replacement, reduction and refinement alternatives. It also describes the likely impact of the European Union's Cosmetic Directive, which bans marketing of animal tested cosmetics in Europe after 1997 if alternatives are available. Contributions are grouped into five categories including: dermal toxicity; immunotoxicity; neurotoxicity; and oral/dermal/ocular validation.

Author: Albert M. Kligman
Publisher: Saunders
ISBN: 9780808915270
Category : Medical
Languages : en
Pages : 411

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Author: National Research Council
Publisher: National Academies Press
ISBN: 0309101174
Category : Science
Languages : en
Pages : 23

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Book Description
Science, Medicine, and Animals explains the role that animals play in biomedical research and the ways in which scientists, governments, and citizens have tried to balance the experimental use of animals with a concern for all living creatures. An accompanying Teacher's Guide is available to help teachers of middle and high school students use Science, Medicine, and Animals in the classroom. As students examine the issues in Science, Medicine, and Animals, they will gain a greater understanding of the goals of biomedical research and the real-world practice of the scientific method in general. Science, Medicine, and Animals and the Teacher's Guide were written by the Institute for Laboratory Animal Research and published by the National Research Council of the National Academies. The report was reviewed by a committee made up of experts and scholars with diverse perspectives, including members of the U.S. Department of Agriculture, National Institutes of Health, the Humane Society of the United States, and the American Society for the Prevention of Cruelty to Animals. The Teacher's Guide was reviewed by members of the National Academies' Teacher Associates Network. Science, Medicine, and Animals is recommended by the National Science Teacher's Association NSTA Recommends.

Author: Robert Baran
Publisher: CRC Press
ISBN: 1482257351
Category : Medical
Languages : en
Pages : 594

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Book Description
This text documents the science that lies behind the expanding field of cosmetic dermatology so that clinicians can practice with confidence and researchers can be fully aware of the clinical implications of their work. New chapters have been added to this edition on photodamage, actinic keratoses, UV lamps, hidradenitis suppurativa, age-related changes in male skin, changes in female hair with aging, nonabltaive laser rejuvenation, and cryolipolysis, and chapters have been updated throughout to keep this at the forefront of work and practice. The Series in Cosmetic and Laser Therapy is published in association with the Journal of Cosmetic and Laser Therapy. Print Versions of this book also include access to the ebook version.

Author: Francis Nicholas Marzulli
Publisher: CRC Press
ISBN: 9781560320555
Category : Medical
Languages : en
Pages : 1978

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Book Description
A guide to the field of dermatotoxicology. This edition includes fundamental information on the mechanisms of action of toxic substances on skin as well as practical information on the varied responses of skin to specific toxic substances and approaches to evaluating dermal toxicity. Other topics discussed include: hostile natural elements, such as ultraviolet radiation, poisonous plants, man-made detergents and chemicals; problems associated with chronic occupational skin exposure to toxic chemicals; animal alternative research programmes; carcinogenic and Photo Carcinogenic Potential Of Xenobiotic Chemicals; Oculotoxicity; Risk assessment and management; and cosmetic safety. Anatomical factors affecting barrier functions/ lipids of the permeability barrier/the skin immune system.

Author: Patricia K. Farris
Publisher: John Wiley & Sons
ISBN: 1118384806
Category : Medical
Languages : en
Pages : 309

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Book Description
Provide expert advice on cosmeceuticals and integrate them into your cosmetic practice Patients look to you for expert advice on topical skin care product, and cosmeceuticals are an important innovation. They want to know which products will work best for them. But new products seem to appear almost daily. How can you provide your patients with effective advice on how and when to use cosmeceuticals? In Cosmeceuticals and Cosmetic Practice, Dr Farris has invited leading experts, including cosmetic chemists, researchers and cosmetic dermatologists, to provide these answers. Together they have analysed and synthesized the evidence and combined it with their experience to provide you with best-practice advice on the most effective way to apply cosmeceuticals in your everyday practice. This book explains: • How cosmeceutical products are developed, tested and how they work • The most up-to-date key ingredients such as: Vitamin antioxidants Botanicals Peptides Growth factors Stem cells • How to use cosmeceuticals in practice Cosmeceuticals and Cosmetic Practice shows you how to improve the health and appearance of your patients’ skin. Titles of related interest Dermatologic Surgery: Step by Step Nouri (ed.); ISBN 978-1-4443-3067-0 Ethnic Dermatology: Principles and Practice Dadize, Petit, Alexis (eds); ISBN 978-0-470-65857-4 Diagnostic Dermoscopy: The Illustrated Guide Bowling; ISBN 978-1-4051-9855-4

Author: Zoe Diana Draelos
Publisher: CRC Press
ISBN: 1841847410
Category : Medical
Languages : en
Pages : 280

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Book Description
Cosmetics for skin, hair, and nails play a vital part in the management and treatment of many dermatological conditions; unfortunately, they may also at times be the cause of some dermatological problems. They are therefore subjects where dermatologists need to be aware of the major commercial developments taking place, in addition to the many common Over The Counter products already available, in order to be vigilant in checking the possible benefits or disadvantages for patients. This text takes a serious look at the integration of skin care products, cosmetics, hair adornments, and nail cosmetics in the daily practice of dermatology, expanding the realm of disease treatment beyond diagnosis and treatment into the maintenance phase of healthy skin, hair, and nails.