Author: Barry M. Trost
Publisher: Elsevier
ISBN: 0080912443
Category : Science
Languages : en
Pages : 1012
Book Description
Volume 1 provides a detailed survey of reactions that entail the 1,2-addition of nonstabilized carbanion equivalents of carbonyl, imino and thiocarbonyl functionality. Emphasis has been placed on those reagents that result in highly selective addition reactions. Methods are reported to select, for example, one carbonyl group over another in the same molecule, or to add preferentially a fragment to one (enantiotopic of diastereotopic) face of a carbonyl group. Processes that result from an initial addition to the C=X functional group, for example alkenations and rearrangements, are also covered in this volume.
Additions to C-X ?-Bonds
Author: Barry M. Trost
Publisher: Elsevier
ISBN: 0080912443
Category : Science
Languages : en
Pages : 1012
Book Description
Volume 1 provides a detailed survey of reactions that entail the 1,2-addition of nonstabilized carbanion equivalents of carbonyl, imino and thiocarbonyl functionality. Emphasis has been placed on those reagents that result in highly selective addition reactions. Methods are reported to select, for example, one carbonyl group over another in the same molecule, or to add preferentially a fragment to one (enantiotopic of diastereotopic) face of a carbonyl group. Processes that result from an initial addition to the C=X functional group, for example alkenations and rearrangements, are also covered in this volume.
Publisher: Elsevier
ISBN: 0080912443
Category : Science
Languages : en
Pages : 1012
Book Description
Volume 1 provides a detailed survey of reactions that entail the 1,2-addition of nonstabilized carbanion equivalents of carbonyl, imino and thiocarbonyl functionality. Emphasis has been placed on those reagents that result in highly selective addition reactions. Methods are reported to select, for example, one carbonyl group over another in the same molecule, or to add preferentially a fragment to one (enantiotopic of diastereotopic) face of a carbonyl group. Processes that result from an initial addition to the C=X functional group, for example alkenations and rearrangements, are also covered in this volume.
Comprehensive Organic Synthesis: Additions to and substitutions at C-C[pi]-Bonds
Author: Barry M. Trost
Publisher: Elsevier
ISBN: 9780080405957
Category : Science
Languages : en
Pages : 1328
Book Description
Volume 4 focuses on additions and the resulting substitutions at carbon-carbon &pgr;-bonds. Part 1 includes processes generally considered as simple polar reactions, reactive electrophiles and nucleophiles adding to alkenes and alkynes. A major topic is Michael-type addition to electron deficient &pgr;-bonds, featured in the first six chapters. In part 2 are collected the four general processes leading to nucleophilic aromatic substitution, including radical chain processes and transition metal activation through to &pgr;-complexation. Metal-activated addition (generally by nucleophiles) to alkenes and polyenes is presented in part 3, including allylic alkylation catalyzed by palladium. The coverage of nonpolar additions in part 4 includes radical additions, organometal addition (Heck reaction), carbene addition, and 1,3-dipolar cycloadditions.
Publisher: Elsevier
ISBN: 9780080405957
Category : Science
Languages : en
Pages : 1328
Book Description
Volume 4 focuses on additions and the resulting substitutions at carbon-carbon &pgr;-bonds. Part 1 includes processes generally considered as simple polar reactions, reactive electrophiles and nucleophiles adding to alkenes and alkynes. A major topic is Michael-type addition to electron deficient &pgr;-bonds, featured in the first six chapters. In part 2 are collected the four general processes leading to nucleophilic aromatic substitution, including radical chain processes and transition metal activation through to &pgr;-complexation. Metal-activated addition (generally by nucleophiles) to alkenes and polyenes is presented in part 3, including allylic alkylation catalyzed by palladium. The coverage of nonpolar additions in part 4 includes radical additions, organometal addition (Heck reaction), carbene addition, and 1,3-dipolar cycloadditions.
Additions to and Substitutions at C-C ?-Bonds
Author: M.F. Semmelhack
Publisher: Elsevier
ISBN: 0080912478
Category : Science
Languages : en
Pages : 1322
Book Description
Volume 4 focuses on additions and the resulting substitutions at carbon-carbon &pgr;-bonds. Part 1 includes processes generally considered as simple polar reactions, reactive electrophiles and nucleophiles adding to alkenes and alkynes. A major topic is Michael-type addition to electron deficient &pgr;-bonds, featured in the first six chapters. In part 2 are collected the four general processes leading to nucleophilic aromatic substitution, including radical chain processes and transition metal activation through to &pgr;-complexation. Metal-activated addition (generally by nucleophiles) to alkenes and polyenes is presented in part 3, including allylic alkylation catalyzed by palladium. The coverage of nonpolar additions in part 4 includes radical additions, organometal addition (Heck reaction), carbene addition, and 1,3-dipolar cycloadditions.
Publisher: Elsevier
ISBN: 0080912478
Category : Science
Languages : en
Pages : 1322
Book Description
Volume 4 focuses on additions and the resulting substitutions at carbon-carbon &pgr;-bonds. Part 1 includes processes generally considered as simple polar reactions, reactive electrophiles and nucleophiles adding to alkenes and alkynes. A major topic is Michael-type addition to electron deficient &pgr;-bonds, featured in the first six chapters. In part 2 are collected the four general processes leading to nucleophilic aromatic substitution, including radical chain processes and transition metal activation through to &pgr;-complexation. Metal-activated addition (generally by nucleophiles) to alkenes and polyenes is presented in part 3, including allylic alkylation catalyzed by palladium. The coverage of nonpolar additions in part 4 includes radical additions, organometal addition (Heck reaction), carbene addition, and 1,3-dipolar cycloadditions.
Combining C-C ?-Bonds
Author: L.A. Paquette
Publisher: Elsevier
ISBN: 0080912486
Category : Science
Languages : en
Pages : 1360
Book Description
The guiding principle underlying the subject matter specifically compiled in Volume 5 has been to make available to the organic chemical community a sourcebook comprehensively covering all the important &pgr;-bond-dependent transformations. Thermal, photochemical, and metal-catalyzed cycloadditions of every major type are expertly detailed by the most knowledgeable researchers in these areas. The synthetically useful electrocyclic and sigmatropic processes where alkenic centers are intimately involved in the structural change are similarly canvassed in compact detail. With added attention given to ene reactions, small-ring rearrangements, and related transition metal-associated reactions, coverage has been achieved of the full range of organic transformations directly involving the rebonding of alkenic centers. As a consequence, this volume should serve as the comprehensive sourcebook of the field for the next decade and beyond.
Publisher: Elsevier
ISBN: 0080912486
Category : Science
Languages : en
Pages : 1360
Book Description
The guiding principle underlying the subject matter specifically compiled in Volume 5 has been to make available to the organic chemical community a sourcebook comprehensively covering all the important &pgr;-bond-dependent transformations. Thermal, photochemical, and metal-catalyzed cycloadditions of every major type are expertly detailed by the most knowledgeable researchers in these areas. The synthetically useful electrocyclic and sigmatropic processes where alkenic centers are intimately involved in the structural change are similarly canvassed in compact detail. With added attention given to ene reactions, small-ring rearrangements, and related transition metal-associated reactions, coverage has been achieved of the full range of organic transformations directly involving the rebonding of alkenic centers. As a consequence, this volume should serve as the comprehensive sourcebook of the field for the next decade and beyond.
Comprehensive Organic Synthesis
Author: B. M. Trost
Publisher: Pergamon
ISBN: 9780080359298
Category : Science
Languages : en
Pages : 10400
Book Description
The development of more effective routes to known materials and the production of new materials are important goals in many areas, including electronics, agriculture, medicine and textiles. Organic synthesis is central to achieving these goals. Comprehensive Organic Synthesisdraws together the common themes that underlie the many apparently disparate areas of organic chemistry which underpin synthetic strategies, thus providing a comprehensive overview of this important discipline. The contributions have been organized to reflect the way in which synthetic chemists approach a problem. In terms of organic molecules, the work is divided into formation of carbon-carbon bonds, introduction of heteroatoms and heteroatom interconversions. Thus, Volumes 1-5 focus on carbon-carbon formation, but also include aspects of heteroatom introduction. Volumes 6-8 concentrate on interconversion of heteroatoms, but also deal with exchange of carbon-carbon bonds for carbon-heteroatom bonds. Organization of the chapters is along the theme of selectivity, which is a critical question in determining the suitability of a synthetic method. Volume 9 contains cumulative author and subject indexes. Comprehensive Organic Synthesis will appeal to a wide audience. The set will be an essential reference work for all those seeking information on the solution of synthetic problems, whether they be experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis an invaluable source, providing authoritative accounts of the essential facts and concepts.
Publisher: Pergamon
ISBN: 9780080359298
Category : Science
Languages : en
Pages : 10400
Book Description
The development of more effective routes to known materials and the production of new materials are important goals in many areas, including electronics, agriculture, medicine and textiles. Organic synthesis is central to achieving these goals. Comprehensive Organic Synthesisdraws together the common themes that underlie the many apparently disparate areas of organic chemistry which underpin synthetic strategies, thus providing a comprehensive overview of this important discipline. The contributions have been organized to reflect the way in which synthetic chemists approach a problem. In terms of organic molecules, the work is divided into formation of carbon-carbon bonds, introduction of heteroatoms and heteroatom interconversions. Thus, Volumes 1-5 focus on carbon-carbon formation, but also include aspects of heteroatom introduction. Volumes 6-8 concentrate on interconversion of heteroatoms, but also deal with exchange of carbon-carbon bonds for carbon-heteroatom bonds. Organization of the chapters is along the theme of selectivity, which is a critical question in determining the suitability of a synthetic method. Volume 9 contains cumulative author and subject indexes. Comprehensive Organic Synthesis will appeal to a wide audience. The set will be an essential reference work for all those seeking information on the solution of synthetic problems, whether they be experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis an invaluable source, providing authoritative accounts of the essential facts and concepts.
Comprehensive Organic Synthesis
Author: B. M. Trost
Publisher: Pergamon
ISBN: 9780080359298
Category : Science
Languages : en
Pages : 0
Book Description
The development of more effective routes to known materials and the production of new materials are important goals in many areas, including electronics, agriculture, medicine and textiles. Organic synthesis is central to achieving these goals. Comprehensive Organic Synthesisdraws together the common themes that underlie the many apparently disparate areas of organic chemistry which underpin synthetic strategies, thus providing a comprehensive overview of this important discipline. The contributions have been organized to reflect the way in which synthetic chemists approach a problem. In terms of organic molecules, the work is divided into formation of carbon-carbon bonds, introduction of heteroatoms and heteroatom interconversions. Thus, Volumes 1-5 focus on carbon-carbon formation, but also include aspects of heteroatom introduction. Volumes 6-8 concentrate on interconversion of heteroatoms, but also deal with exchange of carbon-carbon bonds for carbon-heteroatom bonds. Organization of the chapters is along the theme of selectivity, which is a critical question in determining the suitability of a synthetic method. Volume 9 contains cumulative author and subject indexes. Comprehensive Organic Synthesis will appeal to a wide audience. The set will be an essential reference work for all those seeking information on the solution of synthetic problems, whether they be experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis an invaluable source, providing authoritative accounts of the essential facts and concepts.
Publisher: Pergamon
ISBN: 9780080359298
Category : Science
Languages : en
Pages : 0
Book Description
The development of more effective routes to known materials and the production of new materials are important goals in many areas, including electronics, agriculture, medicine and textiles. Organic synthesis is central to achieving these goals. Comprehensive Organic Synthesisdraws together the common themes that underlie the many apparently disparate areas of organic chemistry which underpin synthetic strategies, thus providing a comprehensive overview of this important discipline. The contributions have been organized to reflect the way in which synthetic chemists approach a problem. In terms of organic molecules, the work is divided into formation of carbon-carbon bonds, introduction of heteroatoms and heteroatom interconversions. Thus, Volumes 1-5 focus on carbon-carbon formation, but also include aspects of heteroatom introduction. Volumes 6-8 concentrate on interconversion of heteroatoms, but also deal with exchange of carbon-carbon bonds for carbon-heteroatom bonds. Organization of the chapters is along the theme of selectivity, which is a critical question in determining the suitability of a synthetic method. Volume 9 contains cumulative author and subject indexes. Comprehensive Organic Synthesis will appeal to a wide audience. The set will be an essential reference work for all those seeking information on the solution of synthetic problems, whether they be experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis an invaluable source, providing authoritative accounts of the essential facts and concepts.
Comprehensive Organic Functional Group Transformations: Synthesis: carbon with two heteroatoms, each attached by a single bond
Radicals in Organic Synthesis
Author: Bernd Giese
Publisher: C R C Press Reprints
ISBN:
Category : Science
Languages : en
Pages : 316
Book Description
Publisher: C R C Press Reprints
ISBN:
Category : Science
Languages : en
Pages : 316
Book Description
Comprehensive Organic Transformations
Author: Richard C. Larock
Publisher: Wiley-VCH
ISBN: 9781118037607
Category : Science
Languages : en
Pages : 0
Book Description
This long-awaited, greatly-expanded new edition of a best-selling guide offers an encyclopedic and systematic collection of useful synthetic methodology, including tens of thousands of reactions and synthetic transformations. The first edition has been reviewed in the professional journals as clearly...the first choice for researchers seeking information on synthetic transformations. And as useful to anyone who must do organic synthesis, especially those whose focus is not strictly organic chemistry. It provides a...clear road map to the synthetic literature and should be kept within easy reach of the chemist's desk.
Publisher: Wiley-VCH
ISBN: 9781118037607
Category : Science
Languages : en
Pages : 0
Book Description
This long-awaited, greatly-expanded new edition of a best-selling guide offers an encyclopedic and systematic collection of useful synthetic methodology, including tens of thousands of reactions and synthetic transformations. The first edition has been reviewed in the professional journals as clearly...the first choice for researchers seeking information on synthetic transformations. And as useful to anyone who must do organic synthesis, especially those whose focus is not strictly organic chemistry. It provides a...clear road map to the synthetic literature and should be kept within easy reach of the chemist's desk.