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Author: Gunnar Samuelsson Publisher: Swedish Pharmaceutical Press ISBN: 9789198094251 Category : Natural products Languages : en Pages : 0
Book Description
Drugs of Natural Origin is a unique multidisciplinary book suitable for undergraduate and graduate students and teachers in the area of natural product science, but also as a complementary book for disciplines like medicinal chemistry, biochemistry and pharmacology. The book can also serve society as a scientific source for the understanding of a sustainable use of natural products in the development of new drugs, scientifically based herbal remedies, and environmentally friendly biomolecules. During evolution, molecules have been developed for specific functions in nature. These bioactive substances have a potential as new drug candidates in drug development, but also as pharmacological tools, intermediates or templates for synthesis of drugs. This book deals with terrestrial and marine bioactive substances of plant, microbial or animal origin. The occurrence, biosynthesis, isolation, chemistry and medical use are described together with basic research strategies. An increased understanding of the medical importance of bioactive natural products has developed in society. Since the publication of the sixth edition, six years ago, considerable progress has been achieved in the study of biosynthetic pathways, mainly based on gene technology. The revolution in high-throughput sequencing technology has given an increasing access to microbial genome sequences, which opens up new possibilities in the discovery of novel bioactive natural products. This development is reflected in a substantial revision and expansion of the book, but also removal of some sections containing products remotely associated with drugs. The new book also contains description of novel drugs marketed since the publication of the previous edition, especially in the field of diabetes, cancer and infection.
Author: Gunnar Samuelsson Publisher: Swedish Pharmaceutical Press ISBN: 9789198094251 Category : Natural products Languages : en Pages : 0
Book Description
Drugs of Natural Origin is a unique multidisciplinary book suitable for undergraduate and graduate students and teachers in the area of natural product science, but also as a complementary book for disciplines like medicinal chemistry, biochemistry and pharmacology. The book can also serve society as a scientific source for the understanding of a sustainable use of natural products in the development of new drugs, scientifically based herbal remedies, and environmentally friendly biomolecules. During evolution, molecules have been developed for specific functions in nature. These bioactive substances have a potential as new drug candidates in drug development, but also as pharmacological tools, intermediates or templates for synthesis of drugs. This book deals with terrestrial and marine bioactive substances of plant, microbial or animal origin. The occurrence, biosynthesis, isolation, chemistry and medical use are described together with basic research strategies. An increased understanding of the medical importance of bioactive natural products has developed in society. Since the publication of the sixth edition, six years ago, considerable progress has been achieved in the study of biosynthetic pathways, mainly based on gene technology. The revolution in high-throughput sequencing technology has given an increasing access to microbial genome sequences, which opens up new possibilities in the discovery of novel bioactive natural products. This development is reflected in a substantial revision and expansion of the book, but also removal of some sections containing products remotely associated with drugs. The new book also contains description of novel drugs marketed since the publication of the previous edition, especially in the field of diabetes, cancer and infection.
Author: Anthony Artuso Publisher: Psychology Press ISBN: 9780789001238 Category : Biodiversity conservation Languages : en Pages : 220
Book Description
Drugs of Natural Origin gives you a detailed model of the value of wild biological resources for pharmaceutical research and development. Author Anthony Artuso presents several decision models and analytical techniques that you can use to asses the economics of biochemical prospecting efforts whether you're part of a private corporation, nonprofit research institute, developing country government, or international organization.
Author: Gunnar Samuelsson Publisher: Swedish Pharmaceutical Press ISBN: 9781439838570 Category : Science Languages : en Pages : 0
Book Description
Drugs of Natural Origin provides a multidisciplinary approach suitable for those working in the area of natural product development. It brings together research on the sustainable use of natural products in the development of new drugs, scientifically based herbal remedies, and environmentally adapted biomolecules. During evolution, molecules evolved to perform specific functions in nature. By understanding their natural function, we can develop ways to make use of these bioactive substances a potential new drug candidates and also as pharmacological tools, intermediates, or templates for the synthesis of novel drugs. This book examines terrestrial and marine bioactive substances drawn from plant, microbial, and animal origin. Their occurrence, biosynthesis, isolation, chemistry, and medical use are described, together with basic research strategies. Development in the field of natural products of medical importance continues to expand. Since the publication of the 5th edition of this book, five years ago, new concepts such as chemo- and bioinformatics, phylogenetics and systems biology with the new ”omics” techniques (genomics, proteomics and metabolomics) have emerged. Herbal remedies have become subject to more rigid legislation aiming to improve their quality and efficacy, both as over-the-counter preparations for self-medication and as constituents of conventional drugs. This development is reflected in a substantial revision and expansion of the book. This edition also describes many new drugs marketed since the publication of the previous edition. Students and professors in the area of natural product research,as well as complementary disciplines like medicinal chemistry, biochemistry, and pharmacology will find much relevant information in this books.
Author: Anthony Artuso Publisher: Routledge ISBN: 1135408947 Category : Health & Fitness Languages : en Pages : 210
Book Description
Despite the growing interest in biodiversity as a source of valuable new products and biochemical information, there have been very few systematic efforts to estimate the value of preserving biological resources for this purpose. Drugs of Natural Origin gives you a detailed model of the value of wild biological resources for pharmaceutical research and development. Author Anthony Artuso presents several decision models and analytical techniques that you can use to assess the economics of biochemical prospecting efforts whether you’re part of a private corporation, nonprofit research institute, developing country government, or international organization. Drugs of Natural Origin explores the policy options available to developing countries and international organizations to tap into the emerging market for biological resources in such a way as to provide both incentives for conservation of biodiversity and new opportunities for economic development. You’ll find evaluations of a range of proactive strategies that can be used to protect and enhance developing countries’biological resources. In addition, you’ll learn about a bioeconomic model that incorporates the potential biochemical and genetic value of a diverse ecosystem into land use planning and development. Developing country and international policymakers will find Drugs of Natural Origin a useful tool for determining how best to conserve biodiversity, while sustainably developing biological resources. This book outlines a comprehensive and integrated set of policy measures, research and development initiatives, and financing arrangements that could increase biochemical research activity while providing incentives for conservation of biodiversity and a potential path for sustainable development. Managers of pharmaceutical R&D programs will use the decision models developed in Drugs of Natural Origin to plan, evaluate, and continually refine their R&D programs. The book’s theoretic framework provides you with an analytical tool for systematically evaluating critical decisions at each stage of the R&D process. Thus, you learn to incorporate both subjective assessments and quantitative data into a comprehensive framework for R&D decisionmaking.
Author: Iris F. F. Benzie Publisher: CRC Press ISBN: 1439807167 Category : Health & Fitness Languages : en Pages : 500
Book Description
The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef
Author: Guan-Hua Du Publisher: Springer ISBN: 9811080224 Category : Medical Languages : en Pages : 741
Book Description
This book discusses 120 types of natural, small-molecule drugs derived from plants. They are grouped into 7 parts according their clinical uses, such as drugs for cardiovascular diseases, for metabolic diseases, for neuropsychiatric diseases, for immune-mediated inflammatory diseases, anti-tumor drugs, and drugs for parasites and bacterial infection. Each chapter systematically summarizes one drug, including its physicochemical properties, sources, pharmacological effects and clinical applications. To help readers understand the drug better, the research and pharmacological activity for each drug is also described, which serves as a salutary lesson for future drug development. Written by frontline researchers, teachers and clinicians working in field of pharmacy and pharmacology it provides an overview of natural, small-molecule drugs derived from plants for researchers in the field.
Author: Rohit Dutt Publisher: Apple Academic Press ISBN: 9781003010395 Category : Science Languages : en Pages : 458
Book Description
"This new volume, Promising Drug Molecules of Natural Origin, explores potential beneficial drug substances derived from nature. It presents the general principles, characteristics, evaluation techniques, and applications involved in drug molecules from natural sources, such as plants and marine life. With chapters from renowned experts from around the world, the chapters in this volume address the challenges of standardization of herbal medicines, methods of characterization of natural medicines and phyto-constituents, and quality control methods for herbal medicines. Several chapters in the book focus on the evolution of phyto-constituents in cancer therapeutics, while others deal with applications for other diseases, such as diabetes and neuroinflammatory disorders. The volume also specifically reviews heterocyclic drugs from plants. Key features: Provides an exhaustive overview of drugs originating from nature Covers scientific study protocols for characterization Presents diverse applications and uses for herbal medicines Looks at the use of herbal medicines for specific diseases and health conditions, such as diabetes and neuroinflammatory disorders This volume will be a valuable resource for faculty and advanced students in pharmaceutics as well as researchers, scientists, and industry professionals in medicine and drug development"--
Author: Iqbal Ahmad Publisher: John Wiley & Sons ISBN: 3527609539 Category : Medical Languages : en Pages : 404
Book Description
This timely and original handbook paves the way to success in plant-based drug development, systematically addressing the issues facing a pharmaceutical scientist who wants to turn a plant compound into a safe and effective drug. Plant pharmacologists from around the world demonstrate the potentials and pitfalls involved, with many of the studies and experiments reported here published for the first time. The result is a valuable source of information unavailable elsewhere.
Author: Ashish Tewari Publisher: Elsevier ISBN: 0081022743 Category : Science Languages : en Pages : 368
Book Description
Synthesis of Medicinal Agents from Plants highlights the importance of synthesizing medicinal agents from plants and outlines methods for performing it effectively. Beginning with an introduction to the significance of medicinal plants, the book goes on to provide a historical overview of drug synthesis before exploring how this can be used to successfully replicate and adapt the active agents from natural sources. Chapters then explore the medicinal properties of a number of important plants, before concluding with a discussion of the future of drugs from medicinal plants. Illustrated with real-world examples, it is a practical resource for researchers in this field. In an age of rapid environmental destruction, hundreds of medicinal plants are at risk of extinction from overexploitation and deforestation, limiting the natural resources available for active agent extraction, thereby threatening the discovery of future cures for diseases. Simultaneously, with the increasing population and advances in medical sciences, the demand for drugs is continuously increasing and cannot be met with just plants. The ability to synthetically replicate the active compounds from these plants is essential in creating an ecologically-aware, sustainable future for drug design Includes detailed coverage of therapeutic compound synthesis Uses multiple real-world examples to support content Lays out a sustainable template for the future of developing active agents from natural products
Author: Gunnar Samuelsson
Author: Gunnar Samuelsson
Author: Anthony Artuso
Author: Gunnar Samuelsson
Author: Gunnar Samuelsson
Author: Anthony Artuso
Author: Iris F. F. Benzie
Author: Guan-Hua Du
Author: Rohit Dutt
Author: Iqbal Ahmad
Author: Ashish Tewari