Epitope mapped vaccines and diagnostics for emerging pathogens PDF Download

Author: Tarek A. Ahmad
Publisher: Frontiers Media SA
ISBN: 2832513018
Category : Medical
Languages : en
Pages : 277

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Book Description

Author: Christian Schönbach
Publisher: Springer Science & Business Media
ISBN: 0387729682
Category : Medical
Languages : en
Pages : 216

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Book Description
In contrast to existing books on immunoinformatics, this volume presents a cross-section of immunoinformatics research. The contributions highlight the interdisciplinary nature of the field and how collaborative efforts among bioinformaticians and bench scientists result in innovative strategies for understanding the immune system. Immunoinformatics is ideal for scientists and students in immunology, bioinformatics, microbiology, and many other disciplines.

Author: Ulrich Reineke
Publisher: Humana Press
ISBN: 9781934115176
Category : Science
Languages : en
Pages : 450

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Book Description
Given the versatile utility of the determinination of epitopes, beneficial to a wide variety of scientists from immunologists to structural biologists to biotechnologists, the need for a thorough, state-of-the-art collection of experimental protocols is clear. In Epitope Mapping Protocols, Second Edition, expert contributors from a broad spectrum of scientific backgrounds update and expand the successful first edition with cutting-edge techniques and applications, including approaches to both antibody or B-cell epitope mapping and T-cell epitope mapping as well as a new section on the profiling of antibody signatures in biological fluids. Written in the popular Methods in Molecular BiologyTM series format, chapters include brief introductions to the topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and Notes sections, which highlight tips on troubleshooting and avoiding known pitfalls. Comprehensive and up-to-date, Epitope Mapping Protocols, Second Edition is a reliable and valuable reference for all those who wish to understand and further investigate the diversifying field of epitope mapping.

Author: Rolf Hilgenfeld
Publisher: Springer
ISBN: 981108727X
Category : Medical
Languages : en
Pages : 375

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Book Description
This contributed volume contains 25 chapters from leading international scientists working on dengue and Zika viruses, who came together in Praia do Tofo in Mozambique to discuss the latest developments in the fields of epidemiology, pathogenesis, structural virology, immunology, antiviral drug discovery and development, vaccine efficacy, and mosquito control programs. The meeting venue offered an opportunity to discuss current research on these flaviviruses in an idyllic setting, and also to develop first-hand appreciation of the issues in infectious diseases facing developing countries and of the research gaps in Africa. For readers, who should include basic and clinical researchers in the field and public health professionals, the chapters are organized to provide a comprehensive overview of the various topics in current dengue and Zika virus research. A unique feature of the proceedings of this meeting is the inclusion of the discussions that took place following presentations. These have been transcribed and appended to the end of the relevant chapters, and they form the “salt in the soup” of this book.

Author: Bhanu Chander
Publisher: CRC Press
ISBN: 1003836275
Category : Computers
Languages : en
Pages : 477

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Book Description
This handbook provides thorough, in-depth, and well-focused developments of artificial intelligence (AI), machine learning (ML), deep learning (DL), natural language processing (NLP), cryptography, and blockchain approaches, along with their applications focused on healthcare systems. Handbook of AI-Based Models in Healthcare and Medicine: Approaches, Theories, and Applications highlights different approaches, theories, and applications of intelligent systems from a practical as well as a theoretical view of the healthcare domain. It uses a medically oriented approach in its discussions of human biology, healthcare, and medicine and presents NLP-based medical reports and medicine enhancements. The handbook includes advanced models of ML and DL for the management of healthcare systems and also discusses blockchain-based healthcare management. In addition, the handbook offers use cases where AI, ML, and DL can help solve healthcare complications. Undergraduate and postgraduate students, academicians, researchers, and industry professionals who have an interest in understanding the applications of ML/DL in the healthcare setting will want this reference on their bookshelf.

Author: Dean T. Jamison
Publisher: World Bank Publications
ISBN: 1464805288
Category : Medical
Languages : en
Pages : 426

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Book Description
As the culminating volume in the DCP3 series, volume 9 will provide an overview of DCP3 findings and methods, a summary of messages and substantive lessons to be taken from DCP3, and a further discussion of cross-cutting and synthesizing topics across the first eight volumes. The introductory chapters (1-3) in this volume take as their starting point the elements of the Essential Packages presented in the overview chapters of each volume. First, the chapter on intersectoral policy priorities for health includes fiscal and intersectoral policies and assembles a subset of the population policies and applies strict criteria for a low-income setting in order to propose a "highest-priority" essential package. Second, the chapter on packages of care and delivery platforms for universal health coverage (UHC) includes health sector interventions, primarily clinical and public health services, and uses the same approach to propose a highest priority package of interventions and policies that meet similar criteria, provides cost estimates, and describes a pathway to UHC.

Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309314003
Category : Medical
Languages : en
Pages : 336

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Book Description
In the past half century, deadly disease outbreaks caused by novel viruses of animal origin - Nipah virus in Malaysia, Hendra virus in Australia, Hantavirus in the United States, Ebola virus in Africa, along with HIV (human immunodeficiency virus), several influenza subtypes, and the SARS (sudden acute respiratory syndrome) and MERS (Middle East respiratory syndrome) coronaviruses - have underscored the urgency of understanding factors influencing viral disease emergence and spread. Emerging Viral Diseases is the summary of a public workshop hosted in March 2014 to examine factors driving the appearance, establishment, and spread of emerging, re-emerging and novel viral diseases; the global health and economic impacts of recently emerging and novel viral diseases in humans; and the scientific and policy approaches to improving domestic and international capacity to detect and respond to global outbreaks of infectious disease. This report is a record of the presentations and discussion of the event.

Author: Mahbuba Rahman
Publisher: Frontiers Media SA
ISBN: 2832548474
Category : Medical
Languages : en
Pages : 351

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Book Description
The Human body is a vast network of interacting genes, proteins, and metabolites. These components, which may be considered host factors, change under disease, treatment or healthy condition. While treatment of many diseases depends on therapeutic drugs, vaccines remain the most effective long-term public health intervention to prevent infectious diseases. To date, vaccines have been developed to treat entire populations with little provision for predisposing individual host factor differences. However, the use and application of vaccines is facing multiple challenges with increasing numbers of vaccine non-responders and vaccine-relapsed individuals. The cause of this complication is partially due to host-factors. Another challenge is the adverse effects of vaccines in patients with primary immunodeficiency or autoimmune diseases, as well as vaccine-waning immunity in ageing populations, obese populations, or those with co-infection. To overcome these challenges, the solution may be the design, and formulation of precision vaccines, which are patient-specific.

Author: Perambur S Neelakanta
Publisher: World Scientific
ISBN: 9811212902
Category : Science
Languages : en
Pages : 684

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Book Description
This book on bioinformatics is designed as an introduction to the conventional details of genomics and proteomics as well as a practical comprehension text with an extended scope on the state-of-the-art bioinformatic details pertinent to next-generation sequencing, translational/clinical bioinformatics and vaccine-design related viral informatics.It includes four major sections: (i) An introduction to bioinformatics with a focus on the fundamentals of information-theory applied to biology/microbiology, with notes on bioinformatic resources, data bases, information networking and tools; (ii) a collection of annotations on the analytics of biomolecular sequences, with pertinent details presented on biomolecular informatics, pairwise and multiple sequences, viral sequence informatics, next-generation sequencing and translational/clinical bioinformatics; (iii) a novel section on cytogenetic and organelle bioinformatics explaining the entropy-theoretics of cellular structures and the underlying informatics of synteny correlations; and (iv) a comprehensive presentation on phylogeny and species informatics.The book is aimed at students, faculty and researchers in biology, health/medical sciences, veterinary/agricultural sciences, bioengineering, biotechnology and genetic engineering. It will be a useful companion for managerial personnel in the biotechnology and bioengineering industries as well as in health/medical science.

Author: Kayvon Modjarrad
Publisher: Academic Press
ISBN: 0128025425
Category : Medical
Languages : en
Pages : 186

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Book Description
Human Vaccines: Emerging Technologies in Design and Development discusses the advances in molecular biology, biophysics, and informatics—among other disciplines—that have provided scientists with the tools to create new vaccines against emerging and re-emerging pathogens. For example, the virus-like particle technologies that led to licensing of highly efficacious HPV vaccines have only come into full realization in the last 10 years. Their success has, in turn, accelerated the pace with which nanoparticle vaccines are being developed Given the rapidity with which the field is changing and the absence of any text documenting this change, there is a need for a resource that surveys these new vaccine technologies, assesses their potential, and describes their applications. This book provides that resource and complements traditional vaccinology books, but also serves as an excellent standalone for researchers and students with basic knowledge in immunology. Introduces new topics in vaccine immunology in the context vaccine design and production Consolidates the growing body of knowledge on new vaccine technologies that have only emerged in the past 2 – 3 decades Reviews the currently licensed vaccines that have utilized leading-edge technologies and how this has translated into improved efficacy and safety Provides a broad overview of innovative vaccine technologies, including immunological aspects