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Author: Bi-Cheng Liu Publisher: Springer ISBN: 9811388717 Category : Science Languages : en Pages : 709
Book Description
This book systemically presents the latest research on renal fibrosis, covering all the major topics in the field, including the possible mechanisms, biomarkers, and strategies for prevention and treatment of chronic kidney disease (CKD). Due to its high prevalence, CKD represents a huge global economic and social burden. Irrespective of the initial causes, CKD progresses to end stage kidney disease (ESKD) due to renal fibrosis, which is characterized by glomerulosclerosis, tubule atrophy and atresia, and the excessive accumulation of extracellular matrix (ECM) in the kidney. Unfortunately, an estimated 1%-2% of the adult population living with CKD will need renal replacement therapy at some point as a result of ESKD. As such, strategies for preventing or slowing CKD progression to ESKD are of utmost importance, and studies aiming to understand the mechanisms of renal fibrosis have been the focus of intensive research. Recently, novel insights into the pathophysiological processes have furthered our understanding of the pathogenesis of renal fibrosis, and more importantly, promoted studies on the early diagnosis and treatment of CKD. This book draws lessons from the extensive, state-of-the-art research in this field, elaborating the new theories and new techniques to offer readers a detailed and comprehensive understanding of renal fibrosis and as well as inspiration for future research directions.
Author: Bi-Cheng Liu Publisher: Springer ISBN: 9811388717 Category : Science Languages : en Pages : 709
Book Description
This book systemically presents the latest research on renal fibrosis, covering all the major topics in the field, including the possible mechanisms, biomarkers, and strategies for prevention and treatment of chronic kidney disease (CKD). Due to its high prevalence, CKD represents a huge global economic and social burden. Irrespective of the initial causes, CKD progresses to end stage kidney disease (ESKD) due to renal fibrosis, which is characterized by glomerulosclerosis, tubule atrophy and atresia, and the excessive accumulation of extracellular matrix (ECM) in the kidney. Unfortunately, an estimated 1%-2% of the adult population living with CKD will need renal replacement therapy at some point as a result of ESKD. As such, strategies for preventing or slowing CKD progression to ESKD are of utmost importance, and studies aiming to understand the mechanisms of renal fibrosis have been the focus of intensive research. Recently, novel insights into the pathophysiological processes have furthered our understanding of the pathogenesis of renal fibrosis, and more importantly, promoted studies on the early diagnosis and treatment of CKD. This book draws lessons from the extensive, state-of-the-art research in this field, elaborating the new theories and new techniques to offer readers a detailed and comprehensive understanding of renal fibrosis and as well as inspiration for future research directions.
Author: Keith C. Meyer Publisher: Springer Science & Business Media ISBN: 1627036822 Category : Medical Languages : en Pages : 457
Book Description
Idiopathic Pulmonary Fibrosis: A Comprehensive Clinical Guide delivers a concise review of our current understanding of disease pathogenesis and provides current evidence in the medical literature regarding its diagnosis and management. Each chapter includes key points and a summary aiming to update clinicians about various issues concerning the diagnosis and management of IPF. In addition to outlining the current state of knowledge, each chapter also provides a summary of ongoing research and identifies the needs for future research in the field. Idiopathic Pulmonary Fibrosis: A Comprehensive Clinical Guide is an important new text that provides its readers with a better understanding of the pathobiology and natural history of IPF as it continues to evolve.
Author: Ulrich Costabel Publisher: European Respiratory Society ISBN: 1849840687 Category : Medical Languages : en Pages : 287
Book Description
Idiopathic pulmonary fibrosis (IPF) is a steadily progressive and ultimately fatal disease of unknown origin. Recent years have seen advances in our understanding of IPF and a number of guidelines have been published. But many questions remain unanswered, particularly surrounding probable versus definite IPF. This Monograph aims to discuss the latest achievements in IPF, and covers key diagnostic issues, staging of the disease, complications and comorbidities, treatment, unmet patient needs and perspectives for the future. This book will be of interest to all clinicians and researchers in this area.
Author: Andrew Bush Publisher: CRC Press ISBN: 1444180010 Category : Medical Languages : en Pages : 699
Book Description
Hodson and Geddes' Cystic Fibrosis provides everything the respiratory clinician, pulmonologist or health professional treating patients needs in a single manageable volume. This international and authoritative work brings together current knowledge and has become established in previous editions as a leading reference in the field. This fourth edition includes a wealth of new information, figures, useful videos, and a companion eBook. The basic science that underlies the disease and its progression is outlined in detail and put into a clinical context. Diagnostic and clinical aspects are covered in depth, as well as promising advances such as gene therapies and other novel molecular based treatments. Patient monitoring and the importance of multidisciplinary care are also emphasized. This edition: Features accessible sections reflecting the multidisciplinary nature of the cystic fibrosis care team Contains a chapter written by patients and families about their experiences with the disease Includes expanded coverage of clinical areas, including chapters covering sleep, lung mechanics and the work of breathing, upper airway disease, insulin deficiency and diabetes, bone disease, and sexual and reproductive issues Discusses management both in the hospital and at home Includes a new section on monitoring and discusses the use of databases to improve patient care Covers monitoring in different age groups, exercise testing and the outcomes of clinical trials in these areas Includes chapters devoted to nursing, physiotherapy, psychology, and palliative and spiritual care Throughout, the emphasis is on providing an up-to-date and balanced review of both the clinical and basic science aspects of the subject and reflecting the multidisciplinary nature of the cystic fibrosis care team.
Author: David M. Orenstein Publisher: Lippincott Williams & Wilkins ISBN: 1451154380 Category : Medical Languages : en Pages : 788
Book Description
This one-of-a-kind guide offers easy-to-understand explanations, advice, and management options for patients or parents of patients with cystic fibrosis. The book explains the disease process, outlines the fundamentals of diagnosing and screening, and addresses the challenges of treatment for those living with CF. As one reviewer said, this book “is the only complete answer book for everyone living with the disease. It is an indispensable resource for families of children with CF, adolescent and adult patients, and physicians, nurses, respiratory therapists, and social workers involved in the care of CF patients.”
Author: Andrew Bush Publisher: Karger Medical and Scientific Publishers ISBN: 3805579608 Category : Medical Languages : en Pages : 341
Book Description
Cystic fibrosis used to be thought of as a respiratory and digestive disease, with a uniformly and rapidly fatal outcome. The spectrum of the disease has broadened into the mild atypical case, presenting in middle age, with the potential for complications in virtually every system of the body. In the past few years there has been an explosion of knowledge of the basic science of the defect. The editors have therefore invited the leading scientists and clinicians in the field of cystic fibrosis to describe the recent advances in this disease. Although there are many 'Recent Advances' texts, previous books have been selective in their choice of topics. This book is the first to cover the entire field of this complex disease, and encompasses the rapidly moving topics of the basic molecular and cellular biology as well as the recent multi-system, multi-disciplinary advances in the clinical care of patients. The authors have been charged with writing only about new developments and not to rehash old literature. The bulk of the references is therefore less than five years old. This book addresses all professionals who treat cystic fibrosis and want to have an up-date of new findings in the field, particularly of those outside their immediate specialisation. It will also be useful for basic researchers interested in related scientific areas and the clinical context of their work.
Author: Jeffrey Swigris Publisher: Elsevier Health Sciences ISBN: 0323544320 Category : Medical Languages : en Pages : 350
Book Description
Designed with the practicing clinician in mind, Idiopathic Pulmonary Fibrosis provides a succinct, easy-to-digest overview of this challenging condition in which the cause of thickening lung tissue is unknown. This concise resource by Drs. Kevin K. Brown and Jeff Swigris provides essential information for the physician who sees pulmonary fibrosis patients, including epidemiology, genetics and biomarkers, pathology, diagnosis, disease monitoring, and therapeutics intended to improve the patient’s lifespan and quality of life.
Author: Joseph P. Lynch Publisher: CRC Press ISBN: 0203913442 Category : Medical Languages : en Pages : 800
Book Description
A discussion of the epidemiology, clinical features, and differential diagnoses of idiopathic pulmonary fibrosis (IPF). Key topics include the role of polymorphonuclear leukocytes in the pathogenesis of pulmonary fibrosis, and current treatment options, including medical therapy and lung transplantation.
Author: Giulio Gabbiani Publisher: Academic Press ISBN: 0323906591 Category : Medical Languages : en Pages : 134
Book Description
Wound Healing, and the Myofibroblast: A Historical and Biological Perspective is the fruit of an interdisciplinary and international collaboration involving a historian of medicine (Dr. Zampieri), a physician (Dr. Coen), and a researcher (Prof. Gabbiani, world-renowned for his discovery of the myofibroblast). This book aims to draw a concise yet complete description of the conceptual evolution of wound healing, fibrosis and fibrosis-related pathologies from antiquity to present time, as well as commenting on the role of the myofibroblast and the key cell type essential for tissue repair and fibrosis (from its identification in 1971 throughout its 50-years-old history). By viewing this complex and century-long history from different perspectives, the book's authors aim to draw an exhaustive overview, with the hope of inspiring new and fruitful basic and clinical research. Interdisciplinary collaboration: complementary views from medical historian, a physician and a researcher A concise but detailed history of fibrosis, readers can discover the major scientific breakthroughs along this history Includes the pathophysiology of various fibrotic diseases Explores the role of myofibroblast in fibrosis development