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Author: Anthony K. Campbell Publisher: John Wiley & Sons ISBN: 111894187X Category : Science Languages : en Pages : 466
Book Description
The definitive text on the key component for cell functions—intracellular calcium This comprehensive book reveals the evidence for intracellular calcium as a universal switch in all animal, plant, fungal and microbial cells. It shows how the components required for calcium signaling are named and classified; covers the technology that has been developed to study intracellular calcium; describes how calcium is regulated inside cells and how it works to trigger an event; explains the role of intracellular calcium in disease, cell injury, and cell death; reveals how many drugs work through the calcium signaling system; and demonstrates how intracellular calcium is involved in the action of many natural toxins. The book also illustrates how the intracellular calcium signaling system has evolved over millions of years, showing why it was crucial to the origin of life. Additionally, the book promotes the importance of the molecular variation upon which the intracellular calcium signalling system depends. Featuring more than 100 figures (including detailed chemical structures as well as pictures of key pioneers in the field), a bibliography of some 1000 references, and a detailed subject index, this definitive work provides a unique source of scholarship for teachers and researchers in the biomedical sciences and beyond. Emphasizes two key scientific principles—the first to show how intracellular Ca2+ acts as a switch, to activate a wide range of cellular events, and the second demonstrating how an analogue mechanism can be superimposed on such a process Written by an internationally recognized expert in the field Filled with images and references to facilitate learning Fundamentals of Intracellular Calcium is an all-important text for post-graduate students and researchers working in biomedicine and biochemistry. It is also essential for undergraduate lecturers and their students in physiology, medicine, pharmacy, and the biosciences.
Author: Anthony K. Campbell Publisher: John Wiley & Sons ISBN: 111894187X Category : Science Languages : en Pages : 466
Book Description
The definitive text on the key component for cell functions—intracellular calcium This comprehensive book reveals the evidence for intracellular calcium as a universal switch in all animal, plant, fungal and microbial cells. It shows how the components required for calcium signaling are named and classified; covers the technology that has been developed to study intracellular calcium; describes how calcium is regulated inside cells and how it works to trigger an event; explains the role of intracellular calcium in disease, cell injury, and cell death; reveals how many drugs work through the calcium signaling system; and demonstrates how intracellular calcium is involved in the action of many natural toxins. The book also illustrates how the intracellular calcium signaling system has evolved over millions of years, showing why it was crucial to the origin of life. Additionally, the book promotes the importance of the molecular variation upon which the intracellular calcium signalling system depends. Featuring more than 100 figures (including detailed chemical structures as well as pictures of key pioneers in the field), a bibliography of some 1000 references, and a detailed subject index, this definitive work provides a unique source of scholarship for teachers and researchers in the biomedical sciences and beyond. Emphasizes two key scientific principles—the first to show how intracellular Ca2+ acts as a switch, to activate a wide range of cellular events, and the second demonstrating how an analogue mechanism can be superimposed on such a process Written by an internationally recognized expert in the field Filled with images and references to facilitate learning Fundamentals of Intracellular Calcium is an all-important text for post-graduate students and researchers working in biomedicine and biochemistry. It is also essential for undergraduate lecturers and their students in physiology, medicine, pharmacy, and the biosciences.
Author: Claus W. Heizmann Publisher: Springer Science & Business Media ISBN: 364276150X Category : Science Languages : en Pages : 606
Book Description
A wide variety of hormones, neurotransmitters and growth factors exert their cellular effects by reacting first with membrane receptors resulting in an increase of intracellular calcium and the cellular response. The calcium signal in the cell is mediated by the high-affinity calcium binding proteins (characterized by the EF-hand structural element), and by the calcium and phospholipid dependent proteins. Many of these have been discovered most recently. Their purification, distribution, protein and gene structures as well as their physiological roles are discussed. The book is of interest to biochemists and molecular biologists as well as to clinicians and the pharmaceutical industry who can apply the results in this field.
Author: Alex Fornito Publisher: Academic Press ISBN: 0124081185 Category : Medical Languages : en Pages : 494
Book Description
Fundamentals of Brain Network Analysis is a comprehensive and accessible introduction to methods for unraveling the extraordinary complexity of neuronal connectivity. From the perspective of graph theory and network science, this book introduces, motivates and explains techniques for modeling brain networks as graphs of nodes connected by edges, and covers a diverse array of measures for quantifying their topological and spatial organization. It builds intuition for key concepts and methods by illustrating how they can be practically applied in diverse areas of neuroscience, ranging from the analysis of synaptic networks in the nematode worm to the characterization of large-scale human brain networks constructed with magnetic resonance imaging. This text is ideally suited to neuroscientists wanting to develop expertise in the rapidly developing field of neural connectomics, and to physical and computational scientists wanting to understand how these quantitative methods can be used to understand brain organization. Extensively illustrated throughout by graphical representations of key mathematical concepts and their practical applications to analyses of nervous systems Comprehensively covers graph theoretical analyses of structural and functional brain networks, from microscopic to macroscopic scales, using examples based on a wide variety of experimental methods in neuroscience Designed to inform and empower scientists at all levels of experience, and from any specialist background, wanting to use modern methods of network science to understand the organization of the brain
Author: Alexander I. Zhmakin Publisher: Springer Science & Business Media ISBN: 3540887857 Category : Science Languages : en Pages : 286
Book Description
This book covering the basics and the state-of-the-art of cryobiology and its applications emphasizes the underlying physical phenomena. It includes a comprehensive glossary and appendices for deeper exploration into special issues.
Author: Wanda M. Haschek Publisher: Academic Press ISBN: 0128098422 Category : Medical Languages : en Pages : 902
Book Description
Fundamentals of Toxicologic Pathology, Third Edition, presents an essential overview of systems toxicologic pathology in a clear-and-concise manner. Toxicologic pathology integrates toxicology and its interdisciplinary components, including biochemistry, pharmacodynamics and risk assessment to pathology and its related disciplines, such as physiology, microbiology, immunology and molecular biology. This wholly revised and updated edition presents the newest information on the topic, and is an essential reference for advanced students, early career researchers, toxicologic pathologists, pharmaceutical scientists, medical pathologists and clinicians, and anyone involved with drug and device development. The book includes a new section describing the application of toxicologic pathology, such as diagnostic and forensic toxicologic pathology, environmental toxicologic pathology, experimental and industrial toxicologic pathology, and pathology issues in the design of toxicology studies. There are also new chapters on special senses (the eye and ear) and the biochemical and molecular basis of toxicity, among others. Presents revised and updated information for each chapter on systems Contains expanded sections on applied toxicologic pathology Includes the essential information necessary to understand toxicologic pathology in an accessible language
Author: Larry E. Davis, M.D. Publisher: Springer ISBN: 1493923595 Category : Medical Languages : en Pages : 294
Book Description
This concise text delivers a basic introduction to neurology and is designed for use by medical students during their rotation in neurology and related disciplines. Updated and expanded, this second edition follows the same order as the first, starting with how to approach a patient with a neurologic problem followed by the latest information on the phenomenology, pathophysiology and symptoms of common adult and pediatric neurologic diseases. Supplementing the learning experience are clinical cases that begin each chapter and videos of examples ranging from how to perform the normal neurologic exam to abnormal exam findings. Easy-to-read and richly illustrated, Fundamentals of Neurologic Disease, 2nd Edition is an invaluable resource for anyone seeking to learn the fundamentals of neurology.
Author: Robert Marcus Publisher: Academic Press ISBN: 012375108X Category : Medical Languages : en Pages : 551
Book Description
Fundamentals of Osteoporosis offers a concise yet comprehensive source of all the latest basic research related to osteoporosis in one reference work. Experts from all areas of osteoporosis research expose readers to genomic and proteomic analysis, and histopathology and imaging, as well cellular and molecular mechanisms relevant to assay development and drug discovery. Presents a concise yet comprehensive source of all the latest basic research related to osteoporosis in one reference work Experts from all areas of osteoporosis research expose readers to genomic and proteomic analysis, histopathology and imaging, as well cellular and molecular mechanisms relevant to assay development and drug discovery Clear, concise presentations by bone biologists of the cellular and molecular mechanisms underlying osteoporosis
Author: Mirza Hasanuzzaman Publisher: Springer Nature ISBN: 9811521727 Category : Science Languages : en Pages : 866
Book Description
This book presents the state-of-the-art in plant ecophysiology. With a particular focus on adaptation to a changing environment, it discusses ecophysiology and adaptive mechanisms of plants under climate change. Over the centuries, the incidence of various abiotic stresses such as salinity, drought, extreme temperatures, atmospheric pollution, metal toxicity due to climate change have regularly affected plants and, and some estimates suggest that environmental stresses may reduce the crop yield by up to 70%. This in turn adversely affects the food security. As sessile organisms, plants are frequently exposed to various environmental adversities. As such, both plant physiology and plant ecophysiology begin with the study of responses to the environment. Provides essential insights, this book can be used for courses such as Plant Physiology, Environmental Science, Crop Production and Agricultural Botany. Volume 2 provides up-to-date information on the impact of climate change on plants, the general consequences and plant responses to various environmental stresses.
Author: Ralph Kirby,T.G. Downing and M.I.El Gohary Publisher: EOLSS Publications ISBN: 1848264089 Category : Languages : en Pages : 346
Book Description
Fundamentals of Biochemistry, Cell Biology and Biophysics is a component of Encyclopedia Of Biological, Physiological And Health Sciences in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. This 3-volume set contains several chapters, each of size 5000-30000 words, with perspectives, issues on. Biological Science Foundations; Organic Chemicals Involved In Life Processes; Carbon Fixation; Anaerobic and Aerobic Respiration; Biochemistry; Inorganic Biochemistry; Soil Biochemistry; Organic Chemistry And Biological Systems -Biochemistry; Eukaryote Cell Biology; Cell Theory, Properties Of Cells And Their Diversity; Cell Morphology And Organization; Cell Nucleus And Chromatin Structure; Organelles And Other Structures In Cell Biology; Mitosis, Cytokines is, Meiosis And Apoptosis; Cell Growth Regulation, Transformation And Metastases; Networks In Cell Biology; Microbiology; Prokaryotic Cell Structure And Function; Prokaryotic Diversity; Prokaryote Genetics; Prokaryotic Growth, Nutrition And Physiology; An Introductory Treatise On Biophysics; Mathematical Models In Biophysics. It is aimed at the following five major target audiences: University and College Students, Educators, Professional Practitioners, Research Personnel and Policy Analysts, Managers, and Decision Makers.
Author: Anthony K. Campbell
Author: Anthony K. Campbell
Author: Claus W. Heizmann
Author: Claus W Heizmann
Author: Alex Fornito
Author: Alexander I. Zhmakin
Author: Wanda M. Haschek
Author: Larry E. Davis, M.D.
Author: Robert Marcus
Author: Mirza Hasanuzzaman
Author: Ralph Kirby,T.G. Downing and M.I.El Gohary