Author: Yong-Kyu Kim Publisher: Springer Science & Business Media ISBN: 0387767274 Category : Medical Languages : en Pages : 557
Book Description
This handbook provides research guidelines to study roles of the genes and other factors involved in a variety of complex behaviors. Utilizing methodologies and theories commonly used in behavior genetics, each chapter features an overview of the selected topic, current issues, as well as current and future research.
Author: Yong-Kyu Kim Publisher: Springer ISBN: 9780387767260 Category : Medical Languages : en Pages : 564
Book Description
This handbook provides research guidelines to study roles of the genes and other factors involved in a variety of complex behaviors. Utilizing methodologies and theories commonly used in behavior genetics, each chapter features an overview of the selected topic, current issues, as well as current and future research.
Author: Kathryn E. Hood Publisher: John Wiley & Sons ISBN: 1444351680 Category : Psychology Languages : en Pages : 772
Book Description
The Handbook of Developmental Science, Behavior, and Genetics brings together the cutting-edge theory, research and methodology that contribute to our current scientific understanding of the role of genetics in the developmental system. • Commemorates the historically important contributions made by Gilbert Gottlieb in comparative psychology and developmental science • Includes an international group of contributors who are among the most respected behavioral and biological scientists working today • Examines the scientific basis for rejecting the reductionism and counterfactual approach to understanding the links between genes, behavior, and development • Documents the current status of comparative psychology and developmental science and provides the foundation for future scientific progress in the field
Author: Wim E. Crusio Publisher: Cambridge University Press ISBN: 1107355575 Category : Science Languages : en Pages :
Book Description
The first volume in the new Cambridge Handbooks in Behavioral Genetics series, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically modified or pharmacologically treated animals and in the interpretation and analyses of the results obtained. The book offers a comprehensive overview of the genetics of naturally occurring variation in mouse behavior, from perception and spontaneous behaviors such as exploration, aggression, social interactions and motor behaviors, to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.
Author: Wim E. Crusio Publisher: Elsevier ISBN: 9780080536866 Category : Psychology Languages : en Pages : 962
Book Description
The book gives a broad overview of recombinant DNA techniques for the behavioral neuroscientist, with illustrative examples of applications. Species covered include rodents (mainly mice), Drosophila melanogaster, Caenorhabditis elegans and Danio rerio. Experimental techniques required to characterize the behavioral phenotypes of mutant animals is provided. Several aspects of novel molecular-genetic techniques are overviewed and possible research strategies are explained. The sections of the book start with general descriptions of techniques followed by illustrative examples. It is divided into six sections. Section 1, bioinformatics and genomics research. Section 2, top-down strategies, where the researcher starts with the phenotype and then analyzes the associated genes; bottom-up strategies, where the physiological chain leading to a phenotype is analyzed starting from the gene product. Section 3, transgenic approaches in rodents including overexpressing foreign genes and gene-targeting; systemic manipulation approaches directly targeting the central nervous system and methods used with invertebrates. Section 4, methods used to evaluate relevant behavioral phenotypes, including learning and aggression. Section 5, examples on molecular brain research in man. Section 6, ethical aspects of research in this field.
Author: Jonathan C. Gewirtz Publisher: Springer ISBN: 1493937774 Category : Medical Languages : en Pages : 389
Book Description
This stimulating analysis reviews the broad potential of animal models to foster a deeper understanding of human pathology, strengthen connections between genetic and behavioral studies, and develop more effective treatments for mental disorders. Widely-studied and lesser-used species are examined in models that capture features along the continuum of normative and pathological behavior. The models highlight genetic causes of core features, or endophenotypes, of developmental, internalizing, and externalizing disorders, as well as dementia. Expert contributors address questions ranging from how suitable species are chosen for study to the costs and benefits of using inbred versus outbred strains, and the effects of housing environment on subject animals. Larger issues addressed include how to evaluate the applicability of animal behavioral models to the human condition and how these models can harness emerging molecular technologies to further our understanding of the genetic basis of mental illness. Included in the coverage: Mating and fighting in Drosophila. Attachment and social bonding. Impulsivity in rodents and humans. Animal models of cognitive decline. Animal models of social cognition. Future directions for animal models in behavioral genetics. A detailed map of where this evolving field is headed, Animal Models of Behavior Genetics shows geneticists, molecular biologists, and cognitive neuroscientists paths beyond established concepts toward a more knowledgeable and collaborative future.
Author: Daniel J. Flannery Publisher: Cambridge University Press ISBN: 1139465678 Category : Psychology Languages : en Pages :
Book Description
From a team of leading experts comes a comprehensive, multidisciplinary examination of the most current research including the complex issue of violence and violent behavior. The handbook examines a range of theoretical, policy, and research issues and provides a comprehensive overview of aggressive and violent behavior. The breadth of coverage is impressive, ranging from research on biological factors related to violence and behavior-genetics to research on terrrorism and the impact of violence in different cultures. The authors examine violence from international cross-cultural perspectives, with chapters that examine both quantitative and qualitative research. They also look at violence at multiple levels: individual, family, neighborhood, cultural, and across multiple perspectives and systems, including treatment, justice, education, and public health.
Author: Philip David Zelazo Publisher: Oxford University Press ISBN: 0199958459 Category : Medical Languages : en Pages : 1049
Book Description
This handbook provides a comprehensive survey of what is now known about psychological development, from birth to biological maturity, and it highlights how cultural, social, cognitive, neural, and molecular processes work together to yield human behavior and changes in human behavior.
Author: Christian P. Muller Publisher: Academic Press ISBN: 0080878172 Category : Science Languages : en Pages : 849
Book Description
Serotonin (5-hydroxytryptamine, often cited as 5-HT) is one of the major excitatory neurotransmitter, and the serotonergic system is one of the best studied and understood transmitter systems. It is crucially involved in the organization of virtually all behaviours and in the regulation of emotion and mood. Alterations in the serotonergic system, induced by e.g. learning or pathological processes, underlie behavioural plasticity and changes in mood, which can finally results in abnormal behaviour and psychiatric conditions. Not surprisingly, the serotonergic system and its functional components appear to be targets for a multitude of pharmacological treatments - examples of very successful drugs targeting the serotoninergic system include Prozac and Zoloft. The last decades of research have not only fundamentally expanded our view on serotonin but also revealed in much more detail an astonishing complexity of this system, which comprises a multitude of receptors and signalling pathways. A detailed view on its role in basal, but also complex, behaviours emerged, and, was presented in a number of single review articles. Although much is known now, the serotonergic system is still a fast growing field of research contributing to our present understanding of the brains function during normal and disturbed behaviour. This handbook aims towards a detailed and comprehensive overview over the many facets of behavioural serotonin research. As such, it will provide the most up to date and thorough reading concerning the serotonergic systems control of behaviour and mood in animals and humans. The goal is to create a systematic overview and first hand reference that can be used by students and scholars alike in the fields of genetics, anatomy, pharmacology, physiology, behavioural neuroscience, pathology, and psychiatry. The chapters in this book will be written by leading scientists in this field. Most of them have already written excellent reviews in their field of expertise. The book is divided in 4 sections. After an historical introduction, illustrating the growth of ideas about serotonin function in behaviour of the last forty years, section A will focus on the functional anatomy of the serotonergic system. Section B provides a review of the neurophysiology of the serotonergic system and its single components. In section C the involvement of serotonin in behavioural organization will be discussed in great detail, while section D deals with the role of serotonin in behavioural pathologies and psychiatric disorders. The first handbook broadly discussing the behavioral neurobiology of the serotonorgic transmitter system Co-edited by one of the pioneers and opinion leaders of the past decades, Barry Jacobs (Princeton), with an international list (10 countries) of highly regarded contributors providing over 50 chapters, and including the leaders in the field in number of articles and citations: K. P. Lesch, T. Sharp, A. Caspi, P. Blier, G.K. Aghajanian, E. C. Azmitia, and others The only integrated and complete resource on the market containing the best information integrating international research, providing a global perspective to an international community Of great value not only for researchers and experts, but also for students and clinicians as a background reference
Author: Yong-Kyu Kim
Author: Yong-Kyu Kim
Author: Kathryn E. Hood
Author: Wim E. Crusio
Author: Wim E. Crusio
Author: Jonathan C. Gewirtz
Author: Josh Dubnau
Author: Daniel J. Flannery
Author: Philip David Zelazo
Author: Christian P. Muller