Author: Richard E. Tucker Publisher: Springer Science & Business Media ISBN: 146133599X Category : Science Languages : en Pages : 793
Book Description
Increasing international concern is being expressed regarding the contamination of the environment with polychlorinated dibenzo-p dioxins (PCDDs) and polychlorinated dibenzofurans because certain of these chemicals have been shown to be highly toxic to animals and are ubiquitous in the environment. They are known to be distributed as contaminants of commercial products and as by-products from com bustion processes. A considerable volume of information has accumulated on these chemicals in the past two decades, particularly for the most toxic of them, 2,3,7,8-tetrach1orodibenzo-p-dioxin (2,3,7,8-TCDD). However, this body of knowledge has not succeeded in resolving genuine judgmental differences among experts in the field as to the degree of hazard to human health and the environment. In light of the widespread public concern, it is clearly imperative to come to grips with the continuing scientific controversy, to review the data, assess the issues, to see where areas of agreement exist, and where further research is needed to resolve remaining areas of disagree ment. This volume represents an effort to contribute to these goals.
Author: O. Hutzinger Publisher: Elsevier ISBN: 1483285871 Category : Science Languages : en Pages : 670
Book Description
The complex multidisciplinary problem posed by PCDD can best be understood by the interaction of scientists from different disciplines. This workshop was organised to allow scientific exchange by such experts. The most recent advances in analytical methodology, environmental fate and levels, incineration toxicology (metabolism), animal toxicology and observations in man are covered
Author: National Research Council Publisher: National Academies Press ISBN: 0309133882 Category : Science Languages : en Pages : 269
Book Description
Although the U.S. Environmental Protection Agency presented a comprehensive review of the scientific literature in its 2003 draft reassessment of the risks of dioxin, the agency did not sufficiently quantify the uncertainties and variabilities associated with the risks, nor did it adequately justify the assumptions used to estimate them, according to this new report from the National Academies' National Research Council. The committee that wrote the report recommended that EPA re-estimate the risks using several different assumptions and better communicate the uncertainties in those estimates. The agency also should explain more clearly how it selects both the data upon which the reassessment is based and the methods used to analyze them.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309051401 Category : Medical Languages : en Pages : 988
Book Description
People are increasingly concerned about potential environmental health hazards and often ask their physicians questions such as: "Is the tap water safe to drink?" "Is it safe to live near power lines?" Unfortunately, physicians often lack the information and training related to environmental health risks needed to answer such questions. This book discusses six competency based learning objectives for all medical school students, discusses the relevance of environmental health to specific courses and clerkships, and demonstrates how to integrate environmental health into the curriculum through published case studies, some of which are included in one of the book's three appendices. Also included is a guide on where to obtain additional information for treatment, referral, and follow-up for diseases with possible environmental and/or occupational origins.
Author: Mehran Alaee Publisher: Springer ISBN: 3319238892 Category : Science Languages : en Pages : 462
Book Description
This volume is a tribute to Professor Otto Hutzinger, the founding editor of The Handbook of Environmental Chemistry, in recognition of his pioneering work and contribution to our understanding of the sources, fate, exposure and effects of persistent organic pollutants. It consists of fourteen chapters written by individuals who have been inspired by his work and have followed in his footsteps by refining our knowledge of this field and opening new research directions. In Professor Hutzinger’s tradition of passing on valuable information to others, the authors present recent advances in areas such as inventories, remediation, and analytical determinations. Levels and trends in abiotic environments, biota, and human exposure via food, as well as the risks to the environment and humans from polychlorinated dibenzo dioxins, furans, and PCBs are also discussed. Other chapters deal with the relevant topics of DDT and its metabolites along with halogenated and phosphorus flame retardants.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309089611 Category : Science Languages : en Pages : 341
Book Description
Dioxin and dioxin-like compounds, or DLCs, are found throughout the environment, in soil, water, and air. People are exposed to these unintentional environmental contaminants primarily through the food supply, although at low levels, particularly by eating animal fat in meat, dairy products, and fish. While the amount of DLCs in the environment has declined since the late 1970s, the public continues to be concerned about the safety of the food supply and the potential adverse health effects of DLC exposure, especially in groups such as developing fetuses and infants, who are more sensitive to the toxic effects of these compounds. Dioxins and Dioxin-like Compounds in the Food Supply: Strategies to Decrease Exposure, recommends policy options to reduce exposure to these contaminants while considering how implementing these options could both reduce health risks and affect nutrition, particularly in sensitive and highly exposed groups, if dietary changes are suggested.
Author: A. Schecter Publisher: Springer Science & Business Media ISBN: 1489914625 Category : Science Languages : en Pages : 718
Book Description
This book originated in a series of cross-disciplinary conversations in the years 1984-1990 between the editor, who is a physician-researcher involved in clinical and laboratory research, and a dioxin toxicologist. During the years in which the conversations took place, an extraordinary amount of new scientific literature was published related to dioxins, defined for purposes of this text as the chlorinated dibenzo-p-dioxins, dibenzofurans, polychlorinated biphe nyls (PCB's) and other compounds that are structurally and toxicologically similar to 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7 ,8-TCDD), the most extensively studied and most toxic of this group of chemicals. Dioxins also began to interest not only chemists and toxicologists, but also specialists from diverse disciplines such as wildlife and environmental science, immunology, neuroscience,public health, epidemiology, med icine, government, law, sociology, and journalism. Specialists from such varied disciplines, while familiar with their own literature, frequently did not have time to follow the dioxin literature outside their specialty area. In addition, each specialty had unique knowledge, methods, and perspectives. Cross disciplinary conversation was necessary, but all too frequently, specialists from the various disciplines did not speak the same language, resulting in misunderstanding.
Author: Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides Publisher: National Academies Press ISBN: 9780309075299 Category : Medical Languages : en Pages : 791
Book Description
Have U.S. military personnel experienced health problems from being exposed to Agent Orange, its dioxin contaminants, and other herbicides used in Vietnam? This definitive volume summarizes the strength of the evidence associating exposure during Vietnam service with cancer and other health effects and presents conclusions from an expert panel. Veterans and Agent Orange provides a historical review of the issue, examines studies of populations, in addition to Vietnam veterans, environmentally and occupationally exposed to herbicides and dioxin, and discusses problems in study methodology. The core of the book presents What is known about the toxicology of the herbicides used in greatest quantities in Vietnam. What is known about assessing exposure to herbicides and dioxin. What can be determined from the wide range of epidemiological studies conducted by different authorities. What is known about the relationship between exposure to herbicides and dioxin, and cancer, reproductive effects, neurobehavioral disorders, and other health effects. The book describes research areas of continuing concern and offers recommendations for further research on the health effects of Agent Orange exposure among Vietnam veterans. This volume will be critically important to both policymakers and physicians in the federal government, Vietnam veterans and their families, veterans organizations, researchers, and health professionals.
Author: Erich W. Bretthauer Publisher: Springer Science & Business Media ISBN: 1461533082 Category : Medical Languages : en Pages : 785
Book Description
Erich W. Bretthauer, Chairman of the Exposure and Hazard Assessment Working Group U. s. Environmental Protection Agency Washington, D. C. The efforts of the Exposure and Hazard Assessment Working Group were focused on the exchange of information on a variety of topics including research projects, regulations/statutes, analytical laboratories, and methods of exposure/risk assessment involving CDDs and CDFs. It was evident to the leaders of the Working Group that several of the knowledge voids had to be addressed on a fundamental level before expanded efforts could be made. Several questions needed to be answered: • Who has done research on this topic, and what do the data indicate? • Who is performing research now, and what are their capabilities? • How are other nations addressing this problem, and do they have legislative mandates in place? • Is there a general consensus on the topic? The members of the Working Group believed that these questions could be answered by surveying the major participants in the field of interest. Three principal survey efforts were performed by the Working Group, which collected information on research, regulations/statutes, and analytical laboratories from each of the participating nations. In addition to answering these fundamental questions, these efforts also fulfilled the major objectives of the entire Pilot Study. The collection, analysis, and distribution of information on research projects, regulations/statutes, and analytical laboratories were very useful efforts in helping to fill some of the basic knowledge voids.
Author: Richard E. Tucker
Author: O. Hutzinger
Author: National Research Council
Author: Great Britain. Central Directorate of Environmental Protection
Author: Institute of Medicine
Author: Mehran Alaee
Author: Institute of Medicine
Author: A. Schecter
Author: Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides
Author: Erich W. Bretthauer