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Author: Elizabeth Fiona McInnes Publisher: Elsevier Health Sciences ISBN: 0702049247 Category : Medical Languages : en Pages : 256
Book Description
Background Lesions in Laboratory Animals will be an invaluable aid to pathologists needing to recognize background and incidental lesions while examining slides taken from laboratory animals in acute and chronic toxicity studies, or while examining exotic species in a diagnostic laboratory. It gives clear descriptions and illustrations of the majority of background lesions likely to be encountered. Many of the lesions covered are unusual and can be mistaken for treatment-related findings in preclinical toxicity studies. The Atlas has been prepared with contributions from experienced toxicological pathologists who are specialists in each of the laboratory animal species covered and who have published extensively in these areas. over 600 high-definition, top-quality color photographs of background lesions found in rats, mice, dogs, minipigs, non-human primates, hamsters, guinea pigs and rabbits a separate chapter on lesions in the reproductive systems of all laboratory animals written by Dr Dianne Creasy, a world expert on testicular lesions in laboratory animals a chapter on common artifacts that may be observed in histological glass slides extensive references to each lesion described aging lesions encountered in all laboratory animal species, particularly in rats in mice which are used for carcinogenicity studies
Author: Elizabeth Fiona McInnes Publisher: Elsevier Health Sciences ISBN: 0702049247 Category : Medical Languages : en Pages : 256
Book Description
Background Lesions in Laboratory Animals will be an invaluable aid to pathologists needing to recognize background and incidental lesions while examining slides taken from laboratory animals in acute and chronic toxicity studies, or while examining exotic species in a diagnostic laboratory. It gives clear descriptions and illustrations of the majority of background lesions likely to be encountered. Many of the lesions covered are unusual and can be mistaken for treatment-related findings in preclinical toxicity studies. The Atlas has been prepared with contributions from experienced toxicological pathologists who are specialists in each of the laboratory animal species covered and who have published extensively in these areas. over 600 high-definition, top-quality color photographs of background lesions found in rats, mice, dogs, minipigs, non-human primates, hamsters, guinea pigs and rabbits a separate chapter on lesions in the reproductive systems of all laboratory animals written by Dr Dianne Creasy, a world expert on testicular lesions in laboratory animals a chapter on common artifacts that may be observed in histological glass slides extensive references to each lesion described aging lesions encountered in all laboratory animal species, particularly in rats in mice which are used for carcinogenicity studies
Author: National Research Council Publisher: National Academies Press ISBN: 0309038391 Category : Science Languages : en Pages : 113
Book Description
Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.
Author: Kristine Coleman Publisher: CRC Press ISBN: 0429671296 Category : Medical Languages : en Pages : 1088
Book Description
CHOICE Highly Recommended title, 2022! This 30-chapter volume informs students and professionals about the behavioral biology of animals commonly housed in laboratory and other captive settings. Each species evolved under specific environmental conditions, resulting in unique behavioral patterns, many of which are maintained in captivity even after generations of breeding. Understanding natural behavior is therefore a critical part of modern animal care practices. The descriptions, data, guidance, resources, and recommendations in this book will help the reader understand their animals better, refine the care and treatment that they receive, and improve the well-being, welfare, and wellness of their animals. The book is divided into three sections, all focusing on aspects of the behavioral biology of animals found in laboratories and related research settings. After five introductory chapters, 25 chapters are dedicated to specific taxonomic groups (including mice, zebrafish, zebra finches, reptiles, macaques) while a concluding section of ethograms provides a centralized resource for those interested in understanding, and potentially quantifying, animal behavior. The Behavioral Biology of Laboratory Animals will provide anyone working in maintenance, care, and/or research programs that involve laboratory animals with information about the way the animals live in the wild, and the way that they should live in captive research settings. Many of the guidelines and recommendations will also be valuable to those managing and working with animals in other environments, including zoological parks, aquaria, and sanctuaries.
Author: National Research Council Publisher: National Academies Press ISBN: 0309051266 Category : Science Languages : en Pages : 188
Book Description
In the years since the third edition of this indispensable reference was published, a great deal has been learned about the nutritional requirements of common laboratory species: rat, mouse, guinea pig, hamster, gerbil, and vole. The Fourth Revised Edition presents the current expert understanding of the lipid, carbohydrate, protein, mineral, vitamin, and other nutritional needs of these animals. The extensive use of tables provides easy access to a wealth of comprehensive data and resource information. The volume also provides an expanded background discussion of general dietary considerations. In addition to a more user-friendly organization, new features in this edition include: A significantly expanded section on dietary requirements for rats, reporting substantial new findings. A new section on nutrients that are not required but that may produce beneficial results. New information on growth and reproductive performance among the most commonly used strains of rats and mice and on several hamster species. An expanded discussion of diet formulation and preparationâ€"including sample diets of both purified and natural ingredients. New information on mineral deficiency and toxicity, including warning signs. This authoritative resource will be important to researchers, laboratory technicians, and manufacturers of laboratory animal feed.
Author: Trenton R Schoeb Publisher: Academic Press ISBN: 0128045833 Category : Medical Languages : en Pages : 428
Book Description
Gnotobiotics summarizes and analyzes the research conducted on the use of gnotobiotes, providing detailed information regarding actual facility operation and derivation of gnotobiotic animals. In response to the development of new tools for microbiota and microbiome analysis, the increasing recognition of the various roles of microbiota in health and disease, and the consequent expanding demand for gnotobiotic animals for microbiota/microbiome related research, this volume collates the research of this expanding field into one definitive resource. Reviews and defines gnotobiotic animal species Analyzes microbiota in numerous contexts Presents detailed coverage of the protocols and operation of a gnotobiotic facility
Author: Institute of Laboratory Animal Resources (U.S.). Committee on Care and Use of Laboratory Animals Publisher: ISBN: Category : Laboratory animals Languages : en Pages : 84
Author: Paul Flecknell Publisher: Academic Press ISBN: 9780080918990 Category : Medical Languages : en Pages : 304
Book Description
Laboratory Animal Anesthesia looks at recent significant developments in anesthetic practices in laboratory experiments involving animals. It also provides information about basic standards for proper use of anesthesia. In addition, it examines the equipment and different anesthetic agents that are used in performing an experiment on animals. The book also discusses the profound effects of anesthesia on the physiological aspect of the animals’ body systems, such as hypothermia and respiratory depression. The book addresses the proper management and care that should be provided for the animals that undergo anesthesia. Furthermore, it covers different anesthetic procedures that should be used on various kinds of small animals intended for laboratory experiments. The main goal of this book is to provide information about the different anesthetic agents used in experiments, and the proper standards to follow when using anesthetics on lab animals. • New edition provides new information on anesthesia and analgesia, and has an extensively revised and updated bibliography • Provides a balanced consideration of the needs of scientific research and the welfare of laboratory animals • Written by a veterinary anesthetist and scientist with over 30 years' experience in the field, and who is actively engaged in research in this area • Provides rapid, easily accessed information using tabulated summaries • Provides those with limited experience of anesthesia with the information they need to carry our procedures effectively, safely, and humanely • Provides sufficient depth for the more experienced anesthetist moving to this field
Author: Jeffrey W. Richig Publisher: Academic Press ISBN: 0124159990 Category : Science Languages : en Pages : 144
Book Description
Electrocardiography of Laboratory Animals is the only book covering electrocardiography of laboratory animals, including dogs, mini-pigs, and cynomologus monkeys. As more countries institute requirements for the care of laboratory animals in research, this publication offers an effective standard on performing and analyzing ECGs. Topics covered include safety electrocardiography, toxicology, safety pharmacology, and telemetry. Electrocardiography of Laboratory Animals will assist biological and medical researchers, veterinarians, zoologists, and students in understanding electrocardiography of various species of animals used in research. Covers safety electrocardiography of large laboratory animals Offers comprehensive analysis of ECGs for practical laboratory use Includes a self-evaluation section for testing of ECG reading and analysis
Author: National Research Council Publisher: National Academies Press ISBN: 0309101107 Category : Science Languages : en Pages : 165
Book Description
Arranging the transportation of animals at research facilities is often an ordeal. There is a confusing patchwork of local, national, and international regulations; a perceived lack of high-quality shipping services; a dearth of science-based good practices; and a lack of biosafety standards. It's a challenge â€"and an impediment to biomedical research. Guidelines for the Humane Transportation of Research Animals identifies the current problems encountered in the transportation of research animals and offers recommendations aimed at local and federal officials to rectify these problems. This book also includes a set of good practices based on the extensive body of literature on transportation of agricultural animals, universal concepts of physiology, and a scientific understanding of species-specific needs and differences. Good practices were developed by the committee to address thermal environment, space requirements, food and water requirements, social interaction, monitoring of transportation, emergency procedures, personnel training, and biosecurity. Guidelines for the Humane Transportation of Research Animals is an essential guide for all researchers, animal care technicians, facilities managers, administrators, and animal care and use committees at research institutions.
Author: Kurt Leroy Hoffman Publisher: Woodhead Publishing ISBN: 0081001061 Category : Medical Languages : en Pages : 324
Book Description
Modeling Neuropsychiatric Disorders in Laboratory Animals serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals interested in the use of animal models in preclinical research related to human neuropsychiatric disorders. The text focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders. Chapters contain discussions on both classical and modern views on the validation of animal models for neuropsychiatric disorders, also discussing the utility of endophenotypes in modeling neuropsychiatric disease. Subsequent chapters deal with four specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders. Final sections discuss the future for the development, validation, and use of animal models in basic and preclinical research. Focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders Serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals Discusses specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders
Author: Elizabeth Fiona McInnes
Author: Elizabeth Fiona McInnes
Author: National Research Council
Author: Kristine Coleman
Author: National Research Council
Author: Trenton R Schoeb
Author: Institute of Laboratory Animal Resources (U.S.). Committee on Care and Use of Laboratory Animals
Author: Paul Flecknell
Author: Jeffrey W. Richig
Author: National Research Council
Author: Kurt Leroy Hoffman