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Author: Vincent Henrich Publisher: Academic Press ISBN: 0128160160 Category : Science Languages : en Pages : 240
Book Description
In Managing Health in the Genomic Era: A Guide to Family Health History and Disease Risk, Drs. Vincent C. Henrich, Lori A. Orlando, and Brian H. Shirts discuss the practical considerations surrounding the use of genomic and genetic tests to manage patient health, to provide adult disease risk assessment, to improve diagnosis, and to support effective interventions and treatment. In 10 chapters, evidence-based information and case studies are described and examine the central place of family health history (FHH) in genomic medicine, tools and strategies for compiling and analyzing family health history, how to identify existing and novel genetic markers, how to identify lineage specific (or rare) variants within families, and how to find effective interventions based on genetic testing results and FHH. Factors that influence clinical practice, including gene-environment interactions, FHH social networking, direct to consumer (DTC) genetic testing and data sharing, algorithms for analyzing genetic data, and patient counseling are discussed from the standpoint of clinical practice. Here, frontline healthcare providers will discover succinct commentary and key examples to assist with their local needs. Relevant principles of genetic biology and inheritance are explored and guidance on available support networks and online resources is also provided. 2021 PROSE Awards - Winner: Category: Clinical Medicine: Association of American Publishers Presents a practical, accessible resource for primary care providers, allied health professionals, pharmacologists, public health professionals, students and clinical researchers Addresses genetic and genomic approaches in managing patient health, conducting and analyzing family health histories, and assessing adult disease risk Features an expert author team with direct experience integrating genetics and genomics in primary care and family medicine settings Examines the attributes and limitations of family health history, genetic testing, and genomic testing in clinical practice Includes detailed explanations following practice-based examples
Author: Vincent Henrich Publisher: Academic Press ISBN: 0128160160 Category : Science Languages : en Pages : 240
Book Description
In Managing Health in the Genomic Era: A Guide to Family Health History and Disease Risk, Drs. Vincent C. Henrich, Lori A. Orlando, and Brian H. Shirts discuss the practical considerations surrounding the use of genomic and genetic tests to manage patient health, to provide adult disease risk assessment, to improve diagnosis, and to support effective interventions and treatment. In 10 chapters, evidence-based information and case studies are described and examine the central place of family health history (FHH) in genomic medicine, tools and strategies for compiling and analyzing family health history, how to identify existing and novel genetic markers, how to identify lineage specific (or rare) variants within families, and how to find effective interventions based on genetic testing results and FHH. Factors that influence clinical practice, including gene-environment interactions, FHH social networking, direct to consumer (DTC) genetic testing and data sharing, algorithms for analyzing genetic data, and patient counseling are discussed from the standpoint of clinical practice. Here, frontline healthcare providers will discover succinct commentary and key examples to assist with their local needs. Relevant principles of genetic biology and inheritance are explored and guidance on available support networks and online resources is also provided. 2021 PROSE Awards - Winner: Category: Clinical Medicine: Association of American Publishers Presents a practical, accessible resource for primary care providers, allied health professionals, pharmacologists, public health professionals, students and clinical researchers Addresses genetic and genomic approaches in managing patient health, conducting and analyzing family health histories, and assessing adult disease risk Features an expert author team with direct experience integrating genetics and genomics in primary care and family medicine settings Examines the attributes and limitations of family health history, genetic testing, and genomic testing in clinical practice Includes detailed explanations following practice-based examples
Author: Dhavendra Kumar Publisher: Academic Press ISBN: 0127999221 Category : Science Languages : en Pages : 358
Book Description
Medical and Health Genomics provides concise and evidence-based technical and practical information on the applied and translational aspects of genome sciences and the technologies related to non-clinical medicine and public health. Coverage is based on evolving paradigms of genomic medicine—in particular, the relation to public and population health genomics now being rapidly incorporated in health management and administration, with further implications for clinical population and disease management. Provides extensive coverage of the emergent field of health genomics and its huge relevance to healthcare management Presents user-friendly language accompanied by explanatory diagrams, figures, and many references for further study Covers the applied, but non-clinical, sciences across disease discovery, genetic analysis, genetic screening, and prevention and management Details the impact of clinical genomics across a diverse array of public and community health issues, and within a variety of global healthcare systems
Author: Jean F. Jenkins Publisher: Jones & Bartlett Learning ISBN: 9780763733254 Category : Genetic counseling Languages : en Pages : 432
Book Description
Increasingly, genomic-based approaches and resources are redefining our categorization of disease, leading to new approaches to prevention and therapy. As nurses traditionally practice patient-oriented care, they will undoubtedly play a key role in both developing and applying the aspects of genomic health care. Nursing Care in the Genomic Era: A Case Based Approach is designed to provide nurses with up-to-date and accessible information on this powerful new approach to understanding, preventing, and treating disease.
Author: Betty S Pace Publisher: World Scientific ISBN: 1908979917 Category : Medical Languages : en Pages : 396
Book Description
The Human Genome Project has spawned a Renaissance of research faced with the daunting expectation of personalized medicine for individuals with sickle cell disease in the Genome Era. This book offers a comprehensive and timeless account of emerging concepts in clinical and basic science research, and community concerns of health disparity to educate professionals, students and the general public about meeting this challenging expectation. Contributions from physicians, research scientists, scientific administrators and community workers make Renaissance of Sickle Cell Disease Research in the Genome Era unique among the catalogue of books on this genetic disorder. Part 1 offers detailed review of the National Heart Lung and Blood Institute's leadership role in funding sickle cell research, as well as developing progressive research initiatives and the predicted impact of the Human Genome Project. Part 2 gives an account of several clinical research perspectives based on the Cooperative Study of Sickle Cell Disease. These include recommendations for newborn screening, pain management, stroke, transfusion therapy and pediatric and adult healthcare. Part 3 offers novel insights into basic science research progress and the impact of the Human Genome Project on the direction of hemoglobinopathy research, including hemoglobin switching, bone marrow transplantation and gene therapy. Part 4 engages the reader in a culture-based discussion of the stigma attached to sickle cell disease in the African American community and the apprehensions about genetic research in this community. It concludes with a global perspective on sickle cell disease from African, European and American experiences. For readers seeking a definitive account of sickle cell disease appropriate for students, researchers and community workers, this collaborative effort is an ideal textbook. Contents:Sickle Cell Disease: Demystifying the Beginnings (C Reid & G Rodgers)Sponsorship of Sickle Cell Disease Research by the National Institutes of Health: A Brief History and Projections for the Future (G L Evans & D G Badman)The Human Genome Project (B S Pace)Sickle Cell Disease: A Phenotypic Patchwork (K Smith-Whitley & B S Pace)Preventive Care and Advances in the Treatment of Sickle Cell Disease (C T Quinn & G R Buchanan)Sickle Cell Disease in Adults (J Haynes, Jr. & A Pack-Mabien)Pain in Sickle Cell Disease: A Multidimensional Construct (L J Benjamin & R Payne)Transfusion Therapy in Sickle Cell Disease (C Hoppe et al.)Hemoglobin S Polymerization, Just the Beginning (F A Ferrone)Damage to the Red Blood Cell Membrane in Sickle Cell Disease (S R Goodman & C Joiner)Fetal Hemoglobin for What Ails Sickle Hemoglobin (S F Ofori-Acquah & B S Pace)Genetic Modulation of Sickle Cell Disease (M H Steinberg & L T Swee)Molecular Framework of Hemoglobin Switching (S Fiering)Dynamic Nucleoprotein Structure of the ß-Globin Locus: Establishing a Rational Molecular Basis for the Therapeutic Modulation of Hemoglobin Switching (E Bresnick et al.)Vertebrate Models for Sickle Cell Disease Research (B H Paw et al.)Stem Cell Biology (W Li & A W Flake)Bone Marrow Transplantation (R I Raphael & M C Walters)Genetically Engineered Cures: Gene Therapy for Sickle Cell Disease (P Malik & P Leboulch)Sickle Cell Disease: The Past, Present and Future Social and Ethical Dilemmas (V L Bonham, Jr. et al.)It Takes a Village to Cure Sickle Cell Disease (R Peterson & D Davis-Maye)Beyond National Borders: A Global Perspective on Advances in Sickle Cell Disease Research and Management, and New Challenges in the Genome Era (S F Ofori-Acquah & K Ohene-Frempong) Readership: Primary market: Clinical and basic researchers in haematology and genetics, graduate students and postdoctoral fellows; Secondary market: Nursing students, community sickle cell programs, medical school libraries, public library; Tertiary market: Suitable for a graduate course in genetics, genomics as a supplemental text, probably not a primary text. Keywords:Sickle Cell Anemia/Disease;Genomic Era;National Heart Lung and Blood Institute;National Institute of Diabetes and Digestive and Kidney Diseases;Stroke;Pain Management;Fetal Hemoglobin;Hemoglobin Switching;Transgenic Mouse Model;Locus Control Region;African-American Community;Sickle Cell Africa;World Health OrganizationKey Features:Covers the latest progress made in clinical, basic and social research of SCDCaptures the momentum of research efforts related to SCD; this is very timely in light of the plan to perform the first gene therapy treatment in 2006Five out of ten of the current Directors of the National Heart, Lung, and Blood Institute (NHLBI)-funded Comprehensive Sickle Cell Centers are amongst the prominent contributors to the book. These clinical and basic researchers have a major influence in shaping the future focus of programs for sickle cell disease in the United States
Author: Dorothy Nelkin Publisher: University of Michigan Press ISBN: 0472025074 Category : Medical Languages : en Pages : 312
Book Description
"The DNA Mystique is a wake-up call to all who would dismiss America's love affair with 'the gene' as a merely eccentric obsession." --In These Times "Nelkin and Lindee are to be warmly congratulated for opening up this intriguing field [of genetics in popular culture] to further study." --Nature The DNA Mystique suggests that the gene in popular culture draws on scientific ideas but is not constrained by the technical definition of the gene as a section of DNA that codes for a protein. In highlighting DNA as it appears in soap operas, comic books, advertising, and other expressions of mass culture, the authors propose that these domains provide critical insights into science itself. With a new introduction and conclusion, this edition will continue to be an engaging, accessible, and provocative text for the sociology, anthropology, and bioethics classroom, as well as stimulating reading for those generally interested in science and culture.
Author: S. M. Paul Khurana Publisher: Springer Nature ISBN: 9811384991 Category : Science Languages : en Pages : 670
Book Description
Refinement in sequencing technologies and potential of genomic research resulted in meteoric growth of biological information such as sequences of DNA, RNA and protein requiring databases for efficient storage, management and retrieval of the biological information. Also, computational algorithms for analysis of these colossal data became a vital aspect of biological sciences. The work aims to show the process of turning bioscience innovation into companies and products, covering the basic science, the translation of science into technology. Due to rapid developments, there seems to be no basic difference between the pharmaceutical industry and the biotechnological industry. However, approved products in the pipeline and renewed public confidence make it one of the most promising areas of economic growth in the near future. India offers a huge market for the products as well as cheap manufacturing base for export. The book is a sincere work of compilation of new and recent advances in the topic of concern through various innovative researches and scientific opinion therefrom. The book is dedicated to the readers who will definitely find it interesting and knowledgeable in carrying out their respective researches in different aspects of applied microbiology and biotechnology.
Author: Surajit Das Publisher: Elsevier ISBN: 0443133212 Category : Science Languages : en Pages : 840
Book Description
Microbial Diversity in the Genomic Era, Second Edition presents techniques used for microbial taxonomy and phylogeny, along with their applications and respective strengths and challenges. Though many advanced techniques for the identification of unknown bacterium are available in the genomic era, a far fewer number of the total microbial species have been discovered and identified to date. With that in mind, this book incorporates recently developed biosystematics methods and approaches to assess microbial taxonomy, with suitable recommendations for where to apply them across the range of bacterial identification and infectious disease research. Here, international researchers in the field first provide a broad overview of microbial genomics research and microbiome directed medicine, followed by sections on molecular tools for microbial diversity research, extremophilic microbial diversity, functional microbial diversity across application areas, microbial diversity and infectious disease research, and future directions for research. Step-by-step methodologies are provided for key techniques, along with applied case studies breaking down recent research studies into the practical components, illuminating pathways for new studies across the field. This new edition has been fully updated to address advances in the field of microbiome directed medicine, and whole genome sequencing for studying microbial diversity, considering both recent technological advances and new applications areas, from extremophile studies to the latest approaches in human microbiome analysis. Instructs in techniques used for microbial taxonomy and phylogeny, with discussions of their applications and respective pros and cons Reviews the evolving field of microbial typing and the genomic technologies that enable comparative metagenomic analysis of complex microbial environments Covers microbiome directed translational research, as well as whole genome sequencing for studying microbial diversity, with newly added research protocols and case studies Reviews future applications in the field of microbiome directed medicine Features chapter contributions from global experts in the field
Author: Igor Jurisica Publisher: Springer Science & Business Media ISBN: 0387693211 Category : Medical Languages : en Pages : 180
Book Description
Cancer Informatics in Post-Genomic Era provides both the necessary methodology and practical information tools for analyzing data in the field of medical information science. This, of course, requires analytic tools. Those tools are garnered by developing and assessing methods and systems for the acquisition, processing, and interpretation of patient data, aided by scientific discovery. Key challenges in this field include integrating research and clinical care, sharing data, and establishing partnerships within and across sectors of patient diagnosis and treatment.
Author: Shayne Cox Gad Publisher: John Wiley & Sons ISBN: 0470117109 Category : Medical Languages : en Pages : 1681
Book Description
A practical overview of a full rangeof approaches to discovering, selecting, and producing biotechnology-derived drugs The Handbook of Pharmaceutical Biotechnology helps pharmaceutical scientists develop biotech drugs through a comprehensive framework that spans the process from discovery, development, and manufacturing through validation and registration. With chapters written by leading practitioners in their specialty areas, this reference: Provides an overview of biotechnology used in the drug development process Covers extensive applications, plus regulations and validation methods Features fifty chapters covering all the major approaches to the challenge of identifying, producing, and formulating new biologically derived therapeutics With its unparalleled breadth of topics and approaches, this handbook is a core reference for pharmaceutical scientists, including development researchers, toxicologists, biochemists, molecular biologists, cell biologists, immunologists, and formulation chemists. It is also a great resource for quality assurance/assessment/control managers, biotechnology technicians, and others in the biotech industry.
Author: Vincent Henrich
Author: Vincent Henrich
Author: Dhavendra Kumar
Author: Jean F. Jenkins
Author: Betty S Pace
Author: Dorothy Nelkin
Author: S. M. Paul Khurana
Author: Sabrina Sarrocco
Author: Surajit Das
Author: Igor Jurisica
Author: Shayne Cox Gad