OECD Series on Testing and Assessment Guidance Document on the Validation of (Quantitative) Structure-Activity Relationship [(Q)SAR] Models PDF Download

Author: OECD
Publisher: OECD Publishing
ISBN: 9264085440
Category :
Languages : en
Pages : 154

View

Book Description
This document presents principles and helpful guides for validating (Q)SAR technology for a variety of applications.

Author: OECD
Publisher: OECD Publishing
ISBN: 9264274790
Category :
Languages : en
Pages : 85

View

Book Description
In this document the importance of mechanistic consideration in quantitative structure-activity relationship ((Q)SAR) analysis, the critical role of mechanistic consideration in improving various (Q)SAR approaches and possible integrative approaches of combining chemoinformatics and ...

Author: Kunal Roy
Publisher: Springer
ISBN: 3319568507
Category : Science
Languages : en
Pages : 555

View

Book Description
The book covers theoretical background and methodology as well as all current applications of Quantitative Structure-Activity Relationships (QSAR). Written by an international group of recognized researchers, this edited volume discusses applications of QSAR in multiple disciplines such as chemistry, pharmacy, environmental and agricultural sciences addressing data gaps and modern regulatory requirements. Additionally, the applications of QSAR in food science and nanoscience have been included – two areas which have only recently been able to exploit this versatile tool. This timely addition to the series is aimed at graduate students, academics and industrial scientists interested in the latest advances and applications of QSAR.

Author: OECD
Publisher: OECD Publishing
ISBN: 9264221476
Category :
Languages : en
Pages : 156

View

Book Description
This guidance provides additional information on the conduct of studies performed using Test Guidelines 451, 452 and Test Guideline 453.

Author: OECD
Publisher: OECD Publishing
ISBN: 9264085831
Category :
Languages : en
Pages : 99

View

Book Description
This guidance document provides guidance for assessing the hazards of chemical substances while gaining efficiencies and improving animal welfare. The approach described in this guidance document is to consider closely related chemicals as a group, or category, rather than as individual chemicals.

Author: OECD
Publisher: OECD Publishing
ISBN: 9264274820
Category :
Languages : en
Pages : 23

View

Book Description
With a view to assisting the evaluation of integrated approaches to testing and assessment (IATA) in regulatory decision-making within OECD Member Countries, this guidance document provides a set of principles for reporting defined approaches to testing and assessment that can be used as one of ...

Author: OECD
Publisher: OECD Publishing
ISBN: 9264274677
Category :
Languages : en
Pages : 141

View

Book Description
This guidance document is part of the OECD effort to provide guidance for assessing the hazards of chemical substances while gaining efficiencies and improving animal welfare. The approach described in this guidance document is to consider closely related chemicals as a group, or category ...

Author: Huixiao Hong
Publisher: Elsevier
ISBN: 044315340X
Category : Science
Languages : en
Pages : 566

View

Book Description
QSAR in Safety Evaluation and Risk Assessment provides comprehensive coverage on QSAR methods, tools, data sources, and models focusing on applications in products safety evaluation and chemicals risk assessment. Organized into five parts, the book covers almost all aspects of QSAR modeling and application. Topics in the book include methods of QSAR, from both scientific and regulatory viewpoints; data sources available for facilitating QSAR models development; software tools for QSAR development; and QSAR models developed for assisting safety evaluation and risk assessment. Chapter contributors are authored by a lineup of active scientists in this field. The chapters not only provide professional level technical summarizations but also cover introductory descriptions for all aspects of QSAR for safety evaluation and risk assessment. Provides comprehensive content about the QSAR techniques and models in facilitating the safety evaluation of drugs and consumer products and risk assesment of environmental chemicals Includes some of the most cutting-edge methodologies such as deep learning and machine learning for QSAR Offers detailed procedures of modeling and provides examples of each model's application in real practice

Author: Tomasz Puzyn
Publisher: Springer Science & Business Media
ISBN: 1402097832
Category : Science
Languages : en
Pages : 428

View

Book Description
This book presents an interdisciplinary overview on the most recent advances in QSAR studies. The first part consists of a comprehensive review of QSAR methodology. The second part highlights the interdisciplinary aspects and new areas of QSAR modelling.

Author: Mihai V. Putz
Publisher: Springer
ISBN: 9401795673
Category : Science
Languages : en
Pages : 394

View

Book Description
This title reports the state-of-the-art advancements in modeling and characterization of fundamental and the recently designed carbon based nanocomposites (graphenes, fullerenes, polymers, crystals and allotropic forms). Written by leading experts in the field, the book explores the quantification, indexing, and interpretation of physical and chemical exotic properties related with space-time structure-evolution, phase transitions, chemical reactivity, and topology. Exotic Properties of Carbon Nanomatter is aimed at researchers in academia and industry.