pH of the Skin: Issues and Challenges

pH of the Skin: Issues and Challenges PDF Author: C. Surber
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318063851
Category : Medical
Languages : en
Pages : 214

Book Description
The concept of expressing acidity as the negative logarithm of the hydrogen ion concentration was defined and termed pH in the beginning of the 20th century. The general usefulness of the pH concept for life science was recognized and later gained importance to analytical research. Reports on results of pH measurements from living skin established the term acid mantle - the skin's own protective shield that maintains a naturally acid pH. It is invisible to the eye but crucial to the overall wellbeing of skin. Chronic alkalization can throw this acid mantle out of balance, leading to inflammation, dermatitis, and atopic skin diseases. It is therefore no surprise, that skin pH shifts have been observed in various skin pathologies. It is also obvious that the pH in topically applied preparations may play an important role. Optimal pH and buffer capacity within topical preparations not only support stability of active ingredients and auxiliary materials, but may also increase absorption of the non-ionized species of an acidic or a basic active ingredient. They may even open up opportunities to modify and "correct" skin pH and hence accelerate barrier recovery and maintain or enhance barrier integrity. Further efforts are needed to standardize and improve pH measurements in biological media or pharmaceutical/cosmetic vehicles to increase and ensure quality, comparability, and relevance of research data. In this volume, we present a unique collection of papers that address past, present and future issues of the pH of healthy and diseased skin. It is hoped that this collection will foster future efforts in clinical and experimental skin research.

Skin Barrier Function

Skin Barrier Function PDF Author: T. Agner
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318055867
Category : Medical
Languages : en
Pages : 164

Book Description
Although a very fragile structure, the skin barrier is probably one of the most important organs of the body. Inward/out it is responsible for body integrity and outward/in for keeping microbes, chemicals, and allergens from penetrating the skin. Since the role of barrier integrity in atopic dermatitis and the relationship to filaggrin mutations was discovered a decade ago, research focus has been on the skin barrier, and numerous new publications have become available. This book is an interdisciplinary update offering a wide range of information on the subject. It covers new basic research on skin markers, including results on filaggrin and on methods for the assessment of the barrier function. Biological variation and aspects of skin barrier function restoration are discussed as well. Further sections are dedicated to clinical implications of skin barrier integrity, factors influencing the penetration of the skin, influence of wet work, and guidance for prevention and saving the barrier. Distinguished researchers have contributed to this book, providing a comprehensive and thorough overview of the skin barrier function. Researchers in the field, dermatologists, occupational physicians, and related industry will find this publication an essential source of information.

Sensitive Skin Syndrome

Sensitive Skin Syndrome PDF Author: Golara Honari
Publisher: CRC Press
ISBN: 1351647369
Category : Medical
Languages : en
Pages : 347

Book Description
Sensitive skin is a widely reported condition where there is subjective cutaneous hyper-reactivity to environmental factors. Progress has been made in many aspects of the background science that will help clinicians in their management of patients presenting with the condition. This new text sums up the advances in thinking on pathophysiology, classification, methods of investigation, and the different susceptibilities of different types of skin.

Disease Control Priorities in Developing Countries

Disease Control Priorities in Developing Countries PDF Author: Dean T. Jamison
Publisher: World Bank Publications
ISBN: 0821361805
Category : Medical
Languages : en
Pages : 1449

Book Description
Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.

The Church Leader's Counseling Resource Book

The Church Leader's Counseling Resource Book PDF Author: Cynthia Franklin Ph.D.
Publisher: Oxford University Press
ISBN: 9780199831531
Category : Religion
Languages : en
Pages : 528

Book Description
This all-in-one guide is designed to better equip clergy and the church leaders to meet their congregations' needs in a spiritually grounded and scientifically sound manner. Succinct, easy-to-read chapters summarize all a pastor needs to know about a given problem area, including its signs or symptoms, questions to ask, effective helping skills, and, most importantly, when to refer to a mental health professional. Synthesizing what research says about treatment approaches for mental health issues, this user-friendly reference is filled with guidelines, case scenarios, key points to remember, resources for further help, advice on integrating scripture and theology with the best available research, and tips on partnering with others to provide the best possible care for each church member. Each chapter is designed for quick lookup by problem area, empowering church leaders to understand and help meet the challenges facing the children, adults, families, and communities that they serve.

Current Problems in Dermatology

Current Problems in Dermatology PDF Author: J. W. H. Mali
Publisher:
ISBN: 9783805513807
Category : Dermatology
Languages : en
Pages : 194

Book Description


Handbook of Arsenic Toxicology

Handbook of Arsenic Toxicology PDF Author: Swaran Jeet Singh Flora
Publisher: Academic Press
ISBN: 0124199550
Category : Medical
Languages : en
Pages : 752

Book Description
Throughout history, arsenic has been used as an effective and lethal poison. Today, arsenic continues to present a real threat to human health all over the world, as it contaminates groundwater and food supplies. Handbook of Arsenic Toxicology presents the latest findings on arsenic, its chemistry, its sources and its acute and chronic effects on the environment and human health. The book takes readings systematically through the target organs, before detailing current preventative and counter measures. This reference enables readers to effectively assess the risks related to arsenic, and provide a comprehensive look at arsenic exposure, toxicity and toxicity prevention. Brings together current findings on the effects of arsenic on the environment and human health Includes state-of-the-art techniques in arsenic toxicokinetics, speciation and molecular mechanisms Provides all the information needed for effective risk assessment, prevention and countermeasure

Engineering

Engineering PDF Author: Unesco
Publisher: UNESCO
ISBN: 9231041568
Category : Technology & Engineering
Languages : en
Pages : 392

Book Description
This report reviews engineering's importance to human, economic, social and cultural development and in addressing the UN Millennium Development Goals. Engineering tends to be viewed as a national issue, but engineering knowledge, companies, conferences and journals, all demonstrate that it is as international as science. The report reviews the role of engineering in development, and covers issues including poverty reduction, sustainable development, climate change mitigation and adaptation. It presents the various fields of engineering around the world and is intended to identify issues and challenges facing engineering, promote better understanding of engineering and its role, and highlight ways of making engineering more attractive to young people, especially women.--Publisher's description.

Challenging Problems in Algebra

Challenging Problems in Algebra PDF Author: Alfred S. Posamentier
Publisher: Courier Corporation
ISBN: 0486131548
Category : Mathematics
Languages : en
Pages : 288

Book Description
Over 300 unusual problems, ranging from easy to difficult, involving equations and inequalities, Diophantine equations, number theory, quadratic equations, logarithms, more. Detailed solutions, as well as brief answers, for all problems are provided.

Homelessness, Health, and Human Needs

Homelessness, Health, and Human Needs PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309038324
Category : Medical
Languages : en
Pages : 257

Book Description
There have always been homeless people in the United States, but their plight has only recently stirred widespread public reaction and concern. Part of this new recognition stems from the problem's prevalence: the number of homeless individuals, while hard to pin down exactly, is rising. In light of this, Congress asked the Institute of Medicine to find out whether existing health care programs were ignoring the homeless or delivering care to them inefficiently. This book is the report prepared by a committee of experts who examined these problems through visits to city slums and impoverished rural areas, and through an analysis of papers written by leading scholars in the field.