Reaction Mechanisms in Organic Synthesis PDF Download

Author: Rakesh Kumar Parashar
Publisher: John Wiley & Sons
ISBN: 1118681266
Category : Science
Languages : en
Pages : 392

View

Book Description
Organic chemistry is a core part of the chemistry curricula, andadvanced levels texts often obscure the essential frameworkunderlying and uniting the vast numbers of reactions as a result ofthe high level of detail presented. The material in this book iscondensed into a manageable text of 350 pages and presented in aclear and logical fashion, focusing purely on the basics of thesubject without going through exhaustive detail or repetitiveexamples. The book aims to bridge the gap between undergraduateorganic chemistry textbooks and advanced level textbooks, beginningwith a basic introductory course and arranging the reactionmechanisms according to an ascending order of difficulty. As such,the author believes the book will be excellent primer for advancedpostgraduates Reaction Mechanisms in Organic Synthesis is written fromthe point of view of the synthetic organic chemist, enablingstudents and researchers to understand and expand on reactionscovered in foundation courses, and to apply them in a practicalcontext by designing syntheses. As a further aid to the practicalresearch student, the content is organized according to theconditions under which a reaction is executed rather than by thetypes of mechanisms. Particular emphasis is placed on controllingstereospecificity and regiospecificity. Topics covered include: Transition metal mediated carbon-carbon bond formationreactions Use of stabilized carbanions, ylides and enamines forcarbon-carbon bond formation reactions, Advanced level use of oxidation and reduction reagents insynthesis. As a modern text, this book stands out from its competitors dueto its comprehensive coverage of recently published research. Thebook contains specific examples from the latest literature,covering modern reactions and the latest procedural modifications.The focus on contemporary and synthetically useful reactionsensures that the contents are specifically relevant and attractiveto postgraduate students and industrial organic chemists.

Author: Laszlo Kurti
Publisher: Elsevier
ISBN: 0080575412
Category : Science
Languages : en
Pages : 864

View

Book Description
Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist. * The first reference work on named reactions to present colored schemes for easier understanding * 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples * An opening list of abbreviations includes both structures and chemical names * Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works * Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools * Extensive index quickly locates information using words found in text and drawings

Author: Kenneth A. Savin
Publisher: Academic Press
ISBN: 0124105092
Category : Science
Languages : en
Pages : 510

View

Book Description
Writing Reaction Mechanisms in Organic Chemistry, Third Edition, is a guide to understanding the movements of atoms and electrons in the reactions of organic molecules. Expanding on the successful book by Miller and Solomon, this new edition further enhances your understanding of reaction mechanisms in organic chemistry and shows that writing mechanisms is a practical method of applying knowledge of previously encountered reactions and reaction conditions to new reactions. The book has been extensively revised with new material including a completely new chapter on oxidation and reduction reactions including stereochemical reactions. It is also now illustrated with hundreds of colorful chemical structures to help you understand reaction processes more easily. The book also features new and extended problem sets and answers to help you understand the general principles and how to apply these to real applications. In addition, there are new information boxes throughout the text to provide useful background to reactions and the people behind the discovery of a reaction. This new edition will be of interest to students and research chemists who want to learn how to organize what may seem an overwhelming quantity of information into a set of simple general principles and guidelines for determining and describing organic reaction mechanisms. Extensively rewritten and reorganized with a completely new chapter on oxidation and reduction reactions including stereochemical reactions Essential for those who need to have mechanisms explained in greater detail than most organic chemistry textbooks provide Now illustrated with hundreds of colorful chemical structures to help you understand reaction processes more easily New and extended problem sets and answers to help you understand the general principles and how to apply this to real applications New information boxes throughout the text to provide useful background to reactions and the people behind the discovery of a reaction

Author: Robert B. Grossman
Publisher: Springer Science & Business Media
ISBN: 0387954686
Category : Science
Languages : en
Pages : 371

View

Book Description
Intended for students of intermediate organic chemistry, this text shows how to write a reasonable mechanism for an organic chemical transformation. The discussion is organized by types of mechanisms and the conditions under which the reaction is executed, rather than by the overall reaction as is the case in most textbooks. Each chapter discusses common mechanistic pathways and suggests practical tips for drawing them. Worked problems are included in the discussion of each mechanism, and "common error alerts" are scattered throughout the text to warn readers about pitfalls and misconceptions that bedevil students. Each chapter is capped by a large problem set.

Author: Roman Valiulin
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110608375
Category : Science
Languages : en
Pages : 249

View

Book Description
This book summarizes 100 essential mechanisms in organic chemistry ranging from classical such as the Reformatsky Reaction from 1887 to recently elucidated mechanism such as the copper(I)-catalyzed alkyne-azide cycloaddition. The reactions are easy to grasp, well-illustrated and underpinned with explanations and additional information.

Author: V. K. Ahluwalia
Publisher: Alpha Science Int'l Ltd.
ISBN: 9781842652367
Category : Religion
Languages : en
Pages : 672

View

Book Description
This book, written explicitly for graduate and postgraduate students of chemistry, provides an extensive coverage of various organic reaction and rearrangements with emphasis on there application in synthesis. A summary of oxidation and reduction of organic compounds is given in tabular form (correlation tables) for the convenience of students. The most commonly encountered reaction intermediates are dealt with. Applications of organic reagents illustrated with examples and problems at the end of each chapter will enable students to evaluate their understanding of the topic.

Author: Audrey Miller
Publisher: Elsevier
ISBN: 0080571247
Category : Science
Languages : en
Pages : 488

View

Book Description
Presentation is clear and instructive: students will learn to recognize that many of the reactions in organic chemistry are closely related and not independent facts needing unrelated memorization. The book emphasizes that derivation of a mechanism is not a theoretical procedure, but a means of applying knowledge of other similar reactions and reaction conditions to the new reaction. n Brief summaries of required basic knowledge of organic structure, bonding, stereochemistry, resonance, tautomerism, and molecular orbital theory n Definitions of essential terms n Typing and classification of reactions n Hints (rules) for deriving the most likely mechanism for any reaction

Author: Richard A. Jackson
Publisher: Royal Society of Chemistry
ISBN: 9780854046423
Category : Education
Languages : en
Pages : 212

View

Book Description
An increasing knowledge and understanding of organic reaction mechanisms has been a major factor in the rapid advance of organic chemistry, biochemistry and pharmacology in the last century. It therefore forms a vital part of today's chemistry courses. Mechanisms in Organic Reactions helps students to make sensible proposals for the mechanisms of particular organic reactions, and then how to distinguish between different possible mechanisms. Techniques for this include product studies, kinetics, and the identification of intermediates. Three chapters on intermediates discuss likely points of attack on molecules by anions, radicals and cations, and the important role of acid- and base-catalysed reactions and radical chain reactions. The prediction of reaction rates and the effects of structural changes on reaction rate are also covered. It concludes with a discussion of molecular reactions, both thermal and photochemical - reactions which provide deep and beautiful insights into the reasons why some reactions go and others do not, and why the majority of real-life reactions involve multi-step processes. The book provides both illuminating insights into fundamental chemistry, and also practical value for students who will go on to teach, research, or be involved in other scientific roles (administration, policy making or journalism). Ideal for the needs of undergraduate chemistry students, Tutorial Chemistry Texts is a major series consisting of short, single topic or modular texts concentrating on the fundamental areas of chemistry taught in undergraduate science courses. Each book provides a concise account of the basic principles underlying a given subject, embodying an independent-learning philosophy and including worked examples.

Author: Reinhard Bruckner
Publisher: Springer Science & Business Media
ISBN: 3642036503
Category : Science
Languages : en
Pages : 873

View

Book Description
This English edition of a best-selling and award-winning German textbook Reaction Mechanisms: Organic Reactions · Stereochemistry · Modern Synthetic Methods is aimed at those who desire to learn organic chemistry through an approach that is facile to understand and easily committed to memory. Michael Harmata, Norman Rabjohn Distinguished Professor of Organic Chemistry (University of Missouri) surveyed the accuracy of the translation, made certain contributions, and above all adapted its rationalizations to those prevalent in the organic chemistry community in the English-speaking world. Throughout the book fundamental and advanced reaction mechanisms are presented with meticulous precision. The systematic use of red "electron-pushing arrows" allows students to follow each transformation elementary step by elementary step. Mechanisms are not only presented in the traditional contexts of rate laws and substituent effects but, whenever possible, are illustrated using practical, useful and state-of-the-art reactions. The abundance of stereoselective reactions included in the treatise makes the reader familiar with key concepts of stereochemistry. The fundamental topics of the book address the needs of upper-level undergraduate students, while its advanced sections are intended for graduate-level audiences. Accordingly, this book is an essential learning tool for students and a unique addition to the reference desk of practicing organic chemists, who as life-long learners desire to keep abreast of both fundamental and applied aspects of our science. In addition, it will well serve ambitious students in chemistry-related fields such as biochemistry, medicinal chemistry and pharmaceutical chemistry. From the reviews: "Professor Bruckner has further refined his already masterful synthetic organic chemistry classic; the additions are seamless and the text retains the magnificent clarity, rigour and precision which were the hallmark of previous editions. The strength of the book stems from Professor Bruckner’s ability to provide lucid explanations based on a deep understanding of physical organic chemistry and to limit discussion to very carefully selected reaction classes illuminated by exquisitely pertinent examples, often from the recent literature. The panoply of organic synthesis is analysed and dissected according to fundamental structural, orbital, kinetic and thermodynamic principles with an effortless coherence that yields great insight and never over-simplifies. The perfect source text for advanced Undergraduate and Masters/PhD students who want to understand, in depth, the art of synthesis ." Alan C. Spivey, Imperial College London "Bruckner’s ‘Organic Mechanisms’ accurately reflects the way practicing organic chemists think and speak about organic reactions. The figures are beautifully drawn and show the way organic chemists graphically depict reactions. It uses a combination of basic valence bond pictures with more sophisticated molecular orbital treatments. It handles mechanisms both from the "electron pushing perspective" and from a kinetic and energetic view. The book will be very useful to new US graduate students and will help bring them to the level of sophistication needed to be serious researchers in organic chemistry." Charles P. Casey, University of Wisconsin-Madison "This is an excellent advanced organic chemistry textbook that provides a key resource for students and teachers alike." Mark Rizzacasa, University of Melbourne, Australia.

Author: Bradford P. Mundy
Publisher: John Wiley & Sons
ISBN: 0471739863
Category : Science
Languages : en
Pages : 900

View

Book Description
This Second Edition is the premier name resource in the field. It provides a handy resource for navigating the web of named reactions and reagents. Reactions and reagents are listed alphabetically, followed by relevant mechanisms, experimental data (including yields where available), and references to the primary literature. The text also includes three indices based on reagents and reactions, starting materials, and desired products. Organic chemistry professors, graduate students, and undergraduates, as well as chemists working in industrial, government, and other laboratories, will all find this book to be an invaluable reference.