Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Regenerating the Heart PDF full book. Access full book title Regenerating the Heart by Ira S. Cohen. Download full books in PDF and EPUB format.
Author: Ira S. Cohen Publisher: Springer Science & Business Media ISBN: 1617790214 Category : Science Languages : en Pages : 555
Book Description
Medical research made huge strides in treating heart disease in the 20th century, from drug-eluding stents to automatic internal defibrillators. Public awareness of the dangers of heart disease has never been more pervasive. Now, though, ten years into a new millennium, scientists are gearing up for the next great challenges in tackling this pervasive condition. Cell therapy is going to be a key weapon in the fight against heart disease. It has the potential to address many cardiovascular conditions. From heart failure to atrioventricular nodal dysfunction, the young but promising field of cell therapy is set to play a significant role in developing the cures that the upcoming decades of hard work will yield. Regenerating the Heart: Stem Cells and the Cardiovascular System organizes the field into a digestible body of knowledge. Its four sections cover mechanical regeneration, electrical regeneration, cardiac tissues and in vivo stem cell therapies. An array of talented researchers share the fruits of their labors, with chapters covering such crucial issues as the cardiogenic potential of varying stem cell types, the ways in which they might be used to tackle arrhythmias, their possible application to biological replacements for cardiac tissues such as valves, and the varying approaches used in the in vivo evaluation of stem cell therapies, including methods of delivering stem cells to the myocardium. This comprehensive survey of an area of research with such exciting potential is an invaluable resource both for veteran stem cell researchers who need to monitor fresh developments, and for newly minted investigators seeking inspirational examples.
Author: Ira S. Cohen Publisher: Springer Science & Business Media ISBN: 1617790214 Category : Science Languages : en Pages : 555
Book Description
Medical research made huge strides in treating heart disease in the 20th century, from drug-eluding stents to automatic internal defibrillators. Public awareness of the dangers of heart disease has never been more pervasive. Now, though, ten years into a new millennium, scientists are gearing up for the next great challenges in tackling this pervasive condition. Cell therapy is going to be a key weapon in the fight against heart disease. It has the potential to address many cardiovascular conditions. From heart failure to atrioventricular nodal dysfunction, the young but promising field of cell therapy is set to play a significant role in developing the cures that the upcoming decades of hard work will yield. Regenerating the Heart: Stem Cells and the Cardiovascular System organizes the field into a digestible body of knowledge. Its four sections cover mechanical regeneration, electrical regeneration, cardiac tissues and in vivo stem cell therapies. An array of talented researchers share the fruits of their labors, with chapters covering such crucial issues as the cardiogenic potential of varying stem cell types, the ways in which they might be used to tackle arrhythmias, their possible application to biological replacements for cardiac tissues such as valves, and the varying approaches used in the in vivo evaluation of stem cell therapies, including methods of delivering stem cells to the myocardium. This comprehensive survey of an area of research with such exciting potential is an invaluable resource both for veteran stem cell researchers who need to monitor fresh developments, and for newly minted investigators seeking inspirational examples.
Author: Masaki Ieda Publisher: Springer ISBN: 3319561065 Category : Medical Languages : en Pages : 274
Book Description
This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.
Author: Milica Radisic Publisher: Humana Press ISBN: 9781493910465 Category : Science Languages : en Pages : 0
Book Description
Cardiac Tissue Engineering: Methods and Protocols presents a collection of protocols on cardiac tissue engineering from pioneering and leading researchers around the globe. These include methods and protocols for cell preparation, biomaterial preparation, cell seeding, and cultivation in various systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cardiac Tissue Engineering: Methods and Protocols highlights the major techniques, both experimental and computational, for the study of cardiovascular tissue engineering.
Author: Gianfranco Sinagra Publisher: Springer ISBN: 303013864X Category : Medical Languages : en Pages : 241
Book Description
This open access book presents a comprehensive overview of dilated cardiomyopathy, providing readers with practical guidelines for its clinical management. The first part of the book analyzes in detail the disease’s pathophysiology, its diagnostic work up as well as the prognostic stratification, and illustrates the role of genetics and gene-environment interaction. The second part presents current and future treatment options, highlighting the importance of long-term and individualized treatments and follow-up. Furthermore, it discusses open issues, such as the apparent healing phenomenon, the early prognosis of arrhythmic events or the use of genetic testing in clinical practice. Offering a multidisciplinary approach for optimizing the clinical management of DCM, this book is an invaluable aid not only for the clinical cardiologists, but for all physicians involved in the care of this challenging disease.
Author: Chandra P. Sharma Publisher: Elsevier ISBN: 1845699807 Category : Medical Languages : en Pages : 424
Book Description
Biointegration is essential for the successful performance of implanted materials and devices within the human body. With an increasing number and wide range of implant procedures being performed, it is critical that materials scientists and engineers effectively design implant materials which will create a positive biological and mechanical response with the host tissue. Biointegration of medical implant materials provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. Part one discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering and vascular grafts. Part two then reviews particular techniques in drug delivery including inorganic nanoparticles for targeted drug delivery and alginate based drug delivery devices. Part three covers design considerations with coverage of themes such as biocompatibility of materials and its relevance to drug delivery and tissue engineering, mechanisms of failure of medical implants during long term use and rapid prototyping in biomedical engineering. With its distinguished editor and team of international contributors, Biointegration of medical implant materials: science and design is a standard reference for medical materials scientists and engineers in industry and the academic sector. Provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration Discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, vascular grafts and replacement materials for facial reconstruction Reviews particular techniques in drug delivery featuring inorganic nanoparticles and functionalized nanoparticles for targeted drug delivery
Author: Paul Hawken Publisher: Penguin ISBN: 052550849X Category : Science Languages : en Pages : 257
Book Description
A radically new understanding of and practical approach to climate change by noted environmentalist Paul Hawken, creator of the New York Times bestseller Drawdown Regeneration offers a visionary new approach to climate change, one that weaves justice, climate, biodiversity, equity, and human dignity into a seamless tapestry of action, policy, and transformation that can end the climate crisis in one generation. It is the first book to describe and define the burgeoning regeneration movement spreading rapidly throughout the world. Regeneration describes how an inclusive movement can engage the majority of humanity to save the world from the threat of global warming, with climate solutions that directly serve our children, the poor, and the excluded. This means we must address current human needs, not future existential threats, real as they are, with initiatives that include but go well beyond solar, electric vehicles, and tree planting to include such solutions as the fifteen-minute city, bioregions, azolla fern, food localization, fire ecology, decommodification, forests as farms, and the number one solution for the world: electrifying everything. Paul Hawken and the nonprofit Regeneration Organization are launching a series of initiatives to accompany the book, including a streaming video series, curriculum, podcasts, teaching videos, and climate action software. Regeneration is the inspiring and necessary guide to inform the rapidly spreading climate movement.
Author: Anthony Atala Publisher: Academic Press ISBN: 9780123814234 Category : Science Languages : en Pages : 1202
Book Description
Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs
Author: William C. Claycomb Publisher: ISBN: Category : Blood-vessels Languages : en Pages : 560
Book Description
Mammalian cardiac muscle, unlike that in amphibians, reptiles and the mammalian atrium, cannot regenerate after injury, and the mechanism for the irreversible blockage of mitosis in these monocytes during early development is still not understood. This book attempts to study the mechanisms that control the cardiac muscle cell cycle so that treatments to initiate repair of the myocardium can be designed. An ideal model would allow study of cardiac muscle cells in the intact heart in the biochemical state they were in during foetal growth, when they were actively dividing. This volume gathers the most current information dealing with the regenerative potential of cardiac muscle in the vertebrate heart.
Author: Chandra P. Sharma Publisher: Academic Press ISBN: 0128240652 Category : Science Languages : en Pages : 724
Book Description
Tissue Engineering: Current Status and Challenges bridges the gap between biomedical scientists and clinical practitioners. The work reviews the history of tissue engineering, covers the basics required for the beginner, and inspires those in the field toward future research and application emerging in this fast-moving field. Written by global experts in the field for those studying and researching tissue engineering, the book reviews regenerative technologies, stem cell research and regeneration of organs. It then moves to soft tissue engineering (heart, vascular, muscle and 3D scaffolding and printing), hard tissue engineering (bone, dental myocardial and musculoskeletal) and translational avenues in the field. Introduces readers to the history and benefits of tissue engineering Includes coverage of new techniques and technologies, such as nanotechnology and nanoengineering Presents concepts, ideology and theories which form the foundation for next-generation tissue engineering
Author: Ira S. Cohen
Author: Ira S. Cohen
Author: Masaki Ieda
Author: 
Author: Milica Radisic
Author: Gianfranco Sinagra
Author: Chandra P. Sharma
Author: Paul Hawken
Author: Anthony Atala
Author: William C. Claycomb
Author: Chandra P. Sharma