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Author: James R. Valcourt Publisher: Bloomsbury Publishing USA ISBN: 1632860317 Category : Science Languages : en Pages : 289
Book Description
A brilliant young scientist introduces us to the fascinating field that is changing our understanding of how the body works and the way we can approach healing. SYSTEMATIC is the first book to introduce general readers to systems biology, which is improving medical treatments and our understanding of living things. In traditional bottom-up biology, a biologist might spend years studying how a single protein works, but systems biology studies how networks of those proteins work together--how they promote health and how to remedy the situation when the system isn't functioning properly. Breakthroughs in systems biology became possible only when powerful computer technology enabled researchers to process massive amounts of data to study complete systems, and has led to progress in the study of gene regulation and inheritance, cancer drugs personalized to an individual's genetically unique tumor, insights into how the brain works, and the discovery that the bacteria and other microbes that live in the gut may drive malnutrition and obesity. Systems biology is allowing us to understand more complex phenomena than ever before. In accessible prose, SYSTEMATIC sheds light not only on how systems within the body work, but also on how research is yielding new kinds of remedies that enhance and harness the body's own defenses.
Author: James R. Valcourt Publisher: Bloomsbury Publishing USA ISBN: 1632860317 Category : Science Languages : en Pages : 289
Book Description
A brilliant young scientist introduces us to the fascinating field that is changing our understanding of how the body works and the way we can approach healing. SYSTEMATIC is the first book to introduce general readers to systems biology, which is improving medical treatments and our understanding of living things. In traditional bottom-up biology, a biologist might spend years studying how a single protein works, but systems biology studies how networks of those proteins work together--how they promote health and how to remedy the situation when the system isn't functioning properly. Breakthroughs in systems biology became possible only when powerful computer technology enabled researchers to process massive amounts of data to study complete systems, and has led to progress in the study of gene regulation and inheritance, cancer drugs personalized to an individual's genetically unique tumor, insights into how the brain works, and the discovery that the bacteria and other microbes that live in the gut may drive malnutrition and obesity. Systems biology is allowing us to understand more complex phenomena than ever before. In accessible prose, SYSTEMATIC sheds light not only on how systems within the body work, but also on how research is yielding new kinds of remedies that enhance and harness the body's own defenses.
Author: Margaret J. Foster Publisher: Rowman & Littlefield ISBN: 1442277025 Category : Language Arts & Disciplines Languages : en Pages : 242
Book Description
Here is a complete guide for librarians seeking to launch or refine their systematic review services. Conducting searches for systematic reviews goes beyond expert searching and requires an understanding of the entire process of the systematic review. Just as expert searching is not fully mastered by the end of a library degree, mastering the systematic review process takes a great deal of time and practice. Attending workshops and webinars can introduce the topic, but application of the knowledge through practice is required. Running a systematic review service is complicated and requires constant updating and evaluation with new standards, more efficient methods, and improved reporting guidelines. After a brief introduction to systematic reviews, the book guides librarians in defining and marketing their services, covering topics such as when it is appropriate to ask for co-authorship and how to reach out to stakeholders. Next, it addresses developing documentation and conducting the reference interview. Standards specific to systematic reviews, including PRISMA, Institute of Medicine, and Cochrane Collaboration, are discussed. Search strategy techniques, including choosing databases, harvesting search terms, selecting filters, and searching for grey literature are detailed. Data management and critical appraisal are covered in detail. Finally, the best practices for reporting the findings of systematic reviews are highlighted. Experts with experience in both systematic reviews and librarianship, including the editors of the book, contributed to the chapters. Each step (or piece) of the review process (Planning the review, Identifying the studies, Evaluating studies, Collecting and combining data, Explaining the results, and Summarizing the review into a report), are covered with emphasis on information roles. The book is for any librarian interested in conducting reviews or assisting others with reviews. It has several applications: for training librarians new to systematic reviews, for those developing a new systematic review service, for those wanting to establish protocols for a current service, and as a reference for those conducting reviews or running a service. Participating in systematic reviews is a new frontier of librarianship, in which librarians can truly become research partners with our patrons, instead of merely providing access to resources and services.
Author: Alice M. Rivlin Publisher: Brookings Institution Press ISBN: 9780815720584 Category : Political Science Languages : en Pages : 170
Book Description
How can we identify who benefits from government programs aimed at solving our social problem and who pays for them? With so many problems, how can we allocate scarce funds to promote the maximum well-being of our citizens? In this book, originally presented as the third series of H. Rowan Gaither Lectures in Systems Science at the University of California (Berkeley). Alice M. Rivlin examines the contributions that systematic analysis has made to decisionmaking in the government's "social action" programs—education, health, manpower training, and income maintenance. Drawing on her own experience in government, Mrs. Rivlin indicates where the analysts have been helpful in finding solutions and where—because of inadequate data or methods—they have been no help at all. Mrs. Rivlin concludes by urging the widespread implementation of social experimentation and acceptability by the federal government. The first in such a way as to permit valid conclusions about their effectiveness; the second would encourage the adoption of better ways of delivering services by making those who administer programs responsive to their clients. Underlying both is the requirement from comprehensive, reliable performance measures.
Author: Adedeji B. Badiru Publisher: CRC Press ISBN: 1351648918 Category : Technology & Engineering Languages : en Pages : 429
Book Description
Work is all around us and permeates everything we do and everyday activities. Not all work is justified, not all work is properly designed, or evaluated accurately, or integrated. A systems model will make work more achievable through better management. Work is defined as a process of performing a defined task or activity, such as research, development, operations, maintenance, repair, assembly, production, and so on. Very little is written on how to design, evaluate, justify, and integrate work. Using a comprehensive systems approach, this book facilitates a better understanding of work for the purpose of making it more effective and rewarding.
Author: Andrew Booth Publisher: SAGE ISBN: 1473952816 Category : Reference Languages : en Pages : 376
Book Description
Showing you how to take a structured and organized approach to a wide range of literature review types, this book helps you to choose which approach is right for your research. Packed with constructive tools, examples, case studies and hands-on exercises, the book covers the full range of literature review techniques. New to This Edition: Full re-organization takes you step-by-step through the process from beginning to end New chapter showing you how to choose the right method for your project Practical guidance on integrating qualitative and quantitative data New coverage of rapid reviews Comprehensive inclusion of literature review tools, including concept analysis, scoping and mapping With an emphasis on the practical skills, this guide is essential for any student or researcher needing to get from first steps to a successful literature review.
Author: Sanjay Patole Publisher: Springer Nature ISBN: 3030719219 Category : Medical Languages : en Pages : 189
Book Description
Evidence based medicine is at the core of modern medicine. It involves the integration of individual clinical expertise with the best available clinical evidence from systematic research and patient's values and expectations. Systematic reviews offer a summary of the best available evidence. They are the most reliable and comprehensive statement about what works. Written by clinical academics from Australia, UK, USA, and Switzerland, this contributed volume introduces the readers to the principles and practice of systematic reviews and meta-analysis. It covers the various steps involved in systematic reviews including development of a focused question and the strategy for conducting a comprehensive literature search, identifying studies addressing the underlying question, assessment of heterogeneity and the risk of bias in the included studies, data extraction, and the approach to meta-analysis. Crucial issues such as selecting the model for meta-analysis, generating and interpreting forest plots, assessing the risk of publication bias, cautions in the interpretation of subgroup and sensitivity analyses, rating certainty of the evidence using GRADE guideline, and standardized reporting of meta-analysis (PRISMA) are covered in detail. Every attempt is made to keep the narrative simple and clear. Mathematical formulae are avoided as much as possible. While the focus of this book is on systematic reviews and meta-analyses of randomised controlled trials (RCTs), the gold standard of clinical research, the essentials of systematic reviews of non-RCTs, diagnostic test accuracy studies, animal studies, individual participant data meta-analysis, and network meta-analysis are also covered. Readers from all faculties of medicine will enjoy this comprehensive and reader friendly book to understand the principles and practice of systematic reviews and meta-analysis for guiding their clinical practice and research.
Author: David Gough Publisher: SAGE ISBN: 1473968216 Category : Education Languages : en Pages : 353
Book Description
Focused on actively using systematic review as method, this book provides clear, step-by-step advice on the logic and processes of systematic reviewing. Stressing the importance of precision and accuracy, this new edition carefully balances a need for insightful theory with real-world pragmatism; it introduces a wide range of cutting-edge approaches to research synthesis including text mining, living reviews and new ideas in mixed methods reviews such as qualitative comparative analysis. The book also includes: A new chapter on statistical synthesis Coverage of computer-assisted methods and relevant software Expanded sections on data extraction and management A guide to working with many different types of data including longitudinal and panel. Packed with examples from across the social sciences, this book helps students and researchers alike in turning systematic reviews into recommendations for policy and practice.
Author: Cheryl Holly, EdD, RN, ANEF, FNAP Publisher: Springer Publishing Company ISBN: 0826152260 Category : Medical Languages : en Pages : 599
Book Description
A two-time AJN Book of the Year Award winner and a 2013 Doody Core Title! This distinguished text provides top-tier guidance for advanced practice nurses on how to perform a comprehensive systematic review of available research to inform scholarly work, particularly in DNP and PhD programs. With a strategic focus on the search process and assessing the quality of the evidence, this text presents, clearly and comprehensively, all of the knowledge and skills necessary to conduct a foundational CSR in eight concrete steps. This text examines how to write a CSR proposal, final report, and a policy brief based on systematic review findings. Two finished proposals and two completed systematic reviews demonstrate each step of the process from start to finish. Additionally, the text covers software used in research queries and provides helpful strategies for effectively using the search function when seeking information. The Third Edition offers four new chapters with incisive recommendations for performing a CSR and addressing new ways CSR is being implemented in today’s healthcare environment. It describes the latest methodological advances, including living systematic reviews and dominance scores for economic review. Two complete CSRs along with new and updated examples throughout the book further aid readers in their pursuit of excellence in scholarly work. New to the Third Edition: New Chapters: How to choose the right critical appraisal tool Writing the final report and disseminating the results of systematic reviews Disseminating results with how to write a policy brief and/or press release on CSR results Example of a meta-analysis using GRADE Offers increased focus on dissemination Includes new and updated examples reflecting latest trends in nursing scholarly work Key Features: Provides the knowledge and skills necessary to conduct a CSR from start to finish Teaches readers how to conduct high-quality systematic reviews Instructs readers on pertinent resources and methods for optimal library-related systematic review research efforts Describes how to best search research databases to facilitate scholarly work Includes objectives, summary points, end-of-chapter exercises, discussion questions, suggested reading, and references to enhance understanding
Author: Paul Levay Publisher: Facet Publishing ISBN: 1783303735 Category : Language Arts & Disciplines Languages : en Pages : 352
Book Description
In resource poor, cost saving times, this book provides practical advice on new methods and technologies involved in systematic searching and explores the role of information professionals in delivering these changes The editors bring together expert international practitioners and researchers to highlight the latest thinking on systematic searching. Beginning by looking at the methods and techniques underlying systematic searching, the book then examines the current challenges and the potential solutions to more effective searching in detail, before considering the role of the information specialist as an expert searcher. Systematic Searching blends theory and practice and takes into account different approaches to information retrieval with a special focus being given to searching for complex topics in a health-related environment. The book does not presume an in-depth prior knowledge or experience of systematic searching and includes case studies, practical examples and ideas for further research and reading. The book is divided into three parts: Methods covers theoretical approaches to evidence synthesis and the implications that these have for the search process, including searching for complex topics and choosing the right sources. Technology examines new technologies for retrieving evidence and how these are leading to new directions in information retrieval and evidence synthesis. People considers the future of the information specialist as an expert searcher and explores how information professionals can develop their skills in searching, communication and collaboration to ensure that information retrieval practice is, and remains, evidence-based. Systematic Searching will be essential reading for library and information service providers and information specialists, particularly those in a health-related environment. It will also be of interest to students of library and information science, systematic reviewers, researchers and practitioners conducting complex searches in settings including social care, education and criminal justice.
Author: James R. Valcourt
Author: James R. Valcourt
Author: Margaret J. Foster
Author: Alice M. Rivlin
Author: Adedeji B. Badiru
Author: Andrew Booth
Author: Cheryl Holly
Author: Sanjay Patole
Author: David Gough
Author: Cheryl Holly, EdD, RN, ANEF, FNAP
Author: Paul Levay