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Author: Ernst J. M. Helmreich Publisher: Oxford University Press, USA ISBN: 9780198508205 Category : Language Arts & Disciplines Languages : en Pages : 372
Book Description
A comprehensive study of the principles of cell signalling, concentrating on the structural and mechanistic aspects. The book is divided into four parts describing the machinery of signal transduction, the implementation of the signalling cascades focussing on the effect on gene transcription, the globular cellular regulatory programs, and the loss of regulatory control and its consequences with repsect to the molecular basis of cancer. There are well over 200 figures, many in 3-D representations.
Author: Ernst J. M. Helmreich Publisher: Oxford University Press, USA ISBN: 9780198508205 Category : Language Arts & Disciplines Languages : en Pages : 372
Book Description
A comprehensive study of the principles of cell signalling, concentrating on the structural and mechanistic aspects. The book is divided into four parts describing the machinery of signal transduction, the implementation of the signalling cascades focussing on the effect on gene transcription, the globular cellular regulatory programs, and the loss of regulatory control and its consequences with repsect to the molecular basis of cancer. There are well over 200 figures, many in 3-D representations.
Author: Ralph A. Bradshaw Publisher: Academic Press ISBN: 0080920918 Category : Science Languages : en Pages : 3048
Book Description
Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Handbook of Cell Signaling, 2/e will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. Contains over 350 chapters of comprehensive coverage on cell signaling Includes discussion on topics from ligand/receptor interactions to organ/organism responses Provides user-friendly, well-illustrated, reputable content by experts in the field
Author: John Hancock Publisher: Oxford University Press ISBN: 0199232105 Category : Education Languages : en Pages : 364
Book Description
'Cell Signalling' presents a carefully structured introduction to this subject, introducing those conserved features which underlie many different extra-and intracellular signalling systems.
Author: Gerhard Krauss Publisher: John Wiley & Sons ISBN: 3527605762 Category : Science Languages : de Pages : 558
Book Description
This all-new edition of a classic text has been thoroughly revised to keep pace with the rapid progress in signal transduction research. With didactic skill and clarity the author relates the observed biological phenomena to the underlying biochemical processes. Directed to advanced students, teachers, and researchers in biochemistry and molecular biology, this book describes the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis. "Provides a comprehensive account of cell signaling and signal transduction and, where possible, explains these processes at the molecular level" (Angewandte Chemie) "The clear and didactic presentation makes it a textbook very useful for students and researchers not familiar with all aspects of cell regulation." (Biochemistry) "This book is actually two books: Regulation and Signal Transduction." (Drug Research)
Author: John Nelson Publisher: John Wiley & Sons ISBN: 0470723734 Category : Science Languages : en Pages : 416
Book Description
"This book contains extremely detailed and informative content on structure and function of ligands, receptors, and signalling intermediates plus interactions ... the extent of detail and appropriate referencing is impressive." –Microbiology Today, July 2009 "A very well-written book suitable for use as a reference or textbook for an undergraduate subject in cell signalling. For researchers interested in the molecular basis of cell signalling and how aberrant regulation of cell signalling proteins causes diseases, this is an excellent resource of biochemical and structural information." –Australian Biochemist, August 2009 "From basics to details, this is an elegantly written and carefully edited book. The chapters on cell cycle control and oncogenesis are particularly fascinating and valuable to biomedical research. This is the book to have if you are interested in molecular mechanisms of signal transduction. It is a great introduction to the literature that will be welcomed by students and experts alike." –Doody's, January 2009 This text is a concise and accessible introduction to the dynamic but complex field of signal transduction. Rather than simply cataloguing all signalling molecules and delineating every known pathway, this book aims to break signalling down into common elements and activities – the ‘nuts and bolts’ of cellular information exchange. With an emphasis on clarity of presentation throughout, the book teaches the basic principles focusing on a mature core of knowledge, providing students with a foundation of learning in this complex and potentially confusing subject. It also addresses the issue of variation in the numbering of key amino acids as well as featuring interaction with RasMol software, and exercises to aid understanding. An accessible introduction to the complex field of cell signalling Interacts with RasMol software – freely downloadable for viewing structures in 3D Includes exercises and clear instructions in the use of RasMol Well illustrated in full colour throughout Structure and Function in Cell Signalling is an invaluable resource to students across a range of life science degree programmes including biochemistry, cell and molecular biology, physiology, biomedicine and oncology. This book provides a clear, accessible introduction to this rapidly expanding field.
Author: Wendell Lim Publisher: Taylor & Francis ISBN: 1317573625 Category : Science Languages : en Pages : 412
Book Description
Cell Signaling presents the principles and components that underlie all known signaling processes. It provides undergraduate and graduate students the conceptual tools needed to make sense of the dizzying array of pathways used by the cell to communicate. By emphasizing the common design principles, components, and logic that drives all signa
Author: Friedrich Marks Publisher: Garland Science ISBN: 1351677217 Category : Medical Languages : en Pages : 982
Book Description
Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.
Author: James Ferrell Publisher: Garland Science ISBN: 1000430731 Category : Science Languages : en Pages : 285
Book Description
How can we understand the complexity of genes, RNAs, and proteins and the associated regulatory networks? One approach is to look for recurring types of dynamical behavior. Mathematical models prove to be useful, especially models coming from theories of biochemical reactions such as ordinary differential equation models. Clever, careful experiments test these models and their basis in specific theories. This textbook aims to provide advanced students with the tools and insights needed to carry out studies of signal transduction drawing on modeling, theory, and experimentation. Early chapters summarize the basic building blocks of signaling systems: binding/dissociation, synthesis/destruction, and activation/inactivation. Subsequent chapters introduce various basic circuit devices: amplifiers, stabilizers, pulse generators, switches, stochastic spike generators, and oscillators. All chapters consistently use approaches and concepts from chemical kinetics and nonlinear dynamics, including rate-balance analysis, phase plane analysis, nullclines, linear stability analysis, stable nodes, saddles, unstable nodes, stable and unstable spirals, and bifurcations. This textbook seeks to provide quantitatively inclined biologists and biologically inclined physicists with the tools and insights needed to apply modeling and theory to interesting biological processes. Key Features: Full-color illustration program with diagrams to help illuminate the concepts Enables the reader to apply modeling and theory to the biological processes Further Reading for each chapter High-quality figures available for instructors to download
Author: Yasushi Sako Publisher: Springer Science & Business Media ISBN: 904819864X Category : Medical Languages : en Pages : 335
Book Description
This book encompasses the exciting developments and challenges in the fast-moving and rapidly expanding research field of single-molecule kinetic analysis of cell signaling that promises to be one of the most significant and exciting areas of biological research for the foreseeable future. Cell signaling is carried out by complicated reaction networks of macromolecules, and single-molecule analyses has already demonstrated its power to unravel complex reaction dynamics in purified systems. To date, most of the published research in the field of single-molecule processes in cells, focus on the dynamic properties (translational movements of the centre of mass) of biological molecules. However, we hope that this book presents as many kinetic analyses of cell signaling as possible. Although single-molecule kinetic analysis of cellular systems is a relatively young field when compared with the analysis of single-molecule movements in cells, this type of analysis is highly important because it directly relates to the molecular functions that control cellular behavior and in the future, single-molecule kinetic analysis will be largely directed towards cellular systems. Thus, we hope that this book will be of interest to all those working in the fields of molecular and cell biology, as well as biophysics and biochemistry.
Author: Ernst J. M. Helmreich
Author: Ernst J. M. Helmreich
Author: Ralph A. Bradshaw
Author: John Hancock
Author: Gerhard Krauss
Author: John Nelson
Author: Wendell Lim
Author: Friedrich Marks
Author: James Ferrell
Author: Yasushi Sako
Author: Bruce Alberts