Author: C. Fest
Publisher: Springer Science & Business Media
ISBN: 3642684416
Category : Technology & Engineering
Languages : en
Pages : 369
Book Description
Rapid progress in the field of organophosphate compounds has made this new edition necessary. Particular attention has been paid to new developments in biologically active products as this is probably of greatest interest to practical chemists. I have therefore updated the chapter on chemistry and, in connection with this, rewritten the chapter on metabolism. I should especially like to thank Professor Dr. HELLMUT HOFFMANN for his constant encouragement and interest in my work and for many fruitful discus sions. The co-author to the 1st edition, Dr. KARL-JULIUS SCHMIDT, died suddenly on November 21, 1980. I treasure the memory of a valued colleague of many years standing. Elberfeld, January 1982 CHRISTA FEST VII Preface to the First Edition Our intention has been to provide a short introduction to the chemistry and mode of action of insecticidal phosphoric acid compounds, with particular ref erence to the relationship between structure and activity. The yearly produc tion of these pesticides is now approaching 100,000 tons and thus offers an im portant example of applied research. If, however, one examines the historical development of these compounds, it is apparent that this was preceded by a hundred years of pure chemistry of phosphorus.
The Chemistry of Organophosphorus Pesticides
Author: C. Fest
Publisher: Springer Science & Business Media
ISBN: 3642684416
Category : Technology & Engineering
Languages : en
Pages : 369
Book Description
Rapid progress in the field of organophosphate compounds has made this new edition necessary. Particular attention has been paid to new developments in biologically active products as this is probably of greatest interest to practical chemists. I have therefore updated the chapter on chemistry and, in connection with this, rewritten the chapter on metabolism. I should especially like to thank Professor Dr. HELLMUT HOFFMANN for his constant encouragement and interest in my work and for many fruitful discus sions. The co-author to the 1st edition, Dr. KARL-JULIUS SCHMIDT, died suddenly on November 21, 1980. I treasure the memory of a valued colleague of many years standing. Elberfeld, January 1982 CHRISTA FEST VII Preface to the First Edition Our intention has been to provide a short introduction to the chemistry and mode of action of insecticidal phosphoric acid compounds, with particular ref erence to the relationship between structure and activity. The yearly produc tion of these pesticides is now approaching 100,000 tons and thus offers an im portant example of applied research. If, however, one examines the historical development of these compounds, it is apparent that this was preceded by a hundred years of pure chemistry of phosphorus.
Publisher: Springer Science & Business Media
ISBN: 3642684416
Category : Technology & Engineering
Languages : en
Pages : 369
Book Description
Rapid progress in the field of organophosphate compounds has made this new edition necessary. Particular attention has been paid to new developments in biologically active products as this is probably of greatest interest to practical chemists. I have therefore updated the chapter on chemistry and, in connection with this, rewritten the chapter on metabolism. I should especially like to thank Professor Dr. HELLMUT HOFFMANN for his constant encouragement and interest in my work and for many fruitful discus sions. The co-author to the 1st edition, Dr. KARL-JULIUS SCHMIDT, died suddenly on November 21, 1980. I treasure the memory of a valued colleague of many years standing. Elberfeld, January 1982 CHRISTA FEST VII Preface to the First Edition Our intention has been to provide a short introduction to the chemistry and mode of action of insecticidal phosphoric acid compounds, with particular ref erence to the relationship between structure and activity. The yearly produc tion of these pesticides is now approaching 100,000 tons and thus offers an im portant example of applied research. If, however, one examines the historical development of these compounds, it is apparent that this was preceded by a hundred years of pure chemistry of phosphorus.
Organophosphorus Pesticides
Author: Morifusa Etō
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 410
Book Description
Nomenclature. Phosphates. Phosphorothionates. Phosphorothilothionates. Phosphorothiolates. Derivates of phosphoramidic acid. Phosphonates. Hydrolysis. Chemical reactions. Biochemistry. Individual Pesticides.
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 410
Book Description
Nomenclature. Phosphates. Phosphorothionates. Phosphorothilothionates. Phosphorothiolates. Derivates of phosphoramidic acid. Phosphonates. Hydrolysis. Chemical reactions. Biochemistry. Individual Pesticides.
The Chemistry of Organophosphorus Pesticides
Author: Christa Fest
Publisher: Springer
ISBN: 9780387058580
Category : Insecticides
Languages : en
Pages : 339
Book Description
Publisher: Springer
ISBN: 9780387058580
Category : Insecticides
Languages : en
Pages : 339
Book Description
Organophosphorus Pesticides
Author: Morifusa Eto
Publisher: CRC Press
ISBN: 1351092200
Category : Science
Languages : en
Pages : 705
Book Description
In order to get a general concept of organophosphorus pesticides with such a variety in structure and biological activities, consideration of each aspect of chemistry, biochemistry, and the applied sciences is necessary. This book consists of these three main parts. After the presentation of the background of phosphorus chemistry in Chapter 1, stress was put on the chemical and biochemical reactions of organophosphorus pesticides, including synthesis, analysis, metabolism mode of action, and other interesting aspects in Chapter 2 to 4, and on the structure-pesticidal activity relationship in Chapter 5.
Publisher: CRC Press
ISBN: 1351092200
Category : Science
Languages : en
Pages : 705
Book Description
In order to get a general concept of organophosphorus pesticides with such a variety in structure and biological activities, consideration of each aspect of chemistry, biochemistry, and the applied sciences is necessary. This book consists of these three main parts. After the presentation of the background of phosphorus chemistry in Chapter 1, stress was put on the chemical and biochemical reactions of organophosphorus pesticides, including synthesis, analysis, metabolism mode of action, and other interesting aspects in Chapter 2 to 4, and on the structure-pesticidal activity relationship in Chapter 5.
Organophosphates Chemistry, Fate, and Effects
Author: Janice E. Chambers
Publisher: Elsevier
ISBN: 0080917267
Category : Medical
Languages : en
Pages : 440
Book Description
This volume pulls together a wealth of up-to-date information on the toxicology of this diverse and ubiquitous class of insecticides. Leading experts review the reactivity of organophosphorus compounds with cholinesterase, as well as their metabolism and biological effects on humans and other nontarget organisms. The book not only covers the anticholinesterase actions of organophosphates, but also other, presumably independent, effects, such as teratogenicity, delayed neuropathy, immunotoxicity, and behavioral toxicity. Offers crucial overviews of chemical and biochemical reactivity and biological responsiveness of mainly nontarget organisms Reviews new developments in assessment of metabolism and disposition of organophosphorus compounds Examines organophosphorus compound-induced toxicity mediated by mechanisms other than inhibition of acetylcholinesterase Covers new research on differences in toxicity induced by the variety of organophosphorus Analyzes current controversies on the relevance of certain biochemical parameters in actual organophosphate toxicity in vivo
Publisher: Elsevier
ISBN: 0080917267
Category : Medical
Languages : en
Pages : 440
Book Description
This volume pulls together a wealth of up-to-date information on the toxicology of this diverse and ubiquitous class of insecticides. Leading experts review the reactivity of organophosphorus compounds with cholinesterase, as well as their metabolism and biological effects on humans and other nontarget organisms. The book not only covers the anticholinesterase actions of organophosphates, but also other, presumably independent, effects, such as teratogenicity, delayed neuropathy, immunotoxicity, and behavioral toxicity. Offers crucial overviews of chemical and biochemical reactivity and biological responsiveness of mainly nontarget organisms Reviews new developments in assessment of metabolism and disposition of organophosphorus compounds Examines organophosphorus compound-induced toxicity mediated by mechanisms other than inhibition of acetylcholinesterase Covers new research on differences in toxicity induced by the variety of organophosphorus Analyzes current controversies on the relevance of certain biochemical parameters in actual organophosphate toxicity in vivo
The Chemistry of Organophosphorus Compounds
Author: Deacon Palmer
Publisher: States Academic Press
ISBN: 9781639897377
Category : Science
Languages : en
Pages : 0
Book Description
Organophosphorus compounds are derivatives of phosphoric, phosphinic or phosphonic acid in which the oxygen atoms directly bind with the phosphorus atom and can be replaced by the atoms of nitrogen or sulfur. They are primarily used as pesticides and insecticides, and serve as a substitute to chlorinated hydrocarbons persisting in the environment. Despite their extensive uses, certain organophosphorus compounds are toxic for human beings. These compounds are abundant in nature and due to their inherent chemical properties, play a vital role in various sectors. Asymmetry, multivalency, variable oxidation states and metal-binding properties are a few of the notable characteristics that enhance their identification as a distinct and adaptable family of chemicals. There has been rapid progress in organophosphorus chemistry and its applications are finding their way across multiple industries. This book aims to shed light on some of the unexplored aspects of organophosphorus chemistry and the recent researches in this field. It also aims to equip students and experts with the advanced topics and upcoming concepts in this area of chemistry.
Publisher: States Academic Press
ISBN: 9781639897377
Category : Science
Languages : en
Pages : 0
Book Description
Organophosphorus compounds are derivatives of phosphoric, phosphinic or phosphonic acid in which the oxygen atoms directly bind with the phosphorus atom and can be replaced by the atoms of nitrogen or sulfur. They are primarily used as pesticides and insecticides, and serve as a substitute to chlorinated hydrocarbons persisting in the environment. Despite their extensive uses, certain organophosphorus compounds are toxic for human beings. These compounds are abundant in nature and due to their inherent chemical properties, play a vital role in various sectors. Asymmetry, multivalency, variable oxidation states and metal-binding properties are a few of the notable characteristics that enhance their identification as a distinct and adaptable family of chemicals. There has been rapid progress in organophosphorus chemistry and its applications are finding their way across multiple industries. This book aims to shed light on some of the unexplored aspects of organophosphorus chemistry and the recent researches in this field. It also aims to equip students and experts with the advanced topics and upcoming concepts in this area of chemistry.
Best Synthetic Methods
Author: Chris Timperley
Publisher: Newnes
ISBN: 0080982247
Category : Science
Languages : en
Pages : 786
Book Description
Best Synthetic Methods: Organophosphorus (V) Chemistry provides systematic coverage of the most common classes of pentavalent organophosphorus compounds and reagents (including phosphonyl, phosphoryl, and organophosphates), and allows researchers an easy point of entry into this complex and economically important field. The book follows the Best Synthetic Methods format, containing practical methods, synthetic tips, and shortcuts. Where relevant, articles include toxicity data and historical context for the reactions. Typical analytical and spectroscopic data are also presented to enable scientists to identify key compound characteristics. The book is a valuable companion to research chemists in both academia and industry, summarizing the best practical methods (often originating in difficult-to-access, foreign-language primary literature) in one place. It is ideally suited for those working on industrial applications of these compounds, including insecticides, herbicides, flame retardants, and plasticizers. Includes a mixture of tried and tested, historical methods that are proven to work, alongside new methods to provide scientists with a quick, time-saving resource of reliable methods Includes tips and tricks to get reactions to work; important information often missing from other sources Includes key analytical data for compounds, so scientists have one handy resource to select, perform, and analyze the best reaction
Publisher: Newnes
ISBN: 0080982247
Category : Science
Languages : en
Pages : 786
Book Description
Best Synthetic Methods: Organophosphorus (V) Chemistry provides systematic coverage of the most common classes of pentavalent organophosphorus compounds and reagents (including phosphonyl, phosphoryl, and organophosphates), and allows researchers an easy point of entry into this complex and economically important field. The book follows the Best Synthetic Methods format, containing practical methods, synthetic tips, and shortcuts. Where relevant, articles include toxicity data and historical context for the reactions. Typical analytical and spectroscopic data are also presented to enable scientists to identify key compound characteristics. The book is a valuable companion to research chemists in both academia and industry, summarizing the best practical methods (often originating in difficult-to-access, foreign-language primary literature) in one place. It is ideally suited for those working on industrial applications of these compounds, including insecticides, herbicides, flame retardants, and plasticizers. Includes a mixture of tried and tested, historical methods that are proven to work, alongside new methods to provide scientists with a quick, time-saving resource of reliable methods Includes tips and tricks to get reactions to work; important information often missing from other sources Includes key analytical data for compounds, so scientists have one handy resource to select, perform, and analyze the best reaction
Chemistry and Fate of Organophosphorus Compounds
Author: E. Merian
Publisher: Taylor & Francis
ISBN: 9782881242151
Category : Science
Languages : en
Pages : 232
Book Description
First published in 1987. Routledge is an imprint of Taylor & Francis, an informa company.
Publisher: Taylor & Francis
ISBN: 9782881242151
Category : Science
Languages : en
Pages : 232
Book Description
First published in 1987. Routledge is an imprint of Taylor & Francis, an informa company.
The Chemistry of Pesticides
Author: Kenneth Arnold Hassall
Publisher:
ISBN:
Category : Technology & Engineering
Languages : en
Pages : 396
Book Description
Naslagwerk voor studenten en wetenschappers
Publisher:
ISBN:
Category : Technology & Engineering
Languages : en
Pages : 396
Book Description
Naslagwerk voor studenten en wetenschappers
Toxicology of Organophosphate and Carbamate Compounds
Author: Ramesh C. Gupta
Publisher: Academic Press
ISBN: 9780080543109
Category : Science
Languages : en
Pages : 768
Book Description
This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. Describes everything you need to know about Organophosphates and Carbamates Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity Describes recent advancements in cholinesterases, paraoxonases, carboxylesterases, oxidative stress, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis Provides in vitro and in vivo models for neurotoxicity testing Integrates knowledge of studies in lab animals and humans Offers risk/safety assessment and national/international guidelines for permissible levels of pesticide residues Describes management of Anticholinesterase poisoning in humans
Publisher: Academic Press
ISBN: 9780080543109
Category : Science
Languages : en
Pages : 768
Book Description
This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. Describes everything you need to know about Organophosphates and Carbamates Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity Describes recent advancements in cholinesterases, paraoxonases, carboxylesterases, oxidative stress, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis Provides in vitro and in vivo models for neurotoxicity testing Integrates knowledge of studies in lab animals and humans Offers risk/safety assessment and national/international guidelines for permissible levels of pesticide residues Describes management of Anticholinesterase poisoning in humans