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The Neurobiological Basis of Suicide

The Neurobiological Basis of Suicide PDF Author: Yogesh Dwivedi
Publisher: CRC Press
ISBN: 143983881X
Category : Medical
Languages : en
Pages : 485

Book Description
With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

The Neurobiological Basis of Suicide

The Neurobiological Basis of Suicide PDF Author: Yogesh Dwivedi
Publisher: CRC Press
ISBN: 143983881X
Category : Medical
Languages : en
Pages : 485

Book Description
With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

The Neurobiological Basis of Suicide

The Neurobiological Basis of Suicide PDF Author: Yogesh Dwivedi
Publisher: CRC Press
ISBN: 1439838828
Category : Medical
Languages : en
Pages : 482

Book Description
With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment

Oxford Textbook of Suicidology and Suicide Prevention

Oxford Textbook of Suicidology and Suicide Prevention PDF Author: Danuta Wasserman
Publisher: Oxford University Press, USA
ISBN: 0198834446
Category : Medical
Languages : en
Pages : 857

Book Description
Part of the authoritative Oxford Textbooks in Psychiatry series, the new edition of the Oxford Textbook of Suicidology and Suicide Prevention remains a key text in the field of suicidology, fully updated with new chapters devoted to major psychiatric disorders and their relation to suicide.

Neurobiology of Bipolar Disorder

Neurobiology of Bipolar Disorder PDF Author: Joao Quevedo
Publisher: Academic Press
ISBN: 012819183X
Category : Medical
Languages : en
Pages : 472

Book Description
The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder

Neurobiology of Depression

Neurobiology of Depression PDF Author: Joao Luciano de Quevedo
Publisher: Academic Press
ISBN: 0128133341
Category : Medical
Languages : en
Pages : 471

Book Description
Neurobiology of Depression: Road to Novel Therapeutics synthesizes the basic neurobiology of major depressive disorder with discussions on the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing research perspectives and revolutionizing research into depression. These basic foundational understandings on the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research are combined in this book to aid advanced students and researchers in their understanding of MDD. Depression is one of the most common mental-health disorders caused by a variety of genetic, biological, environmental and psychological factors. Major depressive disorder (MDD) is typically treated with first-line antidepressant agents that primarily target monoamine neurotransmission. However, only approximately one-third of patients with MDD achieve remission following a trial with such an antidepressant. Furthermore, MDD is a heterogeneous phenotype, and new frameworks, such as the NIMH Research Domain Criteria (RDoC) may provide a more accurate, biologically based comprehension of the symptomatic heterogeneity of this devastating illness. Aids readers in understanding major depressive disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments, to antidepressants and novel therapeutics Synthesizes discussions on the cellular and molecular mechanisms underlying symptoms with the clinical aspects of depression

Handbook of Youth Suicide Prevention

Handbook of Youth Suicide Prevention PDF Author: Regina Miranda
Publisher: Springer Nature
ISBN: 3030824659
Category : Psychology
Languages : en
Pages : 448

Book Description
This handbook examines research on youth suicide, analyzes recent data on suicide among adolescents, and addresses the subject matter as a serious public health concern. The book explores the research on youth suicide, examining its causes, new and innovative ways of determining suicide risk, and evidence-based intervention and prevention strategies. In addition, it focuses on specific under-studied populations, including adolescents belonging to ethnic, racial, and sexual minority groups, youth involved in the criminal justice system, and adolescents in foster care. The book discusses how culturally informed and targeted interventions can help to decrease suicide risk for these populations. Key areas of coverage include: Early childhood adversity, stress, and developmental pathways of suicide risk. The neurobiology of youth suicide. Suicide, self-harm, and the media. Assessment of youth suicidal behavior with explicit and implicit measures. Suicide-related risk among immigrant, ethnic, and racial minority youth. LGBTQ youth and suicide prevention. Psychosocial treatments for ethnoculturally diverse youth with suicidal thoughts and behaviors. Technology-enhanced interventions and youth suicide prevention. The Handbook of Youth Suicide Prevention is an essential resource for researchers, professors, graduate students as well as clinicians, therapists, and other professionals in developmental psychology, social work, public health, pediatrics, family studies, child and adolescent psychiatry, school and educational psychology, and all interrelated disciplines. Chapters 8, 9 and 16 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Neurobiology of Brain Disorders

Neurobiology of Brain Disorders PDF Author: Michael J. Zigmond
Publisher: Elsevier
ISBN: 0123982804
Category : Science
Languages : en
Pages : 824

Book Description
Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases. Links basic, translational, and clinical research on disorders of the nervous system, creating a format for study that will accelerate disease prevention and treatment Covers a vast array of neurological disorders, including ADHD, Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson, Huntington, Alzheimer, OCD, PTSD, schizophrenia, depression, and pain Illustrated in full color Each chapter provides in-text summary points, special feature boxes, and research questions Provides an up-to-date synthesis of primary source material

Neurobiology of Post-traumatic Stress Disorder

Neurobiology of Post-traumatic Stress Disorder PDF Author: Leo Sher
Publisher: Nova Science Publishers
ISBN: 9781614705932
Category : Neurobiology
Languages : en
Pages : 0

Book Description
Post-Traumatic Stress Disorder (PTSD) is a common and severe psychiatric disorder precipitated by exposure to a psychologically distressing event. PTSD is associated with significant morbidity and mortality and is characterised by the presence of three distinct, but co-occurring, symptom clusters. Research evidence suggests that PTSD has a neurobiological basis. Current research on the neurobiology of PTSD include the utilisation of functional brain imaging; molecular genetic research; and, the incorporation of cross-system research including neuroendocrine, neurochemical, and neuroimmunological systems. This book examines the neurobiological basis of PTSD and the future research goals in regards to these findings.

The Oxford Handbook of Suicide and Self-Injury

The Oxford Handbook of Suicide and Self-Injury PDF Author: Matthew K. Nock
Publisher: Oxford University Press
ISBN: 0190209143
Category : Psychology
Languages : en
Pages : 544

Book Description
Suicide is a perplexing human behavior that remains among the leading causes of death worldwide, responsible for more deaths each year than all wars, genocide, and homicide combined. Although suicide and other forms of self-injury have baffled scholars and clinicians for thousands of years, the past few decades have brought significant leaps in our understanding of these behaviors. This volume provides a comprehensive summary of the most important and exciting advances in our understanding of suicide and self-injury and our ability to predict and prevent it. Comprised of a formidable who's who in the field, the handbook covers the full spectrum of topics in suicide and self-injury across the lifespan, including the classification of different self-injurious behaviors, epidemiology, assessment techniques, and intervention. Chapters probe relevant issues in our society surrounding suicide, including assisted suicide and euthanasia, suicide terrorism, overlap between suicidal behavior and interpersonal violence, ethical considerations for suicide researchers, and current knowledge on survivors of suicide. The most comprehensive handbook on suicide and self-injury to date, this volume is a must-read text for graduate students, fellows, academic and research psychologists, and other researchers working in the brain and behavioral sciences.

Reducing Suicide

Reducing Suicide PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309169437
Category : Medical
Languages : en
Pages : 512

Book Description
Every year, about 30,000 people die by suicide in the U.S., and some 650,000 receive emergency treatment after a suicide attempt. Often, those most at risk are the least able to access professional help. Reducing Suicide provides a blueprint for addressing this tragic and costly problem: how we can build an appropriate infrastructure, conduct needed research, and improve our ability to recognize suicide risk and effectively intervene. Rich in data, the book also strikes an intensely personal chord, featuring compelling quotes about people's experience with suicide. The book explores the factors that raise a person's risk of suicide: psychological and biological factors including substance abuse, the link between childhood trauma and later suicide, and the impact of family life, economic status, religion, and other social and cultural conditions. The authors review the effectiveness of existing interventions, including mental health practitioners' ability to assess suicide risk among patients. They present lessons learned from the Air Force suicide prevention program and other prevention initiatives. And they identify barriers to effective research and treatment. This new volume will be of special interest to policy makers, administrators, researchers, practitioners, and journalists working in the field of mental health.