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The Placebo Effect in Clinical Practice

The Placebo Effect in Clinical Practice PDF Author: Walter A. Brown
Publisher: Oxford University Press
ISBN: 0199933855
Category : Health & Fitness
Languages : en
Pages : 188

Book Description
The Placebo Effect in Clinical Practice brings together what we know about the mechanisms behind the placebo response, as well as the procedures that promote these responses, in order to provide a focused and concise overview on how current knowledge can be applied in treatment settings.

The Placebo Effect in Clinical Practice

The Placebo Effect in Clinical Practice PDF Author: Walter A. Brown
Publisher: Oxford University Press
ISBN: 0199933855
Category : Health & Fitness
Languages : en
Pages : 188

Book Description
The Placebo Effect in Clinical Practice brings together what we know about the mechanisms behind the placebo response, as well as the procedures that promote these responses, in order to provide a focused and concise overview on how current knowledge can be applied in treatment settings.

Talking Cures and Placebo Effects

Talking Cures and Placebo Effects PDF Author: David A. Jopling
Publisher: Oxford University Press, USA
ISBN: 0199239509
Category : Medical
Languages : en
Pages : 333

Book Description
Psychodynamic psychotherapy and psychoanalysis have had to defend themselves from a barrage of criticisms throughout their history. In this book David Jopling argues that the changes achieved through therapy are really just functions of placebos that rally the mind's native healing powers. It is a bold new work that delivers yet another blow to Freud and his followers.

Science of the Placebo

Science of the Placebo PDF Author: Harry Guess
Publisher: BMJ Books
ISBN: 9780727915948
Category : Medical
Languages : en
Pages : 346

Book Description
Based on a meeting in November 2000, this book brings together researchers from a wide range of disciplines to examine the biological, behavioral, social, cultural and ethical aspects related to the placebo effect. Perspectives on the necessity for including a placebo in randomized clinical trials will also be examined. This is the first attempt to examine the evidence-base of the placebo effect and will provide important information for clinicans.

Placebo Effects: The Meaning of Care in Medicine

Placebo Effects: The Meaning of Care in Medicine PDF Author: Pekka Louhiala
Publisher: Springer
ISBN: 9783030273279
Category : Philosophy
Languages : en
Pages : 134

Book Description
This book provides a perspective on the concepts placebo and placebo effects, which has been missing so far: a detailed analysis of the history of the terms, their current use, suggested alternatives and the implications of the conceptual confusion. Everybody knows something about placebos and placebo effects. If, however, people are asked to define the concepts, the spectrum becomes wide. Does 'placebo' refer to an inert treatment or does it cover all elements of the patient-physician-interaction except for pharmacological or other physiological mechanisms? Furthermore, if, by definition, a placebo has no effect, what sense does it make to talk about a 'placebo effect'? Even in scientific literature the concepts ‘placebo’ and ‘placebo effect’ are used in many senses and often in a confusing way. While this book discusses many issues which keep puzzling physicians, it also covers the historical developments of the concepts of placebo and placebo effect as well as the conceptual confusion in the definitions. This book is intended for physicians, philosophers, psychologists and any other people interested in placebos, placebo effects and the physician-patient relationship.

Understanding the Placebo Effect in Complementary Medicine

Understanding the Placebo Effect in Complementary Medicine PDF Author: David Peters
Publisher:
ISBN: 9780443060311
Category : Medical
Languages : en
Pages : 235

Book Description
As the placebo effect continues to elicit passionate debate, this book tackles issues of the placebo effect in complementary medicine, and is targeted to both the experienced practitioner and the new student.

Placebo Effects

Placebo Effects PDF Author: Fabrizio Benedetti
Publisher:
ISBN: 9780191724022
Category : Placebo (Medicine)
Languages : en
Pages : 295

Book Description
This is the first book to critically review the mechanisms of placebo effects across all medical conditions, diseases and therapies. It is the definitive text on the placebo effect, and will be essential for researchers and clinicians in all medical specialties.

Oxford Textbook of Osteoarthritis and Crystal Arthropathy, Third Edition

Oxford Textbook of Osteoarthritis and Crystal Arthropathy, Third Edition PDF Author: Michael Doherty
Publisher: Oxford University Press
ISBN: 0199668841
Category : Medical
Languages : en
Pages : 529

Book Description
A trustworthy clinical companion, the textbook offers best practice and management strategies for these common joint diseases. Formerly published as Osteoarthritis, the extensively revised third edition of the Oxford Textbook of Osteoarthritis and Crystal Arthropathy provides up-to-date and evidence-based guidance on how to assess, diagnose, and manage patients. A prestigious and international author team ensure information is expert and relevant-this is a practical tool for clinicians managing people with osteoarthritis, gout, and other crystal-associated arthritis. Confidently consider and chose the right blend of treatment for your patient, whether physical, pharmacological, surgical, or supportive. The Oxford Textbook of Osteoarthritis and Crystal Arthropathy provides full coverage of joint failure, and includes detailed sections on epidemiology, risk factors, clinical assessment, and investigations. This edition also now includes new sections on gout and other crystal arthropathies. Clinically relevant and easily understandable overviews of basic science, including pathology and pain physiology, along with critical appraisal of current guidelines, make this a highly valuable resource. Significant coverage is also given to patient education and the involvement of the patient in management planning. Also highly illustrated, the textbook is a strong reference tool with summary boxes and key points at the end of chapters making it easy to find information quickly and help you deliver the optimum patient outcome. The textbook equips rheumatologists and musculoskeletal health professionals with the knowledge to provide best possible patient care.

Small Clinical Trials

Small Clinical Trials PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309171148
Category : Medical
Languages : en
Pages : 221

Book Description
Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.

The Placebo Effect

The Placebo Effect PDF Author: Anne Harrington
Publisher: Harvard University Press
ISBN: 9780674669864
Category : Chemotherapy
Languages : en
Pages : 276

Book Description
Beginning with a review of the role of placebos in the history of medicine, this book investigates the current surge of interest in placebos, and probes the methodological difficulties of saying scientifically just what placebos can and cannot do.

The Prevention and Treatment of Missing Data in Clinical Trials

The Prevention and Treatment of Missing Data in Clinical Trials PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 030918651X
Category : Medical
Languages : en
Pages : 163

Book Description
Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data.