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Theoretical and Mathematical Foundations of Human Health Risk Analysis

Theoretical and Mathematical Foundations of Human Health Risk Analysis PDF Author: Douglas J. Crawford-Brown
Publisher: Springer Science & Business Media
ISBN: 1461561434
Category : Technology & Engineering
Languages : en
Pages : 208

Book Description
Scientists and regulators have struggled to define the role of theory, experiments, models and common sense in risk analysis. This situation has been made worse by the isolation of theory from modeling, of experimentation from theory, and of practical action from basic science. This book arises from efforts at regulatory agencies and industries to bring more science into health risk analysis so that society may better use limited resources to improve public health. This book covers: the characterization of exposure to pollutants and other sources of risk; the movement of pollutants into the body via inhalation; ingestion, dermal absorption, and exposures to radiation; the movement of a pollutant as it cascades through the tissues and organs of the body; and the development of principles and models for dose-response modeling. The book shows how an understanding of the biological, chemical, and physical properties of the environment and of the human body can guide the selection of mathematical models, and how these models can aid in estimating risks. Included in the book are models covering the full range of topics in human health risk analysis: exposure assessment, rates of intake, deposition and uptake by organs, absorption across membranes, biokinetics, dosimetry, and dose-response. The reader will gain from the book a better understanding of how environmental health science, as applied in risk analysis, can be used to create a more rational basis for the improvement of public health.

Theoretical and Mathematical Foundations of Human Health Risk Analysis

Theoretical and Mathematical Foundations of Human Health Risk Analysis PDF Author: Douglas J. Crawford-Brown
Publisher: Springer Science & Business Media
ISBN: 1461561434
Category : Technology & Engineering
Languages : en
Pages : 208

Book Description
Scientists and regulators have struggled to define the role of theory, experiments, models and common sense in risk analysis. This situation has been made worse by the isolation of theory from modeling, of experimentation from theory, and of practical action from basic science. This book arises from efforts at regulatory agencies and industries to bring more science into health risk analysis so that society may better use limited resources to improve public health. This book covers: the characterization of exposure to pollutants and other sources of risk; the movement of pollutants into the body via inhalation; ingestion, dermal absorption, and exposures to radiation; the movement of a pollutant as it cascades through the tissues and organs of the body; and the development of principles and models for dose-response modeling. The book shows how an understanding of the biological, chemical, and physical properties of the environment and of the human body can guide the selection of mathematical models, and how these models can aid in estimating risks. Included in the book are models covering the full range of topics in human health risk analysis: exposure assessment, rates of intake, deposition and uptake by organs, absorption across membranes, biokinetics, dosimetry, and dose-response. The reader will gain from the book a better understanding of how environmental health science, as applied in risk analysis, can be used to create a more rational basis for the improvement of public health.

Information Resources in Toxicology

Information Resources in Toxicology PDF Author: P.J. Bert Hakkinen
Publisher: Elsevier
ISBN: 008053466X
Category : Medical
Languages : en
Pages : 921

Book Description
Information Resources in Toxicology, Third Edition is a sourcebook for anyone who needs to know where to find toxicology information. It provides an up-to-date selective guide to a large variety of sources--books, journals, organizations, audiovisuals, internet and electronic sources, and more. For the Third Edition, the editors have selected, organized, and updated the most relevant information available. New information on grants and other funding opportunities, physical hazards, patent literature, and technical reports have also been added. This comprehensive, time-saving tool is ideal for toxicologists, pharmacologists, drug companies, testing labs, libraries, poison control centers, physicians, legal and regulatory professionals, and chemists. Serves as an all-in-one resource for toxicology information New edition includes information on publishers, grants and other funding opportunities, physical hazards, patent literature, and technical reports Updated to include the latest internet and electronic sources, e-mail addresses, etc. Provides valuable data about the new fields that have emerged within toxicological research; namely, the biochemical, cellular, molecular, and genetic aspects

Interdisciplinary Perspectives on Drinking Water Risk Assessment and Management

Interdisciplinary Perspectives on Drinking Water Risk Assessment and Management PDF Author: Eric G. Reichard
Publisher:
ISBN: 9781901502114
Category : Drinking water
Languages : en
Pages : 196

Book Description


Handbook of Environmentally Conscious Manufacturing

Handbook of Environmentally Conscious Manufacturing PDF Author: Christian N. Madu
Publisher: Springer Nature
ISBN: 3030758346
Category : Business & Economics
Languages : en
Pages : 264

Book Description
Manufacturers, under pressure from their major stakeholders, integrate environmental issues in the design and management of their products. These stakeholders include customers, regulators, employees, communities, and interest groups who have a common stake in protecting the earth from pollution and in limiting the exploitation of earth's limited natural resources. Manufacturers recognize that being environmentally responsible also offers competitive advantage to the firm. The Handbook of Environmentally Conscious Manufacturing is written as a state-of-the-art reference to guide environmentally conscious manufacturing (ECM). All the contributors have done extensive research and/or practice work in the field of ECM. The Handbook covers all the major topics in Environmentally Conscious Manufacturing. There are specific chapters to deal with sustainable manufacturing, recycling, eco-labelling, life cycle assessment, and ISO 14000 series of standards, as well as decision-making aspects of Environmentally Conscious Manufacturing. Decision-oriented topics on supply chain, decision models, quality initiative, environmental costing and decision support systems are also covered. The influence of ECM on marketing imperative is also covered.

Green Manufacturing

Green Manufacturing PDF Author: David A. Dornfeld
Publisher: Springer Science & Business Media
ISBN: 1441960163
Category : Technology & Engineering
Languages : en
Pages : 291

Book Description
Green Manufacturing: Fundamentals and Applications introduces the basic definitions and issues surrounding green manufacturing at the process,machine and system (including supply chain) levels. It also shows, by way of several examples from different industry sectors, the potential for substantial improvement and the paths to achieve the improvement. Additionally, this book discusses regulatory and government motivations for green manufacturing and outlines the path for making manufacturing more green as well as making production more sustainable. This book also: Discusses new engineering approaches for manufacturing and provides a path from traditional manufacturing to green manufacturing Addresses regulatory and economic issues surrounding green manufacturing Details new supply chains that need to be in place before going green Includes state-of-the-art case studies in the areas of automotive, semiconductor and medical areas as well as in the supply chain and packaging areas

Risk-Based Environmental Decisions

Risk-Based Environmental Decisions PDF Author: Douglas J. Crawford-Brown
Publisher: Springer Science & Business Media
ISBN: 1461552273
Category : Technology & Engineering
Languages : en
Pages : 228

Book Description
Risk-Based Environmental Decision: Methods and Culture presents the principles of human health risk analysis as they are applied in environmental decisions. It balances the discussion of scientific theory and methods, philosophical analysis, and applications in regulatory decisions. The material is directed towards risk analysts who must apply their skills in a policy setting, and towards policy analysts who must use risk estimates. The presentation is suited ideally as an introductory text on the methods of risk analysis and on the cultural issues that underlie these methodologies. An important feature of Risk-Based Environmental Decision: Methods and Culture is that it is designed around a series of detailed case studies of environmental risk analysis which walk the reader from the historical nature of the problem, to the formulation as a risk-based problem, to the conduct of risk analysis, and on to the application, debate, and defense of the risk analysis.

Risk Analysis Foundations, Models, and Methods

Risk Analysis Foundations, Models, and Methods PDF Author: Louis Anthony Cox Jr.
Publisher: Springer Science & Business Media
ISBN: 1461508479
Category : Business & Economics
Languages : en
Pages : 564

Book Description
Risk Analysis: Foundations, Models, and Methods fully addresses the questions of "What is health risk analysis?" and "How can its potentialities be developed to be most valuable to public health decision-makers and other health risk managers?" Risk analysis provides methods and principles for answering these questions. It is divided into methods for assessing, communicating, and managing health risks. Risk assessment quantitatively estimates the health risks to individuals and to groups from hazardous exposures and from the decisions or activities that create them. It applies specialized models and methods to quantify likely exposures and their resulting health risks. Its goal is to produce information to improve decisions. It does this by relating alternative decisions to their probable consequences and by identifying those decisions that make preferred outcomes more likely. Health risk assessment draws on explicit engineering, biomathematical, and statistical consequence models to describe or simulate the causal relations between actions and their probable effects on health. Risk communication characterizes and presents information about health risks and uncertainties to decision-makers and stakeholders. Risk management applies principles for choosing among alternative decision alternatives or actions that affect exposure, health risks, or their consequences.

Mathematical Methods of Environmental Risk Modeling

Mathematical Methods of Environmental Risk Modeling PDF Author: Douglas J. Crawford-Brown
Publisher: Springer Science & Business Media
ISBN: 1475732716
Category : Technology & Engineering
Languages : en
Pages : 212

Book Description
Mathematical Methods of Environmental Risk Modeling provides a working introduction to both the general mathematical methods and specific models used for human health risk assessment. Rather than being purely an applied math book, this book focuses on methods and models that students and professionals are likely to encounter in practice. Examples are given from exposure assessment, pharmacokinetic modeling, and dose-response modeling.

Quantifying Public Health Risk Reduction Benefits

Quantifying Public Health Risk Reduction Benefits PDF Author: Robert S. Raucher
Publisher: American Water Works Association
ISBN: 1583211926
Category : Cost effectiveness
Languages : en
Pages : 386

Book Description
To assist the implementation of benefit-cost analysis, this research report describes issues and techniques related to estimating the human health risk reduction benefits provided by actions that reduce contaminant concentrations in drinking water, and discusses how these benefits should be compared to costs. Material is relevant for evaluating the benefits and costs of federal and state regulatory actions such as setting a Maximum Contaminant Level, instituting treatment requirements, and implementing a guideline or advisory. The report will be of interest to water utility professionals, benefit- cost practitioners, and public policy decision makers. No subject index. Annotation copyrighted by Book News Inc., Portland, OR.

Spatiotemporal Environmental Health Modelling: A Tractatus Stochasticus

Spatiotemporal Environmental Health Modelling: A Tractatus Stochasticus PDF Author: George Christakos
Publisher: Springer Science & Business Media
ISBN: 1475728115
Category : Medical
Languages : en
Pages : 411

Book Description
Spatiotemporal Environmental Health Modelling: A Tractatus Stochasticus provides a holistic, conceptual and quantitative framework for Environmental Health Modelling in space-time. The holistic framework integrates two aspects of Environmental Health Science that have been previously treated separately: the environmental aspect, which involves the natural processes that bring about human exposure to harmful substances; and the health aspect, which focuses on the interactions of these substances with the human body. Some of the fundamental issues addressed in this work include variability, scale, uncertainty, and space-time connectivity. These topics are important in the characterization of natural systems and health processes. Spatiotemporal Environmental Health Modelling: A Tractatus Stochasticus explains why modern stochastics is the appropriate mechanical vehicle for addressing such issues in a rigorous way. In particular, modern stochastics incorporates concepts and methods from probability, classical statistics, geostatistics, statistical mechanics and field theory. The authors present a synthetic view of environmental health that embraces all of the various components and focuses on their mutual interactions. Spatiotemporal Environmental Health Modeling: A Tractatus Stochasticus includes new material on Bayesian maximum entropy estimation techniques and space-time random field estimation methods. The authors show why these methods have clear advantages over the classical geostatistical estimation procedures and how they can be used to provide accurate space-time maps of environmental health processes. Also included are expositions of diagrammatic perturbation and renormalization group analysis, which have not been previously discussed within the context of Environmental Health. Finally, the authors present stochastic indicators that can be used for large-scale characterization of contamination and investigations of health effects at the microscopic level. This book will be a useful reference to both researchers and practitioners of Environmental Health Sciences. It will appeal specifically to environmental engineers, geographers, geostatisticians, earth scientists, toxicologists, epidemiologists, pharmacologists, applied mathematicians, physicists and biologists.