Fluorescent Light-emitting Diode (LED) Microscopy for Diagnosis of Tuberculosis PDF Download

Author: World Health Organization
Publisher:
ISBN: 9789241501613
Category : Fluorescence microscopy
Languages : en
Pages : 12

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Book Description
Light-emitting diodes (LED) have been developed to offer the benefits of fluorescence microscopy without the associated costs. In 2009, the evidence for the efficacy of LED microscopy was assessed by the World Health Organization, on the basis of standards appropriate for evaluating both the accuracy and the effect of new TB diagnostics on patients and public health. The results showed that the accuracy of LED microscopy was equivalent to that of international reference standards, it was more sensitive than conventional Ziehl-Neelsen microscopy and it had qualitative, operational and cost advantages over both conventional fluorescence and Ziehl-Neelsen microscopy. On the basis of these findings, WHO recommends that conventional fluorescence microscopy be replaced by LED microscopy, and that LED microscopy be phased in as an alternative for conventional Ziehl-Neelsen light microscopy.

Author: Jean-Marie Kayembe
Publisher: BoD – Books on Demand
ISBN: 1789237815
Category : Medical
Languages : en
Pages : 202

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Book Description
Tuberculosis is an ancient disease with a high incidence and mortality rate, unequally distributed worldwide. Epidemiological indicators, but also risk factors, play a key role in the natural history of the disease and need to be regulary addressed. Low and middle income countries are not prepared for appropriate response and are also the most affected. The incidence of this extrapulmonary disease is far from being clearly established. Epidemiological studies in different geographical areas will help in this field.

Author: Amit Singh
Publisher: Springer Nature
ISBN: 9819956242
Category : Science
Languages : en
Pages : 274

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Book Description
This book covers all the aspects related to the laboratory diagnosis of Mycobacterium. Laboratory diagnosis includes microscopic to advance molecular diagnosis. Moreover, it deals with the methods used to detect antimycobacterial susceptibility tests and drug resistance. Chapters cover most potential methods and techniques from traditional to advanced future diagnostics for identifying tuberculosis, NTM, and latent TB infections. Also discussed the challenges and opportunities in the diagnostic science of infectious disease. This book offers assistance to students, postgraduate medical students, researchers, medical practitioners, postdoctoral fellows, microbiologists, nurses, and public health officers working in tuberculosis control programs to understand various modalities for diagnosis and drug-resistance tuberculosis.

Author: World Health Organization
Publisher:
ISBN: 9789241506700
Category : Medical
Languages : en
Pages : 0

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Book Description
In December 2010, WHO first recommended the use of the Xpert MTB/RIF assay. The WHO's policy statement was supported by a rapid implementation document, which provided the technical "how-to" and operational considerations for rolling out the use of the assay. An unprecedented uptake of this new technology followed the release of WHO's policy: by the end of March 2014, more than 2,300 GeneXpert instruments and more than 6 million Xpert MTB/RIF cartridges had been procured in the public sector in 104 countries eligible for concessional prices. An Expert Group was convened by WHO in May 2013 to review the current body of evidence on use of Xpert MTB/RIF. The resulting recommendations from the Expert Group are included in the WHO Policy update, which widens the recommended use of Xpert MTB/RIF, including for the diagnosis of paediatric TB and on selected specimens for the diagnosis of extrapulmonary TB, and includes an additional recommendation on the use of Xpert MTB/RIF as the initial diagnostic test in all individuals presumed to have pulmonary TB. The accompanying Xpert MTB/RIF implementation manual has been developed to replace the first edition and takes into consideration the current body of evidence and operational experiences available, in the context of the Policy update.

Author: Irini Sereti
Publisher: Springer Nature
ISBN: 3030291081
Category : Medical
Languages : en
Pages : 348

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Book Description
Globally, HIV-associated tuberculosis is one of the most important causes of infection-related death, accounting for one in every three HIV deaths and over 300,000 in 2017 alone. The HIV epidemic has undermined tuberculosis-control efforts in many countries around the world, as the virus has important modifying effects on the pathogenesis, diagnosis, and treatment of TB. The management of HIV-associated TB is also complicated by rapid clinical progression, immune reconstitution inflammatory syndrome, drug-drug interactions, and shared toxicities. The past two decades have yielded thousands of research publications and review articles on HIV-associated TB. HIV and Tuberculosis: A Formidable Alliance consolidates this massive amount of data into a single resource. With contributions from myriad disciplines, including epidemiology, immunology, public health, and clinical medicine, this book provides well-rounded and thorough coverage that will appeal to researchers and clinicians alike.

Author: Yi-Wei Tang
Publisher: Springer
ISBN: 3319951114
Category : Medical
Languages : en
Pages : 760

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Book Description
In recent years, advanced molecular techniques in diagnostic microbiology have been revolutionizing the practice of clinical microbiology in the hospital setting. Molecular diagnostic testing in general and nucleic acid-based amplification methods in particular have been heralded as diagnostic tools for the new millennium. This third edition covers not only the most recent updates and advances, but details newly invented omic techniques, such as next generation sequencing. It is divided into two distinct volumes, with Volume 1 describing the techniques, and Volume 2 addressing their applications in the field. In addition, both volumes focus more so on the clinical relevance of the test results generated by these techniques than previous editions.

Author: Digambar Behera
Publisher: JP Medical Ltd
ISBN: 9386322013
Category : Medical
Languages : en
Pages : 216

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Book Description
This book is a practical guide to the diagnosis and management of tuberculosis. Presented in a step by step approach, the text provides the latest information in the specialty, guiding clinicians through the history of the disease, its epidemiology, pathogenesis and pathology, to clinical presentation, imaging, diagnosis, and treatment options. The book is enhanced by illustrations and figures, and provides a clear understanding of the management of the disease from a global perspective and the challenges associated with tuberculosis care. Key points Practical guide to diagnosis and management of tuberculosis Presented in a step by step approach, providing latest information in the field Includes illustrations and figures to assist learning Provides clear understanding of challenges associated with tuberculosis care

Author: Giovanni Battista Migliori
Publisher: European Respiratory Society
ISBN: 1849841004
Category : Medical
Languages : en
Pages : 480

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Book Description
With over 10 million new TB cases and 1.6 million deaths, TB is a global health priority. Multidrug-resistant TB is of particular concern to both clinicians and national TB programmes: in 2017, there were 558 000 new rifampicin-resistant cases and 460 000 confirmed multidrug-resistant TB cases. Despite extensive investigation over the years, there is still a great deal to learn about the prevention, diagnosis and treatment of TB. This Monograph brings together chapters from global TB experts and begins with a patients’ perspective that sets the tone. The following chapters cover: the history of TB; epidemiology; strategies for control and elimination; clinical and laboratory diagnosis; imaging; treatment and drugs; TB in children and different patient populations; comorbidities; clinical cases; and much more.

Author: Jeffrey R. Starke
Publisher: Oxford University Press
ISBN: 0190695315
Category : Medical
Languages : en
Pages : 449

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Book Description
'The Handbook of Child and Adolescent Tuberculosis' is a state of the art clinical reference written and edited by the world's leading experts in childhood tuberculosis. It offers clinicians in any geography or setting practical, evidence-based advice on all aspects of the disease.

Author: T. F. Ashavaid
Publisher: Elsevier Health Sciences
ISBN: 1455744123
Category : Medical
Languages : en
Pages : 261

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Book Description
This issue of Clinics in Laboratory Medicine on the topic of Laboratory Medicine in India will be Guest Edited by Tester F. Ashavaid, PhD, FACB, CSCi, and include the following article topics: Tuberculosis; Malaria; STIs and Dengue; Visceral Leishmaniasis; Neglected Tropical Diseases; Hepatitis; HIV; Diabetes; Cardiovascular diseases; Stroke; HPV / Cervical screening; Multiple congenital anomalies; Down Syndrome/Thalessemia; Muscle dystrophy; Spinal muscular atrophy; Wilson Disease; Hemophilia; National and International Accreditation; Blood Banking regulations; Distant Testing; Clinical Trials; Medical Tourism; International Reference labs; and Diagnostics in diet.