How Selegiline ((-)-Deprenyl) Slows Brain Aging PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download How Selegiline ((-)-Deprenyl) Slows Brain Aging PDF full book. Access full book title How Selegiline ((-)-Deprenyl) Slows Brain Aging by Joseph Knoll. Download full books in PDF and EPUB format.
Author: Joseph Knoll Publisher: Bentham Science Publishers ISBN: 1608054705 Category : Medical Languages : en Pages : 161
Book Description
This e-book is a reference on Selegiline ((-)-Deprenyl) effects on the brain. Selegiline, described in thousands of research papers, is registered in over 60 countries. At present, more than one hundred preparations containing selegiline circulate in the global market under different brand names. They are widely used in the treatment of Parkinson's disease, Alzheimer's disease, major depression and as a geroprotective / anti-aging drug. ((-)-Deprenyl) selegiline, the first selective inhibitor of B-type MAO which, in contrast to the known MAO inhibitors, did not potentiate the effect of tyramine but inhibited it. the compound could be combined with levodopa in Parkinson's disease without signs of hypertensive reactions. the DATATOP study in the USA revealed that (-)-deprenyl delayed the onset of disability associated with early, otherwise untreated Parkinson's disease. the age-related decay of the supply of the brain with phenylethylamine (PEA), due to the progressive increase of MAO-B activity in the aging brain, and dopamine, due to the better than average decline of the dopaminergic neuronal activity during the postdevelopmental phase of life, are irresistible biochemical lesions of aging. the speed of deterioration of behavioral performances with the passing of time and longevity depends significantly on the pace of the worsening of these lesions. (-)-Deprenyl, increasing the supply of the brain with PEA and dopamine, counteracts this aging process. Maintenance of male rats from sexual maturity until death on ((-)-deprenyl) delays the age-related loss of the capacity to ejaculate, slows the age-related decline of learning ability and prolongs life. In humans, maintenance from sexual maturity on (-)-deprenyl (1 mg daily) is, for the time being, the most promising prophylactic treatment to fight against the age-related decay of behavioral performances, prolonging life, and preventing or delaying the onset of age-related neurodegenerative diseases such as Parkinson's and Alzheimer's. This e-book is a useful reference for graduate medical students, academic researchers in the field of neuropsychopharmacology, neurophysiology and gerontology and professional research groups in commercial organizations manufacturing selegiline preparations.
Author: Joseph Knoll Publisher: Bentham Science Publishers ISBN: 1608054705 Category : Medical Languages : en Pages : 161
Book Description
This e-book is a reference on Selegiline ((-)-Deprenyl) effects on the brain. Selegiline, described in thousands of research papers, is registered in over 60 countries. At present, more than one hundred preparations containing selegiline circulate in the global market under different brand names. They are widely used in the treatment of Parkinson's disease, Alzheimer's disease, major depression and as a geroprotective / anti-aging drug. ((-)-Deprenyl) selegiline, the first selective inhibitor of B-type MAO which, in contrast to the known MAO inhibitors, did not potentiate the effect of tyramine but inhibited it. the compound could be combined with levodopa in Parkinson's disease without signs of hypertensive reactions. the DATATOP study in the USA revealed that (-)-deprenyl delayed the onset of disability associated with early, otherwise untreated Parkinson's disease. the age-related decay of the supply of the brain with phenylethylamine (PEA), due to the progressive increase of MAO-B activity in the aging brain, and dopamine, due to the better than average decline of the dopaminergic neuronal activity during the postdevelopmental phase of life, are irresistible biochemical lesions of aging. the speed of deterioration of behavioral performances with the passing of time and longevity depends significantly on the pace of the worsening of these lesions. (-)-Deprenyl, increasing the supply of the brain with PEA and dopamine, counteracts this aging process. Maintenance of male rats from sexual maturity until death on ((-)-deprenyl) delays the age-related loss of the capacity to ejaculate, slows the age-related decline of learning ability and prolongs life. In humans, maintenance from sexual maturity on (-)-deprenyl (1 mg daily) is, for the time being, the most promising prophylactic treatment to fight against the age-related decay of behavioral performances, prolonging life, and preventing or delaying the onset of age-related neurodegenerative diseases such as Parkinson's and Alzheimer's. This e-book is a useful reference for graduate medical students, academic researchers in the field of neuropsychopharmacology, neurophysiology and gerontology and professional research groups in commercial organizations manufacturing selegiline preparations.
Author: Publisher: Elsevier ISBN: 9780080537412 Category : Medical Languages : en Pages : 224
Book Description
Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most divers and rapidly advancing fields in the life sciences. Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological, and therapeutic aspects of chosen research areas.
Author: Peter Riederer Publisher: Springer Nature ISBN: 303062059X Category : Medical Languages : en Pages : 4652
Book Description
This book provides a reference guide describing the current status of medication in all major psychiatric and neurological indications, together with comparisons of pharmacological treatment strategies in clinical settings in Europe, USA, Japan and China. In addition, it highlights herbal medicine as used in China and Japan, as well as complementary medicine and nutritional aspects. This novel approach offers international readers a global approach in a single dedicated publication and is also a valuable resource for anyone interested in comparing treatments for psychiatric disorders in three different cultural areas. There are three volumes devoted to Basic Principles and General Aspects, offering a general overview of psychopharmacotherapy (Vol. 1); Classes, Drugs and Special Aspects covering the role of psychotropic drugs in the field of psychiatry and neurology (Vol. 2) and Applied Psychopharmacotherapy focusing on applied psychopharmacotherapy (Vol. 3). These books are invaluable to psychiatrists, neurologists, neuroscientists, medical practitioners and clinical psychologists.
Author: Abhilash K. Desai Publisher: Elsevier Health Sciences ISBN: 1455700320 Category : Medical Languages : en Pages : 180
Book Description
This issue examines what is a healthy aging brain and covers preventive measures for succesful cognitive aging. Topics covered include: A road map to healthy aging brain; Cardiovascular risk factors, cerebrovascular disease burden and healthy aging brain; Healthy aging brain: Impact of head injury, alcohol and environmental toxins; Healthy aging brain: What has sleep go to do with it?; Endocrine aspects of healthy aging brain; Healthy aging brain: Role of exercise and physically active lifestyle; Healthy aging brain: Role of nutrition and nutritional supplements; Healthy aging brain: Role of cognitive reserve, cognitive stimulation and cognitive exercises; Healthy aging brain: Impact of positive and negative emotions; Dementia risk predictor. Are we there yet?; Potential future neuroprotective therapies for neurodegenerative disorders and stroke; Healthy aging brain: Importance of promoting resilience and creativity.
Author: Y.L. Wright M.A. Publisher: Lulu.com ISBN: 0359071309 Category : Health & Fitness Languages : en Pages : 276
Book Description
Get Smart with KETO SMART! Heal your brain and heal your body with this easy KETO SMART program. KETO SMART is packed with secrets to improve your memory and thinking with simple instructions that you can easily follow. Learn how to radically improve the health of your brain, so that you can enjoy life to the max at any age. Your heart, arteries, and everything else will improve as well. The KETO SMART 10-step protocol is MUCH more than just following a ketogenic diet. The KETO SMART 10-step protocol is a comprehensive program of self-healing. Follow the KETO SMART ten easy action steps, and soon your thinking mind will become as penetrating as the depths of a pristine alpine lake on a quiet sunny morning. The goal of this book is to guide you through the maze of interconnected problems. Every step helps, but you only get the gold ring of health by following the complete treatment plan. It isnÕt hard if you know what to do. It is impossible if you don't.
Author: J.W. Langston Publisher: IOS Press ISBN: 1614993327 Category : Medical Languages : en Pages : 264
Book Description
In the summer of 1982, hospital emergency rooms in the San Francisco Bay Area were suddenly confronted with mysteriously “frozen” patients – young men and women who, though conscious, could neither move nor speak. Doctors were baffled, until neurologist J. William Langston, recognizing the symptoms of advanced Parkinson’s disease, administered L-dopa – the only known effective treatment – and “unfroze” his patient. Dr. Langston determined that this patient and five others had all used the same tainted batch of synthetic heroin, inadvertently laced with a toxin that had destroyed an area of their brains essential to normal movement. This same area, the substantia nigra, slowly deteriorates in Parkinson’s disease. As scientists raced to capitalize on this breakthrough, Dr. Langston struggled to salvage the lives of his frozen patients, for whom L-dopa provided only short-term relief. The solution he found lay in the most daring area of research: fetal-tissue transplants. The astonishing recovery of two of his patients garnered worldwide press coverage, helped overturn federal restrictions on fetal-tissue research, and offered hope to millions suffering from Parkinson’s, Alzheimer’s, and other degenerative brain disorders. This is the story behind the headline – a spellbinding account that brings to life the intellectual excitement, ethical dilemmas, and fierce competitiveness of medical research. This new updated edition of the classic neurological mystery tale, “The Case of the Frozen Addicts,” illuminates how the solution to a baffling mystery of the brain’s chemistry opened a new frontier in medicine and restored life to people without hope. “It begins with a series of quixotic discoveries, escalates to providing possible solutions for one of humanity’s most intractable medical problems, and then catapults the reader into the center of America’s hottest political arena – abortion and fetal sanctity. Bravo! A brilliant read.” – Laurie Garrett, author of The Coming Plague “[Langston and Palfreman] weave a highly readable and spellbinding medical detective tale... It is as absorbing as a good mystery, as entertaining as an exciting novel, and as enlightening as a good biography.” – Stanley Fahn, New England Journal of Medicine “I could not put it down... it is the lives of the ‘frozen addicts’ themselves – and the fullness with which this is presented – which makes the whole thing overwhelming.” – Oliver Sacks
Author: Frank J. Ayd Publisher: Lippincott Williams & Wilkins ISBN: 9780781724685 Category : Medical Languages : en Pages : 1138
Book Description
Now in its thoroughly updated Second Edition, Dr. Ayd's highly acclaimed Lexicon is an indispensable desk reference for anyone working in psychiatry, neurology, or the underlying basic neurosciences. It provides succinct, detailed, and easily accessible definitions for the entire range of terms currently used in these fields, including drug categories, receptors, and the sites and mechanisms affected by pharmacologic treatments. This edition reflects the most recent developments in genetics and in psychopharmacology, including new drugs and current concepts on drug-drug interactions. Dr. Ayd has added over 1,000 new terms and rewritten nearly half of the entries in the original edition. Compatibility: BlackBerry(R) OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile(TM) Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC
Author: Dr. Hiroshi Demura Publisher: iUniverse ISBN: 1450255760 Category : Health & Fitness Languages : en Pages : 376
Book Description
As we grow older, many of us experience a tremendous amount of frustration because something inside us doesnt work the way it used to. Nutrition experts tell us to eat certain kinds of food some claim free radicals are the sole cause of aging, and that the only way to longevity is through antioxidant supplements. Fitness gurus tell us the only answer is exercise. When we do exercise or go on a diet, we feel a little betterbut not much, and not the way we felt when we were younger. We exercise or diet twice as much to stay at the same place, and even that is a challenge. The story has been the same throughout history, so we wonder if we should continue to fight the battle, or if we should just learn to grow old gracefully. Improvements in medical technology and new knowledge about exercise, nutrition, and rest are all part of the solution to remaining young and healthy. However, we continue to see some people who do not take particularly good care of themselves, yet are aging more gentlyand we know instinctively that parts of the anti-aging puzzle must still be missing.
Author: Joseph Knoll
Author: Joseph Knoll
Author: Alastair Dow
Author: 
Author: 
Author: Peter Riederer
Author: Abhilash K. Desai
Author: Y.L. Wright M.A.
Author: J.W. Langston
Author: Frank J. Ayd
Author: Dr. Hiroshi Demura