The NINCDS Parkinson's Disease Research Program PDF Download

Author: National Institute of Neurological and Communicative Disorders and Stroke
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 12

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Book Description

Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 8

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Book Description

Author: National Institute of Neurological Diseases and Stroke
Publisher:
ISBN:
Category : Parkinson's disease
Languages : en
Pages : 8

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Book Description

Author: National Institute of Neurological and Communicative Disorders and Stroke
Publisher:
ISBN:
Category : Parkinson's disease
Languages : en
Pages : 12

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Book Description

Author: National Institute of Neurological and Communicative Disorders and Stroke
Publisher:
ISBN:
Category : Parkinson's disease
Languages : en
Pages : 12

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Book Description

Author: Marianne J. Willow
Publisher:
ISBN:
Category : Brain
Languages : en
Pages : 130

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Book Description

Author:
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Category : Government publications
Languages : en
Pages : 1180

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Book Description

Author: K. Ray Chaudhuri
Publisher: Oxford University Press, USA
ISBN: 0199684243
Category : Medical
Languages : en
Pages : 517

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Book Description
Patients with Parkinson's disease (PD) are known to suffer from motor symptoms of the disease, but they also experience non-motor symptoms (NMS) that are often present before diagnosis or that inevitably emerge with disease progression. The motor symptoms of Parkinson's disease have been extensively researched, and effective clinical tools for their assessment and treatment have been developed and are readily available. In contrast, researchers have only recently begun to focus on the NMS of Parkinson's Disease, which are poorly recognized and inadequately treated by clinicians. The NMS of PD have a significant impact on patient quality of life and mortality and include neuropsychiatric, sleep-related, autonomic, gastrointestinal, and sensory symptoms. While some NMS can be improved with currently available treatments, others may be more refractory and will require research into novel (non-dopaminergic) drug therapies for the future. Edited by members of the UK Parkinson's Disease Non-Motor Group (PD-NMG) and with contributions from international experts, this new edition summarizes the current understanding of NMS symptoms in Parkinson's disease and points the way towards future research.

Author:
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 1426

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Book Description

Author: Forum on Neuroscience and Nervous System Disorders
Publisher: National Academies Press
ISBN: 9780309285674
Category : Medical
Languages : en
Pages : 0

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Book Description
Neurodegeneration: Exploring Commonalities Across Diseases is the summary of a workshop hosted by the Institute of Medicine\'s (IOM\'s) Forum on Neuroscience and Nervous System Disorders in Spring 2012 to explore commonalities across neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD). Participants from academia; pharmaceutical and biotechnology industries; government agencies such as the National Institutes of Health and the U.S. Department of Veterans Affairs (VA); patient advocacy groups; and private foundations presented and identified potential opportunities for collaboration across the respective research and development communities. This report identifies and discusses commonalities related to genetic and cellular mechanisms, identifies areas of fundamental science needed to facilitate therapeutics development, and explores areas of potential collaboration among the respective research communities. Neurodegenerative diseases, such as Alzheimer\'s disease, Parkinson\'s disease, ALS, and FTD, are becoming increasingly prevalent in the United States due to an aging population. Implications are grave for quality of life and health care costs. Research on neurodegenerative diseases has expanded greatly over the past four decades. Nevertheless, fundamental questions remain about the biology of these diseases, and further insights into the mechanisms of these diseases would help to inform the development of effective means to prevent and to efficiently treat them. Recent findings have revealed certain commonalities in genetic and cellular mechanisms across neurodegenerative diseases. These findings suggest that it might be valuable - at least in some cases - to change the traditional way of studying these diseases by no longer seeing each as an independent entity, but rather as clinical variants of common cellular and molecular biological defects. This approach could help enhance basic scientific understanding of neurodegenerative disease, and could help with the development of biomarkers and new therapeutics.