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Author: Ralf Henkel Publisher: Academic Press ISBN: 0128125675 Category : Medical Languages : en Pages : 324
Book Description
Oxidants, Antioxidants and Impact of the Oxidative Status in Male Reproduction is an essential reference for fertility practitioners and research and laboratory professionals interested in learning about the role of reactive oxygen species in sperm physiology and pathology. The book focuses on unravelling the pathophysiology of oxidative stress mediated male infertility, recruiting top researchers and clinicians to contribute chapters. This collection of expertise delves into the physico-chemical aspects of oxidative stress, including a new focus on reductive stress. Furthermore, the inclusion of clinical techniques to determine oxidative stress and the OMICS of reductive oxidative stress are also included. This is a must-have reference in the area of oxidative stress and male reproductive function. Offers comprehensive information on oxidative stress and its role in male reproduction, including new therapeutic approaches Deals with current approaches to oxidative stress using OMICS platform“/li> Designed for fertility practitioners, reproductive researchers, and laboratory professionals interested in learning about the role of reactive oxygen species in sperm physiology and pathology
Author: Ralf Henkel Publisher: Academic Press ISBN: 0128125675 Category : Medical Languages : en Pages : 324
Book Description
Oxidants, Antioxidants and Impact of the Oxidative Status in Male Reproduction is an essential reference for fertility practitioners and research and laboratory professionals interested in learning about the role of reactive oxygen species in sperm physiology and pathology. The book focuses on unravelling the pathophysiology of oxidative stress mediated male infertility, recruiting top researchers and clinicians to contribute chapters. This collection of expertise delves into the physico-chemical aspects of oxidative stress, including a new focus on reductive stress. Furthermore, the inclusion of clinical techniques to determine oxidative stress and the OMICS of reductive oxidative stress are also included. This is a must-have reference in the area of oxidative stress and male reproductive function. Offers comprehensive information on oxidative stress and its role in male reproduction, including new therapeutic approaches Deals with current approaches to oxidative stress using OMICS platform“/li> Designed for fertility practitioners, reproductive researchers, and laboratory professionals interested in learning about the role of reactive oxygen species in sperm physiology and pathology
Author: Sijo J. Parekattil Publisher: Springer Nature ISBN: 3030323005 Category : Health & Fitness Languages : en Pages : 895
Book Description
A groundbreaking contribution to the literature now in its revised and expanded second edition, this textbook offers a comprehensive review of diagnostic and treatment techniques for male infertility. This state-of-the-art, evidence-based textbook incorporates new multidisciplinary and complementary medicine approaches to create a first-of-its-kind guide to treatment strategies for male infertility and beyond. While this new edition is primarily designed as a reference for students and residents in reproductive medicine and andrology, it will be equally useful as well for professionals in urology, reproductive endocrinology, embryology, and research fields who are interested in the role that antioxidants play in male infertility. World-renowned experts in these areas have been selected to participate in this work. Careful selection of the highest quality content will span the whole range of topics in the area of male infertility, providing a complete review of well-established and current diagnostic and treatment techniques for male infertility. The incorporation of 20 new chapters will enhance the book’s appeal by including the most recent advances brought to the male infertility arena. Additionally, this edition incorporates new features, including bulleted key points, review criteria and select video clips demonstrating some of the most fascinating male infertility treatment modalities. A dedicated new section on current guidelines on male infertility will enlighten readers on how to most optimally manage male infertility clinical scenarios. Covering all aspects of diagnosis and management, ART, lifestyle factors and associated conditions for male infertility, Male Infertility: Contemporary Clinical Approaches, Andrology, ART and Antioxidants will be a readily accessible, high quality reference for medical students and residents, and will be of significant value to professionals working in the various fields treating this condition as well.
Author: RAJENDER SINGH Publisher: Springer ISBN: 9811040176 Category : Medical Languages : en Pages : 497
Book Description
This book covers the latest research on male infertility. The topics discussed range from understanding the genetic basis of infertility, to its causes and treatment. Since infertility is also of great interest to the general public, the book also includes a detailed description of what infertility is and how one can understand the different types. Given the complex etiology of infertility, the book includes a number of chapters defining the known and probable causes of male infertility. Providing detailed information suitable for patients and clinicians alike, it also features a separate section on treatment, the ultimate goal.
Author: Kavindra Kumar Kesari Publisher: Springer Nature ISBN: 3030893405 Category : Medical Languages : en Pages : 384
Book Description
This book discusses the role of oxidative stress in human reproduction with a focus on men’s health. The physiological roles of reactive oxygen species (ROS) in male fertility are the focus in this book. This topic is important because oxidative stress is a result of the imbalance between ROS and antioxidants in the body which may lead to sperm damage (DNA or count), deformity, and eventually, male infertility. Therefore, for a better understanding of the molecular mechanisms related to male genotoxicity and its regulation in infertility, this book provides an up-to-date view on the impact of oxidative stress factors in male reproduction . The main aim of this book is to collect a series of research articles and reviews from a diverse group of scientists to share their research work on the role of ROS or oxidative stress in physiological and pathological states in relation to (in)fertility in the male. This book presents various state-of-the-art chapters of the recent progress in the field of cellular toxicology and clinical manifestations of various issues related to men’s health and fertility. Topics include cell signaling, DNA damage and infertility, the pathophysiology of disease instigation and distribution, immune toxicity and prevention.
Author: Shubhadeep Roychoudhury Publisher: Springer Nature ISBN: 3031129660 Category : Medical Languages : en Pages : 347
Book Description
Volume Two advances the exploration of the fundamental principles of oxidative stress and toxicity on male (and female) reproduction. It includes the advances in research on male reproductive health, the impact of environmental factors, the protective measures using bioactive compounds and traditional medicines, and how to limit toxic exposure. It includes coverage of: Oxidative stress and male infertility Environmental stressors and sexual health Heavy metals, pesticides, fine particle toxicity and male reproduction Protective measures against oxidative stress in gametes/embryos by using bioactive compounds/phytomedicines in Assisted Reproductive Technology (ART) Role of reactive oxygen species on female reproduction Radiation and mutagenic factors affecting the male reproductive system Both volumes provide a comprehensive look at the most basic concepts and advanced research being conducted by world famous scientists and researchers in male infertility and reproduction.
Author: Cristian O'Flaherty Publisher: MDPI ISBN: 3039360248 Category : Science Languages : en Pages : 194
Book Description
Reactive oxygen species (ROS) are inevitable by-products of aerobic cells. A delicate balance between ROS production and antioxidant defences is essential to assure cell function. This requirement is also true for the spermatozoon, the male gamete, with the unique goal of carrying and delivering the paternal genome into the oocyte. Oxidative stress promotes damage in lipids, proteins and DNA of spermatozoa, and this oxidative damage is associated with infertility. The ROS-dependent damage could occur at different stages of the production and maturation of the sperm. On the other hand, low and controlled levels of ROS are necessary to trigger and regulate sperm function. When ejaculated, spermatozoa are incapable of fertilizing the egg. They must reside in the oviduct of the female genital tract to undergo a yet to be understood the biochemical process called capacitation. Once capacitated, the spermatozoon undergoes the exocytotic event called acrosome reaction and fertilize the oocyte. ROS regulate the different molecular mechanisms such as sperm motility, capacitation and acrosome reaction to assure fertilization. This Special Issue includes original research and reviews of literature concerning the role of reactive oxygen species in male reproduction, particularly the role of antioxidants in the regulation of male fertility as well as basic and clinical studies using antioxidant-based strategies for the treatment of male infertility.
Author: Ashok Agarwal Publisher: Springer ISBN: 3319267973 Category : Health & Fitness Languages : en Pages : 215
Book Description
This state-of-the-art laboratory manual includes 20 clinical protocols used daily for the investigation of the infertile male, presented with easy to understand, step-by-step methodology. The protocols are arranged from routine to advanced laboratory procedures common to clinical practice, including computer-assisted semen analysis, sperm preparation for IUI by density gradient and swim-up, sperm cryopreservation, and sperm DNA fragmentation test by TUNEL method, among others. The methodology in each protocol follows best practice guidelines made clearer by professionally hand-drawn illustrations covering most of the important steps and equipment. The authors, hailing from the world-renowned Andrology Center at Cleveland Clinic, have over 50 years of combined first-hand experience in managing very busy diagnostic and research facilities in male infertility and andrology. The book will be an indispensable resource for thousands of laboratory technologists, clinicians and reproductive professionals (andrologists, embryologist, etc.) engaged in the diagnosis and management of infertile men around the world.
Author: Ashok Agarwal Publisher: Springer Science & Business Media ISBN: 1617797758 Category : Science Languages : en Pages : 671
Book Description
Studies on Men’s Health and Fertility provides a comprehensive series of up-to-the-minute reviews addressing the role of oxidative stress in the aetiology of reproductive pathologies in the male. This volume represents by far the most detailed, authoritative review of the field that has been produced to date. The text encompasses the basic science of reactive oxygen species (ROS) production by mammalian spermatozoa, the way in which these highly reactive molecules are processed by the germ line and the physiological significance of this redox activity in the generation of a functional gamete. The factors responsible for perturbing the delicate balance between physiological redox signaling on the one hand and oxidative stress on the other are also extensively reviewed and some of the first clues concerning the underlying mechanisms (age, heat, infection, cryostorage, aberrant lipid metabolism), clearly identified. From a clinical perspective there are chapters setting out the methods we should be using to diagnose oxidative stress in the male germ line, a clinical perspective on the aetiology of this condition and detailed considerations of the most suitable means of ameliorating such stress from a therapeutic point of view. Studies on Men’s Health and Fertility is intended to provide clinicians and scientists with a snap shot of the current status of this exciting, rapidly moving field. The book will be of value to clinicians interested in strategies for the management of oxidative stress in their infertility patients and scientists wishing to understand the molecular mechanisms underpinning the generation of ROS by these cells and its pathophysiological significance. It was not so long ago that the ability of spermatozoa to generate ROS was a hotly disputed topic. With the publication of this book such doubts can finally be laid to rest. There is now no doubt that these cells actively generate ROS, that oxidative stress is a major contributor to defects in male reproductive health and that the successful clinical management of this condition depends on developing a deeper understanding of the underlying molecular mechanisms. In this quest, Studies on Men’s Health and Fertility will be seen as a clear and important milestone.
Author: Ralf Henkel
Author: Ralf Henkel
Author: Sijo J. Parekattil
Author: RAJENDER SINGH
Author: Kavindra Kumar Kesari
Author: Shubhadeep Roychoudhury
Author: Cristian O'Flaherty
Author: Falk Rüdiger Ochsendorf
Author: Ashok Agarwal
Author: Ashok Agarwal
Author: Falk Ed. Ochsendorf