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Neuroscience Biomarkers and Biosignatures

Neuroscience Biomarkers and Biosignatures PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309178282
Category : Medical
Languages : en
Pages : 128

Book Description
Biomarkers, or biological markers, are quantitative measurements that offer researchers and clinicians valuable insight into diagnosis, treatment and prognosis for many disorders and diseases. A major goal in neuroscience medical research is establishing biomarkers for disorders of the nervous system. Given the promising potential and necessity for neuroscience biomarkers, the Institute of Medicine Forum on Neuroscience and Nervous System Disorders convened a public workshop and released the workshop summary entitled Neuroscience Biomarkers and Biosignatures: Converging Technologies, Emerging Partnerships. The workshop brought together experts from multiple areas to discuss the most promising and practical arenas in neuroscience in which biomarkers will have the greatest impact. The main objective of the workshop was to identify and discuss biomarker targets that are not currently being aggressively pursued but that could have the greatest near-term impact on the rate at which new treatments are brought forward for psychiatric and neurological disorders.

Neuroscience Biomarkers and Biosignatures

Neuroscience Biomarkers and Biosignatures PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309178282
Category : Medical
Languages : en
Pages : 128

Book Description
Biomarkers, or biological markers, are quantitative measurements that offer researchers and clinicians valuable insight into diagnosis, treatment and prognosis for many disorders and diseases. A major goal in neuroscience medical research is establishing biomarkers for disorders of the nervous system. Given the promising potential and necessity for neuroscience biomarkers, the Institute of Medicine Forum on Neuroscience and Nervous System Disorders convened a public workshop and released the workshop summary entitled Neuroscience Biomarkers and Biosignatures: Converging Technologies, Emerging Partnerships. The workshop brought together experts from multiple areas to discuss the most promising and practical arenas in neuroscience in which biomarkers will have the greatest impact. The main objective of the workshop was to identify and discuss biomarker targets that are not currently being aggressively pursued but that could have the greatest near-term impact on the rate at which new treatments are brought forward for psychiatric and neurological disorders.

Biomarkers of Neurological Diseases

Biomarkers of Neurological Diseases PDF Author: Noah Benge
Publisher: States Academic Press
ISBN: 9781639897896
Category : Health & Fitness
Languages : en
Pages : 0

Book Description
Neurological diseases are disorders of the nervous system that affect the functioning of the brain and the nerves found throughout the human body and the spinal cord. The most common neurological disorders are epilepsy, Alzheimer's disease, migraine, stroke, Parkinson's disease, multiple sclerosis and cerebral palsy. The term biomarker or biological marker refers to a biological molecule found in blood, tissues or other body fluids, which indicates a normal or abnormal process, a condition, or a disease. Biomarkers help to diagnose a disease or condition, or to detect the disease progression, and record the effect of new drugs and therapeutic strategies as they are generated. Neurological biomarkers are used to diagnose a variety of neurological disorders and to monitor the advancement of these diseases or effect of the treatment. This process aids in predicting outcomes, determining interventions, and evaluating the therapeutic responses. This book is compiled in such a manner, that it will provide an in-depth knowledge about neurological biomarkers. It is a vital tool for all researching or studying the biomarkers of neurological diseases.

Biomarkers of Brain Injury and Neurological Disorders

Biomarkers of Brain Injury and Neurological Disorders PDF Author: Kevin K. W. Wang
Publisher: CRC Press
ISBN: 1482239825
Category : Medical
Languages : en
Pages : 652

Book Description
This book explores the recent advances in the techniques and platforms used in biomarker research that have revolutionized the way we study, diagnose, and treat brain injury conditions. The contributors describe different biomarker studies pertaining to brain injury and other neurological disorders and analyze the different models and technologies used to identify these biological markers. The book includes findings from "Omics research" that have been utilized to decipher and identify such biomarkers. It discusses protein, microRNA, and altered gene profiles and reviews neurological disorders such as multiple sclerosis, Charcot-Marie-Tooth disease, and prion and Alzheimer’s disease.

Biomarkers in Neurology

Biomarkers in Neurology PDF Author: Mohamed Mosaad Salama
Publisher: Frontiers Media SA
ISBN: 2889636933
Category :
Languages : en
Pages : 173

Book Description


MicroRNAs in Diseases and Disorders

MicroRNAs in Diseases and Disorders PDF Author: Philip V Peplow
Publisher: Royal Society of Chemistry
ISBN: 1788017811
Category : Science
Languages : en
Pages : 500

Book Description
From pathology to treatment, MicroRNAs in Diseases and Disorders highlights the role of microRNAs (miRNAs) in the development and progression of a variety of diseases, including cancer, neurological disease, endocrine disease and autoimmune disease, and underscores the utilization of miRNA targets in the treatment of these conditions. Providing a comprehensive account, this book also includes the identification of miRNAs as diagnostic and prognostic biomarkers for disease, as well as evaluates translational value from clinical trials using synthesized and functionalized miRNA mimics and inhibitors. With a global contribution list and chapters from leading experts across the field, MicroRNAs in Diseases and Disorders is an invaluable reference to miRNA researchers and health professionals in a variety of disease areas in government, academia and industry. The book will also appeal to pharmaceutical and medicinal chemists with an interest in miRNA targeting therapeutics, as well as to advanced students in chemical biology and drug discovery.

Neuroscience Biomarkers and Biosignatures

Neuroscience Biomarkers and Biosignatures PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309108896
Category : Medical
Languages : en
Pages : 128

Book Description
Biomarkers, or biological markers, are quantitative measurements that offer researchers and clinicians valuable insight into diagnosis, treatment and prognosis for many disorders and diseases. A major goal in neuroscience medical research is establishing biomarkers for disorders of the nervous system. Given the promising potential and necessity for neuroscience biomarkers, the Institute of Medicine Forum on Neuroscience and Nervous System Disorders convened a public workshop and released the workshop summary entitled Neuroscience Biomarkers and Biosignatures: Converging Technologies, Emerging Partnerships. The workshop brought together experts from multiple areas to discuss the most promising and practical arenas in neuroscience in which biomarkers will have the greatest impact. The main objective of the workshop was to identify and discuss biomarker targets that are not currently being aggressively pursued but that could have the greatest near-term impact on the rate at which new treatments are brought forward for psychiatric and neurological disorders.

Biomarkers in Alzheimer's Disease

Biomarkers in Alzheimer's Disease PDF Author: Tapan Khan
Publisher: Academic Press
ISBN: 0128051477
Category : Science
Languages : en
Pages : 276

Book Description
Biomarkers in Alzheimer’s Disease provides a comprehensive overview of all modalities of Alzheimer’s disease biomarkers, including neuroimaging, cerebrospinal fluid, genomic, and peripheral systems. Each chapter integrates molecular/cellular abnormality due to Alzheimer’s disease and technological advancement of biomarkers techniques. The book is ideal for clinical neuroscience and molecular/cellular neuroscience researchers, psychiatrists, and allied healthcare practitioners involved in the diagnosis and management of patients with cognitive impairment and Alzheimer’s disease, and for differential diagnosis of Alzheimer’s disease with other non-Alzheimer’s dementia. Presents a comprehensive overview detailing all modalities of Alzheimer’s disease biomarkers Written for neuroscience researchers and clinicians studying or treating patients with Alzheimer’s Disease Integrates, in each chapter, the molecular/cellular abnormality due to Alzheimer’s disease and the technological advancement of biomarkers techniques

Biomarkers of Neurological and Psychiatric Disease

Biomarkers of Neurological and Psychiatric Disease PDF Author:
Publisher: Academic Press
ISBN: 0123877237
Category : Medical
Languages : en
Pages : 471

Book Description
Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia. Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Pathophysiologic Insights from Biomarker Studies in Neurological Disorders

Pathophysiologic Insights from Biomarker Studies in Neurological Disorders PDF Author: Tobias Ruck
Publisher: Frontiers Media SA
ISBN: 2889636437
Category :
Languages : en
Pages : 340

Book Description


Advanced Biomarkers for Neurological Diseases

Advanced Biomarkers for Neurological Diseases PDF Author: Noah Benge
Publisher: American Medical Publishers
ISBN:
Category : Medical
Languages : en
Pages : 0

Book Description
The diseases of the central or peripheral nervous system are called neurological disorders. These disorders include epilepsy, Alzheimer's disease, and other dementias. Cerebrovascular diseases such as stroke, migraine, multiple sclerosis, Parkinson's disease, etc. are also considered as neurological diseases. A biomarker or biological marker is a cell, tissue, or body fluid cell that can be measured and evaluated to indicate a pharmacological response to a normal biological process, pathogenic process, or therapeutic intervention. Biomarkers characterize the progression of the disease from the earliest natural signs of the disease. Biomarkers assess the disease susceptibility and severity enabling prediction of outcomes, deciding interventions, and assessing the therapeutic responses. Based on clinical applications, biomarkers can be categorized as molecular biomarkers, cellular biomarkers, or imaging biomarkers. This book aims to shed light on some of the unexplored aspects of biomarkers. It presents researches and studies performed by experts across the globe on the topic in detail. It attempts to assist those with a goal of furthering their studies in the field of biomarkers and biomarker development.