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Cell Membrane Nanodomains

Cell Membrane Nanodomains PDF Author: Alessandra Cambi
Publisher: CRC Press
ISBN: 1482209896
Category : Medical
Languages : en
Pages : 514

Book Description
Cell Membrane Nanodomains: From Biochemistry to Nanoscopy describes recent advances in our understanding of membrane organization, with a particular focus on the cutting-edge imaging techniques that are making these new discoveries possible. With contributions from pioneers in the field, the book explores areas where the application of these novel techniques reveals new concepts in biology. It assembles a collection of works where the integration of membrane biology and microscopy emphasizes the interdisciplinary nature of this exciting field. Beginning with a broad description of membrane organization, including seminal work on lipid partitioning in model systems and the roles of proteins in membrane organization, the book examines how lipids and membrane compartmentalization can regulate protein function and signal transduction. It then focuses on recent advances in imaging techniques and tools that foster further advances in our understanding of signaling nanoplatforms. The coverage includes several diffraction-limited imaging techniques that allow for measurements of protein distribution/clustering and membrane curvature in living cells, new fluorescent proteins, novel Laurdan analyses, and the toolbox of labeling possibilities with organic dyes. Since superresolution optical techniques have been crucial to advancing our understanding of cellular structure and protein behavior, the book concludes with a discussion of technologies that are enabling the visualization of lipids, proteins, and other molecular components at unprecedented spatiotemporal resolution. It also explains the ins and outs of the rapidly developing high- or superresolution microscopy field, including new methods and data analysis tools that exclusively pertain to these techniques. This integration of membrane biology and advanced imaging techniques emphasizes the interdisciplinary nature of this exciting field. The array of contributions from leading world experts makes this book a valuable tool for the visualization of signaling nanoplatforms by means of cutting-edge optical microscopy tools.

Cell Membrane Nanodomains

Cell Membrane Nanodomains PDF Author: Alessandra Cambi
Publisher: CRC Press
ISBN: 1482209896
Category : Medical
Languages : en
Pages : 514

Book Description
Cell Membrane Nanodomains: From Biochemistry to Nanoscopy describes recent advances in our understanding of membrane organization, with a particular focus on the cutting-edge imaging techniques that are making these new discoveries possible. With contributions from pioneers in the field, the book explores areas where the application of these novel techniques reveals new concepts in biology. It assembles a collection of works where the integration of membrane biology and microscopy emphasizes the interdisciplinary nature of this exciting field. Beginning with a broad description of membrane organization, including seminal work on lipid partitioning in model systems and the roles of proteins in membrane organization, the book examines how lipids and membrane compartmentalization can regulate protein function and signal transduction. It then focuses on recent advances in imaging techniques and tools that foster further advances in our understanding of signaling nanoplatforms. The coverage includes several diffraction-limited imaging techniques that allow for measurements of protein distribution/clustering and membrane curvature in living cells, new fluorescent proteins, novel Laurdan analyses, and the toolbox of labeling possibilities with organic dyes. Since superresolution optical techniques have been crucial to advancing our understanding of cellular structure and protein behavior, the book concludes with a discussion of technologies that are enabling the visualization of lipids, proteins, and other molecular components at unprecedented spatiotemporal resolution. It also explains the ins and outs of the rapidly developing high- or superresolution microscopy field, including new methods and data analysis tools that exclusively pertain to these techniques. This integration of membrane biology and advanced imaging techniques emphasizes the interdisciplinary nature of this exciting field. The array of contributions from leading world experts makes this book a valuable tool for the visualization of signaling nanoplatforms by means of cutting-edge optical microscopy tools.

Membrane Nanodomains

Membrane Nanodomains PDF Author: John R. Silvius
Publisher: Morgan & Claypool Publishers
ISBN: 1615046208
Category : Science
Languages : en
Pages : 112

Book Description
Many membranes in eukaryotic cells are inhomogeneous structures in which various membrane components are nonrandomly distributed, forming diverse types of 'domains.' Some membrane domains have long been well known, because they are sufficiently large, long-lived, and morphologically well defined to be characterized using classical microscopic and biochemical approaches. However, new technologies have revealed the presence in membranes of smaller, often highly dynamic 'nanodomains' that also play key roles in membrane function. Our current understanding of the diversity, the properties, and the functions of nanodomains is still very limited and, in some cases, controversial. Nonetheless, it is clear that many important aspects of membrane biology arise from features of membrane organization that 'play out' on spatial and temporal scales that are only now becoming experimentally accessible in living systems. In this book, we will discuss properties and interactions of membrane molecules that lead to nanodomain formation, new and emerging technologies by which nanodomains can be studied, and experimental examples that illustrate both highlights and current limitations of our present knowledge of the properties of membrane nanodomains in various cell types.

Cell Membrane Nanodomains

Cell Membrane Nanodomains PDF Author: Alessandra Cambi
Publisher: CRC Press
ISBN: 1482209918
Category : Medical
Languages : en
Pages : 510

Book Description
Cell Membrane Nanodomains: From Biochemistry to Nanoscopy describes recent advances in our understanding of membrane organization, with a particular focus on the cutting-edge imaging techniques that are making these new discoveries possible. With contributions from pioneers in the field, the book explores areas where the application of these novel techniques reveals new concepts in biology. It assembles a collection of works where the integration of membrane biology and microscopy emphasizes the interdisciplinary nature of this exciting field. Beginning with a broad description of membrane organization, including seminal work on lipid partitioning in model systems and the roles of proteins in membrane organization, the book examines how lipids and membrane compartmentalization can regulate protein function and signal transduction. It then focuses on recent advances in imaging techniques and tools that foster further advances in our understanding of signaling nanoplatforms. The coverage includes several diffraction-limited imaging techniques that allow for measurements of protein distribution/clustering and membrane curvature in living cells, new fluorescent proteins, novel Laurdan analyses, and the toolbox of labeling possibilities with organic dyes. Since superresolution optical techniques have been crucial to advancing our understanding of cellular structure and protein behavior, the book concludes with a discussion of technologies that are enabling the visualization of lipids, proteins, and other molecular components at unprecedented spatiotemporal resolution. It also explains the ins and outs of the rapidly developing high- or superresolution microscopy field, including new methods and data analysis tools that exclusively pertain to these techniques. This integration of membrane biology and advanced imaging techniques emphasizes the interdisciplinary nature of this exciting field. The array of contributions from leading world experts makes this book a valuable tool for the visualization of signaling nanoplatforms by means of cutting-edge optical microscopy tools.

Advances in Planar Lipid Bilayers and Liposomes

Advances in Planar Lipid Bilayers and Liposomes PDF Author: A. Leitmannova Liu
Publisher: Academic Press
ISBN: 9780080888668
Category : Science
Languages : en
Pages : 206

Book Description
Advances in Planar Lipid Bilayers and Liposomes, Volume 10, continues to include invited chapters on a broad range of topics, covering the main arrangements of the reconstituted system, namely planar lipid bilayers and spherical liposomes. The invited authors present the latest results in this exciting multidisciplinary field of their own research group. Many of the contributors working in both fields over many decades were in close collaboration with the late Prof. H. Ti Tien, the founding editor of this book series. There are also chapters written by some of the younger generation of scientists included in this series. This volume keeps in mind the broader goal with both systems, planar lipid bilayers and spherical liposomes, which is the further development of this interdisciplinary field worldwide. * Incorporates contributions from newcomers and established and experienced researchers * Explores the planar lipid bilayer systems and spherical liposomes from both theoretical and experimental perspectives * Serves as an indispensable source of information for new scientists

Nanostructures in Biological Systems

Nanostructures in Biological Systems PDF Author: Aleš Iglič
Publisher: CRC Press
ISBN: 9814303437
Category : Medical
Languages : en
Pages : 534

Book Description
This book is a survey on the theoretical as well as experimental results on nanostructures in biological systems. It shows how a unifying approach starting from single-particle energy, deriving free energy of the system and determining the equilibrium by minimizing the free energy, can be applied to describe electrical and elastic phenomena. It helps the readers to use this basic, transparent, and simple approach to develop additional new systems and interactions and describes the theoretical and experimental aspects together so that they support each other in broadening the knowledge on biological systems. It suggests potential use of this knowledge in clinically relevant phenomena such as hemostasis, inflammation, and spreading of cancer and describes some applications in nanotoxicology, such as the interactions between biological membranes and inorganic nanostructures.

Cell Membrane Nanodomains

Cell Membrane Nanodomains PDF Author: Taylor & Francis Group
Publisher: CRC Press
ISBN: 9781032236742
Category :
Languages : en
Pages : 510

Book Description
This book furthers the readers' understanding of the fundamental molecular mechanisms that govern nanostructures and protein function relationships at the cell membrane and explains the ins and outs of this rapidly developing high- or super-resolution microscopy field. Contributing writers include experts from the optical nanoscopy and microscop

Molecular Organization of Membranes: Where Biology Meets Biophysics

Molecular Organization of Membranes: Where Biology Meets Biophysics PDF Author: Marek Cebecauer
Publisher: Frontiers Media SA
ISBN: 2889454096
Category :
Languages : en
Pages : 150

Book Description
Biological membranes protect cells and organelles from the surrounding environment, but serve also as organising platforms for physiological processes such as cell signalling. The hydrophobic core of membranes is composed of lipids and proteins influencing each other. Local membrane composition and properties define its molecular organisation and, in this way, regulate the function of all associated molecules. Therefore, studying interactions of components, biophysical properties and overall membrane dynamics provides essential information on its function in the context of cell activities. Such knowledge can contribute to biomedical fields such as pharmacology, immunology, neurobiology and many others. The goal of the Research Topic entitled ‘Molecular organisation of membranes: where biology meets biophysics’ was to provide a comprehensive platform for publishing articles, reviews and opinions focused on membrane organisation and the forces behind its heterogeneous and dynamic structure. We collected 11 works which cover topics as diverse as general membrane organisation models, membrane trafficking and signalling regulation, biogenesis of caveolae, protein-lipid interactions and the importance of membrane-associated tetraspanins networks. The prevalent theme was the existence of membrane nanodomains. To this point, new emerging technologies are presented which own the power to bring a novel insight on how membrane nanodomains are formed and maintained and what is their function. We believe that the collection of works in this Research Topic brings forward some important questions which will stimulate further research in this difficult but exciting field.

Functional Heterogeneities in Biomembranes

Functional Heterogeneities in Biomembranes PDF Author: Rainer A. Böckmann
Publisher: Frontiers Media SA
ISBN: 2889712486
Category : Science
Languages : en
Pages : 372

Book Description


Regulation of Nitrogen-Fixing Symbioses in Legumes

Regulation of Nitrogen-Fixing Symbioses in Legumes PDF Author:
Publisher: Academic Press
ISBN: 0081027990
Category : Science
Languages : en
Pages : 364

Book Description
The Nitrogen-Fixing Legume-Rhizobium Symbiosis, Volume 94, the latest release in the Advances in Botanical Research series, highlights new advances in the field, with this new volume presenting interesting chapters on The diversity of legume-rhizobium symbioses, Parasponia; an evolutionary outlier of rhizobium symbiosis, Rhizobium diversity in the light of evolution, Genomes of rhizobia, Gene regulation by extracytoplasmic function (ECF) sigma factors in alpha-rhizobia, Early symbiotic signaling between Plant and Bacteria, Rhizobia infection, a journey to the inside of plant cells, Differentiation of symbiotic nodule cells and their rhizobium endosymbionts, Nodule Organogenesis, Nitrogen Fixation by the Legume-Rhizobium Symbiosis, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Advances in Botanical Research series Updated release includes the latest information on the Nitrogen-Fixing Legume-Rhizobium Symbiosis

Biology and Mechanics of Blood Flows

Biology and Mechanics of Blood Flows PDF Author: Marc Thiriet
Publisher: Springer Science & Business Media
ISBN: 0387748474
Category : Science
Languages : en
Pages : 658

Book Description
This authoritative work presents the basic knowledge and state-of-the-art techniques necessary to carry out investigations of the cardiovascular system using modeling and simulation. The book provides a survey of relevant cell components and processes, with detailed coverage of the electrical and mechanical behaviors of vascular cells, tissues, and organs. Biological and mechanical glossaries are provided.