Biostatistics for Radiologists PDF Download

Author: Francesco Sardanelli
Publisher: Springer Science & Business Media
ISBN: 8847011337
Category : Medical
Languages : en
Pages : 244

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Book Description
The aim of this book is to present statistical problems and methods in a friendly way to radiologists, emphasizing statistical issues and methods most frequently used in radiological studies (e.g., nonparametric tests, analysis of intra- and interobserver reproducibility, comparison of sensitivity and specificity among different imaging modality, difference between clinical and screening application of diagnostic tests, ect.). The tests will be presented starting from a radiological "problem" and all examples of statistical methods applications will be "radiological".

Author: Andrea S. Doria
Publisher: Thieme
ISBN: 1604068272
Category : Medical
Languages : en
Pages : 555

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Book Description
Research Methods in Radiology provides concise, practical insights on how to design clinical and experimental studies in diagnostic imaging. This unique resource encompasses contributions from leaders in academic radiology as well as top epidemiologists, biostatisticians, and librarians with vast multidisciplinary and radiology research experience. The material reflects years of expertise teaching core biostatistics in radiology principles to residents, fellows, radiologists, and epidemiologists. Given the vast amount of published information on research methodology and statistics in radiology, the authors' goal was to write a high-yield review and study tool rather than a comprehensive book. Key topics are succinctly addressed in each chapter, including measurements in radiology; decision analysis in radiology; and systemic reviews, evidence-based imaging, and knowledge translation. Online exercises related to each topic enable residents to prepare for radiology board examinations and research radiologists to apply knowledge to clinical studies. Key Highlights Introductory chapters on analysis of diagnostic tests, linear and logistic regression, meta-analysis, statistical inference, and economic evaluation provide easy-to-follow tutorials Each chapter includes learning objectives, basic concepts, supplementary tables, and ancillary online material Case studies with images, graphs, and tables highlight primary "take home" points Sample size calculations are illustrated for a wide range of research questions Code is included for use in R, free open-source software for statistical analysis This book is an indispensable review of research methodology for radiology students and residents. Practicing clinicians will also benefit from this precisely focused reference tool on clinical and experimental research.

Author: Kelly H. Zou
Publisher: CRC Press
ISBN: 1439812233
Category : Mathematics
Languages : en
Pages : 245

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Book Description
Statistical evaluation of diagnostic performance in general and Receiver Operating Characteristic (ROC) analysis in particular are important for assessing the performance of medical tests and statistical classifiers, as well as for evaluating predictive models or algorithms. This book presents innovative approaches in ROC analysis, which are relevant to a wide variety of applications, including medical imaging, cancer research, epidemiology, and bioinformatics. Statistical Evaluation of Diagnostic Performance: Topics in ROC Analysis covers areas including monotone-transformation techniques in parametric ROC analysis, ROC methods for combined and pooled biomarkers, Bayesian hierarchical transformation models, sequential designs and inferences in the ROC setting, predictive modeling, multireader ROC analysis, and free-response ROC (FROC) methodology. The book is suitable for graduate-level students and researchers in statistics, biostatistics, epidemiology, public health, biomedical engineering, radiology, medical imaging, biomedical informatics, and other closely related fields. Additionally, clinical researchers and practicing statisticians in academia, industry, and government could benefit from the presentation of such important and yet frequently overlooked topics.

Author: Lyle D. Broemeling
Publisher: CRC Press
ISBN: 9781584887683
Category : Mathematics
Languages : en
Pages : 216

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Book Description
There are numerous advantages to using Bayesian methods in diagnostic medicine, which is why they are employed more and more today in clinical studies. Exploring Bayesian statistics at an introductory level, Bayesian Biostatistics and Diagnostic Medicine illustrates how to apply these methods to solve important problems in medicine and biology. After focusing on the wide range of areas where diagnostic medicine is used, the book introduces Bayesian statistics and the estimation of accuracy by sensitivity, specificity, and positive and negative predictive values for ordinal and continuous diagnostic measurements. The author then discusses patient covariate information and the statistical methods for estimating the agreement among observers. The book also explains the protocol review process for cancer clinical trials, how tumor responses are categorized, how to use WHO and RECIST criteria, and how Bayesian sequential methods are employed to monitor trials and estimate sample sizes. With many tables and figures, this book enables readers to conduct a Bayesian analysis for a large variety of interesting and practical biomedical problems.

Author: Wayne W. Daniel
Publisher: Wiley
ISBN: 1119282373
Category : Medical
Languages : en
Pages : 720

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Book Description
The ability to analyze and interpret enormous amounts of data has become a prerequisite for success in allied healthcare and the health sciences. Now in its 11th edition, Biostatistics: A Foundation for Analysis in the Health Sciences continues to offer in-depth guidance toward biostatistical concepts, techniques, and practical applications in the modern healthcare setting. Comprehensive in scope yet detailed in coverage, this text helps students understand—and appropriately use—probability distributions, sampling distributions, estimation, hypothesis testing, variance analysis, regression, correlation analysis, and other statistical tools fundamental to the science and practice of medicine. Clearly-defined pedagogical tools help students stay up-to-date on new material, and an emphasis on statistical software allows faster, more accurate calculation while putting the focus on the underlying concepts rather than the math. Students develop highly relevant skills in inferential and differential statistical techniques, equipping them with the ability to organize, summarize, and interpret large bodies of data. Suitable for both graduate and advanced undergraduate coursework, this text retains the rigor required for use as a professional reference.

Author: Hani H. Abujudeh
Publisher: OUP USA
ISBN: 0199735751
Category : Medical
Languages : en
Pages : 373

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Book Description
Radiology has been transformed by new imaging advances and a greater demand for imaging, along with a much lower tolerance for error as part of the Quality & Safety revolution in healthcare. With a greater emphasis on patient safety and quality in imaging practice, imaging specialists are increasingly charged with ensuring patient safety and demonstrating that everything done for patients in their care meets the highest quality and safety standards. This book offers practical guidance on understanding, creating, and implementing quality management programs in Radiology. Chapters are comprehensive, detailed, and organized into three sections: Core Concepts, Management Concepts, and Educational & Special Concepts. Discussions are applicable to all practice settings: community hospitals, private practice, academic radiology, and government/military practice, as well as to those preparing for the quality and safety questions on the American Board of Radiology's "Maintenance of Certification" or initial Board Certification Examinations. Bringing together the various elements that comprise the quality and safety agenda for Radiology, this book serves as a thorough roadmap and resource for radiologists, technicians, and radiology managers and administrators.

Author: Joseph C. Cappelleri
Publisher: CRC Press
ISBN: 1439873674
Category : Mathematics
Languages : en
Pages : 354

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Book Description
Advancing the development, validation, and use of patient-reported outcome (PRO) measures, Patient-Reported Outcomes: Measurement, Implementation and Interpretation helps readers develop and enrich their understanding of PRO methodology, particularly from a quantitative perspective. Designed for biopharmaceutical researchers and others in the health sciences community, it provides an up-to-date volume on conceptual and analytical issues of PRO measures. The book discusses key concepts relating to the measurement, implementation, and interpretation of PRO measures. It covers both introductory and advanced psychometric and biostatistical methods for constructing and analyzing PRO measures. The authors include many relevant real-life applications based on their extensive first-hand experiences in the pharmaceutical industry. They implement a wealth of simulated datasets to illustrate concepts and heighten understanding based on practical scenarios. For readers interested in conducting statistical analyses of PRO measures and delving more deeply into the analytic details, most chapters contain SAS code and output that illustrate the methodology. Along with providing numerous references, the book highlights current regulatory guidelines.

Author: David M. Yousem
Publisher: Elsevier Health Sciences
ISBN: 0323473741
Category : Medical
Languages : en
Pages : 227

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Book Description
The only review book of its kind, David M. Yousem’s Non-Interpretive Skills prepares you for exam questions on every aspect of radiology that does not involve reading and interpreting images: communication, quality and safety, ethics, leadership, data management, business principles, analytics, statistics, and more. Ideal for residents and practitioners alike, this unique study tool contains hundreds of questions, answers, and rationales that cover the entire range of NIS content on the credentialing boards and MOC exams. Your exam preparation isn’t complete without it! Exclusive test preparation on every NIS area, including business, ethics, safety, quality improvement, resuscitation techniques, and medications used by radiologists. 600 multiple-choice questions with answers and rationales provide a practical and solid foundation for exams and clinical practice. Author David M. Yousem, MD, MBA and his colleagues at the Johns Hopkins Department of Radiology share years of expertise in radiology education, quality assurance, and business topics. A single, easy-to-use source for thorough review of the NIS topics you’ll encounter on exams and in your radiology practice.

Author: Ruijiang Li
Publisher: CRC Press
ISBN: 1351208268
Category : Science
Languages : en
Pages : 420

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Book Description
Radiomics and Radiogenomics: Technical Basis and Clinical Applications provides a first summary of the overlapping fields of radiomics and radiogenomics, showcasing how they are being used to evaluate disease characteristics and correlate with treatment response and patient prognosis. It explains the fundamental principles, technical bases, and clinical applications with a focus on oncology. The book’s expert authors present computational approaches for extracting imaging features that help to detect and characterize disease tissues for improving diagnosis, prognosis, and evaluation of therapy response. This book is intended for audiences including imaging scientists, medical physicists, as well as medical professionals and specialists such as diagnostic radiologists, radiation oncologists, and medical oncologists. Features Provides a first complete overview of the technical underpinnings and clinical applications of radiomics and radiogenomics Shows how they are improving diagnostic and prognostic decisions with greater efficacy Discusses the image informatics, quantitative imaging, feature extraction, predictive modeling, software tools, and other key areas Covers applications in oncology and beyond, covering all major disease sites in separate chapters Includes an introduction to basic principles and discussion of emerging research directions with a roadmap to clinical translation

Author: Xiao-Hua Zhou
Publisher: John Wiley & Sons
ISBN: 1118626044
Category : Medical
Languages : en
Pages : 592

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Book Description
Praise for the First Edition " . . . the book is a valuable addition to the literature in thefield, serving as a much-needed guide for both clinicians andadvanced students."—Zentralblatt MATH A new edition of the cutting-edge guide to diagnostic tests inmedical research In recent years, a considerable amount of research has focusedon evolving methods for designing and analyzing diagnostic accuracystudies. Statistical Methods in Diagnostic Medicine, Second Editioncontinues to provide a comprehensive approach to the topic, guidingreaders through the necessary practices for understanding thesestudies and generalizing the results to patient populations. Following a basic introduction to measuring test accuracy andstudy design, the authors successfully define various measures ofdiagnostic accuracy, describe strategies for designing diagnosticaccuracy studies, and present key statistical methods forestimating and comparing test accuracy. Topics new to the SecondEdition include: Methods for tests designed to detect and locate lesions Recommendations for covariate-adjustment Methods for estimating and comparing predictive values andsample size calculations Correcting techniques for verification and imperfect standardbiases Sample size calculation for multiple reader studies when pilotdata are available Updated meta-analysis methods, now incorporating randomeffects Three case studies thoroughly showcase some of the questions andstatistical issues that arise in diagnostic medicine, with allassociated data provided in detailed appendices. A related web sitefeatures Fortran, SAS®, and R software packages so thatreaders can conduct their own analyses. Statistical Methods in Diagnostic Medicine, Second Edition is anexcellent supplement for biostatistics courses at the graduatelevel. It also serves as a valuable reference for clinicians andresearchers working in the fields of medicine, epidemiology, andbiostatistics.