Coxiella burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium PDF Download

Author: Rudolf Toman
Publisher: Springer Science & Business Media
ISBN: 9400743157
Category : Medical
Languages : en
Pages : 413

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Book Description
Coxiella burnetii is the etiological agent of Q fever, a zoonotic disease found worldwide. The bacterium is a fascinating example of intracellular parasitism that has uniquely evolved to thrive in the most inhospitable of cellular compartments-the phagolysosome. Understanding how C. burnetii resists the degradative functions of this vacuole, and the host cell functions coopted for successful parasitism, are central to understanding Q fever pathogenesis. Recent achievements in glycomics and proteomics are guiding development of enhanced detection schemes for the bacterium in addition to shedding light on the host immune response to the pathogen. Several chapters survey immune functions that control or potentially exacerbate Coxiella infection and delve into correlates of protective immunity elicited by vaccination. Comparative genomics is also the foundation of chapters discussing diagnostic antigen discovery and molecular typing of the bacterium, with significance for development of new clinical, epidemiologic, and forensic tools.

Author: E. Mitscherlich
Publisher: Springer Science & Business Media
ISBN: 364269974X
Category : Science
Languages : en
Pages : 807

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Book Description
This book is a collection of data on the tenacity in the environment of bacteria and some rickettsiae important in medicine and veterinary medicine. These data are of fundamental importance to physicians, veterinarians, epidemiologists and others when, in their practices, they are confronted with epidemics of contagious diseases or outbreaks of foodborne illnesses. At such times prompt answers are often needed to limit the problem, and thus to protect the public's health. Since data needed for such a purpose are widely distributed in the internatio nal scientific literature, the occasional desperate literature search is likely to miss some of the information that is available. This book seeks to fill that void. It lies in the nature of a compilation such as this is that it can never be totally complete. The compilation requires continual up-dating to include new information, and some currently acceptable information may have to be corrected as new data become available. However, most of the information in this compilation will never be out-of-date. The authors are always thankful for suggestions from others. Collection of the data in this book resulted from, first, several decades of studying the literature, and, second, literature searches made by the Institut fUr Dokumentationswesen in Frankfurt a. M. , the Biomedi zinische Datenbank of Hoechst A. G.

Author: Didier Raoult
Publisher: CRC Press
ISBN: 142001997X
Category : Medical
Languages : en
Pages : 400

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Book Description
The only available reference to comprehensively discuss the common and unusual types of rickettsiosis in over twenty years, this book will offer the reader a full review on the bacteriology, transmission, and pathophysiology of these conditions. Written from experts in the field from Europe, USA, Africa, and Asia, specialists analyze specific patho

Author: Dongyou Liu
Publisher: CRC Press
ISBN: 1466553987
Category : Medical
Languages : en
Pages : 884

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Book Description
Security sensitive microbes (viruses, bacteria, fungi, and parasites) and toxins, which are often referred to as the select agents and toxins, have the capacity to cause serious illness and death in humans, animals, and plants. Throughout history, these microbes and toxins have been exploited in one form or another as biowarfare and bioterror agents that create fear and panic well beyond any actual physical damages they might cause. Manual of Security Sensitive Microbes and Toxins provides comprehensive, state-of-the-art coverage of microbes and toxins of biosecurity concern. The ultimate goal is to increase our awareness of these agents and enhance our preparedness against any future bio-emergencies. The book begins with an introduction containing a brief overview of the historical aspects of security sensitive microbes and toxins. This is followed by a concise summary of the current status in relation to the regulation of security sensitive microbes and toxins and a discussion of future development trends. The book is divided into seven parts: Microbes and Toxins Affecting Humans and Animals: Viruses Microbes and Toxins Affecting Human and Animals: Bacteria Microbes and Toxins Affecting Human and Animals: Fungus and Parasite Microbes and Toxins Affecting Human and Animals: Toxins Microbes Affecting Animals: Viruses Microbes Affecting Animals: Bacteria Microbes Affecting Plants Written by experts in the relevant areas of research, the chapters are authoritative reviews, each one covering a single microbe or toxin with respect to its classification, biology, epidemiology, pathogenesis, identification, diagnosis, treatment, and prevention. The chapters also discuss the limitations of our current knowledge and challenges relating to improved detection and control of the microbe or toxin.

Author: Jim C. Williams
Publisher: CRC Press
ISBN: 9780849359835
Category : Medical
Languages : en
Pages : 384

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Book Description
Q fever is a zoonotic infectious disease caused by Coxiella burnetii, which infects a broad range of hosts. This volume presents critical reviews of the biological aspects of C. burnetii. Topics covered include C. burnetii's place in the microbial world through a comparison with other microorganisms that are phylogenetically related or share phenotypic traits; intrinsic properties of Coxiella with respect to infectivity, virulence, and pathogenecity; past and current methods for the isolation, amplification, and purification of C. Burnetii; obligate acidophily; metabolic capabilities, with emphasis on intermediary metabolism, macromolecular synthesis, and protein export; and human immune responses to bacterial components during acute and chronic infection by C. Burnetii. Other fascinating topics about C. Burnetii include antigens, virulence factors, and biological response modifiers; ultrastructure; genetics; cloning and expression; and C. burnetii in the U.S.S.R. and China. Epidemiologists, molecular biologists, microbiologists, and other researchers interested in Q fever and C. burnetii should consider this book an essential reference resource.

Author: Jasbir Singh Bedi
Publisher: John Wiley & Sons
ISBN: 1119809533
Category : Medical
Languages : en
Pages : 524

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Book Description
Textbook of Zoonoses Comprehensive resource covering the aetiology, epidemiology and transmission cycle, clinical symptoms, diagnosis, and prevention and control strategies of the important zoonoses. Zoonoses are the diseases which can spread from animals to humans. This book covers all important zoonoses that are prevalent in today’s world. As a modern learning resource, it incorporates recent scientific developments and concepts to give readers a complete overview of each zoonoses. Written by three well-qualified authors in academia, sample topics covered within the book include: Bacterial, viral, parasitic, rickettsial, fungal, prion, and foodborne zoonoses Aetiology and epidemiology of each zoonotic disease Clinical symptoms and diagnosis in animals and humans Treatment options, plus prevention and control strategies CDC classification of zoonotic agents and the WHO’s list of ‘neglected zoonoses’ Written for undergraduate and postgraduate students studying veterinary public health and epidemiology, Textbook of Zoonoses is also a helpful resource for other veterinary and medical professionals interested in public health and epidemiology.

Author: Yasobant, Sandul
Publisher: IGI Global
ISBN: 1522563059
Category : Medical
Languages : en
Pages : 306

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Book Description
Many factors have changed interactions between people, animals, and our environment including the emergence and reemergence of diseases such as swine flu, rabies, and diphtheria. By practicing the concept of one health, which relates the close interactions between people, animals, and our environment to overall health, a solution for global wellbeing can be found. Global Applications of One Health Practice and Care provides in-depth research on the concept of one health and the ability to achieve universal health by connecting human health with animal health and a safe environment. Featuring coverage on a broad range of topics such as holism health, drug resistance, and parasitic zoonoses, this book is ideally designed for policy planners, program managers, public health practitioners, animal health specialists, environmentalists, researchers, and academicians seeking current research on achieving better public health outcomes.

Author: Muhammad Abubakar
Publisher: BoD – Books on Demand
ISBN: 1789857651
Category : Medical
Languages : en
Pages : 184

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Book Description
It is vital to understand ticks and tick-borne pathogens as well as their impact on humans. This book is intended for students in parasitology, biologists, parasitologists involved in molecular diagnostics of tick-borne diseases, practicing veterinarians, and for others who may require information on ticks and tick-borne diseases. Here we have put together a collection of chapters focused on different aspects of ticks and tick-borne diseases mainly to provide the reader with novel information in the field, but not the basic generalised information provided by many textbooks. This book includes topics such as high-throughput technologies in diagnosis, discovery of novel tick vaccines, identification of new pathogens transmitted by ticks, and new epidemiological information of certain well-known ticks and tick-borne diseases. These chapters were authored by parasitologists from all over the world, giving an insight to the reader about significant ticks and tick-borne diseases prevalent in those particular geographical regions with the local expert's point of view. Each of the chapters has separate reference lists, making it easier for the reader to find additional reading material related to their topic of interest.

Author: Manal Mohammad Baddour
Publisher: BoD – Books on Demand
ISBN: 9535122118
Category : Medical
Languages : en
Pages : 258

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Book Description
Brucellosis is a major zoonotic disease that may cause a serious illness in humans and animals. Global prevalence of human brucellosis remains significant. More than half a million new brucellosis cases from 100 countries are reported annually to the World Health Organization (WHO). The majority of these cases are reported in developing countries.In humans, brucellosis (undulant fever, Malta fever) is characterized by an acute bacteremic phase followed by a chronic stage that may extend over many years and may involve many tissues. It is a systemic disease, and many organ systems (nervous system, heart, skeletal system, bone marrow, etc.) may become involved following hematogenous dissemination. Although eradicated in some countries, it remains one of the most economically important zoonosis worldwide as it is responsible for huge economic losses as well as significant human morbidity in endemic areas. Because of the nonspecific clinical manifestations of human brucellosis and the need for prolonged combination therapy with antibiotics that are not routinely prescribed for other infectious diseases, laboratory confirmation of the diagnosis is of paramount importance for adequate patient management. In addition, evidence of brucellosis has serious public health implications because it discloses exposure to a contaminated source (infected animals or their products, unsafe laboratory practices, or a potential biological warfare attack). This book addresses human brucellosis with stress on symptoms including those related to the less recognized disease localizations, risk of exposure, treatment, and prevention. Light is shed on animal brucellosis as it pertains to human exposure. The book also emphasizes on laboratory procedures in culturing and serologic techniques. Epidemiologic surveillance is among this books subjects as well as veterinary control measures.

Author:
Publisher: John Wiley & Sons
ISBN: 1555818811
Category : Medical
Languages : en
Pages : 2954

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Book Description
In response to the ever-changing needs and responsibilities of the clinical microbiology field, Clinical Microbiology Procedures Handbook, Fourth Edition has been extensively reviewed and updated to present the most prominent procedures in use today. The Clinical Microbiology Procedures Handbook provides step-by-step protocols and descriptions that allow clinical microbiologists and laboratory staff personnel to confidently and accurately perform all analyses, including appropriate quality control recommendations, from the receipt of the specimen through processing, testing, interpretation, presentation of the final report, and subsequent consultation.