OECD Conceptual Framework for Testing and Assessment of Endocrine Disrupters as a basis for regulation of substances with endocrine disrupting properties PDF Download

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OECD Conceptual Framework for Testing and Assessment of Endocrine Disrupters as a basis for regulation of substances with endocrine disrupting properties

OECD Conceptual Framework for Testing and Assessment of Endocrine Disrupters as a basis for regulation of substances with endocrine disrupting properties PDF Author: Ulla Hass
Publisher: Nordic Council of Ministers
ISBN: 9289310731
Category : Medical
Languages : en
Pages : 101

Book Description
The existing EU chemical legislation only covers some of the effects caused by endocrine disruption. In the proposal for the new REACH system, endocrine disrupters are covered by the authorisation procedure based on a case-by-case assessment, but no indication of criteria for the assessment is given. Several toxicological and ecotoxicological screening tests for predicting endocrine disrupting properties of a chemical are now under development and international validation within the OECD, but it will probably take several years before the full range of validated testing methods and criteria are developed. In the meantime there is a need for guidance on how to interpret test results from existing test methods and how to identify a substance as an endocrine disrupter. Regulatory instruments that can be used towards endocrine disrupters should also be considered in this interim period. The aim of this project has been to investigate if and how the OECD Conceptual Framework for Testing and Assessment of Endocrine Disrupters can be used as a basis for regulatory initiatives towards endocrine disrupters. The report includes an assessment of the tests in the OECD Conceptual Framework, including specification of the endpoint for the test and reliability and relevance for effects in humans. This report is expected to serve as a basis for the Nordic contribution to the discussions in EU on interpretation and use of test results indicating endocrine disruption for regulatory purposes and furthermore, how to integrate endocrine disrupters in the new EU chemicals regulation.

OECD Conceptual Framework for Testing and Assessment of Endocrine Disrupters as a basis for regulation of substances with endocrine disrupting properties

OECD Conceptual Framework for Testing and Assessment of Endocrine Disrupters as a basis for regulation of substances with endocrine disrupting properties PDF Author: Ulla Hass
Publisher: Nordic Council of Ministers
ISBN: 9289310731
Category : Medical
Languages : en
Pages : 101

Book Description
The existing EU chemical legislation only covers some of the effects caused by endocrine disruption. In the proposal for the new REACH system, endocrine disrupters are covered by the authorisation procedure based on a case-by-case assessment, but no indication of criteria for the assessment is given. Several toxicological and ecotoxicological screening tests for predicting endocrine disrupting properties of a chemical are now under development and international validation within the OECD, but it will probably take several years before the full range of validated testing methods and criteria are developed. In the meantime there is a need for guidance on how to interpret test results from existing test methods and how to identify a substance as an endocrine disrupter. Regulatory instruments that can be used towards endocrine disrupters should also be considered in this interim period. The aim of this project has been to investigate if and how the OECD Conceptual Framework for Testing and Assessment of Endocrine Disrupters can be used as a basis for regulatory initiatives towards endocrine disrupters. The report includes an assessment of the tests in the OECD Conceptual Framework, including specification of the endpoint for the test and reliability and relevance for effects in humans. This report is expected to serve as a basis for the Nordic contribution to the discussions in EU on interpretation and use of test results indicating endocrine disruption for regulatory purposes and furthermore, how to integrate endocrine disrupters in the new EU chemicals regulation.

Fertili-Plus Conception Framework

Fertili-Plus Conception Framework PDF Author:
Publisher: ANF INNOVATIONS
ISBN:
Category :
Languages : en
Pages : 36

Book Description


New Reproductive Technologies

New Reproductive Technologies PDF Author: Maureen McNeil
Publisher: Springer
ISBN: 1349205486
Category : Social Science
Languages : en
Pages : 270

Book Description
This collection of essays provides an overview of the social developments associated with the new reproductive technologies. It assesses the significance of these new technologies for the field of the sociology of technology as a whole.

War, Humanitarian Crises, Population Displacement, and Fertility

War, Humanitarian Crises, Population Displacement, and Fertility PDF Author: Program on Forced Migration and Health at the Mailman School of Public Health, Columbia University
Publisher: National Academies Press
ISBN: 0309165997
Category : Social Science
Languages : en
Pages : 46

Book Description
Fertility and reproductive health issues more broadly have tended to be of low priority in humanitarian crises. Public attention is drawn by information concerning the magnitude of refugee flows, of death tolls, and of numbers of injuries. Reproductive health has been regarded as a longer term issue that could safely be put on the back burner during the crisis phase of an emergency, when issues of providing adequate food, clean water, and shelter, plus treating acute infectious diseases of crowding, take priority. This report reviews what evidence there is concerning the effects of humanitarian crisis on fertility, with a view to identifying common patterns that may exist across settings and be of value in guiding responses to future crises.

Soil and Soil Fertility Management Research in Sub-Saharan Africa

Soil and Soil Fertility Management Research in Sub-Saharan Africa PDF Author: Henk Mutsaers
Publisher: Routledge
ISBN: 131551883X
Category : Technology & Engineering
Languages : en
Pages : 390

Book Description
Judicious soil fertility management is crucial for sustainable crop production and food security in sub-Saharan Africa (SSA). This book describes the various concepts and approaches underlying soil and soil fertility management research in SSA over the last fifty years. It provides examples of important innovations generated and assesses the position of research within the research-to-development continuum, including how innovations have been validated with the intended beneficiaries. Using the experience of the International Institute of Tropical Agriculture (IITA) as a case study, the authors analyse how processes, partnerships and other factors have affected research priorities, the delivery of outputs, and their uptake by farming communities in SSA. They evaluate both successes and failures of past investments in soil fertility research and important lessons learnt which provide crucial information for national and international scientists currently engaged in this research area. The book is organised in a number of chapters each covering a chronological period characterised by its primary research content and approaches and by the dominant research paradigms and delivery models.

Disease Control Priorities, Third Edition (Volume 2)

Disease Control Priorities, Third Edition (Volume 2) PDF Author: Robert Black
Publisher: World Bank Publications
ISBN: 1464803684
Category : Medical
Languages : en
Pages : 416

Book Description
The evaluation of reproductive, maternal, newborn, and child health (RMNCH) by the Disease Control Priorities, Third Edition (DCP3) focuses on maternal conditions, childhood illness, and malnutrition. Specifically, the chapters address acute illness and undernutrition in children, principally under age 5. It also covers maternal mortality, morbidity, stillbirth, and influences to pregnancy and pre-pregnancy. Volume 3 focuses on developments since the publication of DCP2 and will also include the transition to older childhood, in particular, the overlap and commonality with the child development volume. The DCP3 evaluation of these conditions produced three key findings: 1. There is significant difficulty in measuring the burden of key conditions such as unintended pregnancy, unsafe abortion, nonsexually transmitted infections, infertility, and violence against women. 2. Investments in the continuum of care can have significant returns for improved and equitable access, health, poverty, and health systems. 3. There is a large difference in how RMNCH conditions affect different income groups; investments in RMNCH can lessen the disparity in terms of both health and financial risk.

Reproductive Agency, Medicine and the State

Reproductive Agency, Medicine and the State PDF Author: Maya Unnithan-Kumar
Publisher: Berghahn Books
ISBN: 9781845450441
Category : Health & Fitness
Languages : en
Pages : 272

Book Description
Recent years have seen many changes in human reproduction resulting from state and medical interventions in childbearing processes. Based on empirical work in a variety of societies and countries, this volume considers the relationship between reproductive processes (of fertility, pregnancy, childbirth and the postpartum period) on the one hand and attitudes, medical technologies and state health policies in diverse cultural contexts on the other. Maya Unnithan-Kumar is Senior Lecturer in Anthropology at the University of Sussex. Her research in the early 1990s focused on kinship and gender relations in northwest India and appeared as Identity, Gender and Poverty (Berghahn Books 1997).

Six Billion Plus

Six Billion Plus PDF Author: K. Bruce Newbold
Publisher: Rowman & Littlefield
ISBN: 9780742539297
Category : Medical
Languages : en
Pages : 264

Book Description
Recognizing that world population growth will be explosive well into the twenty-first century, Six Billion Plus offers a geographical and global perspective on the profound implications of this trend. This compact, balanced, and accessible text focuses on the key factors that will shape the global environment in the decades to come, including population fertility, epidemics like HIV/AIDS, legal and illegal immigration, refugee flows, scarce resources, and the potential for conflict. This fully updated edition will be an invaluable resource for all readers concerned with the intertwined issues of population, environment, and health.

Genetic Influences on Human Fertility and Sexuality

Genetic Influences on Human Fertility and Sexuality PDF Author: Joseph Lee Rodgers
Publisher: Springer Science & Business Media
ISBN: 146154467X
Category : Medical
Languages : en
Pages : 335

Book Description
Recent work in quantitative biology has shown theoretically why Fisher's Fundamental Theorem of Natural Selection does not preclude genetic influences on fertility, sexuality, and related processes. Genetic Influences on Human Fertility and Sexuality takes the next step, and presents a number of successful empirical searches for such genetic influence on a broad range of processes, such as puberty, marriage, sexual behavior, and twinning. Employing a broad range of methodological approaches, including molecular and behavioral genetics, this book weaves a new theoretical framework that shows how genes can help relate fertility planning to fertility outcome, and how puberty, sexuality, marriage, and reproduction can be conceptually linked through the genes that contribute to individual differences in the human process.

Education and Postponement of Maternity

Education and Postponement of Maternity PDF Author: Siv Gustafsson
Publisher: Springer Science & Business Media
ISBN: 1402047169
Category : Social Science
Languages : en
Pages : 336

Book Description
This book examines economic aspects of the role of women’s education in the postponement of maternity in ten industrialized countries or regions: Sweden, Norway, Italy, Spain, Ireland, the Netherlands and Western Germany, the Czech Republic and Eastern Germany, and the United States. Each is investigated using survey data relating age at motherhood with the investment in education of the mother. The result is a detailed picture of the economics of fertility decisions.