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Immunodiagnostic Technologies from Laboratory to Point-Of-Care Testing

Immunodiagnostic Technologies from Laboratory to Point-Of-Care Testing PDF Author: Pankaj Suman
Publisher: Springer Nature
ISBN: 981155823X
Category : Medical
Languages : en
Pages : 245

Book Description
This book presents the timeline of immunodiagnostics evolution, including advancements in immunological/nucleic acid probes, assay design, labelling techniques, and devices for signal transduction and acquisition. In the past few years, enzyme and nanocatalyst-based immune assays have undergone numerous modifications to enhance their sensitivity and potential for automation. Further, to reduce production costs and the use of laboratory animals, engineering small antibodies and nucleic acid probes (aptamers) has become increasingly popular in the development of novel and powerful bioassays. In light of the notable advancements in immunodiagnostics, this book highlights the combined efforts of clinicians, biotechnologists, material scientists, nanotechnologists and basic scientists in a coherent and highly structured way. The book takes readers on the journey of immunodiagnostic technologies, from their introduction to the present.

Immunodiagnostic Technologies from Laboratory to Point-Of-Care Testing

Immunodiagnostic Technologies from Laboratory to Point-Of-Care Testing PDF Author: Pankaj Suman
Publisher: Springer Nature
ISBN: 981155823X
Category : Medical
Languages : en
Pages : 245

Book Description
This book presents the timeline of immunodiagnostics evolution, including advancements in immunological/nucleic acid probes, assay design, labelling techniques, and devices for signal transduction and acquisition. In the past few years, enzyme and nanocatalyst-based immune assays have undergone numerous modifications to enhance their sensitivity and potential for automation. Further, to reduce production costs and the use of laboratory animals, engineering small antibodies and nucleic acid probes (aptamers) has become increasingly popular in the development of novel and powerful bioassays. In light of the notable advancements in immunodiagnostics, this book highlights the combined efforts of clinicians, biotechnologists, material scientists, nanotechnologists and basic scientists in a coherent and highly structured way. The book takes readers on the journey of immunodiagnostic technologies, from their introduction to the present.

Point-of-care testing

Point-of-care testing PDF Author: Peter Luppa
Publisher: Springer
ISBN: 3662544970
Category : Medical
Languages : en
Pages : 445

Book Description
The underlying technology and the range of test parameters available are evolving rapidly. The primary advantage of POCT is the convenience of performing the test close to the patient and the speed at which test results can be obtained, compared to sending a sample to a laboratory and waiting for results to be returned. Thus, a series of clinical applications are possible that can shorten the time for clinical decision-making about additional testing or therapy, as delays are no longer caused by preparation of clinical samples, transport, and central laboratory analysis. Tests in a POC format can now be found for many medical disciplines including endocrinology/diabetes, cardiology, nephrology, critical care, fertility, hematology/coagulation, infectious disease and microbiology, and general health screening. Point-of-care testing (POCT) enables health care personnel to perform clinical laboratory testing near the patient. The idea of conventional and POCT laboratory services presiding within a hospital seems contradictory; yet, they are, in fact, complementary: together POCT and central laboratory are important for the optimal functioning of diagnostic processes. They complement each other, provided that a dedicated POCT coordination integrates the quality assurance of POCT into the overall quality management system of the central laboratory. The motivation of the third edition of the POCT book from Luppa/Junker, which is now also available in English, is to explore and describe clinically relevant analytical techniques, organizational concepts for application and future perspectives of POCT. From descriptions of the opportunities that POCT can provide to the limitations that clinician’s must be cautioned about, this book provides an overview of the many aspects that challenge those who choose to implement POCT. Technologies, clinical applications, networking issues and quality regulations are described as well as a survey of future technologies that are on the future horizon. The editors have spent considerable efforts to update the book in general and to highlight the latest developments, e.g., novel POCT applications of nucleic acid testing for the rapid identification of infectious agents. Of particular note is also that a cross-country comparison of POCT quality rules is being described by a team of international experts in this field.

Surface Engineering and Functional Nanomaterials for Point-of-Care Analytical Devices

Surface Engineering and Functional Nanomaterials for Point-of-Care Analytical Devices PDF Author: Buddhadev Purohit
Publisher: Springer Nature
ISBN: 9819930251
Category : Science
Languages : en
Pages : 350

Book Description
This book chronicles the role of advanced nanomaterials and surface engineering technologies in the development of point-of-care biosensors for health and environmental monitoring. All aspects of nanomaterial synthesis and characterization, functionalization methods, sensing surface engineering, signal amplification strategies, use of innovative technologies to enhance sensor efficiency and performances, and innovative applications of nanobiosensors to tackle real-life problems are discussed in this book with a focus on optical and electrochemical based sensing. It also covers the detection of infectious diseases and various disease biomarkers, smartphone-based biosensing, and portable diagnostics module developments with a discussion on the working mechanisms of these devices in various domains. The book also illustrates the recent trends in biosensing, and an overview of the challenges and probable solutions for the translation of biosensors from laboratory prototypes to commercial success. ​

BioSensing, Theranostics, and Medical Devices

BioSensing, Theranostics, and Medical Devices PDF Author: Vivek Borse
Publisher: Springer Nature
ISBN: 9811627827
Category : Medical
Languages : en
Pages : 380

Book Description
This book provides up-to-date information on the prototypes used to develop medical devices and explains the principles of biosensing and theranostics. It also discusses the development of biosensor and application-orientated design of medical devices. In addition to summarizing the clinical validation of the developed techniques and devices and the regulatory steps involved in their commercialization, the book highlights the latest research and translational technologies toward the development of point-of-care devices in the health care. Lastly, it explores the current opportunities, challenges and provides troubleshooting on the use of biosensors in precision medicine. The book is helpful for researchers and medical professionals working in the field of clinical theranostics, and medical-device development wanting to gain a better understanding into the principles and processes involved in the development of biosensors.

Sustainable Agriculture Reviews 54

Sustainable Agriculture Reviews 54 PDF Author: Vinod Kumar Yata
Publisher: Springer Nature
ISBN: 3030765296
Category : Technology & Engineering
Languages : en
Pages : 288

Book Description
This book reviews concepts and recent advances of biotechnological approaches for livestock production. Indeed, biotechnologies have recently emerged as powerful tools for animal breeding, genetics, production, nutrition, and animal health. Applications to the production of livestock such as cattle, camel, and poultry are detailed. Chapters also present biotechnological applications for diagnostics, animal nutrition, and animal food production.

Miniaturized Biosensing Devices

Miniaturized Biosensing Devices PDF Author: Pranjal Chandra
Publisher: Springer Nature
ISBN: 981169897X
Category : Science
Languages : en
Pages : 371

Book Description
This book presents tools and techniques for the development of miniature biosensors and their applications. The initial chapters discuss the advancements in the development of the transduction techniques, including optical, electrochemical, and piezoelectric, which are used for miniaturized biosensors. The book also reviews several technologies, such as nanotechnology, nanobiotechnology, immune-technology, DNA-technology, micro-manufacturing technology, electronic-circuit technology to increase the miniaturization and sensitivity of the biosensor platform. Subsequently, the chapters illustrate the applications of miniaturized biosensing systems in point-of-care monitoring of treatment and disease progression, environmental monitoring, food control, drug discovery, forensics, and biomedical research. Towards the end, the book discusses the advanced applications of biosensors in water quality monitoring, especially on-line detection systems and on-site detection of pesticides, heavy metals and bacteria in water. This book is an invaluable source for scientists working in biochemical engineering, bioengineering, and biomedical engineering in academia and industry.

Clinical Immunodiagnostics: Laboratory Principles and Practices

Clinical Immunodiagnostics: Laboratory Principles and Practices PDF Author: Ian C. Clift
Publisher: Jones & Bartlett Learning
ISBN: 1284219259
Category : Medical
Languages : en
Pages : 770

Book Description
A contemporary guide to the diagnostic principles and practices of immunology and serology in the clinical laboratory.

Proof and Concepts in Rapid Diagnostic Tests and Technologies

Proof and Concepts in Rapid Diagnostic Tests and Technologies PDF Author: Shailendra K. Saxena
Publisher: BoD – Books on Demand
ISBN: 953512580X
Category : Medical
Languages : en
Pages : 174

Book Description
This book gives a comprehensive overview of the recent advancements and developments of rapid diagnostic tests (RDTs) and technologies, which are quite novel approaches and might be used as laboratory bench manual for the rapid diagnosis of the various disease conditions. The book focuses on various aspects and properties of RDTs, point-of-care tests (POCTs), quality control, assurance, calibration, safety, nano-/microfluidic technologies, and fusion with DNA technologies. I hope that this work might increase the interest in this field of research and that the readers will find it useful for their investigations, management, and clinical usage.

Nanosensing and Bioanalytical Technologies in Food Quality Control

Nanosensing and Bioanalytical Technologies in Food Quality Control PDF Author: Pranjal Chandra
Publisher: Springer Nature
ISBN: 9811670293
Category : Technology & Engineering
Languages : en
Pages : 447

Book Description
This book reviews applications of nanomaterial and nanodevices in the food industry. It also discusses the advanced bioanalytical techniques, including Enzyme-Linked Immunosorbent Assay (ELISA), immunoanalytical techniques, monoclonal antibody-based immunological techniques for detecting food adulterations and allergens. It comprehensively covers electrode modification and nano-engineered fabrication of biosensors to enhance their functionalities for utilization in food industries. The book highlights the utilization of nanobiosensors for food safety and quality analysis, such as detection of toxin, food-borne pathogen, allergen, and evaluation of toxicity. Further, it also summarizes the recent advances in nanodevices such as nano-systems, nano-emulsions, nanopesticide, nanocapsule and their applications in the food industry. Lastly, it covers nanomaterial-based sensors for drug analysis in diverse matrices. It serves as an invaluable source of information for professionals, researchers, academicians, and students related to food science and technology.

The Coronavirus Pandemic and the Future

The Coronavirus Pandemic and the Future PDF Author: Michael D Waters
Publisher: Royal Society of Chemistry
ISBN: 1839166843
Category : Medical
Languages : en
Pages : 695

Book Description
This second volume chronicles the later stages of the outbreak of SARS-Cov-2 (COVID-19) and delineates the role of several disciplines in therapeutic and control measures highliting the response from specific coutries of note and efforts to repurpose and produce new therapeutics and vaccines. By addressing considerations of efficacy and safety of drugs and chemicals used to combat COVID-19, virtually in real-time, this book documents and highlights the advances in science and place the toxicology, pharmaceutical science, public health and medical community in a better position to advise in future epidemics.