Magnetic Resonance Spectroscopy Diagnosis of Neurological Diseases PDF Download

Author: Else Rubaek Danielsen
Publisher: CRC Press
ISBN: 1482270102
Category : Medical
Languages : en
Pages : 344

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Book Description
Demonstrates how MRS offers a useful tool for the noninvasive biochemical analysis of the brain. The book covers over 70 clinical cases and more than 100 spectra that enhance skills at interpreting MRS, including minimizing errors, highlighting artifacts, and expanding the clinical usefulness of this diagnostic modality.

Author: Lara Alexandre Brandão
Publisher: Lippincott Williams & Wilkins
ISBN: 0781746167
Category : Medical
Languages : en
Pages : 426

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Book Description
This volume is a practical guide to the technique and most frequent clinical applications of magnetic resonance spectroscopy (MRS) of the brain. Using more than 500 images, the authors present the fundamentals of MRS in a straightforward fashion and show radiologists and neurologists how to recognize normal and disease processes on scans. The book presents the spectra of the most common neurological disease entities, along with the conventional images and perfusion and diffusion where appropriate. The authors thoroughly describe the pathology and key MRS features of each disease process. Each chapter ends with a quick-reference summary of the main findings.

Author: M. Filippi
Publisher: Springer Science & Business Media
ISBN: 884702109X
Category : Medical
Languages : en
Pages : 153

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Book Description
Recent years have witnessed dramatic advances in the development and use of magnetic resonance imaging (MRI) techniques that can provide quantitative measures with some degree of pathological specificity for the heterogeneous substrates of multiple sclerosis (MS). Magnetic resonance spectroscopy (MRS) is one of the most promising of these techniques. Thanks to MRS, axonal damage is no longer considered an end-stage phenomenon typical of only the most destructive lesions and the most unfortunate cases, but rather as a major component of the MS pathology of lesions and normal-appearing white matter at all the phases of the disease. This new concept is rapidly changing our understanding of MS pathophysiology and, as a consequence, the therapeutic strategies to modify the disease course favorably. Many of the authors have pionereed the use of MRS in MS, thus contributing to the foundation of the "axonal hypothesis".

Author: Peter B. Barker
Publisher: Cambridge University Press
ISBN: 052186898X
Category : Medical
Languages : en
Pages : 275

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Book Description
Covers all MR spectroscopy techniques and their clinical applications in neurological disorders, malignancies and musculoskeletal diseases.

Author: Akihiro Igata
Publisher: CRC Press
ISBN: 1482273942
Category : Medical
Languages : en
Pages : 352

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Book Description
MRS of the Brain and Neurological Disorders illustrates and demonstrates the usefulness of magnetic resonance spectroscopy for the diagnosis of brain and neurological disorders, including epilepsy, nervous disorders, psychiatric disorders, and brain tumors. The book is unique in that it contains 87 case studies of neurologic and psychiatric diso

Author: Rakesh K. Gupta
Publisher: Springer Science & Business Media
ISBN: 0306468441
Category : Medical
Languages : en
Pages : 356

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Book Description
Central nervous system (CNS) infections continue to pose a serious problem in health care even with improved knowledge and treatment. Despite the introduction of newer antimicrobial agents and diagnostic techniques, the morbidity and mortality associated with CNS infections remain high. The morbidity associated with CNS infections may be even more important than the death rate especially in developing countries as neurological sequelae may deprive the survivors of intellect and physical ability, demeaning the quality of life and burdening health resources and social services. MR imaging is an important integral part of the protocol for the management of CNS infections and MR spectroscopy is increasingly being utilized in its management. This work is an attempt to provide a comprehensive review of imaging and spectroscopy of the commonly encountered CNS infections in the clinical practice in developing and developed countries. The first chapter deals with basic physical principles of MR imaging and spectroscopy that will help beginners to understand the technical terms used in subsequent chapters. The remaining 10 chapters deal with clinical, pathological, MR imaging and spectroscopy features and their applications in CNS infections. This will help in giving a comprehensive understanding to readers with a background in clinical, radiological, basic MRI, and neurological sciences. The T2 hypointense lesions are a real diagnostic dilemma especially in developing countries for which an algorithm has been suggested in the concluding chapter.

Author: Lara A. Brandao
Publisher: Elsevier Health Sciences
ISBN: 0323186297
Category : Medical
Languages : en
Pages : 220

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Book Description
This issue focuses on MR Spectroscopy (MRS) for neuroimaging. Topics include MRS for Common Dementias, Epilepsy, Metabolic Disorders, Hypoxic-isquemic Injuries, Multiple Sclerosis, Brain Infections, Pediatric Brain Tumors, Adult Brain Neoplasms.

Author: Gülin Öz
Publisher: Springer
ISBN: 3319335553
Category : Medical
Languages : en
Pages : 279

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Book Description
The proposed book will act as a guide for scientists and clinicians to the unique information that MRS can provide. It will be a comprehensive overview of clinical and pre-clinical MRS applications and potential clinical utility of MRS biomarkers in degenerative brain diseases from leading experts in the field. MRS has proven to be a powerful complementary tool to MRI for the diagnosis and monitoring of disease progression and response to treatment because it can detect changes in cell density, cell type, and biochemical composition, not just structural changes. As the population in the developed world continues to age, neuroimaging for diagnosis, prognosis, and therapy monitoring of neurodegenerative diseases becomes increasingly important and there has been a recent surge of clinical and pre-clinical applications of MRS indicating that this technique can provide robust and non-invasive biomarkers of degeneration. ​

Author: Stefan Blüml
Publisher: Springer Science & Business Media
ISBN: 1441958649
Category : Medical
Languages : en
Pages : 405

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Book Description
Magnetic resonance spectroscopy (MRS) is a modality available on most clinical MR scanners and readily integrated with standard MR imaging (MRI). For the brain in particular, MRS has been a powerful research tool providing additional clinically relevant information for several disease families such as brain tumors, metabolic disorders, and systemic diseases. The most widely-available MRS method, proton (1H; hydrogen) spectroscopy, is FDA approved for general use in the US and can be ordered by clinicians for patient studies if indicated. There are several books available that describe applications of MRS in adults. However, to the best of our knowledge there is currently no book available that focuses exclusively on applications in pediatrics. MR spectroscopy in the pediatric population is different from adults for two main reasons. Particularly in the newborn phase the brain undergoes biochemical maturation with dramatic changes of the "normal" biochemical fingerprint. Secondly, brain diseases in the pediatric population are different from adult disorders. For example, brain tumors, which are mostly gliomas in the adults, often originate from different cell types and are also more diverse even within the same type and grade of tumor. This diversity of diseases and its implications for MR spectroscopy has not been addressed sufficiently in the literature, we believe. The target audience for "MR Spectroscopy of Pediatric Brain Disorders" are thus both clinicians and researchers involved with pediatric brain disorders. This includes radiologists, neurologists, neurooncologists, neurosurgeons, and more broadly the neuroscience and neurobiology community. This book will provide the necessary background information to understand the basics of MR spectroscopy. This will be followed by a detailed discussion of the normal biochemical maturation which will highlight the metabolic differences between the pediatric and adult brain. Thereafter, in SECTION I individual chapters will address various pediatric brain disease families. Of particular importance for pediatrics are case studies. For that reason, SECTION II will contain a large number of case studies. This will be particularly important for clinicians who may want to see examples of MRS for various conditions. A standardized format will be used for case reports that allow the reader to quickly understand the history of each case presented and the significance of the findings. The case reports will also include information from other imaging modalities to point out any added value of MRS in addition to conventional studies and clinical information. This section is necessary because the format of providing more complete information about individual patients is not practical for the chapters in SECTION I.

Author: Herman Bachelard
Publisher: Springer Science & Business Media
ISBN: 1461558638
Category : Medical
Languages : en
Pages : 427

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Book Description
The Advances in Neurochemistry series was initiated for a readership of neuroscientists with a background in biochemistry. True to this concept, the present volume brings together various applications of magnetic resonance technology to advance our knowledge of how the nervous system functions. Whether at the cellular, tissue slice, or intact organism level. magnetic resonance techniques are by their nature noninvasive, and thus provide a window through which biochemical reactions can be viewed without grinding, binding, or other wise perturbing ongoing physiological processes. As technological improve ments in methodology, such as higher and more uniform magnetic fields, novel paradigms for data analysis, etc. , are made, we find increased sensitivity and improved temporal and spatial resolution for functional imaging techniques on the one hand, and better separation of signals that identify chemical properties in spectral shift studies, on the other. It is upon knowledge such as is described in the twelve chapters that follow, that further advances in scientific discovery and the biomedical applications of tomorrow will be based. We are grateful to Dr. Bachelard, the Volume Editor, and to the authors of the individual chapters for their efforts. We also note that with this volume Dr. Morris Aprison, a co-founder of the Advances in Neurochemistry series has stepped down and acknowledge with thanks his major role in its inception. In addition, we thank our past and present Advisory Editors. Bernard W. Agranoff Kunihiko Suzuki Series Editors ix CONTENTS LIST OF SYMBOLS AND GLOSSARY . . . . . . . . . . . . . . . . . . . . . . . . . . . XXI INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .