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Modulating Gene Expression

Modulating Gene Expression PDF Author: Aditi Singh
Publisher: BoD – Books on Demand
ISBN: 1838806962
Category : Medical
Languages : en
Pages : 136

Book Description
RNA interference (RNAi) is a widely used technology for gene silencing and has become a key tool in a myriad of research and lead discoveries. In recent years, the mechanism of RNAi agents has been well investigated, and the technique has been optimized for better effectiveness and safety. On the other hand, the clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9/gRNA system is a recent, novel, targeted genome-editing technique derived from the bacterial immune system. Recent advances in gene-editing research and technologies have enabled the CRISPR Cas9 system to become a popular tool for sequence-specific gene editing to correct and modify eukaryotic systems. In this book, we will focus on the mechanisms, applications, regulations (their pros and cons), and various ways in which RNAi-based methods and CRIPSR-Cas9 technology have stimulated the modulation of gene expression, thereby making them a promising therapeutic tool to treat and prevent complex diseases and disorders.

Modulating Gene Expression

Modulating Gene Expression PDF Author: Aditi Singh
Publisher: BoD – Books on Demand
ISBN: 1838806962
Category : Medical
Languages : en
Pages : 136

Book Description
RNA interference (RNAi) is a widely used technology for gene silencing and has become a key tool in a myriad of research and lead discoveries. In recent years, the mechanism of RNAi agents has been well investigated, and the technique has been optimized for better effectiveness and safety. On the other hand, the clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9/gRNA system is a recent, novel, targeted genome-editing technique derived from the bacterial immune system. Recent advances in gene-editing research and technologies have enabled the CRISPR Cas9 system to become a popular tool for sequence-specific gene editing to correct and modify eukaryotic systems. In this book, we will focus on the mechanisms, applications, regulations (their pros and cons), and various ways in which RNAi-based methods and CRIPSR-Cas9 technology have stimulated the modulation of gene expression, thereby making them a promising therapeutic tool to treat and prevent complex diseases and disorders.

Modulating Gene Expression - Abridging the RNAi and CRISPR-Cas9 Technologies

Modulating Gene Expression - Abridging the RNAi and CRISPR-Cas9 Technologies PDF Author: Mohammad W. Khan
Publisher:
ISBN: 9781838806972
Category : Genetics
Languages : en
Pages : 134

Book Description
RNA interference (RNAi) is a widely used technology for gene silencing and has become a key tool in a myriad of research and lead discoveries. In recent years, the mechanism of RNAi agents has been well investigated, and the technique has been optimized for better effectiveness and safety. On the other hand, the clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9/gRNA system is a recent, novel, targeted genome-editing technique derived from the bacterial immune system. Recent advances in gene-editing research and technologies have enabled the CRISPR Cas9 system to become a popular tool for sequence-specific gene editing to correct and modify eukaryotic systems. In this book, we will focus on the mechanisms, applications, regulations (their pros and cons), and various ways in which RNAi-based methods and CRIPSR-Cas9 technology have stimulated the modulation of gene expression, thereby making them a promising therapeutic tool to treat and prevent complex diseases and disorders.

RNA Interference and CRISPR Technologies

RNA Interference and CRISPR Technologies PDF Author: Mouldy Sioud
Publisher: Humana
ISBN: 9781071602928
Category : Medical
Languages : en
Pages : 486

Book Description
This volume explores the uses of RNAi and CRISPR interferences as a general method for inhibiting gene expression, with focus on their biological functions, design, chemical modifications, delivery, and preclinical/clinical applications. In addition to relevant backgrounds, the chapters in this book discuss simple and accurate protocols dealing with the latest advances in RNAi and CRISPR applications and look at how these methods differ from one another. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, RNA Interference and CRISPR Technologies: Technical Advances and New Therapeutic Opportunities is a valuable resource for any scientist, teachers, graduate student, postdoc, and clinician interested in this field. This book also benefits anyone in research and development in biotech and pharmaceutical companies who want to understand more about these technologies, and their applications in biology and medicine.

Asian Citrus Psyllid

Asian Citrus Psyllid PDF Author: Jawwad A. Qureshi
Publisher: CABI
ISBN: 1786394081
Category : Science
Languages : en
Pages : 307

Book Description
This book, written by a team of experts on the Asian citrus psyllid, gathers together everything currently known about the biology and ecology of this important pest species, examines the transmission and acquisition processes of the pathogen, and looks at current management practices and their effectiveness. The potential for new, innovative management techniques are also described, along with the economic implications of managing this rapidly establishing disease.

Advances and Challenges of RNAi Based Technologies for Plants - Volume 2

Advances and Challenges of RNAi Based Technologies for Plants - Volume 2 PDF Author: Bruno Mezzetti
Publisher: Frontiers Media SA
ISBN: 2889767175
Category : Science
Languages : en
Pages : 168

Book Description


RNAi Based Pesticides

RNAi Based Pesticides PDF Author: Hailing Jin
Publisher: Frontiers Media SA
ISBN: 2889714020
Category : Science
Languages : en
Pages : 151

Book Description


Advances in Animal Genomics

Advances in Animal Genomics PDF Author: Sukanta Mondal
Publisher: Academic Press
ISBN: 0128206128
Category : Science
Languages : en
Pages : 340

Book Description
Advances in Animal Genomics provides an outstanding collection of integrated strategies involving traditional and modern - omics (structural, functional, comparative and epigenomics) approaches and genomics-assisted breeding methods which animal biotechnologists can utilize to dissect and decode the molecular and gene regulatory networks involved in the complex quantitative yield and stress tolerance traits in livestock. Written by international experts on animal genomics, this book explores the recent advances in high-throughput, next-generation whole genome and transcriptome sequencing, array-based genotyping, and modern bioinformatics approaches which have enabled to produce huge genomic and transcriptomic resources globally on a genome-wide scale. This book is an important resource for researchers, students, educators and professionals in agriculture, veterinary and biotechnology sciences that enables them to solve problems regarding sustainable development with the help of current innovative biotechnologies. Integrates basic and advanced concepts of animal biotechnology and presents future developments Describes current high-throughput next-generation whole genome and transcriptome sequencing, array-based genotyping, and modern bioinformatics approaches for sustainable livestock production Illustrates integrated strategies to dissect and decode the molecular and gene regulatory networks involved in complex quantitative yield and stress tolerance traits in livestock Ensures readers will gain a strong grasp of biotechnology for sustainable livestock production with its well-illustrated discussion

Emerging Trends in Plant Pathology

Emerging Trends in Plant Pathology PDF Author: Krishna P. Singh
Publisher: Springer Nature
ISBN: 981156275X
Category : Science
Languages : en
Pages : 849

Book Description
This book offers a comprehensive guide to the identification, detection, characterization, classification and management of plant pathogens and other beneficial microbes in agriculture. The science of plant pathology is a dynamic field and, given the growing interest in sustainable agricultural practices, plant disease management has also gained importance. Further, there has been a shift from traditional chemical-based methods to eco-friendly integrated disease management strategies with a greater focus on bio-control and other eco-friendly technologies. This book provides a comprehensive and timely account of latest concepts and advances in the field of plant pathology, including detection and diagnosis, host resistance, disease forecasting and plant biotechnological approaches. Accordingly, it will be of great interest to academics and all stakeholders working in the fields of plant pathology, microbiology, biotechnology, plant breeding, and other life sciences.

New Horizons in Wheat and Barley Research

New Horizons in Wheat and Barley Research PDF Author: Prem Lal Kashyap
Publisher: Springer Nature
ISBN: 981164134X
Category : Technology & Engineering
Languages : en
Pages : 644

Book Description
This book discusses the research progress on pathology, entomology, nematology, and resource management of wheat and barley crops. The volume summarizes the research progress and discusses the future perspectives based on current understanding of the existing issues and advancing cutting-edge technologies in the field. The book aims to help in deciding future research and development agenda by devising better strategies and techniques to cultivate these crops under clean and sustainable environment. Through this book an international group of leading wheat and barley researchers unveil the emerging concepts and issues related to biotic stresses and resource management and offers latest glimpses of technological needs and resource optimization in wheat and barley production system. Also, key topics such as frontier mechanization technologies, improved precision farming techniques, pluralistic extension and policy interventions for enhancing the resource efficiency and livelihood security of the farmers are explored here. This book is of interest to teachers, researchers, molecular breeders, cereal biochemists and biotechnologists, policymakers and professionals working in the area of wheat and barley research, food and cereal industry. Also, the book serves as an additional reading material for undergraduate and graduate students of agriculture and food sciences. National and international agricultural scientists, policy makers will also find this book to be a useful read. Volume 1 of New Horizons in Wheat and Barley Research covers global trends, breeding and quality enhancement.

Molecular Medical Microbiology

Molecular Medical Microbiology PDF Author: Yi-Wei Tang
Publisher: Academic Press
ISBN: 0323899927
Category : Science
Languages : en
Pages : 3535

Book Description
Molecular Medical Microbiology, Third Edition presents the latest release in what is considered to be the first book to synthesize new developments in both molecular and clinical research. The molecular age has brought about dramatic changes in medical microbiology, along with great leaps in our understanding of the mechanisms of infectious disease. This third edition is completely updated, reviewed and expanded, providing a timely and helpful update for microbiologists, students and clinicians in the era of increasing use of molecular techniques, changing epidemiology and prevalence, and increasing resistance of many pathogenic bacteria. Written by experts in the field, chapters include cutting-edge information and clinical overviews for each major bacterial group, along with the latest updates on vaccine development, molecular technology and diagnostic technology. Completely updated and revised edition of this comprehensive and accessible reference on molecular medical microbiology Includes full color presentations throughout Delves into in-depth discussions on individual pathogenic bacteria in a system-oriented approach Includes a clinical overview for each major bacterial group Presents the latest information on vaccine development, molecular technology and diagnostic technology Provides more than 100 chapters on all major groups of bacteria