Monitoring and Evaluation of Biomaterials and their Performance In Vivo PDF Download

Author: Roger Narayan
Publisher: Woodhead Publishing
ISBN: 0081006047
Category : Medical
Languages : en
Pages : 224

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Book Description
Monitoring and Evaluation of Biomaterials and Their Performance In Vivo provides essential information for scientists and researchers who need to assess and evaluate performance, monitor biological responses, gauge efficacy, and observe changes over time. Crucially, it also enables the optimization of design for future biomaterials and implants. This book presents readers with comprehensive coverage of the topic of in vivo monitoring of medical implants and biomaterials. Contains a specific focus on monitoring and evaluation of biomaterials in vivo Multi-faceted coverage of materials function and performance Focuses on a range of implants and subsequent bodily reactions

Author: Jean-Pierre Boutrand
Publisher: Woodhead Publishing
ISBN: 0081026447
Category : Medical
Languages : en
Pages : 586

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Book Description
Biocompatibility and Performance of Medical Devices, Second Edition, provides an understanding of the biocompatibility and performance tests for ensuring that biomaterials and medical devices are safe and will perform as expected in the biological environment. Sections cover key concepts and challenges faced in relation to biocompatibility in medical devices, discuss the evaluation and characterization of biocompatibility in medical devices, describe preclinical performance studies for bone, dental and soft tissue implants, and provide information on the regulation of medical devices in the European Union, Japan and China. The book concludes with a review of histopathology principles for biocompatibility and performance studies. Presents diverse insights from experts in government, industry and academia Delivers a comprehensive overview of testing and interpreting medical device performance Expanded to include new information, including sections on managing extractables, accelerating and simplifying medical device development through screening and alternative biocompatibility methods, and quality strategies which fasten device access to market

Author: Faheem A. Sheikh
Publisher: Springer Nature
ISBN: 9811644209
Category : Science
Languages : en
Pages : 709

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Book Description
This book reviews the interface of stem cell biology and biomaterials for regenerative medicine. It presents the applications of biomaterials to support stem cell growth and regeneration. The book discusses the stem cell interactions’ with nanofiber, gradient biomaterial, polymer- and ceramic biomaterials, integrating top-down and bottom-up approaches, adhesive properties of stem cells on materials, cell-laden hydrogels, micro-and nanospheres, de-cellularization techniques, and use of porous scaffolds. Further, this book provides a basic introduction to the fabrication techniques for creating various biomaterials that can be used for stem cell differentiation. It also elucidates the properties of stem cells, their characteristic features, tissue culture technology, properties of pluripotency, osteogenesis, and biomaterial interaction with de-cellularized organs, cell lineage in vivo and in vitro, gene expression, embryonic development, and cell differentiation. Further, the book reviews the latest applications of bio-instructive scaffold for supporting stem cell differentiation and tissue regeneration. The book also presents stem cell for dental, alveolar bone and cardiac regeneration. Lastly, it introduces engineered stem cells for delivering small molecule therapeutics and their potential biomedical applications.

Author: Maria Cristina Tanzi
Publisher: Academic Press
ISBN: 0128094591
Category : Technology & Engineering
Languages : en
Pages : 572

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Book Description
Foundations of Biomaterials Engineering provides readers with an introduction to biomaterials engineering. With a strong focus on the essentials of materials science, the book also examines the physiological mechanisms of defense and repair, tissue engineering and the basics of biotechnology. An introductory section covers materials, their properties, processing and engineering methods. The second section, dedicated to Biomaterials and Biocompatibility, deals with issues related to the use and application of the various classes of materials in the biomedical field, particularly within the human body, the mechanisms underlying the physiological processes of defense and repair, and the phenomenology of the interaction between the biological environment and biomaterials. The last part of the book addresses two areas of growing importance: Tissue Engineering and Biotechnology. This book is a valuable resource for researchers, students and all those looking for a comprehensive and concise introduction to biomaterials engineering. Offers a one-stop source for information on the essentials of biomaterials and engineering Useful as an introduction or advanced reference on recent advances in the biomaterials field Developed by experienced international authors, incorporating feedback and input from existing customers

Author: Lalit Kumar
Publisher: Elsevier
ISBN: 0323914713
Category : Technology & Engineering
Languages : en
Pages : 864

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Book Description
Nanocarriers for Drug-Targeting Brain Tumors covers different types of nanocarriers and their design and development for targeting drugs to the brain. The book also presents case studies and the mechanism of action of nanocarriers in drug targeting to a specific site. This helps researchers and clinicians understand the design, development and mechanism of action of nanocarriers. As brain tumors continue to be a significant health problem globally, and very complex for targeting drugs, conventional dosage forms are not very effective and side-effects are a major concern. Functionalized nanocarriers can address these problems. Furthermore, the targeting of nanocarriers is preferred for reducing toxicity and improving the effectiveness of the drugs. However, there is a need for understanding the design and development of formulation with the mechanism of action of nanocarriers for brain targeting. Provides information on the design and development of nanocarriers for targeting brain tumors Outlines the working principles of different nanocarriers for targeting brain tumors Includes case studies of different nanocarriers for targeting brain tumors

Author: Andreas F von Recum
Publisher: CRC Press
ISBN: 9781560324799
Category : Medical
Languages : en
Pages : 944

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Book Description
This handbook addresses the needs of those who are involved in inventing, developing, and testing implants and are concerned about the interactions between biomaterial and body tissue. The authors explore the physical, chemical, mechanical and regulatory considerations of synthetic materials used in surgical and implant procedures, and how these factors impact the latest developments and new approaches. This updated edition provides the biomaterials professional with necessary information on a range of issues, including bulk characterization, surface evaluations, toxicological evaluations, in vitro methods for safety evaluation, methods for evaluating materials in special applications, surgical considerations, systems implantology, soft and hard tissue history, regulatory aspects, and clinical trials.

Author: Sabu Thomas
Publisher: Elsevier
ISBN: 0323996914
Category : Technology & Engineering
Languages : en
Pages : 642

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Book Description
Polymeric Materials for Biomedical Implants: Characterization, Properties, and Applications offers a comprehensive guide to the various polymers utilized in the development and application of biomedical implants. These materials possess unique properties which make them ideal for use in biomedical implants, including their high degree of flexibility, ease of fabrication, non-magnetic and radio transparent properties for medical imaging, and ease of engineering for biocompatibility. The book thoroughly reviews the properties, characterization and a broad range of applications of polymeric materials in biomedical implants, bringing all key information on this important topic together under a single reference. The book's chapters cover vital topics for the development of polymeric biomedical implants, including biomaterial-tissue interactions, mechanical and surface property requirements for different implants, as well as market and ethical issues. This will be a useful reference for academics and researchers working in materials science, biomedical engineering, regenerative medicine and pharmacology, as well as R&D groups developing biomedical implants. Helps the reader make an informed choice when selecting polymeric materials for use in biomedical implants Covers a broad range of applications of biomedical implants, including cancer therapy, orthopedics, cardiovascular, biosensing and wound healing Emphasizes the importance of biocompatibility, with chapters covering toxicity and degradation aspects, as well as biomaterial-tissue interactions and the foreign body response

Author: Gaurav Sharma
Publisher: Materials Research Forum LLC
ISBN: 1644901072
Category : Technology & Engineering
Languages : en
Pages : 278

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Book Description
The book covers preparation, designing and utilization of nanohybrid materials for biomedical applications. These materials can improve the effectiveness of drugs, promote high cell growth in new scaffolds, and lead to biodegradable surgical sutures. The use of hybrid magneto-plasmonic nanoparticles may lead to non-invasive therapies. The most promising materials are based on silica nanostructures, polymers, bioresorbable metals, liposomes, biopolymeric electrospun nanofibers, graphene, and gelatin. Much research focuses on the development of biomaterials for cell regeneration and wound healing applications. Keywords: Biomedical Materials, Cell Growth, Cell Regeneration, Wound Healing, Surgical Sutures, Non-invasive Therapies , Drug Transport, Tissue Engineering, Cardiovascular Implants, Fracture Repair Implants, Biodegradable Materials, Hybrid Magneto-plasmonic Nanoparticles, Silica Nanostructures, Polymers, Bioresorbable Metals, Liposomes, Biopolymeric Electrospun Nanofibers, Graphene, Gelatin-based Hydrogels.

Author: Shakeel Ahmed
Publisher: Woodhead Publishing
ISBN: 0128216344
Category : Medical
Languages : en
Pages : 672

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Book Description
Bionanocomposites in Tissue Engineering and Regenerative Medicine explores novel uses of these in tissue engineering and regenerative medicine. This book offers an interdisplinary approach, combining chemical, biomedical engineering, materials science and pharmacological aspects of the characterization, synthesis and application of bionanocomposites. Chapters cover a broad selection of bionanocomposites including chitosan, alginate and more, which are utilized in tissue engineering, wound healing, bone repair, drug formulation, cancer therapy, drug delivery, cartilage regeneration and dental implants. Additional sections of Bionanocomposites in Tissue Engineering and Regenerative Medicine discuss, in detail, the safety aspects and circular economy of bionanocomposites – offering an insight into the commercial and industrial aspects of these important materials. Bionanocomposites in Tissue Engineering and Regenerative Medicine will prove a highly useful text for for those in the fields of biomedical engineering, chemistry, pharmaceutics and materials science, both in academia and industrial R&D groups. Each bionanocomposite type is covered individually, providing specific and detailed information for each material Covers a range of tissue engineering and regenerative medicine applications, from dental and bone engineering to cancer therapy Offers an integrated approach, with contributions from authors across a variety of related disciplines, including biomedical engineering, chemistry and materials science

Author: Imran Uddin
Publisher: Springer Nature
ISBN: 9819913500
Category : Technology & Engineering
Languages : en
Pages : 398

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Book Description
This book brings together multiple aspects of the recent research conducted in the field of nanotechnology covering topics such as the synthesis of various nanoparticles, nanorods, graphene, graphene oxide-metal composites, characterization of these materials, and ample aspects of various applications including in heavy metal sensing, optoelectronic devices, gas sensing, solar cells, biomedical sensors, role in the drug delivery, and waste-water treatment. The book is of interest to early career researchers, who are trying to grasp multiple aspects of nanomaterials and nanocomposite synthesis and its potential applications.