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Author: Hiroshi Matsuda Publisher: Springer ISBN: 4431551336 Category : Medical Languages : en Pages : 279
Book Description
This book describes the latest modalities such as tau PET imaging for diagnosis of Alzheimer’s disease and other dementias, and also provides information on handling and analyzing imaging data that is not found in other books. In addition, it introduces routine imaging studies in the management of dementia in Japan. The prevalence of dementia has increased over the past few decades, either because of greater awareness and more accurate diagnosis, or because increased longevity has created a larger population of the elderly, the age group most commonly affected. Although only clinical assessment can lead to a diagnosis of dementia, neuroimaging in dementia is recommended by most clinical guidelines, and its adjunct role has traditionally been to exclude a mass lesion rather than to support a specific diagnosis. Neuroimaging may be also helpful for developing new strategies to achieve diagnoses as early as possible for therapies aimed at slowing the progression of neurodegenerative diseases manifesting dementia. Under these conditions, all clinicians and researchers who are involved in neuroimaging for dementia should decide which patients to scan, when imaging patients is most useful, which modality to use, how to handle imaging data from many institutions, and which analytical tool to use. This edition comprises contributions from leading Japanese experts in their fields.
Author: Hiroshi Matsuda Publisher: Springer ISBN: 4431551336 Category : Medical Languages : en Pages : 279
Book Description
This book describes the latest modalities such as tau PET imaging for diagnosis of Alzheimer’s disease and other dementias, and also provides information on handling and analyzing imaging data that is not found in other books. In addition, it introduces routine imaging studies in the management of dementia in Japan. The prevalence of dementia has increased over the past few decades, either because of greater awareness and more accurate diagnosis, or because increased longevity has created a larger population of the elderly, the age group most commonly affected. Although only clinical assessment can lead to a diagnosis of dementia, neuroimaging in dementia is recommended by most clinical guidelines, and its adjunct role has traditionally been to exclude a mass lesion rather than to support a specific diagnosis. Neuroimaging may be also helpful for developing new strategies to achieve diagnoses as early as possible for therapies aimed at slowing the progression of neurodegenerative diseases manifesting dementia. Under these conditions, all clinicians and researchers who are involved in neuroimaging for dementia should decide which patients to scan, when imaging patients is most useful, which modality to use, how to handle imaging data from many institutions, and which analytical tool to use. This edition comprises contributions from leading Japanese experts in their fields.
Author: Alison D. Murray Publisher: Elsevier Health Sciences ISBN: 1455742945 Category : Medical Languages : en Pages : 136
Book Description
Dementia is a massive and increasing global problem, with the current prevalence anticipated to double every 20 years as people live longer. Neuroimaging in dementia is recommended by most clinical guidelines and its role has traditionally been to exclude a mass lesion, rather than to support a specific diagnosis. All radiologists will be aware of a steady rise in the number of requests for brain imaging in old people, but what can imaging reliably tell us and what kind of imaging should we use? In affluent societies we now have a range of structural and molecular brain imaging techniques at our disposal, with specific ligands and sophisticated image analysis techniques now available for clinical use. However, we have difficulty justifying which patients to scan, using which modality and when. We know that Alzheimer’s disease is the most common neuropathology contributing to a diagnosis of Alzheimer’s disease but we also know from large post-mortem studies that most brain pathology in those who have died with a diagnosis of dementia is mixed. Thus understanding different diseases that can cause dementia, how these co-exist or interact and appreciating that not all dementia is Alzheimer’s disease is important. Equally important is awareness of individual differences in response to a neuropathological burden and what factors provide resilience against dementia that might be maximized to reduce or postpone its impact. This issue draws together contributions from experts in their fields to provide clarity to the topic in a comprehensive collection of articles.
Author: Frederik Barkhof Publisher: Springer Science & Business Media ISBN: 3642008186 Category : Medical Languages : en Pages : 278
Book Description
This up-to-date, superbly illustrated book is a practical guide to the effective use of neuroimaging in the patient with cognitive decline. It sets out the key clinical and imaging features of the various causes of dementia and directs the reader from clinical presentation to neuroimaging and on to an accurate diagnosis whenever possible. After an introductory chapter on the clinical background, the available "toolbox" of structural and functional neuroimaging techniques is reviewed in detail, including CT, MRI and advanced MR techniques, SPECT and PET, and image analysis methods. The imaging findings in normal ageing are then discussed, followed by a series of chapters that carefully present and analyze the key findings in patients with dementias. Throughout, a practical approach is adopted, geared specifically to the needs of clinicians (neurologists, radiologists, psychiatrists, geriatricians) working in the field of dementia, for whom this book will prove an invaluable resource.
Author: Robert C. Green Publisher: Professional Communications ISBN: 1884735967 Category : Alzheimer's disease Languages : en Pages : 259
Book Description
Differential diagnosis of Alzheimer's disease, dementia and delirium, diagnostic tests in differential diagnosis, and identifying underlying conditions that can cause dementia are discussed. Covers drugs to treat cognitive symptoms, managment of agitation and behavioral symptoms, patient management, and support services.
Author: Tapan Khan Publisher: Academic Press ISBN: 0128051477 Category : Science Languages : en Pages : 276
Book Description
Biomarkers in Alzheimer’s Disease provides a comprehensive overview of all modalities of Alzheimer’s disease biomarkers, including neuroimaging, cerebrospinal fluid, genomic, and peripheral systems. Each chapter integrates molecular/cellular abnormality due to Alzheimer’s disease and technological advancement of biomarkers techniques. The book is ideal for clinical neuroscience and molecular/cellular neuroscience researchers, psychiatrists, and allied healthcare practitioners involved in the diagnosis and management of patients with cognitive impairment and Alzheimer’s disease, and for differential diagnosis of Alzheimer’s disease with other non-Alzheimer’s dementia. Presents a comprehensive overview detailing all modalities of Alzheimer’s disease biomarkers Written for neuroscience researchers and clinicians studying or treating patients with Alzheimer’s Disease Integrates, in each chapter, the molecular/cellular abnormality due to Alzheimer’s disease and the technological advancement of biomarkers techniques
Author: Suzanne De La Monte Publisher: ISBN: 9789535167853 Category : Languages : en Pages : 378
Book Description
The Clinical Spectrum of Alzheimer's Disease: The Charge Toward Comprehensive Diagnostic and Therapeutic Strategies is highly informative and current. Acknowledged experts in the field critically review both standard and under-appreciated clinical, behavioral, epidemiological, genetic, and neuroimaging attributes of Alzheimer's disease. The collection covers diverse topics of interest to clinicians and researchers alike. Experienced professionals and newcomers to the field will benefit from the read. The strengths and weaknesses of current clinical, non-invasive, neuro-imaging, and biomarker diagnostic approaches are explained. The perspectives give fresh insights into the process of neurodegeneration. Readers will be enlightened by the evidence that the neural circuits damaged by neurodegeneration are much broader than conventionally taught, suggesting that Alzheimer's could be detected at earlier stages of disease by utilizing multi-pronged diagnostic approaches. This book inspires renewed hope that more effective treatments could be developed based upon the expanding list of potential therapeutic targets.
Author: Andrew E. Budson Publisher: John Wiley & Sons ISBN: 1118672852 Category : Psychology Languages : en Pages : 676
Book Description
The reference is a broad-ranging review of Alzheimer's disease and other dementias from both basic and clinical neuroscience perspectives; it provides scientists and medical professionals with an extensive introduction and an up-to-date review of cutting-edge scientific advances. Brings the reader up-to-date with cutting-edge developments in this exciting and fast-paced field Summarizes the most recent developments in the fields of Alzheimer's disease and dementia Brings together articles from a prominent and international group of contributors Encompasses a unique range of topics, combining basic molecular perspectives and cognitive neurosciences
Author: Massimo Filippi Publisher: Springer Nature ISBN: 3030667731 Category : Medical Languages : en Pages : 138
Book Description
This book helps physicians select from among the currently available imaging tools, promoting the correct and cost-saving diagnosis and management of common dementias. Magnetic resonance (MR) and nuclear medicine techniques are routinely used to facilitate diagnosis, select therapies, provide information regarding the prognosis, and monitor therapy response in patients with cognitive impairment and dementia. Furthermore, the advent of quantitative MR techniques, such as diffusion-weighted imaging, perfusion imaging, etc. have opened up new opportunities to diagnose neurological diseases based on objective findings, and offer unique new insights into the main neurodegenerative diseases of the human brain. However, the practical value of various neuroimaging techniques in clinical practice has yet to be clearly defined, and their potential for future development is not yet fully appreciated. To help remedy the situation, this book offers practical and useful algorithms and rules that can be directly applied in the clinical setting. It provides concise content, together with a wealth of clinical case material.
Author: Klaus P. Ebmeier Publisher: Karger Medical and Scientific Publishers ISBN: 3805575955 Category : Medical Languages : en Pages : 137
Book Description
Single photon emission computerized tomography (SPECT) is a relatively cheap and widely available instrument for the examination of brain perfusion, cerebral blood flow and activity of neurotransmitter systems. The European project 'SPECT in dementia' sets out to overcome some of the factors holding back the development of clinical neuroimaging. It has developed a methodology for combining results from different imaging centres, at the same time making scan assessment more objective and powerful. Moreover, using objective voxel-based methods of image analysis improves the diagnostic performance of less-experienced clinicians and contributes to their training. This publication gives an excellent general overview of the new methods of image analysis and sharing. It is complemented by a systematic review of the diagnostic utility of SPECT in dementia and a cost-effectiveness model of diagnostic improvements in Alzheimers disease. This book is essential reading for all scientists, economists and clinicians in geriatric medicine, neurology and psychiatry, neuro-radiology and nuclear medicine working with patients suffering from dementia and Alzheimer's disease, who want to stay ahead in this rapid developing field.
Author: Hiroshi Matsuda
Author: Hiroshi Matsuda
Author: Alison D. Murray
Author: Frederik Barkhof
Author: Robert C. Green
Author: Tapan Khan
Author: Suzanne De La Monte
Author: Andrew E. Budson
Author: Massimo Filippi
Author: Walter George Bradley
Author: Klaus P. Ebmeier