OECD Series on Testing and Assessment Overview on genetic toxicology TGs PDF Download

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OECD Series on Testing and Assessment Overview on genetic toxicology TGs

OECD Series on Testing and Assessment Overview on genetic toxicology TGs PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264274766
Category :
Languages : en
Pages : 60

Book Description
Following a general update of the Genetic Toxicology TGs in 2015, the present Document was written to provide succinct and useful information to individuals unfamiliar with genetic toxicology testing, as well as experienced individuals wishing to obtain an overview of the recent changes that ...

OECD Series on Testing and Assessment Overview on genetic toxicology TGs

OECD Series on Testing and Assessment Overview on genetic toxicology TGs PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264274766
Category :
Languages : en
Pages : 60

Book Description
Following a general update of the Genetic Toxicology TGs in 2015, the present Document was written to provide succinct and useful information to individuals unfamiliar with genetic toxicology testing, as well as experienced individuals wishing to obtain an overview of the recent changes that ...

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264078495
Category :
Languages : en
Pages : 112

Book Description
These Guidance Notes outline core concepts in order to obviate the need to consult large numbers of text books, while still pointing the reader to sources of more detailed or specific information.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Repeat-Dose Toxicity Studies

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Repeat-Dose Toxicity Studies PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264078487
Category :
Languages : en
Pages : 87

Book Description
This document presents a general guide to the analysis and evaluation of data from studies involving repeated exposures of toxicity test species to pesticides and other chemicals.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 481: Genetic Toxicology: Saacharomyces cerevisiae, Miotic Recombination Assay

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 481: Genetic Toxicology: Saacharomyces cerevisiae, Miotic Recombination Assay PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264071423
Category :
Languages : en
Pages : 6

Book Description
This assay may be used to measure mitotic recombination (gene conversion or crossingover) in yeast, a eukaryotic micro-organism. Crossing-over is generally assayed by the production of recessive homozygous colonies or sectors produced in a ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 488: Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 488: Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264203907
Category :
Languages : en
Pages : 28

Book Description
This Test Guideline describes an in vivo assay that detects chemicals that may induce gene mutations in somatic and germ cells. In this assay, transgenic rats or mice that contain multiple copies of chromosomally integrated plasmid or phage shuttle vectors are used. The transgenes contain reporter genes for the detection of various types of mutations induced by test chemicals.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264078495
Category :
Languages : en
Pages : 113

Book Description
These Guidance Notes outline core concepts in order to obviate the need to consult large numbers of text books, while still pointing the reader to sources of more detailed or specific information. They are intended to complement OECD Test Guidelines.

OECD Series on Testing and Assessment Fish Toxicity Testing Framework

OECD Series on Testing and Assessment Fish Toxicity Testing Framework PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264221433
Category :
Languages : en
Pages : 174

Book Description
This document presents a review of fish toxicity testing for the regulatory purpose of chemical safety. The main focus is on fish toxicity, but fish bioaccumulation is also considered where relevant.

Handbook of Laboratory Animal Science

Handbook of Laboratory Animal Science PDF Author: Jann Hau
Publisher: CRC Press
ISBN: 0429801599
Category : Medical
Languages : en
Pages : 1890

Book Description
Building upon the success of previous editions of the bestselling Handbook of Laboratory Animal Science, first published in 1994, this latest revision combines all three volumes in one definitive guide. It covers the essential principles and practices of Laboratory Animal Science as well as selected animal models in scientific disciplines where much progress has been made in recent years. Each individual chapter focuses on an important subdiscipline of laboratory animal science, and the chapters can be read and used as stand-alone texts, with only limited necessity to consult other chapters for information. With new contributors at the forefront of their fields, the book reflects the scientific and technological advances of the past decade. It also responds to advances in our understanding of animal behavior, emphasizing the importance of implementing the three Rs: replacing live animals with alternative methods, reducing the number of animals used, and refining techniques to minimize animal discomfort. This fourth edition will be useful all over the world as a textbook for laboratory animal science courses for postgraduate and undergraduate students and as a handbook for scientists who work with animals in their research, for university veterinarians, and for other specialists in laboratory animal science.

Handbook of Substance Misuse and Addictions

Handbook of Substance Misuse and Addictions PDF Author: Vinood B. Patel
Publisher: Springer Nature
ISBN: 3030923924
Category : Medical
Languages : en
Pages : 3261

Book Description
Substance misuse and addictions are a public health issue. They affect the well-being of each community and nation as a whole. It is, therefore, necessary to identify, educate, and treat individuals who are addicted to substances. Policies and procedures go hand-in-hand with public health education and safety. The science behind the public health issues of one drug may be applicable to other drugs as well. However, marshalling all of the aforementioned information into a single source is somewhat difficult due to the wide array of material. The Editors address this by compiling the research in this single reference work that serves as a "one-stop-shopping" approach to everything readers need to know about the scientific basis of public health and addictions and agents of misuse. Apart from active agents that have a plant or chemical basis, there is a need to consider that there are other forms of addiction which may have common modes of causality or prevention. These include food addiction, gaming, gambling, and other non-drug addictions. These types of addiction may be related to the addiction of drugs. The Handbook of Substance Misuse and Addictions: From Biology to Public Health offers a holistic understanding of the relationship between public health and substance misuse. The text provides a common platform upon which other forms of addiction or substance misuse can be understood and treated. Addiction processes involve understanding the biological processes as well as behavior, psychology, sociology, and public health, all of which are interlinked. This Handbook is a useful reference for lecturers, students, researchers, practitioners, and other professionals in public health, addiction science, epidemiology, health education, health promotion, and health sciences.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Document on Classification Systems for Reproductive Toxicity in OECD Member Countries

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Document on Classification Systems for Reproductive Toxicity in OECD Member Countries PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264078339
Category :
Languages : en
Pages : 24

Book Description
This detailed review document examines member country classification systems for reproductive toxicity.