Author: Robert L. LipnickPublisher:
ISBN:
Category :
Languages : en
Pages : 276
Book Description
Persistent, Bioaccumulative, and Toxic Chemicals II
Author: Robert L. LipnickPERSISTENT BIOACCUMULATIVE TOXI
Author: ABELKOPPublisher: CRC Press
ISBN: 9781138792944
Category :
Languages : en
Pages : 303
Book Description
Developed from the efforts of a multiyear, international project examining how persistent, bioaccumulative, and toxic (PBT) chemicals are evaluated and managed, Persistent, Bioaccumulative, and Toxic (PBT) Chemicals: Technical Aspects, Policies, and Practices focuses on improving the processes that govern PBTs. Incorporating science and policy literature�as well as interviews and panel discussions featuring experts from around the world�this book provides you with an international perspective of PBT policies (centering on Europe, Asia, and North America), and reveals major findings and recommendations for improving PBT science, laws, and policies. It includes case studies of specific chemicals, provides an introduction to the overall subject of toxic chemicals, and weighs in on science and policy expansion for PBTs. It also provides summary tables of important PBTs, and discussions on the number of PBTs in commerce, weight of evidence approaches, market deselection, and international management. The text: Assesses the history, current practice, and future of PBT management Considers the roles scientific data, modeling, and conventions play in identifying and regulating PBTs Explores the number of PBTs in commerce and the growing role of weight of evidence (WOE) in the making of PBT determinations Identifies issues that are likely to come up in WOE judgments Examines international, national, subnational, and regional PBT policies Includes a comprehensive and easy-to-understand analysis of PBT science and policy This book reviews the current science, policies, and practices surrounding the regulation of PBTs. It also provides relevant research, recommendations, and suggestions for improving the management and oversight of PBTs.
Persistent, Bioaccumulative, and Toxic (PBT) Chemicals
Author: Adam D. K. AbelkopPublisher: CRC Press
ISBN: 1482298783
Category : Science
Languages : en
Pages : 303
Book Description
Developed from the efforts of a multiyear, international project examining how persistent, bioaccumulative, and toxic (PBT) chemicals are evaluated and managed, Persistent, Bioaccumulative, and Toxic (PBT) Chemicals: Technical Aspects, Policies, and Practices focuses on improving the processes that govern PBTs. Incorporating science and policy literature—as well as interviews and panel discussions featuring experts from around the world—this book provides you with an international perspective of PBT policies (centering on Europe, Asia, and North America), and reveals major findings and recommendations for improving PBT science, laws, and policies. It includes case studies of specific chemicals, provides an introduction to the overall subject of toxic chemicals, and weighs in on science and policy expansion for PBTs. It also provides summary tables of important PBTs, and discussions on the number of PBTs in commerce, weight of evidence approaches, market deselection, and international management. The text: Assesses the history, current practice, and future of PBT management Considers the roles scientific data, modeling, and conventions play in identifying and regulating PBTs Explores the number of PBTs in commerce and the growing role of weight of evidence (WOE) in the making of PBT determinations Identifies issues that are likely to come up in WOE judgments Examines international, national, subnational, and regional PBT policies Includes a comprehensive and easy-to-understand analysis of PBT science and policy This book reviews the current science, policies, and practices surrounding the regulation of PBTs. It also provides relevant research, recommendations, and suggestions for improving the management and oversight of PBTs.
Persistent, Bioaccumulative, and Toxic Chemicals II
Author: Robert Louis LipnickPublisher:
ISBN:
Category : Medical
Languages : en
Pages : 298
Book Description
This work is "aimed at examining persistent, bioaccumulative, toxic chemicals that undergo slow environmental degradation in air, water, and soil, bioaccumulate in fish and other organisms, and exhibit a high degree of toxicity. This volume examines the fate and behavior of these chemicals, and their food chain transfer and exposure. Chapters cover recent research results and reviews related to polychlorinated biphenyls (PCBs), butyltin, toxaphene, dioxin, alpha-hexachlorocyclohexane and mercury."--Publisher.
Fate and Exposure
Author: Persistent, Bioaccumulative, and Toxic Chemicals I
Author: Robert Louis LipnickPublisher:
ISBN:
Category : Persistent pollutants
Languages : en
Pages : 328
Book Description
This is part of a two-book assessment of hydrolase structure/functionrelationships and the means by which these important enzymes can be betterutilized. Each book, Assessment and Emerging New Chemicals and Fate andExposure, will deal with understanding cellulase and hemicellulase action - astrategy based in macromolecular modeling, site-directed mutagenesis, activesite mapping, heterologous expression, and classical kinetic characterization.Information about new cellulase enzymes and systems and trends in the field ofglycosyl hydrolase biochemistry will be examined as well as new crystallographicstructure of important cellulases and methods for improving activity by proteinengineers.
Persistent, Bioaccumulative and Toxic Chemicals
Author: A Framework to Guide Selection of Chemical Alternatives
Author: National Research CouncilPublisher: National Academies Press
ISBN: 0309310164
Category : Science
Languages : en
Pages : 280
Book Description
Historically, regulations governing chemical use have often focused on widely used chemicals and acute human health effects of exposure to them, as well as their potential to cause cancer and other adverse health effects. As scientific knowledge has expanded there has been an increased awareness of the mechanisms through which chemicals may exert harmful effects on human health, as well as their effects on other species and ecosystems. Identification of high-priority chemicals and other chemicals of concern has prompted a growing number of state and local governments, as well as major companies, to take steps beyond existing hazardous chemical federal legislation. Interest in approaches and policies that ensure that any new substances substituted for chemicals of concern are assessed as carefully and thoroughly as possible has also burgeoned. The overarching goal of these approaches is to avoid regrettable substitutions, which occur when a toxic chemical is replaced by another chemical that later proved unsuitable because of persistence, bioaccumulation, toxicity, or other concerns. Chemical alternative assessments are tools designed to facilitate consideration of these factors to assist stakeholders in identifying chemicals that may have the greatest likelihood of harm to human and ecological health, and to provide guidance on how the industry may develop and adopt safer alternatives. A Framework to Guide Selection of Chemical Alternatives develops and demonstrates a decision framework for evaluating potentially safer substitute chemicals as primarily determined by human health and ecological risks. This new framework is informed by previous efforts by regulatory agencies, academic institutions, and others to develop alternative assessment frameworks that could be operationalized. In addition to hazard assessments, the framework incorporates steps for life-cycle thinking - which considers possible impacts of a chemical at all stages including production, use, and disposal - as well as steps for performance and economic assessments. The report also highlights how modern information sources such as computational modeling can supplement traditional toxicology data in the assessment process. This new framework allows the evaluation of the full range of benefits and shortcomings of substitutes, and examination of tradeoffs between these risks and factors such as product functionality, product efficacy, process safety, and resource use. Through case studies, this report demonstrates how different users in contrasting decision contexts with diverse priorities can apply the framework. This report will be an essential resource to the chemical industry, environmentalists, ecologists, and state and local governments.
Comparative Qsar
Author: James DevillersPublisher: CRC Press
ISBN: 9781560327165
Category : Science
Languages : en
Pages : 386
Book Description
As the 21st century approaches, there is little doubt that the tools and resources are available to unlock all the secrets of Quantitative Structure-Activity Relationships (QSAR) in order to design more efficient drugs and safer chemicals. The comparison QSAR models provide are a key to reach a deep understanding of the foundation and a better optimisation of the use of these statistical tools. Seeking out the similarities and differences among QSAR Models allows the user to estimate their simulation performances, find chemo-taxonomical links, and uncover In vivo/In Vitro relationships. The purpose of this book is to highlight the multifaceted aspect of the term "comparative QSAR" by bringing together QSAR experts of various origins and allowing them to offer their views on this diverse subject.
Persistent, Bioaccumulative, and Toxic Chemicals
Author: Robert L. LipnickPublisher:
ISBN: 9780841236745
Category :
Languages : en
Pages : 0
Book Description