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Author: Alberto Lodola Publisher: John Wiley & Sons ISBN: 0470922729 Category : Medical Languages : en Pages : 280
Book Description
This book describes, with references to key source materials, the background to, and conduct of, the principal nonclinical studies that are central to drug development. The chapters provide an understanding of the key components of the preclinical phase of drug development with a hands-on description, with core chapters addressing study conduct, types, and reporting. As such, it is a practical guide through toxicology testing and an up-to-date reference on current issues, new developments, and future directions in toxicology. Opening with a practical description of toxicology and its role in the development of pharmaceuticals, the book proceeds to detail international regulations (including the impact of the new REACH standards for chemical safety), interdisciplinary interactions among scientists in drug development, steps in toxicity testing, and risk management. Further, the book covers the methods of genetic toxicology (assays, genomics, in vivo screening) as a complement to “traditional” toxicology in the risk assessment and risk management of pharmaceuticals.
Author: Alberto Lodola Publisher: John Wiley & Sons ISBN: 0470922729 Category : Medical Languages : en Pages : 280
Book Description
This book describes, with references to key source materials, the background to, and conduct of, the principal nonclinical studies that are central to drug development. The chapters provide an understanding of the key components of the preclinical phase of drug development with a hands-on description, with core chapters addressing study conduct, types, and reporting. As such, it is a practical guide through toxicology testing and an up-to-date reference on current issues, new developments, and future directions in toxicology. Opening with a practical description of toxicology and its role in the development of pharmaceuticals, the book proceeds to detail international regulations (including the impact of the new REACH standards for chemical safety), interdisciplinary interactions among scientists in drug development, steps in toxicity testing, and risk management. Further, the book covers the methods of genetic toxicology (assays, genomics, in vivo screening) as a complement to “traditional” toxicology in the risk assessment and risk management of pharmaceuticals.
Author: Ali S. Faqi Publisher: Academic Press ISBN: 0123878152 Category : Business & Economics Languages : en Pages : 904
Book Description
A Comprehensive Guide to Toxicology in Preclinical Drug Development is designed for toxicologists who need a thorough understanding of the drug development process. This multi-contributed reference will provide a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics --
Author: Ira S. Richards Publisher: Jones & Bartlett Learning ISBN: 1284065995 Category : Medical Languages : en Pages : 475
Book Description
All public health professionals should have some level of knowledge of the basic principles of Toxicology. Whether dealing with issues as diverse as a workers’ compensation claim for a job-related exposure and injury or the removal of toxic wastes from an urban community, public health professionals must be able to communicate with each other, the public, and our political leaders concerning how chemicals can, and the conditions under which they may, realistically produce harm. Principles and Practice of Toxicology in Public Health provides students with an understanding of the nature and scope of the discipline, so that they may be prepared to participate in a meaningful way in the often highly visible problem-solving and decision-making processes required of public health professionals. In four sections, it offers an introduction to the field, as well as the basics of toxicology principles, systemic toxicity, and toxicology practice. The text is immediately readable for the student with little technical background. The Second Edition is a thorough update that has been expaneded with a new chapter on endocrine toxicology. Instructor Resources: Instructor Manual, PowerPoint, TestBank
Author: Antonio Peña-Fernández Publisher: ISBN: 9781032100227 Category : Chemicals Languages : en Pages :
Book Description
"There is an increasing need for knowledge of toxicology to safeguard the use of chemicals in industry, public and private sectors. The study of toxicology is becoming increasingly relevant in human health sciences, as future health and clinical professionals will be pivotal to address and manage emerging chemical threats and hazards related to modern anthropogenic activities and technological development. Comprising a series of chapters from leading toxicology, pharmacy and public health academics and experts across Europe, the United States and beyond, Toxicology for the Health and Pharmaceutical Sciences provides a concise yet comprehensive volume that can be used as a relevant textbook on toxicology for the clinical, healthcare, educational and professional sectors. This book covers the fundamentals and recent developments in toxicology, to respond to local and global chemical, pharmaceutical and environmental threats. Thus, this volume has chapters specifically designed to support the understanding of the most current, toxicology-related subjects for any undergraduate/postgraduate health programmes, as well as aiding with the delivery of continuing professional development training on up-to-date topics in toxicology for current practicing health professionals wishing to improve their background knowledge in toxicology. The book is also vital reading, and reference for policy makers, and others that influence, and decide regulations that have an impact on the environment, and human health"--
Author: Donald G. Barceloux Publisher: John Wiley & Sons ISBN: 1118382765 Category : Science Languages : en Pages : 1196
Book Description
Interest and information in the field of medical toxicology has grown rapidly, but there has never been a concise, authoritative reference focused on the subjects of natural substances, chemical and physical toxins, drugs of abuse, and pharmaceutical overdoses. Medical Toxicology of Natural Substances finally gives you an easily accessible resource for vital toxicological information on foods, plants, and animals in key areas in the natural environment.
Author: Michael J. Derelanko Publisher: CRC Press ISBN: 1439890137 Category : Law Languages : en Pages : 1027
Book Description
The Handbook of Toxicology, Third Edition provides an updated practical reference source for practicing toxicologists in the pharmaceutical and chemical industries, contract laboratories, regulatory agencies, and academia. Written by experts in their specific toxicology fields, the chapters provide both fundamental and applied information. Topics range from General Toxicology, to Genetic Toxicology, Human Clinical Toxicology, Histopathology, Clinical Pathology, Metabolism and Toxicokinetics, Risk Assessment, and more. New to this edition: Completely rewritten chapters covering immunotoxicology, endocrine toxicology, and reproductive and developmental toxicology, providing a fresh perspective on these topics Addition of new chapters on Chemical Toxicology, Pharmaceutical Toxicology, Juvenile Toxicology, and Safety Pharmacology Updated information dealing with Inhalation Toxicology, Neurotoxicology, and Regulatory Toxicology, which has been consolidated into single chapters for each specialty A separate glossary with toxicological terms presented both alphabetically and by toxicological subspecialty For nearly 20 years, this handbook has remained the only reference book of its kind, designed to facilitate easy access to information related to the various toxicology specialties. This updated edition of a popular reference book reflects current practices and the state of the science of toxicology.
Author: Vij Publisher: Elsevier India ISBN: 9788131211298 Category : Languages : en Pages : 776
Book Description
The book is a comprehensive and authoritative exposition of Forensic Medicine and Toxicology. It provides precise and useful information on relevant legal provisions and forensic anatomy, and promotes interdisciplinary understanding of issues where law an medicine converge. The text is oriented towards the practical problems ncountered during day-to-day medicollegal work. About the Author : - Krishnan Vij, MD, L.L.B. is Professor and Head, Department of Forensic Medicine and Toxicology, Government Medical College & Hospital, Chandigarh, India.
Author: Yvonne Will Publisher: John Wiley & Sons ISBN: 1119053331 Category : Medical Languages : en Pages : 598
Book Description
As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process. • Guides researchers as to what drug safety experiments are both practical and useful • Covers a variety of key topics – safety lead optimization, in vitro-in vivo translation, organ toxicology, ADME, animal models, biomarkers, and –omics tools • Describes what experiments are possible and useful and offers a view into the future, indicating key areas to watch for new predictive methods • Features contributions from firsthand industry experience, giving readers insight into the strategy and execution of predictive toxicology practices
Author: Antonio Peña-Fernández Publisher: CRC Press ISBN: 9781138303362 Category : Chemicals Languages : en Pages : 520
Book Description
Comprising a series of chapters from leading toxicology, pharmacy and public health academics and experts across Europe, the United States and beyond, this book covers the fundamentals and recent developments in toxicology, to respond to local and global chemical, pharmaceutical and environmental threats.
Author: Alberto Lodola
Author: Alberto Lodola
Author: Ali S. Faqi
Author: Ira S. Richards
Author: Antonio Peña-Fernández
Author: Donald G. Barceloux
Author: Michael J. Derelanko
Author: Vij
Author: Yvonne Will
Author: Leslie M. Shaw
Author: Antonio Peña-Fernández