Principles of Drug Therapy in Neurology PDF Download

Author: Michael V. Johnston
Publisher: Oxford University Press, USA
ISBN:
Category : Medical
Languages : en
Pages : 394

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Book Description
Once considered largely untreatable, neurologic disorders have become the newest frontier for breakthrough research in pharmacology. Principles of Drug Therapy in Neurology discusses the latest investigatinal strategies and theories and how they affect current clinical practice. The book details the mechanisms, delivery systems, and efficacy of the latest medication, as the editors outline a "method" for thinking about the action of clinically useful drugs, based on modern information about kinetics, transport to the brain, interaction with neurotransmitter systems and membrane action, etc. All types of major neurologic disorders are discussed.

Author: Michael V. Johnston
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 594

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Book Description
Principles of Drug Therapy, Second Edition provides comprehensive coverage of current drug therapy in neurology while providing the background information that neurologists and other clinicians need to understand its rationale. The range of new drugs available for treatment of neurological disorders is expanding rapidly along with rapid advances in the neurosciences that are uncovering disease mechanisms. Although there are many sources of drug information, most are limited to basic information about indications, dose and side effects. However the complexity of the nervous system is enormous and the information needed to understand drug effects is accordingly often not readily available in a single source. The book addresses that issue by presenting 18 focused, disease-related chapters by authors who are expert clinical sub-specialists as well as experts on drug therapy. The first chapter on fundamentals of drug therapy in neurology provides a readable synopsis of how the classic pharmacology concepts such as pharmacodynamics and pharmacokinetics are related to therapy in neurology. This section also discusses the pathogenesis of potentially serious side effects such as skin rashes and liver disorders, and the role of pharmacogenetics in both drug effect and side effects. Outstanding chapters on movement disorders, epilepsy, and headaches cover major areas of drug treatment in neurology practice. Additional chapters cover stroke, increased intracranial pressure in the intensive care unit, dementia, multiple sclerosis, spinal cord injury and spasticity, neuromuscular disorders and pain. Sleep, central nervous system infections and HIV, and drug intoxications are also covered. Areas of special interest to child neurologists covered in the book include treatment of genetic metabolic disorders and use of stimulants and other medications for childhood cognitive disorders. An excellent chapter is also provided on drug treatment of psychiatric disorders because of the important of psychiatric drugs in neurology practice. This edition has been completely re-written from the successful edition published in the 90s and enlarged commensurate with the exciting progress in treatment in neurology.

Author: Hiroaki Naritomi
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318023086
Category : Medical
Languages : en
Pages : 162

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Book Description
A compilation of innovative findings and new directions in neurological recovery After decades of focusing on how to alleviate and prevent recurrence of acute CNS injuries, the emphasis has finally shifted towards repairing such devastating events and rehabilitation. This development has been made possible by substantial progress in understanding the scientific underpinnings of recovery as well as by novel diagnostic tools, and most importantly, by emerging therapies awaiting clinical trials. In this publication, several international experts introduce novel areas of neurological reorganization and repair following CNS damage. Principles and methods to monitor and augment neuroplasticity are explored in depth and supplemented by a critical appraisal of neurological repair mechanisms and possibilities to curtail disability using computer or robotic interfaces. Rather than providing a textbook approach of CNS restoration, the editors selected topics where progress is most imminent in this labyrinthine domain of medicine. Moreover, the varied background and origins of the contributors lend this book a truly global perspective on the current state of affairs in neurological recovery.

Author: Simon Shorvon
Publisher: John Wiley & Sons
ISBN: 1118936981
Category : Medical
Languages : en
Pages : 1072

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Book Description
Highly Commended at the British Medical Association Book Awards 2016 The Treatment of Epilepsy, fourth edition, is a comprehensive reference and clinical guide to the pharmacological, medical and surgical options available in the treatment of epilepsy. The text is compiled by a group of internationally renowned editors and contributors and is now in full color and extensively illustrated The first two sections cover the background to, and principles of, treatment in different clinical situations Section three comprises a series of systematic reviews of contemporary drug therapy, devoting one chapter to each anti-epileptic drug and covering all clinically-relevant aspects Section four focuses on the surgical options, devoting individual chapters to each of the modalities of presurgical assessment and to each surgical operation or approach This 4th edition is extensively revised incorporating the many recent developments in therapy, and comprises 81 chapters from world experts from 18 countries

Author: Chrysostomos P. Panayiotopoulos
Publisher: Springer
ISBN:
Category : Medical
Languages : en
Pages : 570

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Book Description
This book gives an exhaustive account of the classification and management of epileptic disorders. It provides clear didactic guidance on the diagnosis and treatment of epileptic syndromes and seizures through thirteen chapters, complemented by a pharmacopoeia and CD ROM of video-EEGs.

Author: Russell R. Lonser
Publisher: Academic Press
ISBN: 0128139986
Category : Medical
Languages : en
Pages : 556

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Book Description
Nervous System Drug Delivery: Principles and Practice helps users understand the nervous system physiology affecting drug delivery, the principles that underlie various drug delivery methods, and the appropriate application of drug delivery methods for drug- and disease-specific treatments. Researchers developing nervous system putative therapeutic agents will use this book to optimize drug delivery during preclinical assessment and to prepare for regulatory advancement of new agents. Clinicians will gain direct insights into pathophysiologic alterations that impact drug delivery and students and trainees will find this a critical resource for understanding and applying nervous system drug delivery techniques. Offers an up-to-date, comprehensive resource on drug delivery to the nervous system Provides a bridge for understanding across nervous system delivery-related physiology, drug delivery principles. and the methodologies that underlie the various methods of drug distribution (with clinical application) Written for a broad audience of researchers, clinicians and advanced graduate students in neuroscience, neurology, neurosurgery, pharmacology, radiology and psychiatry

Author: David E. Golan
Publisher: Lippincott Williams & Wilkins
ISBN: 1608312704
Category : Medical
Languages : en
Pages : 978

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Book Description
Now in its third edition, Principles of Pharmacology presents content in a conceptual framework that maximizes understanding and retention and minimizes rote memorization. It takes students "beyond the disease" and deep into physiologic, biochemical, and pathophysiologic systems where drugs activate or inhibit these systems by interacting with molecular and cellular targets. This unique approach ensures understanding of the mechanisms of drug actions on the body, and ultimately, in treating the human patient. Ideal for introductory pharmacology courses that emphasize critical thinking, molecular understanding, systems-based integration, and clinical preparation, the text: Features chapter-opening clinical cases and questions to establish a context for the discussion and the answers that follow Presents signature drug summary tables, updated and organized by mechanism of action, with information on clinical applications, adverse effects, contraindications, and therapeutic considerations Incorporates NEW full-color illustrations throughout, suiting the needs of visual learners and more effectively presenting concepts covered in the narrative Integrates timely content, including recently approved drugs as well as current research on drug mechanisms of action Delivers course and review material appropriate for students through a uniquely collaborative authorship consisting of medical students, residents, and faculty

Author: Joel E. Houglum
Publisher: SLACK Incorporated
ISBN: 1556429010
Category : Medical
Languages : en
Pages : 482

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Book Description
Principles of Pharmacology for Athletic Trainers, Second Edition has expanded the comprehensive and unique aspect of pharmacology presented in the best-selling first edition by introducing new information on: * Drug and treatment strategies. * Aspects of Type 1 and Type 2 diabetes, including treatment strategies, the disease process, diagnosis & monitoring of diabetes, and issues that are important for the athletic trainer. * The foundational concepts and pharmacological treatment of schizophrenia, depression, bipolar disorder, various anxiety disorders, and attention deficit-hyperactivity disorder. * Discussion of herbal supplements, federal regulations, and safety & quality issues related to herbal supplements. Dr. Joel Houglum and Dr. Gary Harrelson have updated Principles of Pharmacology for Athletic Trainers, Second Edition to be more user-friendly by incorporating revised information on pharmacokinetic and pharmacodynamic principles, making it even easier for students to understand, while still providing the depth of information desired by faculty. Features of the Second Edition: * Educational prompts are provided in each chapter in the form of an advanced chapter organizer. * Shadow boxes throughout to remind students of previously discussed topics. * Summaries at the end of each section to reinforce learning. * A section in each chapter on the role of the athletic trainer regarding the disease process and drug therapy. * New ancillary materials specifically for faculty that include PowerPoint slides and test bank questions. Principles of Pharmacology for Athletic Trainers, Second Edition will be the go-to resource to determine the best pharmacological treatment strategy and management by athletic trainers.

Author: Ying Xia
Publisher: Springer Science & Business Media
ISBN: 3642108571
Category : Medical
Languages : en
Pages : 480

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Book Description
Acupuncture therapy has been practiced in China and other Asian countries for more than two thousand years. Modern clinical research has confirmed the impressive therapeutic effect of acupuncture on numerous human ailments, such as controlling pain, nausea, and vomiting. However, the biological mechanisms of acupuncture are still under debate. In Traditional Chinese Medicine (TCM), the mechanism of acupuncture therapy is explained by a meridian model. According to this model, acupuncture is believed to treat the diseased organs by modulating two conditions known as Yin and Yang, which represent all the opposite principles that people find in the universe, both inside and outside the human body. Yin and Yang complement each other, and are subjected to changes between each other. The balance of Yin and Yang is thought to be maintained by Qi, an energy substance flowing constantly through the meridian, a network connecting all the organs of the body. The illness, according to this theory, is the temporary dominance of one principle over the other, owing to the blockade of the Qi from flowing through the meridian under certain circumstance. The axiom of “No stagnation, No pain” in TCM summarizes this concept. Thus, the goal of acupuncture treatment is to restore the balance of Yin and Yang conditions in the diseased organ(s). This theory has been considered to be useful to guide this ancient therapy, such as carrying out diagnosis, deciding on the principle, and selecting the acupoints.

Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309450292
Category : Medical
Languages : en
Pages : 97

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Book Description
Multimodal therapy approaches that combine interventions aimed at different aspects of disease are emerging as potentialâ€"and perhaps essentialâ€"ways to enhance clinical outcomes for patients with psychiatric and neurological disorders. In order to examine the general principles underlying multimodal therapies and to explore challenges, potential barriers, and opportunities for their development, the National Academies of Sciences, Engineering, and Medicine convened a workshop in June 2016. Participants explored scientific, clinical, regulatory, and reimbursement issues related to multimodal approaches and potential opportunities to enhance clinical outcomes for individuals with nervous system disorders. This publication summarizes the presentations and discussions from the workshop.