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Targeted Learning

Targeted Learning PDF Author: Mark J. van der Laan
Publisher: Springer Science & Business Media
ISBN: 1441997822
Category : Mathematics
Languages : en
Pages : 628

Book Description
The statistics profession is at a unique point in history. The need for valid statistical tools is greater than ever; data sets are massive, often measuring hundreds of thousands of measurements for a single subject. The field is ready to move towards clear objective benchmarks under which tools can be evaluated. Targeted learning allows (1) the full generalization and utilization of cross-validation as an estimator selection tool so that the subjective choices made by humans are now made by the machine, and (2) targeting the fitting of the probability distribution of the data toward the target parameter representing the scientific question of interest. This book is aimed at both statisticians and applied researchers interested in causal inference and general effect estimation for observational and experimental data. Part I is an accessible introduction to super learning and the targeted maximum likelihood estimator, including related concepts necessary to understand and apply these methods. Parts II-IX handle complex data structures and topics applied researchers will immediately recognize from their own research, including time-to-event outcomes, direct and indirect effects, positivity violations, case-control studies, censored data, longitudinal data, and genomic studies.

Targeted Learning

Targeted Learning PDF Author: Mark J. van der Laan
Publisher: Springer Science & Business Media
ISBN: 1441997822
Category : Mathematics
Languages : en
Pages : 628

Book Description
The statistics profession is at a unique point in history. The need for valid statistical tools is greater than ever; data sets are massive, often measuring hundreds of thousands of measurements for a single subject. The field is ready to move towards clear objective benchmarks under which tools can be evaluated. Targeted learning allows (1) the full generalization and utilization of cross-validation as an estimator selection tool so that the subjective choices made by humans are now made by the machine, and (2) targeting the fitting of the probability distribution of the data toward the target parameter representing the scientific question of interest. This book is aimed at both statisticians and applied researchers interested in causal inference and general effect estimation for observational and experimental data. Part I is an accessible introduction to super learning and the targeted maximum likelihood estimator, including related concepts necessary to understand and apply these methods. Parts II-IX handle complex data structures and topics applied researchers will immediately recognize from their own research, including time-to-event outcomes, direct and indirect effects, positivity violations, case-control studies, censored data, longitudinal data, and genomic studies.

Targeted Learning in Data Science

Targeted Learning in Data Science PDF Author: Mark J. van der Laan
Publisher: Springer
ISBN: 3319653040
Category : Mathematics
Languages : en
Pages : 640

Book Description
This textbook for graduate students in statistics, data science, and public health deals with the practical challenges that come with big, complex, and dynamic data. It presents a scientific roadmap to translate real-world data science applications into formal statistical estimation problems by using the general template of targeted maximum likelihood estimators. These targeted machine learning algorithms estimate quantities of interest while still providing valid inference. Targeted learning methods within data science area critical component for solving scientific problems in the modern age. The techniques can answer complex questions including optimal rules for assigning treatment based on longitudinal data with time-dependent confounding, as well as other estimands in dependent data structures, such as networks. Included in Targeted Learning in Data Science are demonstrations with soft ware packages and real data sets that present a case that targeted learning is crucial for the next generation of statisticians and data scientists. Th is book is a sequel to the first textbook on machine learning for causal inference, Targeted Learning, published in 2011. Mark van der Laan, PhD, is Jiann-Ping Hsu/Karl E. Peace Professor of Biostatistics and Statistics at UC Berkeley. His research interests include statistical methods in genomics, survival analysis, censored data, machine learning, semiparametric models, causal inference, and targeted learning. Dr. van der Laan received the 2004 Mortimer Spiegelman Award, the 2005 Van Dantzig Award, the 2005 COPSS Snedecor Award, the 2005 COPSS Presidential Award, and has graduated over 40 PhD students in biostatistics and statistics. Sherri Rose, PhD, is Associate Professor of Health Care Policy (Biostatistics) at Harvard Medical School. Her work is centered on developing and integrating innovative statistical approaches to advance human health. Dr. Rose’s methodological research focuses on nonparametric machine learning for causal inference and prediction. She co-leads the Health Policy Data Science Lab and currently serves as an associate editor for the Journal of the American Statistical Association and Biostatistics.

Profiling Target Learners for the Development of Effective Learning Strategies: Emerging Research and Opportunities

Profiling Target Learners for the Development of Effective Learning Strategies: Emerging Research and Opportunities PDF Author: Hai-Jew, Shalin
Publisher: IGI Global
ISBN: 1799815757
Category : Education
Languages : en
Pages : 183

Book Description
Since the early days of formalized large-scale testing, there have been efforts to understand learners in order to provide better aligned learning opportunities and accommodations. What has been less explored has been how prospective and current target learners are profiled as target groups to adapt the learning to them, both statically (such as in pre-learning biographical profiling) and dynamically (on-the-fly as they interact with learning contents in online learning systems). This work takes more of a micro-scale and meso-scale approach, and these often involve both formal and informal means and creative teaching-and-learning accommodations. Profiling Target Learners for the Development of Effective Learning Strategies: Emerging Research and Opportunities is a critical scholarly resource that focuses on the practice of profiling prospective and current target learners through manual and computational means in order to better meet and improve their online and offline learning needs, as well as how those profiles influence the design, development, and provision of learning experiences. Featuring a wide range of topics such as diversity, curriculum design, and online learning, this book is ideal for educators, curriculum developers, instructional designers, principals, educational software developers, administrators, policymakers, academicians, researchers, and students.

Culturally Responsive Teaching and The Brain

Culturally Responsive Teaching and The Brain PDF Author: Zaretta Hammond
Publisher: Corwin Press
ISBN: 1483308022
Category : Education
Languages : en
Pages : 311

Book Description
A bold, brain-based teaching approach to culturally responsive instruction To close the achievement gap, diverse classrooms need a proven framework for optimizing student engagement. Culturally responsive instruction has shown promise, but many teachers have struggled with its implementation—until now. In this book, Zaretta Hammond draws on cutting-edge neuroscience research to offer an innovative approach for designing and implementing brain-compatible culturally responsive instruction. The book includes: Information on how one’s culture programs the brain to process data and affects learning relationships Ten “key moves” to build students’ learner operating systems and prepare them to become independent learners Prompts for action and valuable self-reflection

Deep Learning for Radar and Communications Automatic Target Recognition

Deep Learning for Radar and Communications Automatic Target Recognition PDF Author: Uttam K. Majumder
Publisher: Artech House
ISBN: 1630816396
Category : Technology & Engineering
Languages : en
Pages : 290

Book Description
This authoritative resource presents a comprehensive illustration of modern Artificial Intelligence / Machine Learning (AI/ML) technology for radio frequency (RF) data exploitation. It identifies technical challenges, benefits, and directions of deep learning (DL) based object classification using radar data, including synthetic aperture radar (SAR) and high range resolution (HRR) radar. The performance of AI/ML algorithms is provided from an overview of machine learning (ML) theory that includes history, background primer, and examples. Radar data issues of collection, application, and examples for SAR/HRR data and communication signals analysis are discussed. In addition, this book presents practical considerations of deploying such techniques, including performance evaluation, energy-efficient computing, and the future unresolved issues.

Secondary Analysis of Electronic Health Records

Secondary Analysis of Electronic Health Records PDF Author: MIT Critical Data
Publisher: Springer
ISBN: 3319437429
Category : Medical
Languages : en
Pages : 427

Book Description
This book trains the next generation of scientists representing different disciplines to leverage the data generated during routine patient care. It formulates a more complete lexicon of evidence-based recommendations and support shared, ethical decision making by doctors with their patients. Diagnostic and therapeutic technologies continue to evolve rapidly, and both individual practitioners and clinical teams face increasingly complex ethical decisions. Unfortunately, the current state of medical knowledge does not provide the guidance to make the majority of clinical decisions on the basis of evidence. The present research infrastructure is inefficient and frequently produces unreliable results that cannot be replicated. Even randomized controlled trials (RCTs), the traditional gold standards of the research reliability hierarchy, are not without limitations. They can be costly, labor intensive, and slow, and can return results that are seldom generalizable to every patient population. Furthermore, many pertinent but unresolved clinical and medical systems issues do not seem to have attracted the interest of the research enterprise, which has come to focus instead on cellular and molecular investigations and single-agent (e.g., a drug or device) effects. For clinicians, the end result is a bit of a “data desert” when it comes to making decisions. The new research infrastructure proposed in this book will help the medical profession to make ethically sound and well informed decisions for their patients.

Machine Learning and Medical Imaging

Machine Learning and Medical Imaging PDF Author: Guorong Wu
Publisher: Academic Press
ISBN: 0128041145
Category : Technology & Engineering
Languages : en
Pages : 512

Book Description
Machine Learning and Medical Imaging presents state-of- the-art machine learning methods in medical image analysis. It first summarizes cutting-edge machine learning algorithms in medical imaging, including not only classical probabilistic modeling and learning methods, but also recent breakthroughs in deep learning, sparse representation/coding, and big data hashing. In the second part leading research groups around the world present a wide spectrum of machine learning methods with application to different medical imaging modalities, clinical domains, and organs. The biomedical imaging modalities include ultrasound, magnetic resonance imaging (MRI), computed tomography (CT), histology, and microscopy images. The targeted organs span the lung, liver, brain, and prostate, while there is also a treatment of examining genetic associations. Machine Learning and Medical Imaging is an ideal reference for medical imaging researchers, industry scientists and engineers, advanced undergraduate and graduate students, and clinicians. Demonstrates the application of cutting-edge machine learning techniques to medical imaging problems Covers an array of medical imaging applications including computer assisted diagnosis, image guided radiation therapy, landmark detection, imaging genomics, and brain connectomics Features self-contained chapters with a thorough literature review Assesses the development of future machine learning techniques and the further application of existing techniques

Moving Target

Moving Target PDF Author: Christina Diaz Gonzalez
Publisher: Scholastic Inc.
ISBN: 0545773202
Category : Juvenile Fiction
Languages : en
Pages : 217

Book Description
In this exciting and action-packed adventure by an award-winning author, a young girl discovers her secret ancient bloodline. The fate of her family, and the world, may rest in her hands . . . Cassie Arroyo, an American studying in Rome, has her world ripped apart when someone tries to kill her father, an art history professor at an Italian university. Is she their next target?Cassie sets out to uncover what is happening, only to learn that she is a member of an ancient bloodline that enables her to use the Spear of Destiny--a legendary object that can alter the future. Now running from a secret organization intent on killing those from her bloodline, Cassie must--with the help of some friends--decipher the clues that will lead her to the Spear.Christina Diaz Gonzalez has created a fast-paced thrill-ride of a book, rich with riddles and myth, that young readers will not want to put down.

An Introduction to Statistical Learning

An Introduction to Statistical Learning PDF Author: Gareth James
Publisher: Springer Nature
ISBN: 3031387473
Category : Mathematics
Languages : en
Pages : 617

Book Description
An Introduction to Statistical Learning provides an accessible overview of the field of statistical learning, an essential toolset for making sense of the vast and complex data sets that have emerged in fields ranging from biology to finance, marketing, and astrophysics in the past twenty years. This book presents some of the most important modeling and prediction techniques, along with relevant applications. Topics include linear regression, classification, resampling methods, shrinkage approaches, tree-based methods, support vector machines, clustering, deep learning, survival analysis, multiple testing, and more. Color graphics and real-world examples are used to illustrate the methods presented. This book is targeted at statisticians and non-statisticians alike, who wish to use cutting-edge statistical learning techniques to analyze their data. Four of the authors co-wrote An Introduction to Statistical Learning, With Applications in R (ISLR), which has become a mainstay of undergraduate and graduate classrooms worldwide, as well as an important reference book for data scientists. One of the keys to its success was that each chapter contains a tutorial on implementing the analyses and methods presented in the R scientific computing environment. However, in recent years Python has become a popular language for data science, and there has been increasing demand for a Python-based alternative to ISLR. Hence, this book (ISLP) covers the same materials as ISLR but with labs implemented in Python. These labs will be useful both for Python novices, as well as experienced users.

Learning in the Fast Lane

Learning in the Fast Lane PDF Author: Suzy Pepper Rollins
Publisher: ASCD
ISBN: 1416618716
Category : Education
Languages : en
Pages : 187

Book Description
Too often, students who fail a grade or a course receive remediation that ends up widening rather than closing achievement gaps. According to veteran classroom teacher and educational consultant Suzy Pepper Rollins, the true answer to supporting struggling students lies in acceleration. In Learning in the Fast Lane, she lays out a plan of action that teachers can use to immediately move underperforming students in the right direction and differentiate instruction for all learners—even those who excel academically. This essential guide identifies eight high-impact, research-based instructional approaches that will help you * Make standards and learning goals explicit to students. * Increase students' vocabulary—a key to their academic success. * Build students' motivation and self-efficacy so that they become active, optimistic participants in class. * Provide rich, timely feedback that enables students to improve when it counts. * Address skill and knowledge gaps within the context of new learning. Students deserve no less than the most effective strategies available. These hands-on, ready-to-implement practices will enable you to provide all students with compelling, rigorous, and engaging learning experiences.