Molecular Biology of The Cell PDF Download

Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0

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Author: Thomas Lejeune
Publisher: Nova Biomedical
ISBN: 9781608764013
Category : Medical
Languages : en
Pages : 545

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Book Description
Spermatozoa is the basic human male germ cell. This gametocyte plays an important role in fertilisation. In the past five years, new improvements in diagnosis have allowed us to assess male fertility potential with a new perspective studying with demonstrated role in sperm physiology. Furthermore, it is demonstrated that infertile men have high levels of sperm DNA damages and a small percentage of spermatozoa from fertile men also possess detectable levels of DNA damage. This book examines several of the factors that may be involved in sperm chromatin and DNA anomalies, including intra and extra testicular factors. Furthermore, sperm capacitation is a complex physiological process that involves biochemical, biophysical, molecular and metabolic modifications of all sperm domains. Some important events related to the capacitation process of sperm is examined as well. The biological role of the proteasome during sperm capacitation and the acrosome reaction and its relationship with protein phosphorylation and dephosphorylation during these processes is explored as well. Other chapters in this book highlight the pivotal role of transmission electron microscopy (TEM) analysis in the diagnosis of human sperm pathologies, the barrier methods currently available to men for regulating their fertility, a discussion of the current understanding of gene transfer to the testis, a new perspectives for the study of mycoplasmal and chlamydial infections of human spermatozoa and a discussion of the present current knowledge on the mechanisms, molecules and cell signalling involved in sperm activating ability.

Author: Nicholas Pound
Publisher: Taylor & Francis
ISBN: 9780387280363
Category : Health & Fitness
Languages : en
Pages : 322

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Book Description
This volume presents the intricate ways in which sperm compete to fertilize eggs and how this has prompted reinterpretations of breeding behavior from a biological perspective. Sperm Competition in Humans: Classic and Contemporary Readings provides a theoretical framework for the study of sperm competition and also discusses the roles of females and the relationships between paternal care in sperm competition. The chapters focus on everything from evolutionary biology to taxonomic development.

Author: R.R. Baker
Publisher: Springer
ISBN: 0412454300
Category : Science
Languages : en
Pages : 354

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Book Description
Behavioural ecologists and evolutionary biologists have long been interested in the biological implications of sperm from different males competing for fertilization of the egg in the female tract. This book discusses these implications for human sexual behaviour and human infertility problems.

Author: Patrick Fénichel
Publisher: John Libbey Eurotext
ISBN: 9782742000944
Category : Medical
Languages : en
Pages : 518

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Book Description
This valuable reference work provides a synthesis of the latest knowledge about the acrosomatic reaction of human sperm. The acrosomatic reaction, which is a fundamental step in the process of fertilisation, is examined on both the fundamental and clinical levels. Three very recent aspects are also dealt with: what happens to the acrosome during intracytoplasmic microinjections, the usefulness of screening spermatozoa that have completed their acrosomatic reaction, and the development of contraception by a vaccine that targets one of the proteins of the acrosome. International Symposium, Collioure, France, September 1995.

Author: Tomer Avidor-Reiss
Publisher: Frontiers Media SA
ISBN: 2889637476
Category :
Languages : en
Pages : 290

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Author: Thinus F. Kruger
Publisher: CRC Press
ISBN: 9781842142776
Category : Medical
Languages : en
Pages : 86

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Book Description
Sperm morphology evaluation by strict criteria is the gold-standard used by IVF and andrology units around the world. It is based on an approach to sperm morphology evaluation that utilizes optimal preparation methods, evaluation procedures, and criteria for a morphological normal spermatozoon based on biological evidence. Featuring fresh perspectives from the founders of the Tygerberg strict criteria, Atlas of Human Sperm Morphology Evaluation provides state-of-the-art information on crucial aspects of male factor infertility. The atlas consists of an introductory teaching manual that gives readers the ability to train and test their diagnostic capabilities and enables laboratories to implement quality control measures. Together with a team of internationally renowned experts in the field of human reproduction, the editors explore every avenue you need to know to successfully evaluate and manage male factor infertility. An accompanying interactive CD-ROM training program, STRICT 1-2-3® is available from the editors. STRICT 1-2-3® has been developed alongside the atlas to provide not only a complete theoretical background on sperm morphology, but also self-training facilities. Laboratory directors and technicians will now be able to set up their own internal quality control program for sperm morphology evaluation.

Author: World Health Organisation
Publisher: Cambridge University Press
ISBN: 9780521645997
Category : Medical
Languages : en
Pages : 150

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Book Description
The definitive and essential source of reference for all laboratories involved in the analysis of human semen.

Author: Elisabetta Baldi
Publisher: Springer Science & Business Media
ISBN: 1461477832
Category : Medical
Languages : en
Pages : 195

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Book Description
There are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. The purpose of this book is to provide a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.

Author: Rosaria Meccariello
Publisher: BoD – Books on Demand
ISBN: 1789231701
Category : Medical
Languages : en
Pages : 251

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Book Description
Spermatozoa, the haploid male gametes, are highly specialized cells capable to fertilize eggs in order to produce diploid zygote. The biogenesis of spermatozoa requires finely modulated occurrence of mitotic, meiotic, and differentiation events. Hence, the production of high-quality spermatozoa impacts fertilization with outcomes on the health of the offspring. This book provides a comprehensive overview on the biogenesis, maturation, functions and activities of spermatozoa in both physiological conditions and infertility. Particular attention has been addressed to the impact of environment on sperm quality and to the appropriate selection of high-quality spermatozoa for in vitro fertilization. Taken together, this book targets a wide audience of basic and clinical scientists, teachers and students, and offers a better understanding of spermatozoa health and disease.