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Bone Research in Biomechanics

Bone Research in Biomechanics PDF Author: G. Lowet
Publisher: IOS Press
ISBN: 9789051993271
Category : Biomechanics
Languages : en
Pages : 234

Book Description
This book focuses on the structure of bone, and its consequences for the mechanical behaviour of the bone structure. The first part of this book focuses on the development of models to predict the adaptation of bone due to changes on the mechanical loading situation (such as provoked by an implant). But far more important than the computer power presently available, the incorporation of knowledge on the biological processes have led to new kinds of models. Next to the development of models itself, the issue of model validation though comparison with clinical data is a main issue addressed in the papers of this symposium. The second part, dealing with the relationship between bone architecture and competence of bone, focuses on the morphology of trabecular bone structure. This work is mainly carried out in the context of research on osteoporosis, and look for the relation between bone structure and fracture risk. The last part is devoted to ultrasound research in bone biomechanics. Several methods have been described for the in vitro and in vivo measurement of ultrasound velocity and attenuation, both on cortical and on trabecular bone. The reader will not only discover the state-of-the-art when reading though this book. This book can give a taste of the fascinating perspectives the research in bone biomechanics still have to offer, even after more than 100 years.

Bone Research in Biomechanics

Bone Research in Biomechanics PDF Author: G. Lowet
Publisher: IOS Press
ISBN: 9789051993271
Category : Biomechanics
Languages : en
Pages : 234

Book Description
This book focuses on the structure of bone, and its consequences for the mechanical behaviour of the bone structure. The first part of this book focuses on the development of models to predict the adaptation of bone due to changes on the mechanical loading situation (such as provoked by an implant). But far more important than the computer power presently available, the incorporation of knowledge on the biological processes have led to new kinds of models. Next to the development of models itself, the issue of model validation though comparison with clinical data is a main issue addressed in the papers of this symposium. The second part, dealing with the relationship between bone architecture and competence of bone, focuses on the morphology of trabecular bone structure. This work is mainly carried out in the context of research on osteoporosis, and look for the relation between bone structure and fracture risk. The last part is devoted to ultrasound research in bone biomechanics. Several methods have been described for the in vitro and in vivo measurement of ultrasound velocity and attenuation, both on cortical and on trabecular bone. The reader will not only discover the state-of-the-art when reading though this book. This book can give a taste of the fascinating perspectives the research in bone biomechanics still have to offer, even after more than 100 years.

Skeletal Aging and Osteoporosis

Skeletal Aging and Osteoporosis PDF Author: Matthew J. Silva
Publisher: Springer Science & Business Media
ISBN: 3642180531
Category : Technology & Engineering
Languages : en
Pages : 261

Book Description
The focus of this book is on mechanical aspects of skeletal fragility related to aging and osteoporosis. Topics include: Age-related changes in trabecular structure and strength; age-related changes in cortical material properties; age-related changes in whole-bone structure; predicting bone strength and fracture risk using image-based methods and finite element analysis; animal models of osteoporosis and aging; age-related changes in skeletal mechano responsiveness; exercise and physical interventions for osteoporosis.

Trabecular and Cortical Bone

Trabecular and Cortical Bone PDF Author: Varsha Subramanium
Publisher: Nova Science Publishers
ISBN: 9781628087666
Category : Bone
Languages : en
Pages : 0

Book Description
In this book, the authors present topical research in the study of the morphology, biomechanics and clinical implications of trabecular and cortical bone. Topics discussed include trabecular bone biomechanics and morphology; cortical bone as an enduring depot of bone-seeking contaminants and the evaluation of cortical bone resportion rate on the basis of a contaminant (90SR) measurement in humans; evaluation of apparent stress and strain at fracture of human trabecular bone under quasi-static compression load using micro-CT finite elements simulation; application of computational modelling to predict the effect of exercise on whole bone strength; advancements in cortical bone imaging; morphology of the pelvis (acetabulum) and femur; the release kinetics of bone morphogenetic proteins from demineralised cortical bone grafts; and preservation of cortical bone in oral and maxillofacial surgery procedures.

Multiscale Biomechanics

Multiscale Biomechanics PDF Author: Jean-Francois Ganghoffer
Publisher: Elsevier
ISBN: 0081021151
Category : Medical
Languages : en
Pages : 582

Book Description
Multiscale Biomechanics provides new insights on multiscale static and dynamic behavior of both soft and hard biological tissues, including bone, the intervertebral disk, biological membranes and tendons. The physiological aspects of bones and biological membranes are introduced, along with micromechanical models used to compute mechanical response. A modern account of continuum mechanics of growth and remodeling, generalized continuum models to capture internal lengths scales, and dedicated homogenization methods are provided to help the reader with the necessary theoretical foundations. Topics discussed include multiscale methods for fibrous media based on discrete homogenization, generalized continua constitutive models for bone, and a presentation of recent theoretical and numerical advances. In addition, a refresher on continuum mechanics and more advanced background related to differential geometry, configurational mechanics, mechanics of growth, thermodynamics of open systems and homogenization methods is given in separate chapters. Numerical aspects are treated in detail, and simulations are presented to illustrate models. This book is intended for graduate students and researchers in biomechanics interested in the latest research developments, as well as those who wish to gain insight into the field of biomechanics. Provides a clear exposition of multiscale methods for fibrous media based on discrete homogenization and the consideration of generalized continua constitutive models for bone Presents recent theoretical and numerical advances for bone remodeling and growth Includes the necessary theoretical background that is exposed in a clear and self-contained manner Covers continuum mechanics and more advanced background related to differential geometry, configurational mechanics, mechanics of growth, thermodynamics of open systems and homogenization methods

Mechanical Testing of Bone and the Bone-Implant Interface

Mechanical Testing of Bone and the Bone-Implant Interface PDF Author: Yuehuei H. An
Publisher: CRC Press
ISBN: 1420073567
Category : Medical
Languages : en
Pages : 648

Book Description
The mechanical properties of whole bones, bone tissue, and the bone-implant interfaces are as important as their morphological and structural aspects. Mechanical Testing of Bone and the Bone-Implant Interface helps you assess these properties by explaining how to do mechanical testing of bone and the bone-implant interface for bone-related research

Bone Cell Biomechanics, Mechanobiology and Bone Diseases

Bone Cell Biomechanics, Mechanobiology and Bone Diseases PDF Author: Airong Qian
Publisher: Elsevier
ISBN: 0323994849
Category : Reference
Languages : en
Pages : 422

Book Description
Bone Cell Biomechanics, Mechanobiology and Bone Diseases provides a comprehensive overview of recent knowledge and advances of bone cell biomechanics and related bone diseases, highlighting the cellular basis for bone responding to mechanical stimuli. The book not only provides a general overview of bone cell biology, but also the most recent advances of bone cell biomechanics, mechanobiology, the relationship between bone cell biomechanics and bone diseases, as well as the underlying mechanism. This will be useful in understanding the role of mechanobiology in bone health and bone diseases, as well for investigating novel strategies for diagnosis and therapy of bone diseases. Cells covered in the book include osteocyte, BM-MSC, osteoblast, osteoclast and chondrocyte. Cone diseases covered are osteoporosis, scoliosis and osteoarthritis. This comprehensive reference is written for researchers, scientists, clinicians and students. Presents a comprehensive introduction of current knowledge and recent advances of bone cell biomechanics Introduces new technologies for bone cell research Discusses the bone cell mechanotransduction, mechanism and bone diseases

Clinical Biomechanics and Related Research

Clinical Biomechanics and Related Research PDF Author: Yasusuke Hirasawa
Publisher: Springer Science & Business Media
ISBN: 4431668594
Category : Medical
Languages : en
Pages : 422

Book Description
Clinical biomechanics is a rapidly changing field with an increasingly wide appeal. While the core subjects of biomechanics remain the behavior of bones, joints, ligaments, and muscles, this book focuses on more clinical aspects such as artificial joints, tissue transplantations, and the effects of disease on biomechanical properties. Also featured are special studies of the hand, spine, vascular system, and the analysis of three-dimensional motion. Based on the 20th Annual Meeting of the Japanese Society for Clinical Biomechanics and Related Research, this book provides an overview of the subject as well as describing many exciting new concepts and innovative methods for analyzing biomechanical systems. It should appeal across a wide spectrum of professions, proving indispensable to everyone from orthopedic surgeons to engineers with an interest in biology.

Skeletal Research: An Experimental Approach

Skeletal Research: An Experimental Approach PDF Author: David J. Simmons
Publisher: Elsevier
ISBN: 0323141595
Category : Science
Languages : en
Pages : 630

Book Description
Skeletal Research, An Experimental Approach discusses experimental studies on bone cell and tissue biochemistry, biomechanics, isolation, and methods of analysis. Divided into four parts encompassing 21 chapters, this book describes the advantages and limitations of approaches and options available for bone laboratories. The opening part of this book describes the isolation, characterization, and methods of analysis of bone and cartilage cells and their organ cultures. This description is followed by discussions on the intermediary metabolism of growth and articular cartilage; the isolation of plasma membranes from calcified connective tissues; and the aspects of lipidology as it applies to calcified tissue. The third part of this book focuses on the chemical, histochemical, and pathophysiological studies of bone as tissue. This text includes significant chapters on bone’s biomechanics and bioelectricity; bone mineral composition; collagen biochemistry; calcium metabolism; and blood flow. Studies on bone and cartilage as circadian systems in rats and mice, emphasizing the importance of this aspect of experimental design, are covered in the concluding part of this book. This text is an ideal resource to experienced researchers and young investigators who wish to expand their technical knowledge on bone research.

Basic Orthopaedic Biomechanics & Mechano-biology

Basic Orthopaedic Biomechanics & Mechano-biology PDF Author: Van C. Mow
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781739337
Category : Medical
Languages : en
Pages : 746

Book Description
Biomaterials / Ahmed El-Ghannam and Paul Ducheyne -- Biomechanics of the spine / Ian A. F. Stokes and James C. Iatridis -- Biomechanics of fracture fixation and fracture healing / Lutz E. Claes and Keita Ito -- Biomechanics and preclinical testing of artificial joints: the hip / Rik Huiskes and Jan Stolk -- Biomechanics of total knee replacement designs / Peter S. Walker.

Fundamental Biomechanics in Bone Tissue Engineering

Fundamental Biomechanics in Bone Tissue Engineering PDF Author: Xiaodu Wang
Publisher: Morgan & Claypool Publishers
ISBN: 1608451690
Category : Technology & Engineering
Languages : en
Pages : 216

Book Description
Bone repair presents a unique challenge to tissue engineering strategies because bone defects often occur at sites that withstand significant mechanical loading. Thus, the design and fabrication of bone tissue engineering products often require both sufficient mechanical competence and adequate architecture that promotes osteogenesis. To help reconcile these opposing needs, this book provides basic knowledge on both the biomechanics of bone and the biomechanics of scaffolds currently employed in bone tissue engineering. The intent of this information is to assist tissue engineers not only in design and fabrication of bone tissue engineering products, but also in the evaluation of such products and outcomes.