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Decellularized Extracellular Matrix

Decellularized Extracellular Matrix PDF Author: Takashi Hoshiba
Publisher: Royal Society of Chemistry
ISBN: 1788014677
Category : Science
Languages : en
Pages : 368

Book Description
Using this book, the reader will gain a good foundation to the field complemented with a broad overview of characterisation, microfabrication and applications.

Decellularized Extracellular Matrix

Decellularized Extracellular Matrix PDF Author: Takashi Hoshiba
Publisher: Royal Society of Chemistry
ISBN: 1788014677
Category : Science
Languages : en
Pages : 368

Book Description
Using this book, the reader will gain a good foundation to the field complemented with a broad overview of characterisation, microfabrication and applications.

Decellularized Scaffolds and Organogenesis

Decellularized Scaffolds and Organogenesis PDF Author: Kursad Turksen
Publisher: Humana Press
ISBN: 9781493976553
Category : Science
Languages : en
Pages :

Book Description
This practical, hands-on volume examines the use of decellularized tissues and organs as biologically-active scaffolds by providing numerous approaches from experts in the field. While knowledge of how to grow and differentiate cells in culture has dramatically improved over time, the book addresses the challenges of how to instruct particular cells of interest to recognize and respond to their environment so as to proliferate, differentiate, and function for restoration of original tissue and organ form and function. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, Decellularized Scaffolds and Organogenesis: Methods and Protocols share novel approaches and insights that will provide new opportunities for those already in the field or moving to enter the field.

Musculoskeletal Tissue Regeneration

Musculoskeletal Tissue Regeneration PDF Author: William S. Pietrzak
Publisher: Springer Science & Business Media
ISBN: 1597452394
Category : Medical
Languages : en
Pages : 649

Book Description
The repair of musculoskeletal tissue is a vital concern of all surgical specialties, orthopedics and related disciplines. Written by recognized experts, this book aims to provide both basic and advanced knowledge of the newer methodologies being developed and introduced to the clinical arena. A valuable resource for researchers, developers, and clinicians, the book presents a foundation to propel the technology and integration of the current state of knowledge into the 21st century.

Engineering Materials for Stem Cell Regeneration

Engineering Materials for Stem Cell Regeneration PDF Author: Faheem A. Sheikh
Publisher: Springer Nature
ISBN: 9811644209
Category : Science
Languages : en
Pages : 709

Book Description
This book reviews the interface of stem cell biology and biomaterials for regenerative medicine. It presents the applications of biomaterials to support stem cell growth and regeneration. The book discusses the stem cell interactions’ with nanofiber, gradient biomaterial, polymer- and ceramic biomaterials, integrating top-down and bottom-up approaches, adhesive properties of stem cells on materials, cell-laden hydrogels, micro-and nanospheres, de-cellularization techniques, and use of porous scaffolds. Further, this book provides a basic introduction to the fabrication techniques for creating various biomaterials that can be used for stem cell differentiation. It also elucidates the properties of stem cells, their characteristic features, tissue culture technology, properties of pluripotency, osteogenesis, and biomaterial interaction with de-cellularized organs, cell lineage in vivo and in vitro, gene expression, embryonic development, and cell differentiation. Further, the book reviews the latest applications of bio-instructive scaffold for supporting stem cell differentiation and tissue regeneration. The book also presents stem cell for dental, alveolar bone and cardiac regeneration. Lastly, it introduces engineered stem cells for delivering small molecule therapeutics and their potential biomedical applications.

Organ Printing

Organ Printing PDF Author: Dong-Woo Cho
Publisher: Morgan & Claypool Publishers
ISBN: 1681741431
Category : Technology & Engineering
Languages : en
Pages : 99

Book Description
This book introduces various 3D printing systems, biomaterials, and cells for organ printing. In view of the latest applications of several 3D printing systems, their advantages and disadvantages are also discussed. A basic understanding of the entire spectrum of organ printing provides pragmatic insight into the mechanisms, methods, and applications of this discipline. Organ printing is being applied in the tissue engineering field with the purpose of developing tissue/organ constructs for the regeneration of both hard (bone, cartilage, osteochondral) and soft tissues (heart). There are other potential application areas including tissue/organ models, disease/cancer models, and models for physiology and pathology, where in vitro 3D multicellular structures developed by organ printing are valuable.

Cardiovascular Regenerative Medicine

Cardiovascular Regenerative Medicine PDF Author: Vahid Serpooshan
Publisher: Springer
ISBN: 3030200477
Category : Medical
Languages : en
Pages : 233

Book Description
This book is a comprehensive and up-to-date resource on the use of regenerative medicine for the treatment of cardiovascular disease. It provides a much-needed review of the rapid development and evolution of bio-fabrication techniques to engineer cardiovascular tissues as well as their use in clinical settings. The book incorporates recent advances in the biology, biomaterial design, and manufacturing of bioengineered cardiovascular tissue with their clinical applications to bridge the basic sciences to current and future cardiovascular treatment. The book begins with an examination of state-of-the-art cellular, biomaterial, and macromolecular technologies for the repair and regeneration of diseased heart tissue. It discusses advances in nanotechnology and bioengineering of cardiac microtissues using acoustic assembly. Subsequent chapters explore the clinical applications and translational potential of current technologies such as cardiac patch-based treatments, cell-based regenerative therapies, and injectable hydrogels. The book examines how these methodologies are used to treat a variety of cardiovascular diseases including myocardial infarction, congenital heart disease, and ischemic heart injuries. Finally, the volume concludes with a summary of the most prominent challenges and perspectives on the field of cardiovascular tissue engineering and clinical cardiovascular regenerative medicine. Cardiovascular Regenerative Medicine is an essential resource for physicians, residents, fellows, and medical students in cardiology and cardiovascular regeneration as well as clinical and basic researchers in bioengineering, nanomaterial and technology, and cardiovascular biology.

Decellularization Methods of Tissue and Whole Organ in Tissue Engineering

Decellularization Methods of Tissue and Whole Organ in Tissue Engineering PDF Author: Abdol-Mohammad Kajbafzadeh
Publisher: Springer Nature
ISBN: 3030827356
Category : Medical
Languages : en
Pages : 266

Book Description
This contributed volume is the first of a series that introduces safe, feasible, and practical decellularization and recellularization techniques for tissue and organ reconstruction. We have put special emphasis on the research areas most likely to develop well-engineered scaffolds for tissue and organ engineering, while presenting easily applicable bench-to-bedside approaches highlighting the latest technical innovations in the field. This book includes both a fundamental discussion for a broad understanding of the basis of tissue repair and substitution, as well as chapters written by world renowned specialists from 20 countries providing deeper discussions and analysis of related sub disciplines. Within these pages, the reader will find state-of-the-art protocols and current clinical challenges in cell and tissue biology, including accurate and comprehensive information on extracellular matrices, natural biomaterials, tissue dynamics, morphogenesis, stem cells, cellular fate progressions, cell and tissue properties for in-vitro and in-vivo applications. This comprehensive and carefully organized treatise provides a clear framework for graduate students and postdoctoral researchers new to the field, but also for researchers and practitioners looking to expand their knowledge on tissue and organ reconstruction.

Decellularized Materials

Decellularized Materials PDF Author: Xiaoming Li
Publisher: Springer Nature
ISBN: 9813369620
Category : Medical
Languages : en
Pages : 517

Book Description
This book will consist of 8 chapters, in which important issues regarding decellularized materials (DMs) will be discussed. This book will provide special knowledge of materials for the persons with biomedical background, and special biomedical knowledge for the persons with the background of materials, which will hopefully become a valuable informative read for the researchers and students of biomedical engineering major.

Extracellular Matrix for Tissue Engineering and Biomaterials

Extracellular Matrix for Tissue Engineering and Biomaterials PDF Author: Anna C. Berardi
Publisher: Springer
ISBN: 3319770233
Category : Science
Languages : en
Pages : 213

Book Description
This volume provides a state-of-art-report on the new methodologies in tissue engineering and developments in the biomaterials field based on the extracellular matrix-relevant discovery. Extracellular Matrix for Tissue Engineering and Biomaterials opens with an overview of the latest extracellular matrix research and in Part I, focuses on its biology and its role on cell behavior and cell fate relevant for the design of biomimetic surfaces. Part II details issues regarding the strategies currently applied in the research of biologically inspired materials and material systems for the replacement, repair and regeneration of tissues and organs. Part III presents the latest development methods applying knowledge from biology towards nanotechnology, to promote the restoration of the functionality of a living tissue. The book ranges from fundamental biology associated with tissue regeneration for the development of biomimetic approaches to controlling tissue formation, cell function, differentiation and angiogenesis using factors involved in normal tissue development and function. With the breadth and depth of the coverage of this topic, this book will serve as a valuable reference for anyone working in tissue engineering or biomaterials – from scientists, chemists and biologists through physicists, bioengineers and clinicians.

Extracellular Matrix in Development

Extracellular Matrix in Development PDF Author: Douglas W. DeSimone
Publisher: Springer Science & Business Media
ISBN: 3642359353
Category : Science
Languages : en
Pages : 260

Book Description
Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix – secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.