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Large-scale Inference

Large-scale Inference PDF Author: Bradley Efron
Publisher:
ISBN: 9786612818745
Category : Bayesian statistical decision theory
Languages : en
Pages : 263

Book Description
We live in a new age for statistical inference, where modern scientific technology such as microarrays and fMRI machines routinely produce thousands and sometimes millions of parallel data sets, each with its own estimation or testing problem. Doing thousands of problems at once is more than repeated application of classical methods. Taking an empirical Bayes approach, Bradley Efron, inventor of the bootstrap, shows how information accrues across problems in a way that combines Bayesian and frequentist ideas. Estimation, testing, and prediction blend in this framework, producing opportunities for new methodologies of increased power. New difficulties also arise, easily leading to flawed inferences. This book takes a careful look at both the promise and pitfalls of large-scale statistical inference, with particular attention to false discovery rates, the most successful of the new statistical techniques. Emphasis is on the inferential ideas underlying technical developments, illustrated using a large number of real examples.

Large-scale Inference

Large-scale Inference PDF Author: Bradley Efron
Publisher:
ISBN: 9786612818745
Category : Bayesian statistical decision theory
Languages : en
Pages : 263

Book Description
We live in a new age for statistical inference, where modern scientific technology such as microarrays and fMRI machines routinely produce thousands and sometimes millions of parallel data sets, each with its own estimation or testing problem. Doing thousands of problems at once is more than repeated application of classical methods. Taking an empirical Bayes approach, Bradley Efron, inventor of the bootstrap, shows how information accrues across problems in a way that combines Bayesian and frequentist ideas. Estimation, testing, and prediction blend in this framework, producing opportunities for new methodologies of increased power. New difficulties also arise, easily leading to flawed inferences. This book takes a careful look at both the promise and pitfalls of large-scale statistical inference, with particular attention to false discovery rates, the most successful of the new statistical techniques. Emphasis is on the inferential ideas underlying technical developments, illustrated using a large number of real examples.

Large-Scale Inference

Large-Scale Inference PDF Author: Bradley Efron
Publisher: Cambridge University Press
ISBN: 1139492136
Category : Mathematics
Languages : en
Pages :

Book Description
We live in a new age for statistical inference, where modern scientific technology such as microarrays and fMRI machines routinely produce thousands and sometimes millions of parallel data sets, each with its own estimation or testing problem. Doing thousands of problems at once is more than repeated application of classical methods. Taking an empirical Bayes approach, Bradley Efron, inventor of the bootstrap, shows how information accrues across problems in a way that combines Bayesian and frequentist ideas. Estimation, testing and prediction blend in this framework, producing opportunities for new methodologies of increased power. New difficulties also arise, easily leading to flawed inferences. This book takes a careful look at both the promise and pitfalls of large-scale statistical inference, with particular attention to false discovery rates, the most successful of the new statistical techniques. Emphasis is on the inferential ideas underlying technical developments, illustrated using a large number of real examples.

Computer Age Statistical Inference

Computer Age Statistical Inference PDF Author: Bradley Efron
Publisher: Cambridge University Press
ISBN: 1108107958
Category : Mathematics
Languages : en
Pages : 496

Book Description
The twenty-first century has seen a breathtaking expansion of statistical methodology, both in scope and in influence. 'Big data', 'data science', and 'machine learning' have become familiar terms in the news, as statistical methods are brought to bear upon the enormous data sets of modern science and commerce. How did we get here? And where are we going? This book takes us on an exhilarating journey through the revolution in data analysis following the introduction of electronic computation in the 1950s. Beginning with classical inferential theories - Bayesian, frequentist, Fisherian - individual chapters take up a series of influential topics: survival analysis, logistic regression, empirical Bayes, the jackknife and bootstrap, random forests, neural networks, Markov chain Monte Carlo, inference after model selection, and dozens more. The distinctly modern approach integrates methodology and algorithms with statistical inference. The book ends with speculation on the future direction of statistics and data science.

Computer Age Statistical Inference, Student Edition

Computer Age Statistical Inference, Student Edition PDF Author: Bradley Efron
Publisher: Cambridge University Press
ISBN: 1108915876
Category : Mathematics
Languages : en
Pages : 514

Book Description
The twenty-first century has seen a breathtaking expansion of statistical methodology, both in scope and influence. 'Data science' and 'machine learning' have become familiar terms in the news, as statistical methods are brought to bear upon the enormous data sets of modern science and commerce. How did we get here? And where are we going? How does it all fit together? Now in paperback and fortified with exercises, this book delivers a concentrated course in modern statistical thinking. Beginning with classical inferential theories - Bayesian, frequentist, Fisherian - individual chapters take up a series of influential topics: survival analysis, logistic regression, empirical Bayes, the jackknife and bootstrap, random forests, neural networks, Markov Chain Monte Carlo, inference after model selection, and dozens more. The distinctly modern approach integrates methodology and algorithms with statistical inference. Each chapter ends with class-tested exercises, and the book concludes with speculation on the future direction of statistics and data science.

Graphical Models, Exponential Families, and Variational Inference

Graphical Models, Exponential Families, and Variational Inference PDF Author: Martin J. Wainwright
Publisher: Now Publishers Inc
ISBN: 1601981848
Category : Computers
Languages : en
Pages : 324

Book Description
The core of this paper is a general set of variational principles for the problems of computing marginal probabilities and modes, applicable to multivariate statistical models in the exponential family.

Information Theory, Inference and Learning Algorithms

Information Theory, Inference and Learning Algorithms PDF Author: David J. C. MacKay
Publisher: Cambridge University Press
ISBN: 9780521642989
Category : Computers
Languages : en
Pages : 694

Book Description
Table of contents

Simultaneous Statistical Inference

Simultaneous Statistical Inference PDF Author: Thorsten Dickhaus
Publisher: Springer Science & Business Media
ISBN: 3642451829
Category : Science
Languages : en
Pages : 180

Book Description
This monograph will provide an in-depth mathematical treatment of modern multiple test procedures controlling the false discovery rate (FDR) and related error measures, particularly addressing applications to fields such as genetics, proteomics, neuroscience and general biology. The book will also include a detailed description how to implement these methods in practice. Moreover new developments focusing on non-standard assumptions are also included, especially multiple tests for discrete data. The book primarily addresses researchers and practitioners but will also be beneficial for graduate students.

Statistical Inference as Severe Testing

Statistical Inference as Severe Testing PDF Author: Deborah G. Mayo
Publisher: Cambridge University Press
ISBN: 1108563309
Category : Mathematics
Languages : en
Pages : 503

Book Description
Mounting failures of replication in social and biological sciences give a new urgency to critically appraising proposed reforms. This book pulls back the cover on disagreements between experts charged with restoring integrity to science. It denies two pervasive views of the role of probability in inference: to assign degrees of belief, and to control error rates in a long run. If statistical consumers are unaware of assumptions behind rival evidence reforms, they can't scrutinize the consequences that affect them (in personalized medicine, psychology, etc.). The book sets sail with a simple tool: if little has been done to rule out flaws in inferring a claim, then it has not passed a severe test. Many methods advocated by data experts do not stand up to severe scrutiny and are in tension with successful strategies for blocking or accounting for cherry picking and selective reporting. Through a series of excursions and exhibits, the philosophy and history of inductive inference come alive. Philosophical tools are put to work to solve problems about science and pseudoscience, induction and falsification.

Foundational Principles for Large Scale Inference

Foundational Principles for Large Scale Inference PDF Author: Alfred Olivier Hero
Publisher:
ISBN:
Category : Correlation (Statistics)
Languages : en
Pages : 37

Book Description


Statistical Inference in Science

Statistical Inference in Science PDF Author: D.A. Sprott
Publisher: Springer Science & Business Media
ISBN: 0387950192
Category : Mathematics
Languages : en
Pages : 254

Book Description
A treatment of the problems of inference associated with experiments in science, with the emphasis on techniques for dividing the sample information into various parts, such that the diverse problems of inference that arise from repeatable experiments may be addressed. A particularly valuable feature is the large number of practical examples, many of which use data taken from experiments published in various scientific journals. This book evolved from the authors own courses on statistical inference, and assumes an introductory course in probability, including the calculation and manipulation of probability functions and density functions, transformation of variables and the use of Jacobians. While this is a suitable text book for advanced undergraduate, Masters, and Ph.D. statistics students, it may also be used as a reference book.