Mathematical Modeling for the Life Sciences PDF Download

Author: Jacques Istas
Publisher: Springer Science & Business Media
ISBN: 354027877X
Category : Mathematics
Languages : en
Pages : 168

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Book Description
Provides a wide range of mathematical models currently used in the life sciences Each model is thoroughly explained and illustrated by example Includes three appendices to allow for independent reading

Author: Alan Garfinkel
Publisher: Springer
ISBN: 3319597310
Category : Mathematics
Languages : en
Pages : 445

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Book Description
This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly. Complex feedback relations and counter-intuitive responses are common in nature; this book develops the quantitative skills needed to explore these interactions. Differential equations are the natural mathematical tool for quantifying change, and are the driving force throughout this book. The use of Euler’s method makes nonlinear examples tractable and accessible to a broad spectrum of early-stage undergraduates, thus providing a practical alternative to the procedural approach of a traditional Calculus curriculum. Tools are developed within numerous, relevant examples, with an emphasis on the construction, evaluation, and interpretation of mathematical models throughout. Encountering these concepts in context, students learn not only quantitative techniques, but how to bridge between biological and mathematical ways of thinking. Examples range broadly, exploring the dynamics of neurons and the immune system, through to population dynamics and the Google PageRank algorithm. Each scenario relies only on an interest in the natural world; no biological expertise is assumed of student or instructor. Building on a single prerequisite of Precalculus, the book suits a two-quarter sequence for first or second year undergraduates, and meets the mathematical requirements of medical school entry. The later material provides opportunities for more advanced students in both mathematics and life sciences to revisit theoretical knowledge in a rich, real-world framework. In all cases, the focus is clear: how does the math help us understand the science?

Author: Paul Doucet
Publisher: Prentice Hall
ISBN: 9780135620182
Category : Biomathematics.
Languages : en
Pages : 490

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Book Description
Combining mathematics, biology, statistics and computer applications, this text applies mathematical methods to the solution of biological and related problems. It demonstrates how to formulate mathematical models of dynamic processes and how to study their behaviour analytically and numerically.

Author: Brian P. Ingalls
Publisher: MIT Press
ISBN: 0262545829
Category : Science
Languages : en
Pages : 423

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Book Description
An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.

Author: Giovanni Naldi
Publisher: Springer Science & Business Media
ISBN: 0817649468
Category : Mathematics
Languages : en
Pages : 437

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Book Description
Using examples from finance and modern warfare to the flocking of birds and the swarming of bacteria, the collected research in this volume demonstrates the common methodological approaches and tools for modeling and simulating collective behavior. The topics presented point toward new and challenging frontiers of applied mathematics, making the volume a useful reference text for applied mathematicians, physicists, biologists, and economists involved in the modeling of socio-economic systems.

Author: Frank C. Hoppensteadt
Publisher: Springer Science & Business Media
ISBN: 1475741316
Category : Mathematics
Languages : en
Pages : 257

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Book Description
The aim of this book is to introduce the subject of mathematical modeling in the life sciences. It is intended for students of mathematics, the physical sciences, and engineering who are curious about biology. Additionally, it will be useful to students of the life sciences and medicine who are unsatisfied with mere description and who seek an understanding of biological mechanism and dynamics through the use of mathematics. The book will be particularly useful to premedical students, because it will introduce them not only to a collection of mathematical methods but also to an assortment of phenomena involving genetics, epidemics, and the physiology of the heart, lung, and kidney. Because of its introductory character, mathematical prerequisites are kept to a minimum; they involve only what is usually covered in the first semester of a calculus sequence. The authors have drawn on their extensive experience as modelers to select examples which are simple enough to be understood at this elementary level and yet realistic enough to capture the essence of significant biological phenomena drawn from the areas of population dynamics and physiology. Because the models presented are realistic, the book can serve not only as an introduction to mathematical methods but also as a mathematical introduction to the biological material itself. For the student, who enjoys mathematics, such an introduction will be far more stimulating and satisfying than the purely descriptive approach that is traditional in the biological sciences.

Author: Michael Olinick
Publisher: John Wiley & Sons
ISBN: 1118642694
Category : Mathematics
Languages : en
Pages : 594

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Book Description
Olinick’s Mathematical Models in the Social and Life Sciences concentrates not on physical models, but on models found in biology, social science, and daily life. This text concentrates on a relatively small number of models to allow students to study them critically and in depth, and balances practice and theory in its approach. Each chapter concluded with suggested projects that encourage students to build their own models, and space is set aside for historical and biographical notes about the development of mathematical models.

Author: James L. Cornette
Publisher: American Mathematical Soc.
ISBN: 1470451425
Category : Calculus
Languages : en
Pages : 713

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Book Description
Calculus for the Life Sciences is an entire reimagining of the standard calculus sequence with the needs of life science students as the fundamental organizing principle. Those needs, according to the National Academy of Science, include: the mathematical concepts of change, modeling, equilibria and stability, structure of a system, interactions among components, data and measurement, visualization, and algorithms. This book addresses, in a deep and significant way, every concept on that list. The book begins with a primer on modeling in the biological realm and biological modeling is the theme and frame for the entire book. The authors build models of bacterial growth, light penetration through a column of water, and dynamics of a colony of mold in the first few pages. In each case there is actual data that needs fitting. In the case of the mold colony that data is a set of photographs of the colony growing on a ruled sheet of graph paper and the students need to make their own approximations. Fundamental questions about the nature of mathematical modeling—trying to approximate a real-world phenomenon with an equation—are all laid out for the students to wrestle with. The authors have produced a beautifully written introduction to the uses of mathematics in the life sciences. The exposition is crystalline, the problems are overwhelmingly from biology and interesting and rich, and the emphasis on modeling is pervasive. An instructor's manual for this title is available electronically to those instructors who have adopted the textbook for classroom use. Please send email to [email protected] for more information. Online question content and interactive step-by-step tutorials are available for this title in WebAssign. WebAssign is a leading provider of online instructional tools for both faculty and students.

Author: Avner Friedman
Publisher: Springer
ISBN: 3319083147
Category : Mathematics
Languages : en
Pages : 154

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Book Description
This book on mathematical modeling of biological processes includes a wide selection of biological topics that demonstrate the power of mathematics and computational codes in setting up biological processes with a rigorous and predictive framework. Topics include: enzyme dynamics, spread of disease, harvesting bacteria, competition among live species, neuronal oscillations, transport of neurofilaments in axon, cancer and cancer therapy, and granulomas. Complete with a description of the biological background and biological question that requires the use of mathematics, this book is developed for graduate students and advanced undergraduate students with only basic knowledge of ordinary differential equations and partial differential equations; background in biology is not required. Students will gain knowledge on how to program with MATLAB without previous programming experience and how to use codes in order to test biological hypothesis.

Author: Glenn Ledder
Publisher: Springer Science & Business Media
ISBN: 1461472768
Category : Mathematics
Languages : en
Pages : 431

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Book Description
​ ​​ Mathematics for the Life Sciences provides present and future biologists with the mathematical concepts and tools needed to understand and use mathematical models and read advanced mathematical biology books. It presents mathematics in biological contexts, focusing on the central mathematical ideas, and providing detailed explanations. The author assumes no mathematics background beyond algebra and precalculus. Calculus is presented as a one-chapter primer that is suitable for readers who have not studied the subject before, as well as readers who have taken a calculus course and need a review. This primer is followed by a novel chapter on mathematical modeling that begins with discussions of biological data and the basic principles of modeling. The remainder of the chapter introduces the reader to topics in mechanistic modeling (deriving models from biological assumptions) and empirical modeling (using data to parameterize and select models). The modeling chapter contains a thorough treatment of key ideas and techniques that are often neglected in mathematics books. It also provides the reader with a sophisticated viewpoint and the essential background needed to make full use of the remainder of the book, which includes two chapters on probability and its applications to inferential statistics and three chapters on discrete and continuous dynamical systems. The biological content of the book is self-contained and includes many basic biology topics such as the genetic code, Mendelian genetics, population dynamics, predator-prey relationships, epidemiology, and immunology. The large number of problem sets include some drill problems along with a large number of case studies. The latter are divided into step-by-step problems and sorted into the appropriate section, allowing readers to gradually develop complete investigations from understanding the biological assumptions to a complete analysis.