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Skin 3-D Models and Cosmetics Toxicity

Skin 3-D Models and Cosmetics Toxicity PDF Author: Aditya Bhushan Pant
Publisher: Springer Nature
ISBN: 9819928044
Category : Medical
Languages : en
Pages : 266

Book Description
Efforts are being made by research organizations and cosmetic industries worldwide to develop more precise and targeted 3D models that mimic humans for testing cosmetic and personal health care product ingredients, following a complete ban on animal testing. This book includes several subtopics dedicated to the progress made, challenges faced, roadblocks encountered, and future prospects in the development and validation of 3D models for testing these products. The book consist of an editorial and 14 themed chapters that will showcase the significant progress made so far, challenges encountered, and future prospects in the development of 3D reconstruct models.

Skin 3-D Models and Cosmetics Toxicity

Skin 3-D Models and Cosmetics Toxicity PDF Author: Aditya Bhushan Pant
Publisher: Springer Nature
ISBN: 9819928044
Category : Medical
Languages : en
Pages : 266

Book Description
Efforts are being made by research organizations and cosmetic industries worldwide to develop more precise and targeted 3D models that mimic humans for testing cosmetic and personal health care product ingredients, following a complete ban on animal testing. This book includes several subtopics dedicated to the progress made, challenges faced, roadblocks encountered, and future prospects in the development and validation of 3D models for testing these products. The book consist of an editorial and 14 themed chapters that will showcase the significant progress made so far, challenges encountered, and future prospects in the development of 3D reconstruct models.

Skin 3-D Models and Cosmetics Toxicity

Skin 3-D Models and Cosmetics Toxicity PDF Author: Aditya Bhushan Pant
Publisher: Springer
ISBN: 9789819928033
Category : Medical
Languages : en
Pages : 0

Book Description
Efforts are being made by research organizations and cosmetic industries worldwide to develop more precise and targeted 3D models that mimic humans for testing cosmetic and personal health care product ingredients, following a complete ban on animal testing. This book includes several subtopics dedicated to the progress made, challenges faced, roadblocks encountered, and future prospects in the development and validation of 3D models for testing these products. The book consist of an editorial and 14 themed chapters that will showcase the significant progress made so far, challenges encountered, and future prospects in the development of 3D reconstruct models.

Skin Tissue Models

Skin Tissue Models PDF Author: Alexandra P. Marques
Publisher: Academic Press
ISBN: 0128110007
Category : Science
Languages : en
Pages : 472

Book Description
Skin Tissue Models provides a translational link for biomedical researchers on the interdisciplinary approaches to skin regeneration. As the skin is the largest organ in the body, engineered substitutes have critical medical application to patients with disease and injury – from burn wounds and surgical scars, to vitiligo, psoriasis and even plastic surgery. This volume offers readers preliminary description of the normal structure and function of mammalian skin, exposure to clinical problems and disease, coverage of potential therapeutic molecules and testing, skin substitutes, models as study platforms of skin biology and emerging technologies. The editors have created a table of contents which frames the relevance of skin tissue models for researchers as platforms to study skin biology and therapeutic approaches for different skin diseases, for clinicians as tissue substitutes, and for cosmetic and pharmaceutical industries as alternative test substrates that can replace animal models. Offers descriptions of the normal structure/function of mammalian skin, exposure to clinical problems, and more Presents coverage of skin diseases (cancer, genodermatoses, vitiligo and psoriasis) that extends to clinical requirements and skin diseases in vitro models Addresses legal requirements and ethical concerns in drugs and cosmetics in vitro testing Edited and authored by internationally renowned group of researchers, presenting the broadest coverage possible

Principles and Practice of Skin Toxicology

Principles and Practice of Skin Toxicology PDF Author: Robert Chilcott
Publisher: John Wiley & Sons
ISBN: 0470773081
Category : Science
Languages : en
Pages : 392

Book Description
Written by authorities in the field, this book provides a “bottom up” approach to studying skin toxicology. Principles and Practice of Skin Toxicology clearly outlines basic concepts, cites historical and modern references and contains a dictionary for easy reference. The inclusion of global legislation and regulatory aspects on the topic makes this a comprehensive review for every practitioner, clinical researcher in industry and academia, and MSc and PhD student of toxicology. Different sections cover skin structure and function, principles and measurement of skin absorption, clinical aspects of dermal toxicity and in vitro alternatives. A section on regulatory and legislative aspects includes case studies from the UK that fulfill European Union and US FDA requirements. A glossary provides definitions of technical terms, and the chapters contain an introduction, learning boxes and summary section for ease of use. Includes a chapter on drug delivery through the skin. Addresses risk assessment: a key area for the interpretation of skin absorption data that is rarely covered.

New Technologies for Toxicity Testing

New Technologies for Toxicity Testing PDF Author: Michael Balls
Publisher: Springer Science & Business Media
ISBN: 1461430550
Category : Medical
Languages : en
Pages : 258

Book Description
The central theme running through this volume on New Technologies for Toxicity Testing is the development and application of advanced techniques for cell and tissue culture, as well as new markers and endpoints of toxicity, as alternatives to the traditional paradigm of relying on data from laboratory animal tests to undertake labelling and risk assessment. Of course, many of the techniques and methods described in this volume are in the early stages of development, and much work will be needed to ensure their further improvement, optimisation and validation. However, we are confident that this will be achieved and that, just as with the in vitro assays that were validated and granted regulatory acceptance over the last decade, these, and many other new, advanced methods, will likewise become part of the toxicologist’s improved toolbox for coping with increasingly stringent and numerous regulatory requirements and test chemicals, while placing less reliance on traditional testing paradigms.

Nanotechnology for the Preparation of Cosmetics using Plant-Based Extracts

Nanotechnology for the Preparation of Cosmetics using Plant-Based Extracts PDF Author: Siti Hamidah Mohd Setapar
Publisher: Elsevier
ISBN: 012822939X
Category : Technology & Engineering
Languages : en
Pages : 410

Book Description
Cosmetic manufacturers use nanoscale size ingredients to provide better UV protection, deeper skin penetration, long-lasting effects, increased color and finish quality. This approach enables the forming of nanoscale cosmetic ingredients, which can possess active components readily absorbed into the skin, repair damage easily, and promote improved product outcomes. Nanotechnology for the Preparation of Cosmetics using Plant-Based Extracts explores the various applications of nanotechnology in the cosmetic industry. Techniques for the development of cosmetic are a topic of increasing interest with widespread opportunities for potential applications in a broad range of industrial applications. The book covers a variety of techniques and processes, focusing on its potential applications in the field of skincare and makeup cosmetics. The book will cover not only conventional processes but also innovative and efficient techniques for the preparation of cosmetics exhibiting unique applications in the field. Nanotechnology for the Preparation of Cosmetics using Plant-Based Extracts is an important reference source for materials scientists, engineers and pharmaceutical scientists who want to learn more about the use of cosmetics prepared through nanotechnology to achieve the materials characteristics and enhancements in the mechanism and properties of makeup and skincare. Presents techniques for the design and manufacture of high-performance skincare products using nanotechnology Demonstrates systematic approaches and investigations for the design, synthesis, characterization and applications of various plant-based extracts in order to make them effective ingredients for cosmetics creation Assesses the major challenges of using plant-based materials in the manufacture of cosmetic products

Biofabrication and 3D Tissue Modeling

Biofabrication and 3D Tissue Modeling PDF Author: Dong-Woo Cho
Publisher: Royal Society of Chemistry
ISBN: 1788011988
Category : Technology & Engineering
Languages : en
Pages : 369

Book Description
3D tissue modelling is an emerging field used for the investigation of disease mechanisms and drug development. The two key drivers of this upsurge in research lie in its potential to offer a way to reduce animal testing with respect to biotoxicity analysis, preferably on physiology recapitulated human tissues and, additionally, it provides an alternative approach to regenerative medicine. Integrating physics, chemistry, materials science, and stem cell and biomedical engineering, this book provides a complete foundation to this exciting, and interdisciplinary field. Beginning with the basic principles of 3D tissue modelling, the reader will find expert reviews on key fabrication technologies and processes, including microfluidics, microfabrication technology such as 3D bioprinting, and programming approaches to emulating human tissue complexity. The next stage introduces the reader to a range of materials used for 3D tissue modelling, from synthetic to natural materials, as well as the emerging field of tissue derived decellularized extracellular matrix (dECM). A whole host of critical applications are covered, with several chapters dedicated to hard and soft tissues, as well as focused reviews on the respiratory and central nervous system. Finally, the development of in vitro tissue models to screen drugs and study progression and etiologies of diseases, with particular attention paid to cancer, can be found.

Proceedings of 15th Euro-Global Summit on Toxicology and Applied Pharmacology 2018

Proceedings of 15th Euro-Global Summit on Toxicology and Applied Pharmacology 2018 PDF Author: ConferenceSeries
Publisher: ConferenceSeries
ISBN:
Category :
Languages : en
Pages : 131

Book Description
July 02-04, 2018 Berlin, Germany Key topics : Toxicology, Clinical & Medical Toxicology, Food and Nutritional Toxicology, Environmental Toxicology, Industrial & Occupational Toxicology, Systems Toxicology, Immunotoxicology, Chemical Carcinogenesis, Methods for Toxicity Testing, Risk Assessment, Toxicity Testing Markets, Emerging Toxicology Concepts, Molecular and Biochemical Toxicology, Reproductive and Developmental Toxicology, Genetic Toxicology, Drug Toxicology, Product Development Toxicology, Pharmacology, Developmental Pharmacology, Applied Pharmacology,

Organotypic Models in Drug Development

Organotypic Models in Drug Development PDF Author: Monika Schäfer-Korting
Publisher: Springer Nature
ISBN: 3030700631
Category : Medical
Languages : en
Pages : 325

Book Description
This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major interest and funding in the EU and the US has increased over the last years. Moreover, so-called 3R (reduce, replace, refine animal experiments) centres have been established worldwide.

Nanocosmetics

Nanocosmetics PDF Author: Arun Nanda
Publisher: Elsevier
ISBN: 0128222867
Category : Technology & Engineering
Languages : en
Pages : 520

Book Description
Nanotechnology is key to the design and manufacture of the new generation of cosmetics. Nanotechnology can enhance the performance and properties of cosmetics, including colour, transparency, solubility, texture, and durability. Sunscreen products, such as UV nano-filters, nano-TiO2 and nano-ZnO particles, can offer an advantage over their traditional counterparts due to their broad UV-protection and non-cutaneous side effects. For perfumes, nano-droplets can be found in cosmetic products including Eau de Toilette and Eau de Parfum. Nanomaterials can also be used in cosmetics as transdermal drug delivery systems. By using smart nanocontainers, active compounds such as vitamins, antioxidants, nutrients, and anti-inflammatory, anti-infective agents, can be delivered effectively. These smart nanocontainers are typically related with the smart releasing property for their embedded active substances. These smart releases could be obtained by using the smart coatings as their outer nano-shells. These nano-shells could prevent the direct contact between these active agents and the adjacent local environments. Nanocosmetics: Fundamentals, Applications and Toxicity explores the formulation design concepts and emerging applications of nanocosmetics. The book also focuses on the mitigation or prevention of their potential nanotoxicity, potential global regulatory challenges, and the technical challenges of mass implementation. It is an important reference source for materials scientists and pharmaceutical scientists looking to further their understanding of how nanotechnology is being used for the new generation of cosmetics. Outlines the major fabrication and formulation design concepts of nanoscale products for cosmetic applications Explores how nanomaterials can safely be used for various applications in cosmetic products Assesses the major challenges of using nanomaterials for cosmetic applications on a large scale