Stochastic Modelling of Reaction-Diffusion Processes PDF Download

Author: Radek Erban
Publisher: Cambridge University Press
ISBN: 1108498124
Category : Mathematics
Languages : en
Pages : 321

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Book Description
Practical introduction for advanced undergraduate or beginning graduate students of applied mathematics, developed at the University of Oxford.

Author: Radek Erban
Publisher: Cambridge University Press
ISBN: 1108572995
Category : Mathematics
Languages : en
Pages : 322

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Book Description
This practical introduction to stochastic reaction-diffusion modelling is based on courses taught at the University of Oxford. The authors discuss the essence of mathematical methods which appear (under different names) in a number of interdisciplinary scientific fields bridging mathematics and computations with biology and chemistry. The book can be used both for self-study and as a supporting text for advanced undergraduate or beginning graduate-level courses in applied mathematics. New mathematical approaches are explained using simple examples of biological models, which range in size from simulations of small biomolecules to groups of animals. The book starts with stochastic modelling of chemical reactions, introducing stochastic simulation algorithms and mathematical methods for analysis of stochastic models. Different stochastic spatio-temporal models are then studied, including models of diffusion and stochastic reaction-diffusion modelling. The methods covered include molecular dynamics, Brownian dynamics, velocity jump processes and compartment-based (lattice-based) models.

Author: David Holcman
Publisher: Springer
ISBN: 3319626272
Category : Mathematics
Languages : en
Pages : 377

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Book Description
This book focuses on the modeling and mathematical analysis of stochastic dynamical systems along with their simulations. The collected chapters will review fundamental and current topics and approaches to dynamical systems in cellular biology. This text aims to develop improved mathematical and computational methods with which to study biological processes. At the scale of a single cell, stochasticity becomes important due to low copy numbers of biological molecules, such as mRNA and proteins that take part in biochemical reactions driving cellular processes. When trying to describe such biological processes, the traditional deterministic models are often inadequate, precisely because of these low copy numbers. This book presents stochastic models, which are necessary to account for small particle numbers and extrinsic noise sources. The complexity of these models depend upon whether the biochemical reactions are diffusion-limited or reaction-limited. In the former case, one needs to adopt the framework of stochastic reaction-diffusion models, while in the latter, one can describe the processes by adopting the framework of Markov jump processes and stochastic differential equations. Stochastic Processes, Multiscale Modeling, and Numerical Methods for Computational Cellular Biology will appeal to graduate students and researchers in the fields of applied mathematics, biophysics, and cellular biology.

Author: Stefanie Winkelmann
Publisher: Springer Nature
ISBN: 3030623874
Category : Mathematics
Languages : en
Pages : 284

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Book Description
The aim of this book is to provide a well-structured and coherent overview of existing mathematical modeling approaches for biochemical reaction systems, investigating relations between both the conventional models and several types of deterministic-stochastic hybrid model recombinations. Another main objective is to illustrate and compare diverse numerical simulation schemes and their computational effort. Unlike related works, this book presents a broad scope in its applications, from offering a detailed introduction to hybrid approaches for the case of multiple population scales to discussing the setting of time-scale separation resulting from widely varying firing rates of reaction channels. Additionally, it also addresses modeling approaches for non well-mixed reaction-diffusion dynamics, including deterministic and stochastic PDEs and spatiotemporal master equations. Finally, by translating and incorporating complex theory to a level accessible to non-mathematicians, this book effectively bridges the gap between mathematical research in computational biology and its practical use in biological, biochemical, and biomedical systems.

Author: Howard M. Taylor
Publisher: Academic Press
ISBN: 1483269272
Category : Mathematics
Languages : en
Pages : 410

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Book Description
An Introduction to Stochastic Modeling provides information pertinent to the standard concepts and methods of stochastic modeling. This book presents the rich diversity of applications of stochastic processes in the sciences. Organized into nine chapters, this book begins with an overview of diverse types of stochastic models, which predicts a set of possible outcomes weighed by their likelihoods or probabilities. This text then provides exercises in the applications of simple stochastic analysis to appropriate problems. Other chapters consider the study of general functions of independent, identically distributed, nonnegative random variables representing the successive intervals between renewals. This book discusses as well the numerous examples of Markov branching processes that arise naturally in various scientific disciplines. The final chapter deals with queueing models, which aid the design process by predicting system performance. This book is a valuable resource for students of engineering and management science. Engineers will also find this book useful.

Author: Paola Lecca
Publisher: Elsevier
ISBN: 1908818212
Category : Mathematics
Languages : en
Pages : 411

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Book Description
Stochastic kinetic methods are currently considered to be the most realistic and elegant means of representing and simulating the dynamics of biochemical and biological networks. Deterministic versus stochastic modelling in biochemistry and systems biology introduces and critically reviews the deterministic and stochastic foundations of biochemical kinetics, covering applied stochastic process theory for application in the field of modelling and simulation of biological processes at the molecular scale. Following an overview of deterministic chemical kinetics and the stochastic approach to biochemical kinetics, the book goes onto discuss the specifics of stochastic simulation algorithms, modelling in systems biology and the structure of biochemical models. Later chapters cover reaction-diffusion systems, and provide an analysis of the Kinfer and BlenX software systems. The final chapter looks at simulation of ecodynamics and food web dynamics. Introduces mathematical concepts and formalisms of deterministic and stochastic modelling through clear and simple examples Presents recently developed discrete stochastic formalisms for modelling biological systems and processes Describes and applies stochastic simulation algorithms to implement a stochastic formulation of biochemical and biological kinetics

Author: Kurt Jacobs
Publisher: Cambridge University Press
ISBN: 1139486799
Category : Science
Languages : en
Pages : 203

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Book Description
Stochastic processes are an essential part of numerous branches of physics, as well as in biology, chemistry, and finance. This textbook provides a solid understanding of stochastic processes and stochastic calculus in physics, without the need for measure theory. In avoiding measure theory, this textbook gives readers the tools necessary to use stochastic methods in research with a minimum of mathematical background. Coverage of the more exotic Levy processes is included, as is a concise account of numerical methods for simulating stochastic systems driven by Gaussian noise. The book concludes with a non-technical introduction to the concepts and jargon of measure-theoretic probability theory. With over 70 exercises, this textbook is an easily accessible introduction to stochastic processes and their applications, as well as methods for numerical simulation, for graduate students and researchers in physics.

Author: Jesús Ildefonso Díaz
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110647516
Category : Mathematics
Languages : en
Pages : 178

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Book Description
The series is devoted to the publication of high-level monographs which cover the whole spectrum of current nonlinear analysis and applications in various fields, such as optimization, control theory, systems theory, mechanics, engineering, and other sciences. One of its main objectives is to make available to the professional community expositions of results and foundations of methods that play an important role in both the theory and applications of nonlinear analysis. Contributions which are on the borderline of nonlinear analysis and related fields and which stimulate further research at the crossroads of these areas are particularly welcome. Editor-in-Chief J rgen Appell, W rzburg, Germany Honorary and Advisory Editors Catherine Bandle, Basel, Switzerland Alain Bensoussan, Richardson, Texas, USA Avner Friedman, Columbus, Ohio, USA Umberto Mosco, Worcester, Massachusetts, USA Louis Nirenberg, New York, USA Alfonso Vignoli, Rome, Italy Editorial Board Manuel del Pino, Bath, UK, and Santiago, Chile Mikio Kato, Nagano, Japan Wojciech Kryszewski, Toruń, Poland Vicenţiu D. Rădulescu, Krak w, Poland Simeon Reich, Haifa, Israel Please submit book proposals to J rgen Appell. Titles in planning include Lucio Damascelli and Filomena Pacella, Morse Index of Solutions of Nonlinear Elliptic Equations (2019) Tomasz W. Dlotko and Yejuan Wang, Critical Parabolic-Type Problems (2019) Rafael Ortega, Periodic Differential Equations in the Plane: A Topological Perspective (2019) Ireneo Peral Alonso and Fernando Soria, Elliptic and Parabolic Equations Involving the Hardy-Leray Potential (2020) Cyril Tintarev, Profile Decompositions and Cocompactness: Functional-Analytic Theory of Concentration Compactness (2020) Takashi Suzuki, Semilinear Elliptic Equations: Classical and Modern Theories (2021)

Author: Christiane Fuchs
Publisher: Springer Science & Business Media
ISBN: 3642259693
Category : Mathematics
Languages : en
Pages : 439

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Book Description
Diffusion processes are a promising instrument for realistically modelling the time-continuous evolution of phenomena not only in the natural sciences but also in finance and economics. Their mathematical theory, however, is challenging, and hence diffusion modelling is often carried out incorrectly, and the according statistical inference is considered almost exclusively by theoreticians. This book explains both topics in an illustrative way which also addresses practitioners. It provides a complete overview of the current state of research and presents important, novel insights. The theory is demonstrated using real data applications.

Author: Herold G. Dehling
Publisher: Elsevier
ISBN: 9780080548975
Category : Mathematics
Languages : en
Pages : 290

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Book Description
There is an ever increasing need for modelling complex processes reliably. Computational modelling techniques, such as CFD and MD may be used as tools to study specific systems, but their emergence has not decreased the need for generic, analytical process models. Multiphase and multicomponent systems, and high-intensity processes displaying a highly complex behaviour are becoming omnipresent in the processing industry. This book discusses an elegant, but little-known technique for formulating process models in process technology: stochastic process modelling. The technique is based on computing the probability distribution for a single particle's position in the process vessel, and/or the particle's properties, as a function of time, rather than - as is traditionally done - basing the model on the formulation and solution of differential conservation equations. Using this technique can greatly simplify the formulation of a model, and even make modelling possible for processes so complex that the traditional method is impracticable. Stochastic modelling has sporadically been used in various branches of process technology under various names and guises. This book gives, as the first, an overview of this work, and shows how these techniques are similar in nature, and make use of the same basic mathematical tools and techniques. The book also demonstrates how stochastic modelling may be implemented by describing example cases, and shows how a stochastic model may be formulated for a case, which cannot be described by formulating and solving differential balance equations. Introduction to stochastic process modelling as an alternative modelling technique Shows how stochastic modelling may be succesful where the traditional technique fails Overview of stochastic modelling in process technology in the research literature Illustration of the principle by a wide range of practical examples In-depth and self-contained discussions Points the way to both mathematical and technological research in a new, rewarding field