The 6 DS of Fecal Microbiota Transplantation PDF Download

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Publisher:
ISBN: 9781630917517
Category :
Languages : en
Pages :

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Author: J. ALLEGRETTI
Publisher: Slack
ISBN: 9781630917500
Category :
Languages : en
Pages : 200

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"A practical handbook for physicians, nurses, physician assistants, students, residents, and fellows, The 6 Ds of Fecal Microbiota Transplantation provides a clinical framework to understand and administer FMT as safely and effectively as possible. FMT has emerged as a promising treatment for Clostridioides difficile infection (CDI) and other clinical conditions linked to the microbiome. However, there is a need for educational resources for clinicians. This guide provides practical tools, clinical pearls, and answers to frequently asked questions on the treatment, as well as outlines a step-by-step checklist for administering FMT: Decision: Who is the right patient to receive FMT? Donor: How do you select and screen a donor for FMT? Discussion: What are the risks, benefits, and alternatives that need to be discussed with patients? Delivery: What is the best delivery method for FMT? Discharge and follow-up: What is the ideal post-FMT care? Discovery: What are the most promising emerging clinical applications for FMT?"--

Author: Jessica Allegretti
Publisher: CRC Press
ISBN: 1040138012
Category : Medical
Languages : en
Pages : 169

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A practical handbook on fecal microbiota transplantation (FMT) for physicians, nurses, physician assistants, students, residents, and fellows, The 6 Ds of Fecal Microbiota Transplantation: A Primer from Decision to Discharge and Beyond provides a clinical framework to understand and administer this treatment as safely and effectively as possible. FMT has emerged as a promising treatment for C. difficile infection (CDI), and there is a major need for educational resources on the topic. Drs. Jessica Allegretti, Zain Kassam, and their expert contributors are leaders in the field and have collectively cared for thousands of patients suffering from recurrent CDI who have benefitted from FMT. This guide provides practical tools, clinical pearls, and answers to frequently asked questions. Beginning with introductory information on the microbiome and exploring the history of FMT, The 6 Ds of Fecal Microbiota Transplantation outlines a step-by-step checklist for administering FMT: Decision: Who is the right CDI patient to receive FMT? What clinical questions should you ask patients in your FMT clinical assessment? Donor: How do you select and screen a donor for FMT? Discussion: What are the risks, benefits, and alternatives that need to be discussed with patients? Delivery: What is the best delivery method for FMT—colonoscopy, nasogastric tube, enema, or capsules? Discharge and follow-up: What is the ideal post-FMT care? How should you council patients following FMT? Discovery: What are the most promising emerging clinical applications for FMT? What is the evidence for FMT in obesity, autism, irritable bowel syndrome, inflammatory bowel disease, antibiotic resistant bacteria, and liver disease? Arming healthcare professionals with the ability to answer questions from patients regarding FMT and the microbiome, The 6 Ds of Fecal Microbiota Transplantationprovides a pragmatic guide for this exciting treatment.

Author: Martin H. Floch
Publisher: Academic Press
ISBN: 0128040629
Category : Medical
Languages : en
Pages : 442

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The Microbiota in Gastrointestinal Pathophysiology: Implications for Human Health, Prebiotics, Probiotics and Dysbiosis is a one-stop reference on the state-of-the-art research on gut microbial ecology in relation to human disease. This important resource starts with an overview of the normal microbiota of the gastrointestinal tract, including the esophagus, stomach, Ileum, and colon. The book then identifies what a healthy vs. unhealthy microbial community looks like, including methods of identification. Also included is insight into which features and contributions the microbiota make that are essential and useful to host physiology, as is information on how to promote appropriate mutualisms and prevent undesirable dysbioses. Through the power of synthesizing what is known by experienced researchers in the field, current gaps are closed, raising understanding of the role of the microbiome and allowing for further research. Explains how to modify the gut microbiota and how the current strategies used to do this produce their effects Explores the gut microbiota as a therapeutic target Provides the synthesis of existing data from both mainstream and non-mainstream sources through experienced researchers in the field Serves as a ‘one-stop’ shop for a topic that’s currently spread across a number of various journals

Author: Scott Lee
Publisher: Elsevier Health Sciences
ISBN: 0323835597
Category : Medical
Languages : en
Pages : 201

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Together with Consulting Editor, Dr. Alan Buchman, Dr. Scott Lee has put together a state-of-the-art issue of Gastroenterology Clinics devoted to Ulcerative Colitis (UC). He has selected expert authors to contribute clinical reviews that provide the latest clinical findings and recommendations. Articles are devoted to the following topics: Epidemiology and pathogenesis of UC; Making initial diagnosis of UC and ruling out other diseases that mimic UC; Assessing severity of disease; Initial medical treatment of UC; Treatment of UC with steroids; Biologic therapy in UC; Non-biologic immune suppression in UC; Microbiome and fecal transplant in UC; Health maintenance in UC, including bone density scan, vaccination recommendations, cancer screening; Women's issues and UC; Risk of colon cancer and recommended surveillance strategies in UC patients; Surgical management of UC, indications and outcomes from colectomy; and Management of J-pouches. Readers will come away with the latest clinical recommendations they need to improve outcomes in patients with UC.

Author: Yashi Nozawa
Publisher: Createspace Independent Publishing Platform
ISBN: 9781507834633
Category :
Languages : en
Pages : 92

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Infection with antibiotic-resistant microbes, often referred as "super-bugs," in hospitals can be a common problem. A conventional solution to the problem is to find a new antibiotic. This solution simply accelerates an arms race between microbes and pharmaceutical companies which try to develop an effective antibiotic. We should search for a completely new approach to the problem. This book might suggest an alternative approach for the superbug problem. It describes the tragic experience of a student nurse, Betty, who performed the world's first fecal transplant. It is not well known to the general public, but there are some diseases that infect mostly patients in hospitals. These diseases are often referred to as post-operative complications or a new infection, due to patients' weakened immune system. Pseudo membranous colitis (PM colitis) was one of such diseases, which predominantly affects patients after surgery of the digestive system. It had a high fatality rate, but there was no known effective treatment. An odd circumstance pushed Betty to perform the world's first fecal transplant and demonstrate its effectiveness. However, because of the stigma attached to feces, fellow medical staff ridiculed her to such a degree that she could not remain as a staff nurse. Later academic researchers identified the pathogen of PM colitis as Clostridium difficile (C. diff), and renamed the disease C-diff infection. Again although fecal transplant was an effective treatment for the disease, the mainstream establishment of the medical community ignored the treatment. When C. diff evolved an antibiotic-resistant strain, hundred-thousands of patients died in hospitals every year around the world. In the United States, bureaucratic hurdles prevented research of fecal transplant, despite such a high mortality rate. Eventually, the news of effectiveness of fecal transplant spread on the Internet and many patients started doing by themselves with help of friends and relatives because medical doctors were unwilling to perform such illegal treatment. In 2013, after more than fifty years from Betty's action, FDA finally and reluctantly allowed doctors to perform fecal transplant for limited cases of C-diff infection. FDA also renamed the procedure FMT (Fecal Microbiota Transplantation.) Meanwhile Betty suffered personal tragedy, but she finally retired and enjoyed her peaceful life knowing that the mainstream of the medical community accepted fecal transplant, even for limited cases. This book also comments on the FDA and NIH's role in new drug development, especially concerned about Ebola epidemic.

Author: Jeffrey Glasheen
Publisher: Elsevier Health Sciences
ISBN: 0323414532
Category : Medical
Languages : en
Pages :

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This online Clinics series provides evidence-based answers to clinical questions the practicing hospitalist faces daily. Now entering the fifth volume year of our growing online database, this issue edited by Jeff Glasheen and Mary Anderson, covers essential updates in the following topics: Vascular Access for Hospitalized Patients ,Mechanical and Noninvasive Ventilation,Isolation Precautions,Nephrolithiasis,Fecal Microbiota Transplant, Regional Anesthesia (Peripheral Nerve Blocks and Epidurals),Chemotherapy and Biologic/Targeted Therapies, Procedural Skills for the Hospitalist, Palliative Sedation, and Patient Experience.

Author: Jason Tetro
Publisher: DEStech Publications, Inc
ISBN: 1605951595
Category : Medical
Languages : en
Pages : 382

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Critical reference explains strategies of microbiome research in humansSummarizes the microbiome's effects on immunity, metabolism, genetics and psychologyEvaluates medical and nutritional therapies for modifying the microbiomeFor healthcare researchers, nutritionists, microbiologists, and medical professionals Written by a team of leading scientists, this book offers a concise technical reference covering human microbiome research and its ramifications for medicine and nutrition. The initial chapters furnish a scientific explanation of the microbiome in general and its ecology. The book then provides a detailed investigation of microbial populations as these pertain to physiology, metabolism and immunology. The final portions are devoted to exploration of the microbiome's effects on chronic and autoimmune diseases and include assessments of clinical therapies and nutritional interventions designed to alter the microbiome to mitigate chronic health conditions.

Author: Alessandro Fichera
Publisher: Springer
ISBN: 3319141813
Category : Medical
Languages : en
Pages : 306

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Crohn’s Disease: Basic Principles provides a comprehensive and state-of-the-art overview of the current diagnosis and treatment strategies for Crohn’s disease. Care of these patients and clinical conditions can be quite complex and often require a multidisciplinary approach. Sections of the book are based on the most current, evidenced-based resources and have been structured to review the etiology and diagnosis of Crohn’s disease, discuss advances in medical and surgical treatment, illustrate emerging technologies impacting the care of patients with Crohn’s disease, and examine functional and quality of life outcomes in this patient population. The text reviews our understanding of the influence of molecular and genetic factors in the development and pattern of Crohn’s disease. Current methods of diagnosis and strategies in the medical management of patients with Crohn’s disease are evaluated including the use of biologic agents. Resection and bowel sparing techniques for primary and recurrent disease as well as advances in endoscopy and laparoscopy are discussed in detail. In addition, factors influencing the quality of life of patients with Crohn’s disease are examined including nutrition, enterostomal care, fertility, and sexual function. Written by recognized experts in their field, Crohn’s Disease: Basic Principles highlights the integrated multidimensional aspect of caring for patients with Crohn’s disease and will be of great value to colon and rectal surgeons, general surgeons, gastroenterologists, internists, as well as fellows and upper level residents in training training.

Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 1681086387
Category : Science
Languages : en
Pages : 246

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Frontiers in Clinical Drug Research – Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents.Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. The fifth volume of this series features six reviews: - Integrated Approaches for Marine Actinomycete Biodiscovery - Therapeutic Use of Commensal Microbes: Fecal/Gut Microbiota Transplantation - Alternative Approaches to Antimicrobials - Nanoantibiotics: Recent Developments and Future - Cranberry Juice and Other Functional Foods in Urinary Tract Infections in Women: A Review of Actual Evidence and Main Challenges - Targeting Magnesium Homeostasis as Potential Anti-Infective Strategy Against Mycobacteria