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Author: American Association for Cancer Research Publisher: ISBN: Category : Languages : en Pages : 0
Book Description
Unprecedented progress in medical research is increasing our understanding of the collection of diseases we call cancer and is driving improvements in cancer prevention, early detection, diagnosis, and treatment. These advances are made possible by investments in NIH, NCI, FDA, and CDC by the U.S. federal government. As the first and largest professional organization in the world dedicated to preventing and curing all cancers, AACR continues to be a catalyst for scientific breakthroughs that save the lives of patients with cancer. AACR is committed to increasing public understanding of cancer and advocating for increased funding for medical research.The annual AACR Cancer Progress Report to Congress and the American public is a cornerstone of AACR's educational efforts. This thirteenth edition of the report highlights how research continues to extend and improve the lives of Americans, including the lives of the eight courageous individuals featured in the report and their family members who have shared their experiences with cancer. It also underscores how unwavering, bipartisan support from Congress, in the form of robust and sustained annual increases in funding for NIH, NCI, FDA, and CDC, is urgently needed.The remarkable progress being made against cancer is resulting in a steady reduction in cancer death rates, and a consistent rise in the number of people who live longer and fuller lives after a cancer diagnosis. In fact, the overall U.S. cancer death rate has fallen by 33 percent between 1991 and 2020, a reduction that translates into averting an estimated 3.8 million deaths from cancer. The reduction in overall cancer mortality is driven largely by the decline in the U.S. lung cancer death rate, the pace of which has accelerated in recent years because of reduction in smoking and advances in early detection and treatment. Additionally, the reduction in death rates for melanoma, colorectal cancer, prostate cancer, and female breast cancer has contributed to the progress against overall U.S. cancer mortality. Notably, among U.S. children and adolescents, overall cancer death rates have declined by 70 percent and 64 percent, respectively, over the past five decades.
Author: American Association for Cancer Research Publisher: ISBN: Category : Languages : en Pages : 0
Book Description
Unprecedented progress in medical research is increasing our understanding of the collection of diseases we call cancer and is driving improvements in cancer prevention, early detection, diagnosis, and treatment. These advances are made possible by investments in NIH, NCI, FDA, and CDC by the U.S. federal government. As the first and largest professional organization in the world dedicated to preventing and curing all cancers, AACR continues to be a catalyst for scientific breakthroughs that save the lives of patients with cancer. AACR is committed to increasing public understanding of cancer and advocating for increased funding for medical research.The annual AACR Cancer Progress Report to Congress and the American public is a cornerstone of AACR's educational efforts. This thirteenth edition of the report highlights how research continues to extend and improve the lives of Americans, including the lives of the eight courageous individuals featured in the report and their family members who have shared their experiences with cancer. It also underscores how unwavering, bipartisan support from Congress, in the form of robust and sustained annual increases in funding for NIH, NCI, FDA, and CDC, is urgently needed.The remarkable progress being made against cancer is resulting in a steady reduction in cancer death rates, and a consistent rise in the number of people who live longer and fuller lives after a cancer diagnosis. In fact, the overall U.S. cancer death rate has fallen by 33 percent between 1991 and 2020, a reduction that translates into averting an estimated 3.8 million deaths from cancer. The reduction in overall cancer mortality is driven largely by the decline in the U.S. lung cancer death rate, the pace of which has accelerated in recent years because of reduction in smoking and advances in early detection and treatment. Additionally, the reduction in death rates for melanoma, colorectal cancer, prostate cancer, and female breast cancer has contributed to the progress against overall U.S. cancer mortality. Notably, among U.S. children and adolescents, overall cancer death rates have declined by 70 percent and 64 percent, respectively, over the past five decades.
Author: American Association for Cancer Research Publisher: ISBN: Category : Languages : en Pages : 0
Book Description
Transformative research and technological innovations are driving unprecedented progress against the collection of diseases we call cancer. As the first and largest professional organization in the world dedicated to advancing all areas of cancer research and patient care, AACR has been and continues to be a catalyst for scientific breakthroughs that save and enhance the lives of cancer patients. It is also committed to increasing public understanding of cancer and advocating for increased federal funding for cancer research and related sciences. The annual AACR Cancer Progress Report to Congress and the American public is a cornerstone of AACR's educational efforts. This twelfth edition of the report highlights how research continues to extend and improve lives, including the lives of the five courageous individuals featured in the report and their family members who have shared their experiences with cancer. It also underscores how unwavering, bipartisan support from Congress, in the form of robust and sustained annual increases in funding for NIH, NCI, CDC, and FDA, is urgently needed if we are to realize our vision of eradicating cancer for all populations. The remarkable progress being made against cancer-in particular, improvements in reducing smoking rates and developments in early detection and treatment-is resulting in a steady fall in cancer death rates, and a consistent rise in the number of people who live longer after a cancer diagnosis. In fact, in the United States, the age-adjusted overall cancer death rate has been declining since the 1990s, with the reductions between 1991 and 2019 translating into nearly 3.5 million cancer deaths avoided. Additionally, the number of cancer survivors living in the United States has exceeded 18 million as of January 1, 2022. Unfortunately, certain U.S. populations, including racial and ethnic minorities and several other medically underserved groups, have not benefited equally from the advances against cancer. Complex factors referred to as social determinants of health have contributed to cancer health disparities in the United States. It is imperative that all stakeholders work together to eradicate the systemic and structural injustices that are current barriers.
Author: National Academies of Sciences, Engineering, and Medicine Publisher: National Academies Press ISBN: 0309457971 Category : Medical Languages : en Pages : 145
Book Description
Advances in cancer research have led to an improved understanding of the molecular mechanisms underpinning the development of cancer and how the immune system responds to cancer. This influx of research has led to an increasing number and variety of therapies in the drug development pipeline, including targeted therapies and associated biomarker tests that can select which patients are most likely to respond, and immunotherapies that harness the body's immune system to destroy cancer cells. Compared with standard chemotherapies, these new cancer therapies may demonstrate evidence of benefit and clearer distinctions between efficacy and toxicity at an earlier stage of development. However, there is a concern that the traditional processes for cancer drug development, evaluation, and regulatory approval could impede or delay the use of these promising cancer treatments in clinical practice. This has led to a number of effortsâ€"by patient advocates, the pharmaceutical industry, and the Food and Drug Administration (FDA)â€"to accelerate the review of promising new cancer therapies, especially for cancers that currently lack effective treatments. However, generating the necessary data to confirm safety and efficacy during expedited drug development programs can present a unique set of challenges and opportunities. To explore this new landscape in cancer drug development, the National Academies of Sciences, Engineering, and Medicine developed a workshop held in December 2016. This workshop convened cancer researchers, patient advocates, and representatives from industry, academia, and government to discuss challenges with traditional approaches to drug development, opportunities to improve the efficiency of drug development, and strategies to enhance the information available about a cancer therapy throughout its life cycle in order to improve its use in clinical practice. This publication summarizes the presentations and discussions from the workshop.
Author: Paul H. Sugarbaker Publisher: Springer Science & Business Media ISBN: 1461526043 Category : Medical Languages : en Pages : 326
Book Description
When one deals with cancer, the hepatobiliary malignancies present a chal lenge to the oncologists that can be characterized as a series of unsolved clinical and biological dilemmas. Liver metastases from colorectal and other gastrointestinal malignancies, hepatocellular carcinoma, cholangiocar cinoma, and gall bladder cancer present an array of problems but have two features in common. These are high morbidity and mortality with an overall poor result from treatment. Why is it that hepatobiliary cancer carries with it such a dismal prognosis? First of all, these diseases present, for the most part, in an advanced state. To this point in time the oncologist has had no help from early diagnosis or screening. Only the occasional patient followed by ultrasound or a tumor marker has the disease diagnosed in an asymptomatic state. By the time these diseases become symptomatic, curative treatment options have usually disappeared. Evolution has placed the liver in a protected position in order to avoid injury to the soft parenchyma. As with many other internal organs, the nerve supply is extremely limited. These two anatomic features result in a great lack of early warning signs of cancer.
Author: American Association for Cancer Research Publisher: ISBN: Category : Languages : en Pages :
Book Description
Launched in 2020, the AACR Cancer Disparities Progress Report 2020 to Congress and the American public is a cornerstone of the AACR's educational and advocacy efforts to achieve health equity. This second edition of the report highlights areas of recent progress in reducing cancer health disparities. It also emphasizes the vital need for continued transformative research and for increased collaborations if we are to ensure that advances against cancer benefit all patients, regardless of their race, ethnicity, age, sexual orientation, gender identity, socioeconomic status, or geographic location.
Author: Committee on Improving the Quality of Cancer Care: Addressing the Challenges of an Aging Population Publisher: National Academies Press ISBN: 9780309286602 Category : Medical Languages : en Pages : 0
Book Description
In the United States, approximately 14 million people have had cancer and more than 1.6 million new cases are diagnosed each year. However, more than a decade after the Institute of Medicine (IOM) first studied the quality of cancer care, the barriers to achieving excellent care for all cancer patients remain daunting. Care often is not patient-centered, many patients do not receive palliative care to manage their symptoms and side effects from treatment, and decisions about care often are not based on the latest scientific evidence. The cost of cancer care also is rising faster than many sectors of medicine--having increased to $125 billion in 2010 from $72 billion in 2004--and is projected to reach $173 billion by 2020. Rising costs are making cancer care less affordable for patients and their families and are creating disparities in patients' access to high-quality cancer care. There also are growing shortages of health professionals skilled in providing cancer care, and the number of adults age 65 and older--the group most susceptible to cancer--is expected to double by 2030, contributing to a 45 percent increase in the number of people developing cancer. The current care delivery system is poorly prepared to address the care needs of this population, which are complex due to altered physiology, functional and cognitive impairment, multiple coexisting diseases, increased side effects from treatment, and greater need for social support. Delivering High-Quality Cancer Care: Charting a New Course for a System in Crisis presents a conceptual framework for improving the quality of cancer care. This study proposes improvements to six interconnected components of care: (1) engaged patients; (2) an adequately staffed, trained, and coordinated workforce; (3) evidence-based care; (4) learning health care information technology (IT); (5) translation of evidence into clinical practice, quality measurement and performance improvement; and (6) accessible and affordable care. This report recommends changes across the board in these areas to improve the quality of care. Delivering High-Quality Cancer Care: Charting a New Course for a System in Crisis provides information for cancer care teams, patients and their families, researchers, quality metrics developers, and payers, as well as HHS, other federal agencies, and industry to reevaluate their current roles and responsibilities in cancer care and work together to develop a higher quality care delivery system. By working toward this shared goal, the cancer care community can improve the quality of life and outcomes for people facing a cancer diagnosis.
Author: American Association for Cancer Research Publisher: ISBN: 9781734743234 Category : Languages : en Pages :
Book Description
The annual AACR Cancer Progress Report to Congress and the American public is a cornerstone of the AACR's educational and advocacy efforts. This tenth edition of the report highlights how research continues to extend and improve lives, like the lives of the courageous individuals featured in the report who have shared their experiences with cancer. It also underscores how the COVID-19 pandemic has negatively affected cancer science and medicine, as well as how unwavering, bipartisan support from Congress, in the form of robust and sustained annual increases in funding for the NIH, NCI, and FDA, is vital if we are to accelerate the pace of progress against cancer for the benefit of families everywhere.
Author: American Association for Cancer Research
Author: American Association for Cancer Research
Author: American Association for Cancer Research
Author: American Association for Cancer Research
Author: American Association for Cancer Research
Author: 
Author: National Academies of Sciences, Engineering, and Medicine
Author: Paul H. Sugarbaker
Author: American Association for Cancer Research
Author: Committee on Improving the Quality of Cancer Care: Addressing the Challenges of an Aging Population
Author: American Association for Cancer Research